Myotis brandtii (Brandt's bat): 102249345 Help Entry 102249345         CDS       T02920                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb00230   Purine metabolism myb01100   Metabolic pathways myb01522   Endocrine resistance myb04015   Rap1 signaling pathway myb04020   Calcium signaling pathway myb04022   cGMP-PKG signaling pathway myb04024   cAMP signaling pathway myb04062   Chemokine signaling pathway myb04072   Phospholipase D signaling pathway myb04114   Oocyte meiosis myb04211   Longevity regulating pathway myb04213   Longevity regulating pathway - multiple species myb04261   Adrenergic signaling in cardiomyocytes myb04270   Vascular smooth muscle contraction myb04371   Apelin signaling pathway myb04540   Gap junction myb04611   Platelet activation myb04713   Circadian entrainment myb04714   Thermogenesis myb04720   Long-term potentiation myb04723   Retrograde endocannabinoid signaling myb04724   Glutamatergic synapse myb04725   Cholinergic synapse myb04727   GABAergic synapse myb04742   Taste transduction myb04750   Inflammatory mediator regulation of TRP channels myb04911   Insulin secretion myb04912   GnRH signaling pathway myb04913   Ovarian steroidogenesis myb04914   Progesterone-mediated oocyte maturation myb04915   Estrogen signaling pathway myb04916   Melanogenesis myb04918   Thyroid hormone synthesis myb04921   Oxytocin signaling pathway myb04923   Regulation of lipolysis in adipocytes myb04925   Aldosterone synthesis and secretion myb04926   Relaxin signaling pathway myb04927   Cortisol synthesis and secretion myb04928   Parathyroid hormone synthesis, secretion and action myb04934   Cushing syndrome myb04935   Growth hormone synthesis, secretion and action myb04970   Salivary secretion myb04971   Gastric acid secretion myb04972   Pancreatic secretion myb04976   Bile secretion myb05032   Morphine addiction myb05163   Human cytomegalovirus infection myb05166   Human T-cell leukemia virus 1 infection myb05200   Pathways in cancer myb05207   Chemical carcinogenesis - receptor activation myb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102249345 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102249345 (ADCY8)    04371 Apelin signaling pathway     102249345 (ADCY8)    04020 Calcium signaling pathway     102249345 (ADCY8)    04072 Phospholipase D signaling pathway     102249345 (ADCY8)    04024 cAMP signaling pathway     102249345 (ADCY8)    04022 cGMP-PKG signaling pathway     102249345 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102249345 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     102249345 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102249345 (ADCY8)    04062 Chemokine signaling pathway     102249345 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     102249345 (ADCY8)    04923 Regulation of lipolysis in adipocytes     102249345 (ADCY8)    04912 GnRH signaling pathway     102249345 (ADCY8)    04913 Ovarian steroidogenesis     102249345 (ADCY8)    04915 Estrogen signaling pathway     102249345 (ADCY8)    04914 Progesterone-mediated oocyte maturation     102249345 (ADCY8)    04921 Oxytocin signaling pathway     102249345 (ADCY8)    04926 Relaxin signaling pathway     102249345 (ADCY8)    04935 Growth hormone synthesis, secretion and action     102249345 (ADCY8)    04918 Thyroid hormone synthesis     102249345 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     102249345 (ADCY8)    04916 Melanogenesis     102249345 (ADCY8)    04925 Aldosterone synthesis and secretion     102249345 (ADCY8)    04927 Cortisol synthesis and secretion     102249345 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102249345 (ADCY8)    04270 Vascular smooth muscle contraction     102249345 (ADCY8)   09154 Digestive system    04970 Salivary secretion     102249345 (ADCY8)    04971 Gastric acid secretion     102249345 (ADCY8)    04972 Pancreatic secretion     102249345 (ADCY8)    04976 Bile secretion     102249345 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     102249345 (ADCY8)    04727 GABAergic synapse     102249345 (ADCY8)    04725 Cholinergic synapse     102249345 (ADCY8)    04720 Long-term potentiation     102249345 (ADCY8)    04723 Retrograde endocannabinoid signaling     102249345 (ADCY8)   09157 Sensory system    04742 Taste transduction     102249345 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     102249345 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     102249345 (ADCY8)    04213 Longevity regulating pathway - multiple species     102249345 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     102249345 (ADCY8)    04714 Thermogenesis     102249345 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102249345 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     102249345 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102249345 (ADCY8)    05163 Human cytomegalovirus infection     102249345 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     102249345 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102249345 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102249345 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102249345 (ADCY8) Enzymes [BR:myb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102249345 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N TBK1_ULD Motif Other DBs NCBI-GeneID:  102249345 NCBI-ProteinID:  XP_005872848 LinkDB All DBs Position Un AA seq 1036 aa AA seqDB search MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY SGLVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV VLQVVIPRLAVIAINQVVAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLE TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG IPGRIHISKATLDCLNGDYDVEEGHGKERNEFLRKHNIETYLIQQPEDSLLSLPEDIVKE AVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL FITAIQSLLPSSRAMPMAIQFSILIMLHAALVLITTAEDYKCLPLVLRKTCCWINETYLA RNVIIFASILINFLGAILNIYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTE TIYSGLFLRYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAK EEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADF YSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCE DKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKT VNLASRMDSTGVSGRIQVPEETFLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRV QPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNSSGIKGHYARRTLLTPGG PEPGAQAEGPDKSDLP NT seq 3111 nt NT seq  +upstreamnt  +downstreamnt atgaatgtgctggacgtgttgaccaagctcaccctcctggttctccacctgagcctggcc tcggcgcccatggacccgctgaagggcatcctgctcggcttcttcacgggcatcgaggtg gtcatctgcgccctggtggtggtcaggaaggacaccacttcgcacacgtacctgcagtac agcggcctggtcacctgggtggccatgaccacccagatcttggccgcgggccttggctac gggctcctgggcgacggcatcggctacgtgctcttcacgctgttcgccacctacagcatg ctgccgctgccgctcacctgggccatcctggccggcctgggcacttcgctgctgcaggtg gtcctccaagtggtgatcccccgactggcggtcattgccatcaaccaggtggtggcccag gtggtgttattcatgtgcatgaacacggctgggatcttcatcagttacctgtcagaccgc gcccagcgccaggccttcctggagactcggaggtgtgtggaggccaggctgcgcctggag acggaaaaccaaagacaggagcggctcgtgctgtccgtgctgccccgctttgtcgtcctg gagatgatcaacgacatgaccaacgtggaagatgagcacctgcagcaccagttccatcgg atctacatccatcgctatgagaacgtcagtattctttttgcagatgttaaaggatttacc aacctctccacgaccttgtccgctcaggagctggtcaggatgctcaacgagctctttgcc cgattcgatcgactggcccacgagcatcactgtcttcgcatcaagatcctgggggactgc tactactgcgtctccggactgccggagccccgccaggaccacgcccactgctgcgtggaa atgggcctcagcatgatcaaaaccatcaggtatgtgcggtcaaggacgaagcatgacgtc gacatgcgaatcggaatccactcgggctcagtgctgtgtggtgtgttgggcctgcggaag tggcagtttgacgtctggtcttgggacgtggatattgcgaacaaacttgaatctggaggg atccctgggaggattcacatttccaaagccaccctcgactgcctcaacggtgactatgat gtggaagagggccacgggaaagagaggaatgagttcttgcggaagcataacatagagacc tatttaattcagcagccggaggacagtctgctgtcgctgcccgaagacattgtcaaggag gcagtgagctcctcggaccggaggaacagcggggcgacgttcaccgaggggtcctggagc cccgagctgcccttcgacaacatcgtgggtaaacagaacactctggctgccctaacaaga aattcaataaatctacttccaaatcatcttgcacaagctttgcatgtccagtcggggcct gaggaaattaacaagcgaatagaacataccatcgacttgcggagtggcgataaattgaga agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtat tctcaaatgagggacgaagtgttcaagtcaaacttggtgtgtgcgttcatcgttcttctg tttatcacggcaatacagagcttgcttccttcttcaagggctatgccaatggccatccag ttctccatcctgatcatgctgcatgcggctctggtcctcatcaccacggcggaggattac aagtgtttaccactcgtcctgcggaagacttgctgctggatcaacgagacctatttggcc cggaacgtcatcatcttcgcatccatcctgatcaatttcctgggcgccatcctcaatatc tacttcgtcttcacgggcgtgctggccatggtgacctgtgcggttttcctccgactcaac tctgtcctgaagctggccgtgctgctcattatgatcgccatctacgccctgctgaccgag accatctactcaggcctcttcctgcgctatgacaacctgaatcacagtggagaagatttc ctggggaccaaggaggcgtcgctgctgctgatggccatgttcctcctcgctgtgttctac cacggacagcagctggagtacactgcccgcctggacttcctttggcgggttcaggccaaa gaggagatcaacgagatgaaggagctgagggagcacaatgagaacatgctccggaacatc ctgcccagccacgtggcccgccacttcctggagaaggaccgagacaacgaggagctgtat tctcaatcctatgatgctgtcggggtgatgttcgcctccatcccggggtttgcggacttt tactctcagaccgaaatgaataaccaaggcgtggagtgcctgcgcctgctgaatgagatc attgcggacttcgatgagctgctcggcgaagaccggtttcaagacattgaaaagatcaag accattggcagcacctacatggctgtctcaggcctgtcacctgaaaagcagcaatgtgag gacaagtggggacacctgtgcgccctggccgacttctcgctcgccctgacggagagtatc caggagatcaacaagcactcgttcaacaacttcgagctccggatcggcatcagccatggc tcggtggtcgctggcgtcatcggcgctaagaagccgcagtacgacatctggggtaaaacc gtgaacctggccagccgcatggacagcacgggggtcagcggcaggatccaggtcccggag gagacgttcctcatcctgaaggaccagggcttcgccttcgactaccgaggggagatctac gtgaagggcatcagcgagcaggaggggaaaatcaagacgtactttctcctgggcagggtc cagcccaacccgttcatcctgcccccgaggaggctgccggggcagtactcgctggccgcc gtggtcctgggcctcgtccaatccctcaacaggcagcggcagaagcagctcctcaacgag aacaacagctcgggcatcaagggccactacgcccggcggactctgctgacgcccggcggg cccgagcccggcgcccaggccgagggccccgacaagtccgacttgccataa

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