Myotis brandtii (Brandt's bat): 102261014 Help Entry 102261014         CDS       T02920                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb00230   Purine metabolism myb01100   Metabolic pathways myb01522   Endocrine resistance myb04015   Rap1 signaling pathway myb04020   Calcium signaling pathway myb04022   cGMP-PKG signaling pathway myb04024   cAMP signaling pathway myb04062   Chemokine signaling pathway myb04072   Phospholipase D signaling pathway myb04114   Oocyte meiosis myb04211   Longevity regulating pathway myb04213   Longevity regulating pathway - multiple species myb04261   Adrenergic signaling in cardiomyocytes myb04270   Vascular smooth muscle contraction myb04371   Apelin signaling pathway myb04540   Gap junction myb04611   Platelet activation myb04713   Circadian entrainment myb04714   Thermogenesis myb04723   Retrograde endocannabinoid signaling myb04724   Glutamatergic synapse myb04725   Cholinergic synapse myb04727   GABAergic synapse myb04740   Olfactory transduction myb04750   Inflammatory mediator regulation of TRP channels myb04911   Insulin secretion myb04912   GnRH signaling pathway myb04913   Ovarian steroidogenesis myb04914   Progesterone-mediated oocyte maturation myb04915   Estrogen signaling pathway myb04916   Melanogenesis myb04918   Thyroid hormone synthesis myb04921   Oxytocin signaling pathway myb04923   Regulation of lipolysis in adipocytes myb04925   Aldosterone synthesis and secretion myb04926   Relaxin signaling pathway myb04927   Cortisol synthesis and secretion myb04928   Parathyroid hormone synthesis, secretion and action myb04934   Cushing syndrome myb04935   Growth hormone synthesis, secretion and action myb04962   Vasopressin-regulated water reabsorption myb04970   Salivary secretion myb04971   Gastric acid secretion myb04972   Pancreatic secretion myb04976   Bile secretion myb05032   Morphine addiction myb05163   Human cytomegalovirus infection myb05166   Human T-cell leukemia virus 1 infection myb05200   Pathways in cancer myb05207   Chemical carcinogenesis - receptor activation myb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102261014 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102261014 (ADCY3)    04371 Apelin signaling pathway     102261014 (ADCY3)    04020 Calcium signaling pathway     102261014 (ADCY3)    04072 Phospholipase D signaling pathway     102261014 (ADCY3)    04024 cAMP signaling pathway     102261014 (ADCY3)    04022 cGMP-PKG signaling pathway     102261014 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102261014 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     102261014 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102261014 (ADCY3)    04062 Chemokine signaling pathway     102261014 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     102261014 (ADCY3)    04923 Regulation of lipolysis in adipocytes     102261014 (ADCY3)    04912 GnRH signaling pathway     102261014 (ADCY3)    04913 Ovarian steroidogenesis     102261014 (ADCY3)    04915 Estrogen signaling pathway     102261014 (ADCY3)    04914 Progesterone-mediated oocyte maturation     102261014 (ADCY3)    04921 Oxytocin signaling pathway     102261014 (ADCY3)    04926 Relaxin signaling pathway     102261014 (ADCY3)    04935 Growth hormone synthesis, secretion and action     102261014 (ADCY3)    04918 Thyroid hormone synthesis     102261014 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     102261014 (ADCY3)    04916 Melanogenesis     102261014 (ADCY3)    04925 Aldosterone synthesis and secretion     102261014 (ADCY3)    04927 Cortisol synthesis and secretion     102261014 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102261014 (ADCY3)    04270 Vascular smooth muscle contraction     102261014 (ADCY3)   09154 Digestive system    04970 Salivary secretion     102261014 (ADCY3)    04971 Gastric acid secretion     102261014 (ADCY3)    04972 Pancreatic secretion     102261014 (ADCY3)    04976 Bile secretion     102261014 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102261014 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     102261014 (ADCY3)    04727 GABAergic synapse     102261014 (ADCY3)    04725 Cholinergic synapse     102261014 (ADCY3)    04723 Retrograde endocannabinoid signaling     102261014 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     102261014 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     102261014 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     102261014 (ADCY3)    04213 Longevity regulating pathway - multiple species     102261014 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     102261014 (ADCY3)    04714 Thermogenesis     102261014 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102261014 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     102261014 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102261014 (ADCY3)    05163 Human cytomegalovirus infection     102261014 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     102261014 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102261014 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102261014 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102261014 (ADCY3) Enzymes [BR:myb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102261014 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA DUF3810 Peptidase_S49_N Motif Other DBs NCBI-GeneID:  102261014 NCBI-ProteinID:  XP_014402102 LinkDB All DBs Position Un AA seq 1101 aa AA seqDB search MPLSSGDTVHTSEQAGAEGLCMAPPLSPPATLSLLQISVRSSGPCLCLPGFLRLTFVPAS LESLYQTYFKRQRHETLLVLVVFAALFDCHVVVLCAVVFSADKLAPLAVAGVGLALDILL FVLCRKGLLPSRVTRKVVPYLLWLLITAQIFSYLGLSFPGAHAASDTVGWQAFFVFSFFI TLPLSLGPIVVISVVSCVAHTLIVGVTVAQQQQDRLKGMQLLREILANVFLYLCAIVVGI MSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQ KDQQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLAAKYHQL RIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVL GGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEGGSRCDY LEEKGIETYLIIASKPEVKKTASQNGLNSSADNPSFPNPHRRLRLQDLADRVVDASEDEH ELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPELETRYSVEKEKQSGAAFSCSCVVLL CAALVEIVIDPWLMTNYVTFVVGELLLLVLTVCSLAAIFPRAFPKKLVAFSTWIDRTRWA RNTWAMLAIFILVMANVVDVLSCLQYYMGPNNGTSGMATEDGCMENPKYYNYVAVLSLIA TIMLVQVSHMVKLTLMLLVTGAVAVINLCAWRPIFDEYDRRRFQEHGVPLVALEKMQILS TPGLNGTGRLPLVPSKYTMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYE MRRWNEALVTNMLPDHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINN GGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEE KSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDI WGNTVNVTSRMESTGVMGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRD KPAAFPNGSSVTLPHQVVDNS NT seq 3306 nt NT seq  +upstreamnt  +downstreamnt atgcccctctcctcgggtgacacagtccacacctctgagcaggctggagctgaggggctc tgtatggcaccccctctcagcccacctgctactctgtcgctgctgcagatctccgtgcgg agctcggggccctgcctctgcctgcccggcttcctgcggctgaccttcgtgcccgcgtcc ctggagagcctgtaccagacctacttcaagaggcagcgccacgagaccctgctggtgctg gtggtcttcgccgcgctcttcgactgccacgtggtggtcctgtgcgccgtggtcttctcc gcggacaagctggctcccctcgcggtggccggcgtcgggctggcgttggacatcctcctc ttcgtgctgtgcaggaaggggctgctccccagccgggtcacccggaaggtggtgccctac ctgctgtggctgctgatcaccgcccagatcttctcctacctgggcctgagcttccccggc gcccacgcggccagcgacacggtgggctggcaggccttcttcgtcttctccttcttcatc acgctgcccctcagcctcggccccatcgtcgtcatctcggtggtgtcctgtgtggcacac acgctcattgtgggggtcaccgtggcccagcagcagcaggacaggctgaaggggatgcag ttgctgagagagatcctggccaacgtcttcctctacctgtgcgccatcgtcgtgggcatc atgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccagtcg ctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctgatgctgtcc atcctgcccaagcatgtggctgacgagatgctaaaggacatgaagaaggacgagagccag aaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatcctc ttcgcggacatcgtgggcttcacccagctgtcttccacctgcagcgcccaggagctcgtg aagctgctcaacgagctctttgcccgcttcgacaagctggcggccaaataccaccagctg cggattaagatcctgggcgactgttactactgcatctgcggcctgcctgactaccgggag gaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtatgtg cgggagaagacgaagaccggggtggacatgcgtgtgggggtgcacacgggcactgtgctg gggggcgtcctgggccagaagcgctggcagtatgacgtgtggtctaccgatgtcactgtg gccaacaagatggaggccggcggcatccccgggcgcgtgcacatctcccagagcaccctg gactgcctgaaaggagagttcgacgtggagcccggcgaggggggcagccgctgcgattac ctagaggagaagggcattgagacctacctcatcatcgcgtccaagccagaggtgaagaaa accgcctcccagaatggcctcaacagctcggccgacaacccctcgttccccaaccctcac cggaggctgcgccttcaggacctggctgatcgggtggtggacgcctctgaggacgagcac gagctcaaccagctcctcaacgaggccctgctcgagcgggagtccgcgcaggtagtgaag aagagaaacaccttcctcctgtccatgcgcttcatggaccccgagctggaaacccgctac tcggtggagaaggaaaagcagagcggggccgccttcagctgctcctgcgtcgtgctgctc tgcgcggccctggtggagatcgtcatcgacccctggctgatgaccaactatgtgaccttt gtggttggggagcttctgcttctggtcctgaccgtctgctcgctggctgccatctttccc cgggcctttcctaagaagcttgtggccttctcgacgtggattgaccggacacgctgggcc aggaacacctgggccatgttagccatcttcattctggttatggcaaatgttgtggacgtg ctgagctgcctgcaatactacatgggacccaacaatggcacctcggggatggcgacagag gatggctgcatggagaaccccaagtattacaactacgtcgccgtgctgtccctcatcgcc accatcatgctggtgcaggtcagccacatggtgaagctcaccctcatgctgcttgtcacg ggcgctgtggctgtcatcaacctctgtgcctggcgccccatctttgatgaatatgaccgc agacgtttccaggaacacggcgttcctctggtcgccttagagaagatgcagatactctcc actccagggctcaatggcactggcaggctgcccctggtgccttctaagtacacgatgaca gtgatgatcttcgtcatgatgctgagcttctactacttctcccgccacgtggaaaaactc gcacggacactgttcttgtggaagattgaggtccatgaccagaaggaacgtgtctacgag atgcgacgctggaatgaggccctggtcaccaacatgttgcccgaccatgtggcacgccat ttcctagggtccaagaagagagatgaggagctgtatagccagtcttatgatgagattgga gtcatgtttgcctccctgcccaactttgctgacttctacacagaggagagcatcaataat ggtggcattgagtgtctgcgcttcctcaatgagatcatctcagattttgactctcttcta gacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagtacctatatggca gcttccggagtcaccccagatgtcaacaccaacggctttaccagctccagcaaggaggaa aagtcagacaaggagcgctggcagcacctggctgatctggctgactttgcactagccatg aaggatacgcttacaaacatcaacaaccagtccttcaacaacttcatgttgcgcataggc atgaacaaaggaggggtcctggctggggtcattggagcccggaaaccacactacgacatt tggggcaatacagtcaacgtgaccagcaggatggagtccacaggggtcatgggtaacatt caggtggtagaagaaacacaagccatccttcgagagtacggctttcgctttgtgaggcgg gggcccatctttgtgaaagggaagggggagctgctaacctttttcttgaaggggcgtgat aagccagccgccttcccgaatggctcctctgtgaccctgccccaccaggtggtagacaac tcctga

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