Nannospalax galili (Upper Galilee mountains blind mole rat): 103729731
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Entry
103729731 CDS
T03372
Symbol
Hk1
Name
(RefSeq) hexokinase 1
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00010
Glycolysis / Gluconeogenesis
ngi00051
Fructose and mannose metabolism
ngi00052
Galactose metabolism
ngi00500
Starch and sucrose metabolism
ngi00520
Amino sugar and nucleotide sugar metabolism
ngi00524
Neomycin, kanamycin and gentamicin biosynthesis
ngi01100
Metabolic pathways
ngi01200
Carbon metabolism
ngi01250
Biosynthesis of nucleotide sugars
ngi04066
HIF-1 signaling pathway
ngi04910
Insulin signaling pathway
ngi04930
Type II diabetes mellitus
ngi04973
Carbohydrate digestion and absorption
ngi05230
Central carbon metabolism in cancer
Module
ngi_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ngi_M00549
Nucleotide sugar biosynthesis, glucose => UDP-glucose
ngi_M00892
UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103729731 (Hk1)
00051 Fructose and mannose metabolism
103729731 (Hk1)
00052 Galactose metabolism
103729731 (Hk1)
00500 Starch and sucrose metabolism
103729731 (Hk1)
00520 Amino sugar and nucleotide sugar metabolism
103729731 (Hk1)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
103729731 (Hk1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103729731 (Hk1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103729731 (Hk1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
103729731 (Hk1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103729731 (Hk1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103729731 (Hk1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103729731 (Hk1)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
103729731 (Hk1)
Membrane trafficking [BR:
ngi04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
103729731 (Hk1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Sec23_helical
Motif
Other DBs
NCBI-GeneID:
103729731
NCBI-ProteinID:
XP_008826029
LinkDB
All DBs
Position
Un
AA seq
973 aa
AA seq
DB search
MPRLGCCGGGAKRGGGGGGGGGGGAAELPSEDHCSPGLRRSHRPHVCFPAPPTATMIAAQ
LLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDILTRFKKEMKNGLSRDYNPTASVKMLP
TFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVNMESEAYETPENIVHGSGSQ
LFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADV
VKLLNKSIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHI
DLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGLYIGEL
VRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEQNKEGIQNAREILTRLGVEPSD
DDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSR
RFHKTLRRLVPDCDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLARFRLTKQTLL
EVKKRMRVEMDLGLSKQTHDKATVKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKI
RSGKKRTVEMHNKIYSIPTEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFP
CKQTSLDCGILITWTKGFKASDCVGHDVATLLRDAIKRREEFDLDVVAMVNDTVGTMMTC
AYEEPSCEVGLIVGTGSNACYMEEMRNVEVLEGNQGQMCINMEWGAFGDNGCMDDIRTEY
DRVVDEFSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETK
FLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKI
RENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCSVSFLLSEDGSGKGAALIT
AVGVRLRGEITSS
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgccgcgcctcgggtgctgcgggggaggagccaagagaggcggaggaggaggaggagga
ggaggaggaggagctgcggagctgccctcggaggaccactgctcaccggggctgcggaga
agccaccggccccacgtctgcttccccgcgccgccgaccgccaccatgatcgccgcgcag
ctcctggcctattacttcaccgagctgaaggatgaccaagtcaaaaagattgataagtat
ctgtatgccatgcggctctctgatgaaactctgatagatattctgacccgcttcaagaag
gagatgaagaatggcctttccagggattataatccaacagcctcagtcaagatgttaccg
acctttgtaaggtccattcctgatggttcagaaaagggggatttcattgccctggatctt
ggcgggtcttcctttcgaatcctgagggtacaagtgaatcatgagaaaaaccagaatgtc
aacatggagtcggaggcctacgagaccccagagaacatcgtgcatggcagcggaagccag
ctttttgatcatgtcgctgagtgcctgggagacttcatggagaaaaggaagatcaaggac
aagaagttgcctgtggggttcacattttctttcccctgccgacaatccaaaatagatgag
gctgttctgatcacatggacaaagcggttcaaagccagcggtgtggaaggggccgatgtg
gtcaagctcctgaataaatccatcaagaagcgaggggactatgatgccaacattgtagct
gtggtaaatgatacagtggggaccatgatgacttgtggttatgatgaccagcagtgtgaa
gtgggcctgatcattggcactggcaccaacgcttgctatatggaggaactgagacatatt
gacctggtggaaggtgatgaggggaggatgtgcatcaacacagaatggggggccttcggg
gatgacggttccctggaagacatccgcactgagtttgacagagagttagaccggggatcc
ctcaaccctggaaaacagctgttcgagaagatggtcagtggcttgtacataggggagctg
gtccgcttgatcctggtcaagatggccaaagaaggtctcttatttgaagggcgcatcacc
ccagagctgctcaccagagggaagttcaataccagcgatgtgtcagccattgaacagaat
aaggaaggcatccaaaatgccagagaaatcttgacccgcctgggagtggagccctctgat
gatgactgtgtttcggtccagcacgtgtgcaccattgtctcctttcgctcagccaacctg
gtggctgccacgctgggtgccatcttgaaccgcctgcgtgacaacaaaggtacccccagg
ctgcggaccacggttggtgtggacggctctctctacaagacacacccccagtattcccga
cgtttccataagaccctgaggcgcctggtgcccgactgcgacgtgcgcttcctcctctcg
gagagtggcagtggcaagggtgctgccatggtgactgcagtggcctaccgcctggccgag
cagcaccggcagatcgaggagaccctggcccgcttccgcctcaccaagcagacactgctg
gaggtgaagaagaggatgcgtgttgagatggatttggggctgagtaagcagacccatgac
aaagctacagtcaagatgctgccttcttttgtccggagcattccagatgggactgagcac
ggcgactttttggccttggatcttggaggaacaaacttccgagtcctgctagtgaaaatc
cgaagcgggaaaaagagaacagtggagatgcacaataagatctattccattcccacggaa
atcatgcagggcaccggagaggagctgtttgaccacatcgtctcctgcatctccgacttc
ctggactacatggggatcaaaggcccccggatgcctctgggcttcaccttctcttttccc
tgcaaacagacaagcctggattgtggaatcctgatcacctggacaaagggtttcaaggcc
agtgactgcgtgggtcatgatgtagccactttgttaagggatgcgataaaaaggagagag
gaatttgacctggatgtggtggctatggtcaatgacactgtgggaaccatgatgacctgt
gcatatgaggaacccagctgtgaagttggacttattgtagggactggctccaatgcctgc
tacatggaggagatgaggaacgtggaggtgctggaagggaaccaggggcagatgtgcatc
aacatggagtggggcgcctttggggacaacgggtgtatggatgacatcagaacggagtat
gacagagtggtggatgaattctctctgaatgccgggaaacaaaggtatgaaaagatgatc
agtggtatgtacctgggggaaatcgtccgcaacatcttgattgacttcaccaagaaggga
ttcctcttccggggacagatctctgagcctctcaagactcggggcatctttgagaccaag
tttctctctcagattgagagtgaccgattagcgctgctccaagtgcgggccatcctccag
cagctgggtctgaacagcacgtgtgatgacagtatccttgtcaagaccgtatgcggggtg
gtgtccaagagggccgcacagctgtgtggcgcaggcatggctgccgtggtggaaaagatc
cgagagaacagagggctggaccatctgaatgtgactgtgggagtggatgggacactctac
aaacttcatccacacttctcaagaatcatgcaccaaaccgtgaaggaactgtcaccaaag
tgtagtgtgtccttcctcctgtctgaagatggcagtggcaagggggctgccctcatcaca
gctgtgggcgtgcggctcagaggagaaattacgagcagctaa
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