Nannospalax galili (Upper Galilee mountains blind mole rat): 103743923
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Entry
103743923 CDS
T03372
Symbol
Adcy8
Name
(RefSeq) adenylate cyclase 8
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi01522
Endocrine resistance
ngi04015
Rap1 signaling pathway
ngi04020
Calcium signaling pathway
ngi04022
cGMP-PKG signaling pathway
ngi04024
cAMP signaling pathway
ngi04062
Chemokine signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04114
Oocyte meiosis
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04261
Adrenergic signaling in cardiomyocytes
ngi04270
Vascular smooth muscle contraction
ngi04371
Apelin signaling pathway
ngi04540
Gap junction
ngi04611
Platelet activation
ngi04713
Circadian entrainment
ngi04714
Thermogenesis
ngi04720
Long-term potentiation
ngi04723
Retrograde endocannabinoid signaling
ngi04724
Glutamatergic synapse
ngi04725
Cholinergic synapse
ngi04727
GABAergic synapse
ngi04742
Taste transduction
ngi04750
Inflammatory mediator regulation of TRP channels
ngi04911
Insulin secretion
ngi04912
GnRH signaling pathway
ngi04913
Ovarian steroidogenesis
ngi04914
Progesterone-mediated oocyte maturation
ngi04915
Estrogen signaling pathway
ngi04916
Melanogenesis
ngi04918
Thyroid hormone synthesis
ngi04921
Oxytocin signaling pathway
ngi04923
Regulation of lipolysis in adipocytes
ngi04925
Aldosterone synthesis and secretion
ngi04926
Relaxin signaling pathway
ngi04927
Cortisol synthesis and secretion
ngi04928
Parathyroid hormone synthesis, secretion and action
ngi04934
Cushing syndrome
ngi04935
Growth hormone synthesis, secretion and action
ngi04970
Salivary secretion
ngi04971
Gastric acid secretion
ngi04972
Pancreatic secretion
ngi04976
Bile secretion
ngi05032
Morphine addiction
ngi05163
Human cytomegalovirus infection
ngi05166
Human T-cell leukemia virus 1 infection
ngi05200
Pathways in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103743923 (Adcy8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
103743923 (Adcy8)
04371 Apelin signaling pathway
103743923 (Adcy8)
04020 Calcium signaling pathway
103743923 (Adcy8)
04072 Phospholipase D signaling pathway
103743923 (Adcy8)
04024 cAMP signaling pathway
103743923 (Adcy8)
04022 cGMP-PKG signaling pathway
103743923 (Adcy8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
103743923 (Adcy8)
09144 Cellular community - eukaryotes
04540 Gap junction
103743923 (Adcy8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103743923 (Adcy8)
04062 Chemokine signaling pathway
103743923 (Adcy8)
09152 Endocrine system
04911 Insulin secretion
103743923 (Adcy8)
04923 Regulation of lipolysis in adipocytes
103743923 (Adcy8)
04912 GnRH signaling pathway
103743923 (Adcy8)
04913 Ovarian steroidogenesis
103743923 (Adcy8)
04915 Estrogen signaling pathway
103743923 (Adcy8)
04914 Progesterone-mediated oocyte maturation
103743923 (Adcy8)
04921 Oxytocin signaling pathway
103743923 (Adcy8)
04926 Relaxin signaling pathway
103743923 (Adcy8)
04935 Growth hormone synthesis, secretion and action
103743923 (Adcy8)
04918 Thyroid hormone synthesis
103743923 (Adcy8)
04928 Parathyroid hormone synthesis, secretion and action
103743923 (Adcy8)
04916 Melanogenesis
103743923 (Adcy8)
04925 Aldosterone synthesis and secretion
103743923 (Adcy8)
04927 Cortisol synthesis and secretion
103743923 (Adcy8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
103743923 (Adcy8)
04270 Vascular smooth muscle contraction
103743923 (Adcy8)
09154 Digestive system
04970 Salivary secretion
103743923 (Adcy8)
04971 Gastric acid secretion
103743923 (Adcy8)
04972 Pancreatic secretion
103743923 (Adcy8)
04976 Bile secretion
103743923 (Adcy8)
09156 Nervous system
04724 Glutamatergic synapse
103743923 (Adcy8)
04727 GABAergic synapse
103743923 (Adcy8)
04725 Cholinergic synapse
103743923 (Adcy8)
04720 Long-term potentiation
103743923 (Adcy8)
04723 Retrograde endocannabinoid signaling
103743923 (Adcy8)
09157 Sensory system
04742 Taste transduction
103743923 (Adcy8)
04750 Inflammatory mediator regulation of TRP channels
103743923 (Adcy8)
09149 Aging
04211 Longevity regulating pathway
103743923 (Adcy8)
04213 Longevity regulating pathway - multiple species
103743923 (Adcy8)
09159 Environmental adaptation
04713 Circadian entrainment
103743923 (Adcy8)
04714 Thermogenesis
103743923 (Adcy8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103743923 (Adcy8)
05207 Chemical carcinogenesis - receptor activation
103743923 (Adcy8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103743923 (Adcy8)
05163 Human cytomegalovirus infection
103743923 (Adcy8)
09165 Substance dependence
05032 Morphine addiction
103743923 (Adcy8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
103743923 (Adcy8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103743923 (Adcy8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
103743923 (Adcy8)
Enzymes [BR:
ngi01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
103743923 (Adcy8)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
103743923
NCBI-ProteinID:
XP_008843712
UniProt:
A0A8C6W2E4
LinkDB
All DBs
Position
Un
AA seq
1250 aa
AA seq
DB search
MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFILGHRGGGGG
SGGSRKTSNPAGSGPNHHAPQLSGDSALPLYSLGPGERAHNTGSTKVFPERSGSGSGSGS
GGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKS
EVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTY
LQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSL
LQVILQLVIPRLPVFSINQVLAQGVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARL
RLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVK
GFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHC
CVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLE
SGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDI
VKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQ
SGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFI
VLLFITAIQSLLPSSRLVPMTIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINET
YLARNVIIFASILINFLGAVLNILWCDFDKSISLKNLTFNSSAGFTDICSYPEYFVFTGV
LAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNVNHSGEDFLGTKEAS
LLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVAR
HFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDEL
LGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALAESIQEINRHS
FNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILK
DQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQ
SLNRQRQKQLLNENSNTGIIKGHYNRRTLLTPSGPEPGAQAEDSDKSDLP
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
atggagctctcggatgtgcgctgccttagcggcagcgaggaactctacaccattcacccg
acgcccccggccggcgacggcgggagcggttctcggccgcaaaggttgctgtggcagacg
gcggtgcggcacatcaccgagcagcgcttcatccttgggcaccggggcggcggcggcggg
agcgggggctcacgcaaaacctctaaccctgccggcagcgggcccaaccaccacgcgccg
cagctgtctggcgactcggcgctgcccctctattctctgggcccgggggagagagcgcac
aacaccggcagcacgaaagtcttcccggaacgcagcgggagcggcagtggcagtggcagc
ggaggcgggggcgatctgggcttcctgcaccttgactgtgccccgagcaactcagatttc
ttccttaatgggggctacagctaccgaggggttattttccccaccctgcgcaactcgttc
aagtctcgggatctggagcgtctctaccagcgctatttcctgggtcagaggcgcaaatct
gaggtggtgatgaacgtgctggatgtgctaaccaaactcacgctcttggtcctccacttg
agcctagcctcggccccaatggacccgctcaagggcatcttgctgggcttcttcactggc
atcgaggtggtgatctgcgcactcgtggtggtcaggaaggacaccacctcgcatacctac
ctgcaatacagcggcgtggtcacttgggtggctatgaccacccagatcctggcagccggc
cttggctatgggcttttgggagatggcataggctatgtactctttacgctcttcgccacc
tacagcatgcttccgctgccgctcacctgggccatcctagccggcctgggcacttcgctg
ctacaagtgatcctccaactggtcatcccccgactgccggtcttttccatcaaccaggtc
ttggcccagggggtgctattcatgtgcatgaacacagctggaatcttcatcagttacctg
tccgaccgtgcccagcgccaagccttcctggagacacggaggtgtgtggaggccaggctg
cgcctggagacagagaaccagagacaggagcgactcgtgctgtctgttctccccaggttt
gtggtcctggaaatgatcaatgacatgaccaatgtggaggacgagcacctgcagcatcag
ttccatcgcatctatattcatcgctatgagaatgtcagtattctttttgcagatgttaaa
ggatttaccaacctctctacgaccttgtctgctcaggagctggtcaggatgctcaacgag
ctctttgccagatttgatcggctggcccatgagcatcattgccttcgcattaaaatccta
ggggactgctactactgcgtctctggactgcctgagccccgccaggaccatgcccactgc
tgtgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtgagatccagaactaag
catgatgttgacatgcgaattggaatccattccggctcagtgctatgtggtgtgttgggc
ttgcggaaatggcagtttgatgtctggtcttgggatgtggacatagcgaacaaactggaa
tctggaggaatccctgggagaattcacatttccaaagccacactggactgcctcaatggt
gactacaatgtggaagagggccatggtaaagagaggaatgaattcttaaggaagcataat
atagagacctatttgattaagcagcctgaggagagtttgctgtccttgcctgaagacatt
gtcaaggagtctgtgagttcctcagacaggagaaacagtggggccacattcactgaagga
tcctggagcccagaactgccttttgataacatcgtgggaaaacagaatactctggctgcc
ctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtccag
tctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgat
aaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctggag
cacaagtattctcaaatgagggatgaagtgttcaagtcaaacttggtctgtgcgtttata
gttcttctgtttatcaccgcaattcaaagcttgcttccttcttcaagactggtgccgatg
accattcagttctccatcctcatcatgctgcactctgccctggtcctcatcacgacagca
gaagactacaagtgtctgcccctcgtcctccggaaaacctgctgttggatcaatgaaacc
tatctggcccggaacgtcatcatctttgcttccatcttgattaatttcctgggtgccgtc
ctaaatattctgtggtgtgattttgacaagtcgatatccttgaagaacctgactttcaat
tcctcagctgggtttacagatatctgctcctacccagagtacttcgttttcactggagta
ttggccatggtgacctgtgcagtttttctccggcttaactccgtcctgaagctggctgtg
ctgctaattatgatcgccatttacgccctgctgactgagaccatctacgcaggtcttttt
ctgcgttatgacaacgtgaaccacagtggagaagatttcctggggaccaaagaggcgtcc
ctgctgctgatggccatgttcctccttgctgtgttctaccatggacagcagctggagtac
acagcccgcctggacttcctgtggcgagtacaggccaaagaggagatcaatgagatgaag
gaacttagagaacacaatgaaaacatgctgcgcaatatcttgcccagccacgtggcccgt
catttcctggagaaggaccgagacaatgaggaactgtattctcagtcctatgatgctgtt
ggggtgatgtttgcctccatcccaggatttgcagacttttactctcagactgaaatgaac
aaccaaggagtggaatgcctgcgcttgctgaatgagatcatcgctgactttgacgagttg
cttggagaagaccggtttcaagacattgaaaaaattaagaccattggtagcacctacatg
gctgtctcaggcctgtcaccagaaaaacagcaatgtgaagacaagtggggacatttgtgt
gccctggctgacttctctctagcactggctgaaagcatacaagagatcaacaggcattcg
ttcaacaatttcgagctccggattggcatcagccatggctcagtggtagctggtgtgatc
ggcgctaagaaaccacagtatgacatttggggtaaaactgtgaacttggcaagccggatg
gacagcacaggagtgagtggccggatccaagtccctgaggagacctatctcatcctgaag
gaccagggcttcgcctttgactaccgaggggagatctatgtgaagggcatcagtgagcaa
gaagggaaaatcaaaacatactttcttctgggaagagtccaacccaacccatttatcttg
cctccaagaagactacccgggcagtactccctggctgcggttgtccttggccttgtccag
tctctcaataggcaaaggcagaaacaactactcaatgaaaacagcaacacaggcatcatc
aagggccattacaaccggcggactttgttgacacccagtgggccagagcctggagcccaa
gctgaagacagcgacaaatccgatttgccataa
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integrated database retrieval system
