Candidatus Nitrosopumilus sp. SW: Nisw_07340
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Entry
Nisw_07340 CDS
T06175
Name
(GenBank) M20/M25/M40 family metallo-hydrolase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
niw
Candidatus Nitrosopumilus sp. SW
Pathway
niw00470
D-Amino acid metabolism
niw01100
Metabolic pathways
niw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
niw00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
Nisw_07340
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Nisw_07340
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
niw01011
]
Nisw_07340
Enzymes [BR:
niw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
Nisw_07340
Peptidoglycan biosynthesis and degradation proteins [BR:
niw01011
]
Precursor biosynthesis
Amino acid ligase
Nisw_07340
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Peptidase_M20
ATP-grasp_4
ATP-grasp_3
CPSase_L_D2
GARS_A
RimK
ATP-grasp
ATPgrasp_Ter
ATPgrasp_ST
Ribosomal_S30AE
Motif
Other DBs
NCBI-ProteinID:
QDI89349
UniProt:
A0A514LBX5
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All DBs
Position
1215537..1217699
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AA seq
720 aa
AA seq
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MKVSLIYNEKKIDPDDVINVFGMTTKEHYSTKAVERVARALEKGGHSVKVIEGDIHLADE
LREFMPKVVSGEKPGMVFNMAYGIQGQNRYTHVPAMMEMLGIPYIGSGPAGHAIVQDKVM
TKIVLQKNNISTPGFWVFKTPDDKFDDLVFPVIVKPKLESTSMGMEVVDNWNDLRKAVAI
QIEKFQQDILVEQFVSGREFAVGLIGNSPNIEVLPIVEIDLGDPDKIQTNDDKKKTGGVD
KICPAKLSKEKTEEMKQMCIQAFTALGLNDYSRVDFRMDKDENLYILELNSMASLGMGGS
LFYAAKTAGYTYESLINKILDVATIRYFGSSQPTETEADLTQPLRVVARTYLRGHLQNQK
DTLRDFVNLNTHVRNVDNVNKLGTMLSRRLKHLGFNERLHKQFEVGDIHYFKNHEEEKND
VLIISHMDTHYGPNDLISYFEDDDRIYGSGIAESKGGLIVMLGALHALRFAKRLKKIKCG
VLLTTDDSLGGRFSKKIVQQYSKKSKYIIGLKSASKDGGIITTCYGRNDYQIRFTAPNST
SSDIHGIIPILGKKITAIEKLSKDEKNYRLRTTSVIAQGTHGHTPNYATLSIICSFKTPS
LGKTMDSKIRTIMKKKESGQKNLEVAINQIQTRPPVIEEESDKKFYEMVEDLAEKHELKI
RRHEQIMSSDISNVPSRLPALDGFGPIGHKYRSTQEYILHDSITERSALLASVLYRCGGN
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtctctctaatctataatgagaaaaaaatcgacccagatgatgttatcaatgtt
tttggaatgactacaaaagagcattacagtacaaaagctgttgagagagttgcaagagct
cttgaaaaaggaggtcactctgtaaaagtcattgaaggtgatattcaccttgctgatgaa
ttacgtgaatttatgccaaaagtagtctcaggtgaaaaacctgggatggttttcaacatg
gcatatggcattcaaggacaaaacaggtacactcatgttcctgcaatgatggaaatgctt
ggtattccttacataggttctggtcctgcaggtcatgcaattgtgcaagataaggtgatg
acaaaaatcgttttacaaaaaaataatatttccactcctggtttttgggtattcaagaca
cctgatgataaatttgatgatttagtttttccagtaattgtaaaaccaaaattagaatct
acttctatggggatggaggttgtggataattggaatgatttacgaaaagcagtggcgata
caaattgaaaaatttcaacaagatattctagtagaacagtttgtttctggacgagaattt
gcagtaggattaattggaaatagtccaaacatcgaagttcttccaatagttgaaattgac
ttgggtgatcctgacaaaattcaaacaaatgatgataaaaagaaaacaggtggagttgat
aaaatctgtcctgcaaaactatccaaagaaaaaacagaagaaatgaaacagatgtgtatt
caagcatttacggcattaggtcttaatgactacagcagagttgattttagaatggataaa
gatgagaatctttacattttagaactaaattctatggcaagtctgggcatgggcggttct
ttgttttatgctgcaaaaacagctgggtatacctatgaatctctaatcaataaaatttta
gacgtcgcaaccattagatattttggctcatcacaaccaacagagactgaagcagatctt
actcaaccactccgtgttgttgctcgaacttatcttagaggtcatctgcaaaaccaaaag
gacactttacgagattttgttaatctgaacacacacgtacgtaatgtcgataatgtgaat
aaattaggtacaatgctatctcggagattgaaacatttgggattcaatgagcgtttgcac
aagcagttcgaagttggtgacatacattattttaaaaatcatgaagaagaaaaaaatgac
gtcctgataatatctcatatggatactcactatgggccaaatgatcttatctcgtatttt
gaagatgatgataggatttatgggtctggtatagctgaaagtaaaggtggtttgattgta
atgttaggagcattacatgctttacgttttgcaaagagactcaagaaaatcaaatgcgga
gtgttgcttacaactgatgatagtttgggaggacgttttagcaaaaaaattgttcaacaa
tattccaaaaaatcaaaatacattattggattaaaatctgcaagcaaagatggtggcata
attacaacatgttatgggagaaatgattatcaaattagatttacagcccctaactccaca
tcctcagacattcatggaataattccaatacttggaaaaaagattactgcaattgaaaaa
ctttcaaaagatgaaaagaattatcgtctaagaaccacttctgttattgcacaaggtact
catggacatactccaaattatgctaccttgtctataatttgcagtttcaaaactccttca
ttgggaaaaacaatggattctaaaatcagaactattatgaagaaaaaagaatctggtcaa
aagaacttggaagttgcaataaaccaaatacaaacaagacctccagtcattgaagaggaa
tctgacaaaaaattctatgagatggttgaagatttagctgaaaaacatgaattaaaaata
agacgacatgaacagataatgtcttcagatattagtaatgtgccttcaagattacctgca
ttagatggatttggtcctattggtcacaaatatcgctctacacaagaatacatacttcat
gatagcataacagagcgttcagctctacttgcatctgttttgtataggtgtggtggaaat
tga
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