Nomascus leucogenys (northern white-cheeked gibbon): 100592592
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Entry
100592592 CDS
T03265
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8 isoform X1
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00230
Purine metabolism
nle01100
Metabolic pathways
nle01522
Endocrine resistance
nle04015
Rap1 signaling pathway
nle04020
Calcium signaling pathway
nle04022
cGMP-PKG signaling pathway
nle04024
cAMP signaling pathway
nle04062
Chemokine signaling pathway
nle04072
Phospholipase D signaling pathway
nle04114
Oocyte meiosis
nle04211
Longevity regulating pathway
nle04213
Longevity regulating pathway - multiple species
nle04261
Adrenergic signaling in cardiomyocytes
nle04270
Vascular smooth muscle contraction
nle04371
Apelin signaling pathway
nle04540
Gap junction
nle04611
Platelet activation
nle04713
Circadian entrainment
nle04714
Thermogenesis
nle04720
Long-term potentiation
nle04723
Retrograde endocannabinoid signaling
nle04724
Glutamatergic synapse
nle04725
Cholinergic synapse
nle04727
GABAergic synapse
nle04742
Taste transduction
nle04750
Inflammatory mediator regulation of TRP channels
nle04911
Insulin secretion
nle04912
GnRH signaling pathway
nle04913
Ovarian steroidogenesis
nle04914
Progesterone-mediated oocyte maturation
nle04915
Estrogen signaling pathway
nle04916
Melanogenesis
nle04918
Thyroid hormone synthesis
nle04921
Oxytocin signaling pathway
nle04923
Regulation of lipolysis in adipocytes
nle04925
Aldosterone synthesis and secretion
nle04926
Relaxin signaling pathway
nle04927
Cortisol synthesis and secretion
nle04928
Parathyroid hormone synthesis, secretion and action
nle04934
Cushing syndrome
nle04935
Growth hormone synthesis, secretion and action
nle04970
Salivary secretion
nle04971
Gastric acid secretion
nle04972
Pancreatic secretion
nle04976
Bile secretion
nle05032
Morphine addiction
nle05163
Human cytomegalovirus infection
nle05166
Human T-cell leukemia virus 1 infection
nle05200
Pathways in cancer
nle05207
Chemical carcinogenesis - receptor activation
nle05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100592592 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
100592592 (ADCY8)
04371 Apelin signaling pathway
100592592 (ADCY8)
04020 Calcium signaling pathway
100592592 (ADCY8)
04072 Phospholipase D signaling pathway
100592592 (ADCY8)
04024 cAMP signaling pathway
100592592 (ADCY8)
04022 cGMP-PKG signaling pathway
100592592 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
100592592 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
100592592 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100592592 (ADCY8)
04062 Chemokine signaling pathway
100592592 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
100592592 (ADCY8)
04923 Regulation of lipolysis in adipocytes
100592592 (ADCY8)
04912 GnRH signaling pathway
100592592 (ADCY8)
04913 Ovarian steroidogenesis
100592592 (ADCY8)
04915 Estrogen signaling pathway
100592592 (ADCY8)
04914 Progesterone-mediated oocyte maturation
100592592 (ADCY8)
04921 Oxytocin signaling pathway
100592592 (ADCY8)
04926 Relaxin signaling pathway
100592592 (ADCY8)
04935 Growth hormone synthesis, secretion and action
100592592 (ADCY8)
04918 Thyroid hormone synthesis
100592592 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
100592592 (ADCY8)
04916 Melanogenesis
100592592 (ADCY8)
04925 Aldosterone synthesis and secretion
100592592 (ADCY8)
04927 Cortisol synthesis and secretion
100592592 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100592592 (ADCY8)
04270 Vascular smooth muscle contraction
100592592 (ADCY8)
09154 Digestive system
04970 Salivary secretion
100592592 (ADCY8)
04971 Gastric acid secretion
100592592 (ADCY8)
04972 Pancreatic secretion
100592592 (ADCY8)
04976 Bile secretion
100592592 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
100592592 (ADCY8)
04727 GABAergic synapse
100592592 (ADCY8)
04725 Cholinergic synapse
100592592 (ADCY8)
04720 Long-term potentiation
100592592 (ADCY8)
04723 Retrograde endocannabinoid signaling
100592592 (ADCY8)
09157 Sensory system
04742 Taste transduction
100592592 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
100592592 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
100592592 (ADCY8)
04213 Longevity regulating pathway - multiple species
100592592 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
100592592 (ADCY8)
04714 Thermogenesis
100592592 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100592592 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
100592592 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100592592 (ADCY8)
05163 Human cytomegalovirus infection
100592592 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
100592592 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
100592592 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100592592 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100592592 (ADCY8)
Enzymes [BR:
nle01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
100592592 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
100592592
NCBI-ProteinID:
XP_003256260
Ensembl:
ENSNLEG00000005650
UniProt:
G1R0Z0
LinkDB
All DBs
Position
16:complement(82856139..83127407)
Genome browser
AA seq
1251 aa
AA seq
DB search
MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGS
GSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT
YLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTS
LLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR
LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV
KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH
CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL
ESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPED
IVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV
QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF
IVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINE
TYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG
VLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEA
SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA
RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE
LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKH
SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLIL
KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLV
QSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atggagctctccgatgtgcgctgccttacaggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcaggagcgcctcccggccgcagcggctgctgtggcagacg
gcggtgcgacacatcacggagcagcgcttcattcacgggcaccggggaggcagcggcagc
gggagtggaggctcgggcaaagcctcggaccctgcgggcggcggccccaaccaccacgcg
ccgcagctgtcaggcgactcggcgctgcccctctactcgctgggcccgggggagcgagcg
cacagcacctgcggcaccaaagtcttcccggaacgcagcgggagcggcagtgccagcggc
agcggaggcgggggcgacctgggcttcctgcaccttgactgtgcccctagcaactcggat
ttctttctcaatgggggctatagctaccgaggggtcattttccccaccctgcgcaactcc
ttcaaatctcgggatctggaacgcctctaccagcgctatttcttgggccaaaggcgcaaa
tcggaagtggtgatgaacgtgctggacgtgctgaccaaactcactctcttggtcctacac
ttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttcacc
ggcattgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctcccacacg
tacctgcagtacagcggtgtggtcacctgggtggccatgaccacccagatcctggcagca
ggcctcggctacgggctcctgggcgacggcataggctacgtgctcttcacgctcttcgcc
acctacagtatgctgccgctgccgctcacctgggccatcctggccggcctgggcacctcg
ctgctgcaggtcatcctccaagtggtcatcccccggctggcggtcatttccatcaaccag
gttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagttac
ctatcagatcgggcccaacgccaagctttcctggagactcggaggtgtgtggaggccagg
ctgcgcctggagacagagaaccaaagacaggagcggcttgtgctttctgtgcttccccgg
tttgttgtcctggaaatgatcaacgacatgaccaatgtggaagacgagcacctgcagcac
cagttccatcggatctacatccatcgctatgagaacgtcagtattctttttgcagatgtt
aaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaac
gagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatc
ctaggggactgctactactgcgtgtctggacttcctgagccccgccaggaccatgcccat
tgctgtgttgaaatgggtctcagcatgataaaaaccatcaggtatgtgcggtcaaggaca
aaacacgatgttgacatgaggattggaatccactcaggctcggtactgtgcggtgttttg
ggactaaggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaacaaactc
gaatctggaggaatccccgggaggattcacatttccaaagccacactggactgtctcaac
ggtgactataacgtggaagagggtcatggtaaagagaggaatgaattcctgaggaagcat
aatatcgagacttacttaattaagcagcctgaggacagtctgctgtccttgcctgaagat
atcgtcaaggagtcagtgagctcctcagaccggagaaacagtggggccacattcactgaa
ggatcctggagccctgaactgccctttgataacatcgtggggaaacagaatactctggct
gccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtc
cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc
gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg
gagcacaagtattctcaaatgagggatgaagtgttcaagtcaaacttggtctgtgcattt
atcgttcttctatttatcacggcaatacaaagtttgcttccttcttcaagagtgatgcca
atgaccatccagttctccattctgattatgctgcactcggctctggtcctcatcaccaca
gcagaggattataagtgtttgcccctcatccttcggaaaacttgctgttggattaatgag
acctatttggcccggaacgtcatcatctttgcatccatcttgattaatttcctgggtgcc
atcttaaatatcttgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc
aattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacgggg
gtgttggccatggtgacctgtgcagttttcctccggctgaactccgtcctgaagctggca
gtgctgctgatcatgatcgccatctatgccctgctcactgagaccgtctacgcaggcctc
tttctgcgttatgacaacctcaaccacagtggagaagatttcctggggaccaaggaggca
tcgctgctactgatggccatgttcctcctggctgtgttctaccatggacagcagctggag
tacacagcccgcctggacttcctttggcgagtacaggccaaagaggagatcaatgagatg
aaggagctgagggaacacaatgagaacatgctccggaatatcttacccagccacgtggcc
cgccatttcctagagaaggaccgagacaatgaggagctgtattctcaatcctatgatgct
gttggggtgatgtttgcctccatcccaggatttgcggacttttactctcagaccgaaatg
aataaccagggagtggaatgcctgcgcttgctgaatgagatcattgctgacttcgatgag
ttgcttggtgaagaccgatttcaagacattgaaaagattaagaccattggcagcacctac
atggccgtgtcaggcctgtcacctgaaaaacagcaatgtgaagacaagtggggacatttg
tgtgctctggctgacttctcacttgccctgacagaaagcatacaggagatcaacaagcat
tcattcaacaattttgaactccggattggcatcagccacggttcagtggtagctggcgtt
atcggcgctaagaaaccacagtatgacatttggggcaaaactgtgaacctggcaagccga
atggacagcacgggggttagtggccggatccaagtcccagaggagacctatctcatcctg
aaggaccagggctttgcctttgattaccgaggggagatctatgtgaagggcatcagtgaa
caggaaggaaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatc
ttgcccccaagaagactgcctgggcagtactccctggccgcggttgtcctgggacttgtc
cagtccctcaataggcaaaggcagaagcagctactcaacgagaacaacaacacaggaatc
atcaagggtcattataaccggcggactttgttgtcacccagcgggacggagcctggagcc
caagctgaaggcactgacaaatctgatttgccataa
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integrated database retrieval system
