Nomascus leucogenys (northern white-cheeked gibbon): 100593459
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Entry
100593459 CDS
T03265
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00020
Citrate cycle (TCA cycle)
nle00480
Glutathione metabolism
nle01100
Metabolic pathways
nle01200
Carbon metabolism
nle01210
2-Oxocarboxylic acid metabolism
nle01230
Biosynthesis of amino acids
nle04146
Peroxisome
nle05230
Central carbon metabolism in cancer
Module
nle_M00009
Citrate cycle (TCA cycle, Krebs cycle)
nle_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100593459 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100593459 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100593459 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100593459 (IDH2)
Enzymes [BR:
nle01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
100593459 (IDH2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
100593459
NCBI-ProteinID:
XP_003268543
Ensembl:
ENSNLEG00000011819
UniProt:
G1RMM2
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All DBs
Position
6:complement(108843870..108862116)
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AA seq
452 aa
AA seq
DB search
MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQELIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTTDFLDTIKSNVDRALGRQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgggtcgtgcgctcgctctgcagagcctcaggctcgcggccggcc
tgggcgccggcggccctgacggcccccacctcgcaagagcagccgcggcgccactatgcc
gacaaaaggatcaaggtggcgaagcccgtggtggagatggatggtgatgagatgacccgt
attatctggcagttcatcaaggagaagctcatcctgccccacgtggacatccagctaaag
tattttgacctcgggctcccaaaccgtgaccagaccgatgaccaggtcaccattgactct
gcactggccacccagaagtacagtgtggctgtcaagtgtgccaccatcacccctgatgag
gcccgtgtggaagagttcaagctgaagaagatgtggaaaagtcccaatggaactatccgg
aacatcctgggggggactgtcttccgggagcccatcatctgcaaaaacatcccacgccta
gtccctggctggaccaagcccatcaccattggcaggcatgcccatggcgaccagtacaag
gccacagactttgtggcagaccgggccggcacgttcaaaatggtcttcaccccaaaagat
ggcagcggtgtcaaggagtgggaagtgtacaacttccccgcaggcggcgtgggcatgggc
atgtacaacaccgacgagtccatctcgggttttgcgcacagctgcttccagtatgccatc
cagaagaaatggccgctgtacatgagcaccaagaacaccatactgaaagcctacgatggg
cgtttcaaggacatcttccaggagatctttgacaagcactataagaccgacttcgacaag
aataagatctggtatgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcgggcggctttgtgtgggcctgcaagaactatgacggagatgtgcagtcagacatcctg
gcccagggctttggctcccttggcctgatgacgtccgtcctggtctgccctgatgggaag
acgattgaggctgaggccgctcatgggaccgtcacccgccactatcgggagcaccagaag
ggccggcccaccagcaccaaccccatcgccagtatctttgcctggacacgtggcctggag
caccgggggaagctagatgggaaccaagagctcatcaggtttgcccagacgctggagaag
gtgtgcgtggagacggtggagagtggagccatgaccaaggacctggcgggctgcattcac
ggcctcagcaatgtgaagctgaacgagcacttcctgaacaccacagacttcctcgacacc
atcaagagcaacgtggacagagccctgggcaggcagtag
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