Nyctereutes procyonoides (raccoon dog): 129497055 Help Entry 129497055         CDS       T09008                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo01521   EGFR tyrosine kinase inhibitor resistance npo04151   PI3K-Akt signaling pathway npo04217   Necroptosis npo04380   Osteoclast differentiation npo04550   Signaling pathways regulating pluripotency of stem cells npo04620   Toll-like receptor signaling pathway npo04621   NOD-like receptor signaling pathway npo04630   JAK-STAT signaling pathway npo04658   Th1 and Th2 cell differentiation npo04659   Th17 cell differentiation npo05140   Leishmaniasis npo05145   Toxoplasmosis npo05152   Tuberculosis npo05160   Hepatitis C npo05161   Hepatitis B npo05162   Measles npo05163   Human cytomegalovirus infection npo05164   Influenza A npo05165   Human papillomavirus infection npo05166   Human T-cell leukemia virus 1 infection npo05167   Kaposi sarcoma-associated herpesvirus infection npo05168   Herpes simplex virus 1 infection npo05169   Epstein-Barr virus infection npo05171   Coronavirus disease - COVID-19 npo05200   Pathways in cancer npo05203   Viral carcinogenesis npo05212   Pancreatic cancer npo05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:npo00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     129497055 (JAK1)    04151 PI3K-Akt signaling pathway     129497055 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     129497055 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     129497055 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     129497055 (JAK1)    04621 NOD-like receptor signaling pathway     129497055 (JAK1)    04658 Th1 and Th2 cell differentiation     129497055 (JAK1)    04659 Th17 cell differentiation     129497055 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     129497055 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129497055 (JAK1)    05203 Viral carcinogenesis     129497055 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     129497055 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     129497055 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129497055 (JAK1)    05161 Hepatitis B     129497055 (JAK1)    05160 Hepatitis C     129497055 (JAK1)    05171 Coronavirus disease - COVID-19     129497055 (JAK1)    05164 Influenza A     129497055 (JAK1)    05162 Measles     129497055 (JAK1)    05168 Herpes simplex virus 1 infection     129497055 (JAK1)    05163 Human cytomegalovirus infection     129497055 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     129497055 (JAK1)    05169 Epstein-Barr virus infection     129497055 (JAK1)    05165 Human papillomavirus infection     129497055 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     129497055 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     129497055 (JAK1)    05140 Leishmaniasis     129497055 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     129497055 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:npo01001]     129497055 (JAK1) Enzymes [BR:npo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      129497055 (JAK1) Protein kinases [BR:npo01001]  Non-receptor tyrosine kinases   JAK family [OT]    129497055 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  129497055 NCBI-ProteinID:  XP_055161485 LinkDB All DBs Position Unknown AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEMLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSEFGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPHCPEEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaatctggaggcccctgaaccaggggtggaagtgctgttc tatctttctgatagggagcccctccggctgggcagcggagagtacacagcagaggagcta tgcatcagggccgcgcaggaatgctgtatctctccactttgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccgttgatgacaag acatcgctccggctccactaccggatgaggttctatttcaccaactggcatgggactaat gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaagttccagatgctacccctcttcttgatgccagttctttggagtatctctttgct cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagactgagcag gatgggcacgatattgagaatgagtgtctgggaatggctgtcctggccatctcccactat gccatgatgaagaagatgcagttaccagaactgcccaaggacatcagctataagcgatat attccagagacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctgaaggaatttaataacaagactatttgtgacagtagt gtatctactcatgacctaaaggtgaaatatctggctaccttggaaactttgacaaagcat tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcatccgaacgacagtggaaacattctctactatgaagtgatggtaactggaaat cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggacgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttacttccctgaaatcacacacattgtaataaaggagtct gttgtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcatcccatgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagatgcccat cattacctctgcactgatgtggctcccccattgatcgtccacaacatacagaatggttgt cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag gggatgtatgtgctgaggtggagctgtaccgacttcgacaatattctcatgactgtcacc tgctttgaaaaatctgagatgctgggtggccagaaacagttcaagaattttcagattgag gtgcagaagggccgctatagcctgcacggctcagatcgcagcttccccagcctaggggac ctgatgagccacctcaagaagcagatcctgcgtacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagcc caagagtggcagccagtctaccccatgagccagctgagttttgaccggatcctcaagaag gatattgtgcaaggcgagcaccttgggagaggcacacggacacacatctactccggtact ctggtggattataaggatgatgaaggaacctctgaagaaaagagaataaaagtcatcctc aaagtcttagaccccagccacagggacatttctctggctttctttgaggcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctacggcgtctgtgtccgagatgtg gagaatatcatggtggaagagtttgtggagggggggcctctagatctcttcatgcaccgg aaaagtgatgtcctcaccacaccatggaagttcaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagacctagttcatggaaatgtgtgcactaaaaaccttctc ctggcccgtgagggcattgacagcgagttcggcccgttcatcaagctcagtgaccctggc atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctcct gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acattgtgggaaatctgctacaatggcgagatccctctgaaagacaagaccctgattgag aaagagagattctatgaaagccggtgccggccagtgacaccatcctgtaaggagctggct gaccttatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc atgagagacatcaataaactggaagagcagaatccagacattgtttccgaaagaaagccg gcaactgaagtggatcccacacattttgaaaaacggttcttgaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggataatact ggggagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat ctgaagaaggaaatcgaaattctaaggaacctttatcatgagaacattgtgaagtacaaa ggcatctgtacagaagacggaggaaatggtattaagctcatcatggaatttctgccttca ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagtta aaatatgccgttcagatttgtaaggggatggactatttaggttctcggcaatatgttcac cgggacttagcagcaaggaatgtccttgttgagagtgaacaccaagtgaaaattggagac tttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaaggatgatcgg gacagccctgtgttttggtatgctcctgaatgtttaattcaatgtaaattttatatcgcc tctgatgtctggtcgtttggagtgaccctgcatgagttgcttacttactgtgactcagat tccagccccatggcgttgtttctgaaaatgataggcccaactcatggccagatgacagta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctcactgtcca gaagaggtttatcaacttatgagaaaatgctgggaattccagccatctaatcggacaact tttcagaaccttattgaaggatttgaagcacttttaaaataa

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