Neomonachus schauinslandi (Hawaiian monk seal): 110580916
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Entry
110580916 CDS
T08474
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00230
Purine metabolism
nsu01100
Metabolic pathways
nsu04022
cGMP-PKG signaling pathway
nsu04024
cAMP signaling pathway
nsu04924
Renin secretion
nsu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110580916 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
110580916 (PDE3A)
04022 cGMP-PKG signaling pathway
110580916 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
110580916 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110580916 (PDE3A)
Enzymes [BR:
nsu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
110580916 (PDE3A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
TgpA_N
Motif
Other DBs
NCBI-GeneID:
110580916
NCBI-ProteinID:
XP_021546283
EnsemblRapid:
ENSNSCG00000016165
UniProt:
A0A2Y9H3S9
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Position
5:complement(84738683..85058905)
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AA seq
1142 aa
AA seq
DB search
MAVPREAARVGDKPGHGGVYPAPAAGPDCPAGAGPAQSRDSGSHGRWGDLVLQPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEIGRDLEQSKEVAAAAAEEEAAPGAEGGVFPGLRGGA
PGGGAPLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLG
VGEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPY
LAYLAGVLGLLLARYVEQILPQSAGAAPREHFGSQQIAGTKEDIPVFKRRRRSSSVVSAE
MSGCSSKSHRRTSLPCIPREQLMGHAEWDHKRGARGSQSSGTSITVDIAVMGEAHGLITD
LLADPSLPPNVCTSLRAVSNLLNTQLTFQAIHKPRMNPVVSFSENYTCSDSEESSEKDKL
AIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEASSSSPDSW
NNPVMMTLTKSRSFTSSYAVSAANHVNSKKPNRPGALAKISPLSSPCSSPPQGTPANSPV
SKISAVRFPESANTTARQGLGSHRALTYTQSAPDLSPQTLPPPVICSSCGRPYPQGNPAD
GPLEGSSAAIRTPSRMDDTTQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASGCGPY
TPEAMIFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYRLF
EDMGLFEAFKIPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGHSTVI
NDHGSASDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYD
HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRF
LVIEAILATDLKKHFDFVARFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKE
LHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSA
GLMPGKWVEGSDESGDTDDPEEEEEEEEAPNEEETCENNESPRKKTFKRRKIYCQITQHL
LQNHKMWKKVIEEEQRLAGLENPSLDPSPQQHSSDQIQAIREEEEEKGKPRGEEIPTAEQ
NQ
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgccccgcgaggccgcgcgagtcggggacaagcccggccacggtggggtgtat
ccagcccccgcggcgggcccggactgtcccgctggcgccggccccgcacagtcgcgggac
tccggcagccacggccgttggggagacctggtgctgcagccgctccggcgctcccggaaa
ctttcctcagcgctgtgcgcgggctccctgtcctttctgctggccctgctggtgaggctg
gtgcgcggggagatcggccgcgacctggagcagagtaaggaggtggcggcggcggcggcg
gaggaggaagcggccccgggagcagaagggggcgtcttcccggggcttcggggaggtgct
cctgggggcggcgcgccgctcagcccctggctgcagccctcggcgctgctcttcagtctt
ctgtgtgccttcttctggatgggcttgtacctcctgcgcgccggggtgcgcctgcctctg
gccgtcgcactgctcgccgcctgctgcgggggggaagcgctcgtccagattgggctgggc
gtcggggaggatcacttactctcgctcccggccgcgggggtggtgctcagctgcttggcc
gccgcgacatggctggtgctgaggctgaggctgggcgtcctcatgatcgccttgactagc
gcggtcaggaccgtgtccctcatttccttagagaggttcaaggtcgcctggagaccttac
ctggcgtacttggccggcgtgctggggctcctcctggccaggtacgtggagcaaatcttg
ccgcagtccgcgggggcggctccgagggagcacttcgggtcccagcaaattgctgggacc
aaggaagatatcccagtatttaagaggaggaggcggtccagctccgtggtgtccgcggag
atgtccggctgcagcagcaagtcccatcggaggacctccctgccctgcataccgagggaa
cagctcatggggcatgcagaatgggaccacaaacgaggggcaagaggatcacagtcctca
ggaaccagtattactgtggatattgccgtgatgggtgaggctcatggcctcattaccgac
ctcctggcagacccttcactgccccccaacgtgtgcacatccttgagggcagtgagcaac
ctgctcaacacccagctcaccttccaggctattcacaagccccgcatgaatcctgttgtt
tccttcagtgaaaattacacctgttctgattctgaggaaagctctgaaaaagacaagctg
gctattcccaagcgcctgagaaggagtttgcctcctggtttgttgagacgggtttcatca
acttggacaaccaccacctcagccacaggcctacccactttggagcctgccccagtacgg
agggaccggagcgctagcatcaaactgcatgaagcatcttcatcaagtcctgattcttgg
aataacccagtgatgatgaccctcaccaaaagcagatccttcacttcatcctatgctgtt
tctgcagctaaccatgtaaactcaaaaaagccaaatcgaccaggtgccctagctaaaatt
tcacctctttcatcgccctgttcctcacccccccaagggactcctgccaacagcccagtc
agcaaaatttctgcagtgcggtttccagaatctgccaacacgactgccagacaaggccta
ggttctcacagggcattaacttatactcagagtgcccctgacctgtctcctcagaccctc
cctccacctgttatatgtagcagctgtggcagaccatatcctcaagggaatcctgctgat
gggcccctggagggaagcagtgcagccattcggacaccaagcagaatggatgacactact
caagttacctctgattatgaaaccaacaacaacagtgatagcagtgatattgtacagaac
gaagatgagactgagtgcctgagggagcctctaaggaaagcttctggttgtggcccctac
acgcctgaggccatgatattcctggacaagccaattcttgctcctgaacctcttgtcatg
gataacttggactcaattatggagcagctaaatacttggaattttccaatttttgatttg
gtggaaaaaataggaagaaaatgtggccgtatccttagtcaggtatcatacagacttttt
gaagacatgggcctctttgaagctttcaaaattccagttagggaatttatgaattatttt
catgctttggagattggatacagggaaattccttatcataacagaatccacgccactgat
gtgttacacgctgtgtggtaccttactacgcaaccgattccgggccactcaactgtgatt
aatgatcacggatccgcaagtgattcagattctgacagtggatttacacatggacatatg
ggatatgtcttctcaaaaatgtataatgtgcctgatgataaatacggatgtctatctgga
aatatccctgccttagagttaatggcattgtatgtggctgcagccatgcatgattatgat
cacccaggaaggactaacgctttcttggtggcaactagtgctcctcaggcggtgctctat
aatgatcgttcagttttggagaatcatcatgcagctgctgcatggaatcttttcatgtcc
cggccagagtacaacttcttagttaaccttgaccatgtggaatttaagcattttcgtttc
cttgtcattgaagcaattttggccactgacctgaagaaacactttgatttcgtagccaga
tttaatgccaaggtgaatgatgatgttggaatagattggaccaatgaaaatgatcgccta
ctggtttgccaaatgtgtataaagttggctgatatcaatgggccagctaagtgtaaagag
ctccatcttcagtggacagagggtattgtcaatgaattttatgaacagggtgatgaagag
gccagccttgggttaccaataagccccttcatggaccgttctgctcctcagctggccaat
cttcaggaatccttcatctctcacattgtgggtcctctgtgcaactcctatgattcagca
ggactaatgccagggaaatgggtggaaggtagtgatgagtcaggagatactgatgaccca
gaagaagaagaagaggaggaggaagcaccaaatgaagaggaaacctgtgaaaataatgaa
tctccaagaaagaaaactttcaaaaggaggaaaatctactgccaaataactcagcacctc
ctgcagaaccacaagatgtggaagaaagtcattgaagaggaacagcggttggcgggccta
gagaatccgtccctggacccatccccccagcagcattcctcagatcagatccaggccatc
agggaagaggaggaagagaaagggaagcccagaggagaggagatcccgaccgccgagcaa
aaccagtga
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