Ovis aries (sheep): 101115878
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Entry
101115878 CDS
T03117
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X2
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00564
Glycerophospholipid metabolism
oas00565
Ether lipid metabolism
oas00590
Arachidonic acid metabolism
oas00591
Linoleic acid metabolism
oas00592
alpha-Linolenic acid metabolism
oas01100
Metabolic pathways
oas04010
MAPK signaling pathway
oas04014
Ras signaling pathway
oas04072
Phospholipase D signaling pathway
oas04217
Necroptosis
oas04270
Vascular smooth muscle contraction
oas04370
VEGF signaling pathway
oas04611
Platelet activation
oas04664
Fc epsilon RI signaling pathway
oas04666
Fc gamma R-mediated phagocytosis
oas04724
Glutamatergic synapse
oas04726
Serotonergic synapse
oas04730
Long-term depression
oas04750
Inflammatory mediator regulation of TRP channels
oas04912
GnRH signaling pathway
oas04913
Ovarian steroidogenesis
oas04921
Oxytocin signaling pathway
oas05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
101115878 (PLA2G4E)
00565 Ether lipid metabolism
101115878 (PLA2G4E)
00590 Arachidonic acid metabolism
101115878 (PLA2G4E)
00591 Linoleic acid metabolism
101115878 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
101115878 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101115878 (PLA2G4E)
04014 Ras signaling pathway
101115878 (PLA2G4E)
04370 VEGF signaling pathway
101115878 (PLA2G4E)
04072 Phospholipase D signaling pathway
101115878 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101115878 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101115878 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
101115878 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
101115878 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
101115878 (PLA2G4E)
04913 Ovarian steroidogenesis
101115878 (PLA2G4E)
04921 Oxytocin signaling pathway
101115878 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101115878 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
101115878 (PLA2G4E)
04726 Serotonergic synapse
101115878 (PLA2G4E)
04730 Long-term depression
101115878 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101115878 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
101115878 (PLA2G4E)
Enzymes [BR:
oas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
101115878 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
101115878
NCBI-ProteinID:
XP_012036651
EnsemblRapid:
ENSOARG00020014596
LinkDB
All DBs
Position
7:complement(35602572..35681493)
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AA seq
832 aa
AA seq
DB search
MMLQKQMPVWVSHYPPDSCQEDGDRPTATCALEEGLSPCHLLTVRVIRMKNVRQADVVSL
TDCFVSLWLPTASQKRLRTRTISNCRNPEWNETFSFQIQSQVKNVLELSVCDEDTVTPDD
HLLTVLYDLTKLCFRKKTHVKFPLNTEGMEELEVEFLLEESPSPPENLITNGVLVSRQMS
CLEVCAESRRPKKRKKKDLLVTVTESFEHTQRVSPCLESCCSNPACFQYPKYFQPEVHVE
LPKSPWICELCCCAGQKGPVCQSLHCLPDGQAVTLPVNENCELHMKSTPCSQVLDVRLGF
SLCQAELEFLQKRRVVVAQALKEVLQLEEDLRADEVPLIAIMATGGGTRSMTAMYGHLLA
LQKLNILNCASYITGLSGATWTMATLYRDPDWSSKSLERAILEARRHVVKDKMPALFPDQ
LLKFQEELQQRRQEGYKVTFTDFWGLLIEACLGDERNECKLSDQRAALCQGQNPLPIYLT
INVKDDVSNQDFREWFEFSPYEVGMQKYGAFIPTELFGSEFFMGRLRKRIPESRMCYMLG
LWSSIFSLNLLDAWNLSHTSEEFFHQWTRDRVHDIEDEPLLPEIPKCDANVLDTTVVTPA
SWLSNTFRDILTHRAFVSKFHNFLLGLQLHTDYLQNSQFSMWKDTVLDGFPNQLTGSVKH
LCLLDTAFFVNSSYAPLLRPERKADLIIHLNYCAGSQTKPMKQTCEYCAMQNIPFLKYEL
QKEEDNLKECYLLENAQEPDTPIVTFFPLICDTFQNYKAPGVERSPEELEQGQVDIYGPK
TPYATKELTYTEAAFDKLVKLSEYNILNNKDKLLQALRLAVERKRQKSPCPL
NT seq
2499 nt
NT seq
+upstream
nt +downstream
nt
atgatgctccagaagcagatgcctgtgtgggtctcccactacccgccagactcatgccaa
gaggatggggacaggcccacggccacctgtgcattggaggaggggctgtctccatgccac
ctgctgacagtgagggtcatccgcatgaagaacgtccgacaggctgacgtggtgagccta
acagactgctttgtgagcctctggctgcccactgccagtcaaaagaggctgaggactagg
accatctccaactgccgaaacccagaatggaatgaaaccttcagcttccagatccagagc
caagtgaagaatgttctggagctgagcgtctgtgatgaagacacagtgacacctgatgac
catctcttgacagttctctatgacctcaccaagctctgcttccgaaagaaaacccacgtg
aagttcccactcaacacagagggcatggaggagctggaagtggagttcctgctggaggag
agcccctctccacctgagaacctcatcacgaacggcgtgctggtgtctcgacaaatgtcc
tgcctggaggtttgtgcagaatccaggaggccaaagaagaggaaaaagaaggacctcctg
gtgacagtgacggagtccttcgagcacacccagcgcgtctcaccctgcctggagtcctgc
tgctcaaaccctgcctgcttccaataccccaaatacttccagcccgaggtgcacgtggag
ttgcccaagagcccgtggatctgtgagctttgctgctgtgcgggccagaagggccctgtg
tgccagtccctccattgcctccccgacggccaggcggtgaccttgcctgtgaatgagaac
tgtgaattacacatgaagtctacaccctgttcccaggtgttggacgtgcggctgggcttc
agcctgtgccaggcagaactggagttcctgcagaaacggagggtggtggtggcccaggcg
ctgaaggaggtgctgcagctggaggaagacctgcgggcagatgaggtcccgctgatagcc
atcatggccactggaggtggaacaagatctatgaccgccatgtatggccacctgctggca
ctgcagaagctgaacatcctgaactgtgccagctatatcaccggcctgtctggggccacc
tggaccatggccaccttgtatcgtgaccctgactggtcctccaaaagcctggagcgcgcc
atcctcgaggcacggaggcacgtggtcaaggacaagatgcctgccctgtttccagaccag
ctcctcaaattccaggaggagctccagcagcgcaggcaggaaggctacaaggtcaccttc
acagacttctggggcctgctgattgaggcctgtctgggggatgagagaaatgaatgcaaa
ctgtcagatcagcgtgctgctttgtgccagggccagaaccccctgcccatctacctcacc
atcaatgtcaaggatgatgtaagcaaccaggatttcagagagtggttcgagttctccccc
tacgaggtgggcatgcagaagtatggagccttcatccccacagagctcttcggctccgag
ttcttcatggggcggctgaggaagagaatcccagagtcgcggatgtgctacatgctaggt
ttgtggagtagcatcttctccctgaacctgcttgacgcctggaacctatcccacacctcg
gaggagtttttccaccagtggacaagggatagagtgcatgatattgaagacgagccactc
ctgcctgaaatccccaaatgtgatgccaacgtcctggacaccacagtggtgacaccagca
tcctggctgtccaacactttccgcgacatcctcacccacagggcctttgtctccaagttc
cacaatttcctgctggggctgcagctgcacactgactacctccagaacagccagttctcc
atgtggaaagacacggtgctggacggcttcccaaaccagctgacaggatctgtgaaacac
ttgtgcctgttggacaccgcattctttgtcaactccagctacgcgcccctcctcaggccc
gagagaaaagctgacctcatcatccaccttaattactgtgctggctcccagacaaagccc
atgaagcaaacctgcgagtactgcgccatgcagaacatccccttcctcaaatacgagctg
caaaaggaggaggataacctcaaggagtgctacctgctggagaacgcccaggagcccgac
acccccatcgtgacctttttcccactcatctgcgacaccttccaaaattacaaggcccca
ggtgtggaacgaagccctgaggagctggagcagggccaggttgacatctacggtcccaaa
actccctacgccaccaaggagctgacatacactgaggccgccttcgacaagctggtgaag
ctttccgagtataacatcctgaataacaaggacaagctccttcaggccttgcgactggca
gtagagaggaaacgccagaagagcccgtgtcccctctaa
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