KEGG   Ovis aries (sheep): 101116344
Entry
101116344         CDS       T03117                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X2
  KO
K10140  DNA damage-binding protein 2
Organism
oas  Ovis aries (sheep)
Pathway
oas03420  Nucleotide excision repair
oas04115  p53 signaling pathway
oas04120  Ubiquitin mediated proteolysis
oas05161  Hepatitis B
oas05169  Epstein-Barr virus infection
oas05200  Pathways in cancer
oas05202  Transcriptional misregulation in cancer
oas05210  Colorectal cancer
oas05212  Pancreatic cancer
oas05213  Endometrial cancer
oas05214  Glioma
oas05216  Thyroid cancer
oas05217  Basal cell carcinoma
oas05218  Melanoma
oas05220  Chronic myeloid leukemia
oas05222  Small cell lung cancer
oas05223  Non-small cell lung cancer
oas05224  Breast cancer
oas05225  Hepatocellular carcinoma
oas05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oas00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101116344 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    101116344 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    101116344 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101116344 (DDB2)
   05202 Transcriptional misregulation in cancer
    101116344 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101116344 (DDB2)
   05212 Pancreatic cancer
    101116344 (DDB2)
   05225 Hepatocellular carcinoma
    101116344 (DDB2)
   05226 Gastric cancer
    101116344 (DDB2)
   05214 Glioma
    101116344 (DDB2)
   05216 Thyroid cancer
    101116344 (DDB2)
   05220 Chronic myeloid leukemia
    101116344 (DDB2)
   05217 Basal cell carcinoma
    101116344 (DDB2)
   05218 Melanoma
    101116344 (DDB2)
   05213 Endometrial cancer
    101116344 (DDB2)
   05224 Breast cancer
    101116344 (DDB2)
   05222 Small cell lung cancer
    101116344 (DDB2)
   05223 Non-small cell lung cancer
    101116344 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101116344 (DDB2)
   05169 Epstein-Barr virus infection
    101116344 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:oas04121]
    101116344 (DDB2)
   03400 DNA repair and recombination proteins [BR:oas03400]
    101116344 (DDB2)
Ubiquitin system [BR:oas04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     101116344 (DDB2)
DNA repair and recombination proteins [BR:oas03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      101116344 (DDB2)
SSDB
Motif
Pfam: WD40 NBCH_WD40
Other DBs
NCBI-GeneID: 101116344
NCBI-ProteinID: XP_004016496
EnsemblRapid: ENSOARG00020010497
UniProt: W5P607
LinkDB
Position
15:76026389..76045000
AA seq 427 aa
MAPRKRPEAQKTPEVVVRPKSKRNRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
RVPPLCSSIVRALHQHKLGTAAWPSLQQGLQQSFLNSLASYRIFQKAAPFDRRATSLAWH
PTHPSTLAVGSKGGDILLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFFTSSMEGT
TRLQDFKGNTLRVFASSDTCNVWFCSLDISVKSRVVVTGDNVGHVILLNMDGRELWNLRM
HKKKVTHVALNPCCDWLLATASVDQTVKIWDLRQVRGKSSFLHSLPHRHPVNAAHFSPDG
AQLLTTDQKSEIRVYSACQWDCPPSLIPHPHRHFQHLTPIKASWHPRYNLIVVGRYPDPN
FKSCSPHELRTIDVFDGSSGKIMYQLYDPESSGIMSLNEFNPMGDTLASVMGYHILVWSP
EDAGTQK
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggctcccaggaaacgcccagaagcccagaagacccctgaggtggttgtgcgccccaag
agcaagaggaacagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggctgcctttgggcggggttggctagcctg
cgggtcccgccgctatgcagcagcatcgtcagggccctccaccagcataagctgggcaca
gctgcctggccatcactacagcagggtctccagcagtcctttttgaactctctggcttct
taccggattttccaaaaggctgccccttttgacaggagggccacatccctggcgtggcac
ccaactcaccccagcaccctggctgtgggctccaaagggggagatatcttgctctggaac
tttggcataaaggacaaacctaccttcattaaagggattggagctggagggagcatcact
gggctgaagtttaaccctctcaataccaaccagtttttcacctcctcaatggagggaacg
actaggctgcaagactttaaaggcaacactctccgagtttttgccagctcagacacctgc
aacgtctggttctgcagcctggatatatctgtcaaaagccgagtggtggtcacgggagac
aacgtggggcacgtgatcctgctgaacatggacggcagggagctctggaatctgagaatg
cacaaaaagaaggtgacccatgtggccctgaacccgtgctgtgactggctcctggccaca
gcctccgtagatcaaacggtgaaaatctgggacctgcgccaggttagagggaaatccagc
ttcctccactcgctgccgcacaggcatcctgtcaacgcagctcatttcagtcccgatgga
gcccagctcctgaccactgaccagaagagtgagatccgggtttactctgcttgccagtgg
gactgcccgccaagcctgatcccacatcctcaccgccacttccagcacctgacgcccatc
aaggcaagctggcatcctcggtacaacctcattgtcgtgggccgatacccagatcctaat
ttcaaaagttgttccccccatgaattaaggacgatcgatgtgtttgatggaagctcagga
aagatcatgtatcagctgtatgacccagaatcttctggtatcatgtcgctcaatgaattc
aatcccatgggggacacgctggcctctgtgatgggttatcacattcttgtttggagcccg
gaggatgctgggactcagaaatga

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