Oryctolagus cuniculus (rabbit): 100328584
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Entry
100328584 CDS
T03373
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00020
Citrate cycle (TCA cycle)
ocu00190
Oxidative phosphorylation
ocu01100
Metabolic pathways
ocu01200
Carbon metabolism
ocu04714
Thermogenesis
ocu04932
Non-alcoholic fatty liver disease
ocu05010
Alzheimer disease
ocu05012
Parkinson disease
ocu05014
Amyotrophic lateral sclerosis
ocu05016
Huntington disease
ocu05020
Prion disease
ocu05022
Pathways of neurodegeneration - multiple diseases
ocu05208
Chemical carcinogenesis - reactive oxygen species
ocu05415
Diabetic cardiomyopathy
Module
ocu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ocu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
ocu_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100328584 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
100328584 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
100328584 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100328584 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
100328584 (SDHA)
05012 Parkinson disease
100328584 (SDHA)
05014 Amyotrophic lateral sclerosis
100328584 (SDHA)
05016 Huntington disease
100328584 (SDHA)
05020 Prion disease
100328584 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
100328584 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100328584 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100328584 (SDHA)
Enzymes [BR:
ocu01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
100328584 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
100328584
NCBI-ProteinID:
XP_017194705
LinkDB
All DBs
Position
Unknown
AA seq
665 aa
AA seq
DB search
MAGVRVVSRLLLARRLALTRAQRPAALQTGTRDFHFTVDGHTRASAKVSDSISAQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACITKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCI
EDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKI
SQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKV
RIDEYDYSKPIQGQQKKPFGEHWRKHTLSYVDVKTGKVTLEYRPVIDKTLNEADCATVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atggctggggtccgagtggtgtcgcggctgctgttggcgcggcgtttggcgctgacccgg
gcgcagcggccggcagcactgcagacaggaacccgtgattttcacttcactgttgatggc
catacaagggcatctgccaaagtctcagattctatttctgctcagtacccagtagtggac
catgaatttgatgcagtggtggtcggtgctggtggagctggcttacgagctgcatttggc
ctctcggaggcaggatttaacacagcatgcatcacaaagctctttcctaccaggtcacac
actgtggcggcacagggaggcatcaatgctgctctgggaaatatggaagaagacaattgg
agatggcatttctacgacaccgtgaagggctctgactggctgggggaccaggacgccatc
cactacatgacagagcaagcccctgcctctgtggtcgagctagaaaattatggcatgcca
tttagcagaactgaagacgggaggatctatcagcgtgcgttcggtggacagagcctcaag
tttgggaaaggcgggcaggcccaccgatgctgctgtgtggctgatcggaccggccactca
ctcctgcacaccttgtatggaaggtctctgcgatatgataccagctattttgtggagtac
tttgccttggatcttctgatggagaatggggagtgtcgtggtgttatcgcgctgtgcata
gaagatgggtccatccaccgcatacgagcaaagaacactgttgttgcgaccggaggctat
gggcgcacttacttcagctgcacgtctgcccacaccagcaccggtgatgggacagccatg
gtcaccagggccggccttccttgccaggacttggagttcgtccagttccaccccacaggc
atatatggtgctggttgtctcattacagaagggtgccgtggagagggaggcattctcatt
aacagtcagggcgaaaggttcatggagagatacgcccctgtcgcgaaggacctggcttcc
agagatgtggtgtctcggtcaatgaccctggagatccgagaaggaagaggctgtggcccc
gagaaggatcatgtctacctgcagctgcaccatctgccacccgagcagctggccacacgc
ctgcctggcatttctgagacggccatgatcttcgcgggtgtggacgtcaccaaggagcca
atccctgtgctccccacggtgcactataacatgggcggcattcctaccaactacaaggga
caggttctgaggcacgtgaatggccaggatcagattgtgcccggcctgtatgcctgtggg
gaggctgcctgtgcctcggtacacggtgccaaccggctcggggcaaactcgctgctggac
ttggtggtctttggccgggcctgtgccctgagcattgcagagtcctgcagacccggagat
aaagtccccccgattaaaccaaatgcaggggaagagtctgttatgaatcttgacaagttg
agatttgctgatgggagcatcaggacgtcggagctgcgcctcagcatgcagaagtctatg
cagagtcatgctgcagtgttccgtgttgggagcgtgttgcaggaaggctgtgagaagatc
agccagctctacggagacctgaagcacctgaagacgtttgacagggggatggtctggaat
acagacttggtggagaccctggagctgcaaaatctgatgctgtgtgcgctgcagaccatc
tacggagctgaggctcggaaggagtctcggggtgcccacgccagggaggattacaaggtg
cggatcgatgagtacgattactccaagcctattcaagggcagcagaagaagccgtttggg
gagcactggaggaagcacaccctttcttacgttgatgtcaagactgggaaggtcactctg
gagtacagacctgtaattgacaaaaccttgaacgaagctgactgcgccacagtgccccct
gccatccgctcctactga
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