Otolemur garnettii (small-eared galago): 100964845 Help Entry 100964845         CDS       T07855                                  Symbol ROCK1 Name (RefSeq) rho-associated protein kinase 1   KO K04514   Rho-associated protein kinase 1 [EC:2.7.11.1] Organism oga  Otolemur garnettii (small-eared galago) Pathway oga04022   cGMP-PKG signaling pathway oga04024   cAMP signaling pathway oga04062   Chemokine signaling pathway oga04071   Sphingolipid signaling pathway oga04270   Vascular smooth muscle contraction oga04350   TGF-beta signaling pathway oga04360   Axon guidance oga04510   Focal adhesion oga04520   Adherens junction oga04530   Tight junction oga04611   Platelet activation oga04670   Leukocyte transendothelial migration oga04810   Regulation of actin cytoskeleton oga04921   Oxytocin signaling pathway oga05135   Yersinia infection oga05163   Human cytomegalovirus infection oga05200   Pathways in cancer oga05205   Proteoglycans in cancer oga05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:oga00001]  09130 Environmental Information Processing   09132 Signal transduction    04350 TGF-beta signaling pathway     100964845 (ROCK1)    04071 Sphingolipid signaling pathway     100964845 (ROCK1)    04024 cAMP signaling pathway     100964845 (ROCK1)    04022 cGMP-PKG signaling pathway     100964845 (ROCK1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100964845 (ROCK1)    04520 Adherens junction     100964845 (ROCK1)    04530 Tight junction     100964845 (ROCK1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100964845 (ROCK1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100964845 (ROCK1)    04670 Leukocyte transendothelial migration     100964845 (ROCK1)    04062 Chemokine signaling pathway     100964845 (ROCK1)   09152 Endocrine system    04921 Oxytocin signaling pathway     100964845 (ROCK1)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100964845 (ROCK1)   09158 Development and regeneration    04360 Axon guidance     100964845 (ROCK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100964845 (ROCK1)    05206 MicroRNAs in cancer     100964845 (ROCK1)    05205 Proteoglycans in cancer     100964845 (ROCK1)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     100964845 (ROCK1)   09171 Infectious disease: bacterial    05135 Yersinia infection     100964845 (ROCK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oga01001]     100964845 (ROCK1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oga03036]     100964845 (ROCK1) Enzymes [BR:oga01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100964845 (ROCK1) Protein kinases [BR:oga01001]  Serine/threonine kinases: AGC group   DMPK family [OT]    100964845 (ROCK1) Chromosome and associated proteins [BR:oga03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     100964845 (ROCK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Cortex-I_coil Pkinase_C APH Motif Other DBs NCBI-GeneID:  100964845 NCBI-ProteinID:  XP_012657473 Ensembl:  ENSOGAG00000012135 LinkDB All DBs Position Unknown AA seq 1290 aa AA seqDB search MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNV DKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDTIMKELDEEGSQRRNLEST VSQIEKEKMVLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILETSKSQTD KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLTLISQEKNNLEIDLN YKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEERETREKAENRV VQIEKQCSMLDVDLKQSQQKLEHLAENKERMEDEVKNLTLQLEQESNKRLLLQNELKTQA FEADNLKVLQKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFST LYKTQVKELKEEIEEKNRENLKKIQELQNEKWFVQLEETNSMLTKDIELLRKENEELTEK MKRAEEDYKLKKEEEIGNLKAAYEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQ DLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNEMQAQLVEECTHRNELQMQLASKES DIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVV SSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGE CRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCH VKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFV RASPRTLSTRSTANQSFRKVVKNTSGKTSS NT seq 3873 nt NT seq  +upstreamnt  +downstreamnt atgtcgactggggacagttttgagactcgatttgaaaaaatcgacaacctgctgcgggat cccaagtcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat ttggattttcctgccttaagaaaaaacaaaaacattgacaactttttaagcagatataaa gatacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtcaag gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatctaccaggaag gtatatgctatgaagcttcttagcaaatttgaaatgattaagagatctgattctgctttt ttctgggaagaaagagacatcatggcttttgctaacagtccctgggttgttcagcttttc tatgcattccaagatgatcgttatctctacatggtgatggaatacatgcctggtggagat cttgtaaacttaatgagcaactatgatgtacctgaaaaatgggcacgtttctatactgca gaagtagttcttgcattggatgcaattcattccatgggttttatccatagagatgtgaag cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattat atttccccagaggtattaaaatcccaaggtggtgatggttattatggaagagaatgtgac tggtggtctgttggggtatttttatatgagatgcttgtaggtgatacacctttttatgca gattctctggttgggacttatagtaagattatgaaccataaaaattcacttaccttccct gatgacaatgacatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga gaagtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat gatcagtgggcttgggaaacccttcgagacactgtagcaccagtcgtacctgatttaagt agtgacattgatactagtaattttgatgacctggaagaagataaaggagatgaagaaaca ttccctattcctaaagcttttgttggcaatcagctaccttttgtaggatttacatattat agcaatcgtagatatttatcttcagcaaatcctaatgataacagaactagctccaatgtg gataaaagcttgcaggaaagtttgcaaaaaacaatctataagctggaagaacagctacat aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaatataaaacta gacacaataatgaaagaattggatgaagagggaagtcaaagaagaaatctagaatctaca gtgtcccaaatagagaaagaaaaaatggtgctacagcatagaattaatgaataccaaaga aaagctgagcaggaaaatgaaaagaggagaaatgtagaaaatgaagtttctacattaaag gatcaattggaagacttaaagaaagtaagtcagaattcacagcttgctaatgagaagctg gcacaattacaaaaacagctagaagaagccaatgacttacttaggacagaatcggacaca gcagtaagattaaggaagagtcacacagagatgagcaagtcaattagtcagctagagtcc ctgaacagagaattgcaagagagaaatagaattttagagacttcaaaatcacaaacggac aaggattattaccagctacaggctgtattggaagctgaacgaagagacaggggtcatgat tctgagatgattggagacctgcaagctcgaattacatctttgcaagaggaggtgaagcat ctcaaacataatcttactctcatttcacaggaaaagaataatttagagatagatttaaac tataaacttaaatcattacaacagcggttagaacaagaggtaaatgaacacaaggtaacc aaagctcgtttaactgacaaacatcagtctattgaagaggcaaagtctgttgcaatgtgt gagatggaaaaaaagctgaaagaagagagagaaactcgagagaaggctgaaaatagggtt gttcagattgagaaacaatgttccatgttagatgttgatctgaaacaatctcagcagaag ctagagcatttggctgaaaataaagaaaggatggaggatgaagttaagaatctaaccctg caactggagcaggaatcaaataagcgactgttgttacaaaatgaattgaagactcaagca tttgaggcggacaatttaaaggttttacaaaagcagatgaaacaggaaataaatacttta ttggaagcaaagaggttgttagaatttgagttagctcagcttacaaaacaatatagagga aatgaaggacaaatgcgggaactacaagatcagcttgaagccgagcagtatttctcgaca ctttataaaacccaggtaaaagaacttaaagaagaaattgaagaaaaaaacagagaaaat ttaaagaaaatacaggaactgcaaaatgaaaagtggtttgttcagcttgaagaaacgaac agcatgctaaccaaagacattgaattattaagaaaagaaaatgaagagctaactgagaaa atgaagagggcagaggaagactataagttgaagaaggaggaggagatcggtaatcttaaa gctgcctatgaaaagaatatcaatactgaacgaactcttaaaacccaggctgttaacaag ctggcagaaataatgaaccgaaaagattttaaaattgatagaaagaaagctaatacacaa gatttgagaaagaaagaaaaggaaaatcgaaagctacaactggaactcaaccaagaaaga gaaaaattcaaccagatggtagtgaaacatcagaaggaactgaatgagatgcaagcgcaa ttggtagaagaatgtacgcataggaatgagcttcagatgcagttggctagcaaagagagt gatatcgagcaattgcgtgctaaacttttggacctttcggattctacaagtgttgctagt tttcctagtgctgatgaaactgatggaaaccttccagaatcaagaattgaaggttggctt tctgtaccaaatagaggaaatatcaaacgatatggctggaaaaaacagtatgttgtagtt agcagcaaaaaaattttgttctacaatgatgaacaagacaaggaacaatccaatccatct atggtattggacatagataaattgtttcatgttcgacctgtaacccaaggagatgtgtat agagctgaaactgaagaaattcctaaaatattccagatactatatgcaaatgaaggtgaa tgtagaaaagatgtagagatggaaccagtacaacaagcagagaaaaccaatttccaaaat cacaaaggccatgagttcattcctaccctctaccactttcctgccaattgtgaggcctgt gccaaacctctctggcatgtttttaagccacccccagccctagagtgtcgaagatgccat gttaagtgccacagagatcacttagataaaaaagaagatttaatttctccatgtaaagta agttatgatgtaacatcagcaagagatatgctgctgttagcatgttctcaggatgaacaa aaaaaatgggtaacacatttagtaaagaaaatccctaagaatccaccatctggttttgtt cgtgcctcccctcgaactctttctacaagatccacagcaaatcagtctttccgaaaagtg gtcaaaaatacatctggaaaaactagcagttaa

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