Orcinus orca (killer whale): 101278097
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Entry
101278097 CDS
T05247
Symbol
NOTCH3
Name
(RefSeq) neurogenic locus notch homolog protein 3 isoform X2
KO
K20995
Notch 3
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01522
Endocrine resistance
oor04330
Notch signaling pathway
oor04371
Apelin signaling pathway
oor04658
Th1 and Th2 cell differentiation
oor04919
Thyroid hormone signaling pathway
oor05165
Human papillomavirus infection
oor05200
Pathways in cancer
oor05206
MicroRNAs in cancer
oor05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101278097 (NOTCH3)
04371 Apelin signaling pathway
101278097 (NOTCH3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
101278097 (NOTCH3)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101278097 (NOTCH3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101278097 (NOTCH3)
05206 MicroRNAs in cancer
101278097 (NOTCH3)
09162 Cancer: specific types
05224 Breast cancer
101278097 (NOTCH3)
09172 Infectious disease: viral
05165 Human papillomavirus infection
101278097 (NOTCH3)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
101278097 (NOTCH3)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
Ank_2
Ank
Notch
EGF_2
NODP
Ank_4
NOD
Ank_3
Ank_5
EGF_3
cEGF
JAG1-like_EGF2
DL-JAG_EGF-like
Motif
Other DBs
NCBI-GeneID:
101278097
NCBI-ProteinID:
XP_004277676
LinkDB
All DBs
Position
3:13730449..13764590
Genome browser
AA seq
2320 aa
AA seq
DB search
MGPGPRGRRRRRLMSPPPPLPSVRTLPLLLLLAGPGAAAPSCLDGSPCANGGRCTQLPSR
EAACLCPPGWVGERCQLEDPCHSGPCAGHGVCQSSVVAGTARFSCRCPRGFRGPDCSLPD
PCLSSPCAHGARCSVGSDGRYVCSCPPGYQGRSCRSDVDECRMGGPCRHGGTCLNTPGSF
RCQCPAGYTGPLCESPLVACAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP
GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV
CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCH
EDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR
GYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDMDECQSSPCVNG
GVCKDRVNGFSCTCPSGFSGAMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTV
CEHNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLV
DKYLCRCPPGTTGVNCEVNIDDCASNPCTFGICRDSINRYDCVCQPGFTGPLCNVEINEC
ASSPCGEGGSCVDGENGFQCLCPPGSLPPLCLPPSHPCAQEPCSHGVCHDAPGGFRCVCE
LGWSGPQCSQSLARDACESHPCWAGGTCTSDGTGFRCTCPPGVQGRQCELLSPCTPNPCE
HGGYCESAPGQPAVCSCPPGWQGSRCQQDVDECAGPSPCGPHGTCANLAGSFSCTCHEGY
SGSSCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSSPCGPGTC
TDHVASFTCTCPPGYGGFLCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRLGYTGTHCQH
EADPCLSRPCLHGGVCTAAHPGLRCACPEGFTGTQCQTLVDWCSRTPCQNGGHCARTGAS
FYCLCPSGWSGRLCDIQSLPCREAAAQIGVPLEQLCQAGGQCVDKDSSHYCVCPEGHTGS
HCEQEVDPCLAQPCQHGGTCRGYMGGYVCECPAGYTSDNCEDDMDECASQPCQHGGVCID
LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDPGPRCLHNGTCVDLVGGFRCTCPPGYTG
LRCEADINECRPGACHAAHTRDCLQDPGGGFHCLCHAGFTGPHCQTVLSPCESQPCQHGG
QCHPNPGAGGALTFSCHCVPPFSGPRCERVARSCWELQCPVGVPCQQTVRGPRCACPPGL
SGPACRGSRGSTLGAANASCVTSPCLHGGSCRPETLAPFFRCACASGWAGPRCEIPAAVP
EAPEEPSCPRAACEAKSGDKRCDRECNSPGCGWDGGDCSLSVSDPWRQCAALQCWLLFNN
SRCDPACSSPACLYDNFDCRAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLD
CAGEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSGILRTSLRFRLDENGQAMVFPYH
RPGPGSESRNRRELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVER
LDFPYPLRAARGEPLELPEPSVPLLPLLAASAVFLLVILVLGVMVARRKREHSTLWFPEG
FALHKDAAAGHKGRREPVGQDALGMKNMAKGESLMGEVATDWMDTECPEAKRLKVEEPGV
GAEDAVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFC
GGALEAIPADEDEAEDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLL
DAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVE
GMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLA
AREGSFEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPGPHGL
GPLLCPPGAFLPGLKVAQSGGKKSRRPPGKAGLGPQGTRGRGKKLTLACPGPLAESSVTL
SPVDSLDSPRPFGGPPASPGGFPLEGPYAAAAATAVSLAQLGGAGRAGLGRQPPGGCVLS
LGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGNPVSPQERPPPYLAAPGHGD
EFPAAGAHSSPPKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSDSTPSPATATGA
TAAGTLSAQPLPLSVPGPLAQSQTQLGSQPEVTPKRQVLA
NT seq
6963 nt
NT seq
+upstream
nt +downstream
nt
atggggccggggccccggggccgccgccgccgtcgcctgatgtcgccgccgccacccctg
ccgtccgtgcggacgctgcccttattgctactgctagcggggccgggggctgcagcgccc
tcttgcctggatggaagcccgtgtgcgaatggaggtcgctgcacccagctgccctcccgg
gaggctgcctgcctgtgcccaccaggctgggtgggtgaacggtgtcagctggaagacccc
tgccattccggcccctgtgctggccatggtgtctgccagagctcggtggtggcaggcacc
gcccggttctcctgccgctgcccccgtggcttccgaggcccagactgctccctgccagac
ccctgcctcagcagcccctgtgcccatggtgcccgctgctcggtggggtccgatggccgc
tacgtctgctcctgcccacctggctaccagggccgcagctgccgaagcgacgtggatgag
tgccggatgggcggaccctgccgccatggtggcacctgtctcaacacacctggctccttc
cgctgccagtgcccagctggctacacagggccactgtgtgagagccccttggtggcctgt
gccccctcgccgtgccgtaacgggggcacctgtagacagagtggcgacctcacctacgac
tgtgcctgccttcctgggttcgagggccagaactgtgaagtgaatgtggacgactgtcca
gggcaccgatgtctaaatggggggacgtgtgtggacggtgtcaacacctacaactgccag
tgccctcctgagtggacaggccaattctgtacggaggacgtggacgagtgtcagctccag
cccaacgcttgccacaatgggggtacttgcttcaacacgctgggtggccacagctgtgtg
tgtgtcaatggctggacaggcgagagctgcagtcagaatattgatgactgtgccacggcc
gtgtgcttccatggggccacctgccatgaccgtgtggcctccttctactgtgcctgcccc
atgggcaaaactggacttctgtgtcatctggatgacgcctgcgtcagcaacccctgtcac
gaggatgctatctgcgacacgaacccggtgaacggcagggccatctgcacctgtccacct
ggcttcacaggcggggcgtgtgaccaggatgtggatgagtgttccatcggtgccaaccct
tgtgagcacctgggccggtgcgtgaacacacagggctcattcctgtgccagtgcggccgt
ggctacactggtccgcgttgcgagaccgatgtcaacgagtgcctctccggcccctgccgc
aaccaggccacgtgcctcgaccgtataggccagtttacctgcatctgcatggcaggcttc
acaggcacttattgtgaggtggacatggacgagtgtcagagcagcccgtgtgtcaacggc
ggagtctgcaaggacagagtcaatggcttcagctgcacctgcccctcgggcttcagcggg
gctatgtgtcagctggacgtggatgaatgcgccagcacaccctgccggaatggagccaag
tgcgtggaccagccggatggctatgagtgccgctgcgcagagggcttcgagggcacggtg
tgtgagcacaacgtggatgactgctcgccagacccttgccaccatgggcgctgtgtggat
ggcatcgccagtttctcgtgcgcctgtgccccgggctacaccggcacgcgctgtgaaagc
caggtggacgagtgccgaagccaaccctgccgccatggtggcaaatgcctagacctggtg
gacaaatacctctgccgctgccctcccggcaccacaggtgtgaactgcgaggtgaacatt
gatgattgtgctagcaacccctgcacctttggaatctgccgggacagcatcaaccgctat
gactgtgtctgccagcctggcttcacagggcctctctgcaacgtggagatcaacgagtgt
gcgtccagcccatgcggtgaggggggctcctgcgtggatggtgaaaatggcttccaatgc
ctctgcccacctggctccctgcccccgctctgtcttcccccaagccatccctgcgcccaa
gaaccctgcagtcatggcgtctgccacgacgcgcctggagggttccgctgcgtgtgtgag
cttggctggagtggccctcagtgcagtcagagcctcgctcgagatgcctgtgaatcccat
ccgtgctgggcaggcggcacctgcaccagtgatggaacgggcttccgctgtacctgtccc
cctggtgtccagggccgtcagtgtgagctgctgtccccctgcaccccaaatccctgtgaa
catgggggctactgtgagtctgcccctggccagccggctgtctgctcctgcccccctggt
tggcaaggctcacgatgtcagcaggacgtggatgaatgtgctggcccctcaccctgtggt
ccccatggtacctgcgccaacctggcagggagtttcagctgtacctgccacgagggctat
agtggctcttcctgtgatcaggacatcgatgactgtgaccccaacccctgcctgaatggt
ggctcatgtcaggatggagtgggctccttttcctgctcctgcctacctggctttgctggc
ccccgctgcgcccgagatgtggatgagtgtctgagcagcccctgcggcccaggcacctgc
acagaccacgtggcctccttcacctgcacctgcccgccgggttatggaggcttcctctgc
gagcaggacctacctgactgcagccccagctcctgcttcaatggtgggacctgcgtggat
ggtgtgaactcgttcagctgcctgtgccgcctgggctacactggcacacactgccaacac
gaggccgacccttgcctctcgcgaccctgcttgcacgggggcgtctgcactgccgctcac
cccggcttgcgctgtgcctgccctgaaggcttcaccggcacgcagtgccagacgctggta
gactggtgcagccgcacaccttgtcagaatgggggccactgtgcccggaccggggcctct
ttctactgcctttgcccctcgggatggagcggccgcctctgcgacatccagagtctaccc
tgcagagaggctgcagcccaaatcggggtgcctctggagcagctgtgtcaggctggtggg
cagtgcgtggacaaggacagctcccactactgcgtgtgcccagagggccacacaggcagt
cactgtgagcaggaggtggacccctgcttggctcagccctgccagcatgggggcacctgc
cgaggctacatgggaggttatgtgtgcgagtgtccagctggctacactagtgacaactgt
gaggatgacatggacgagtgtgcctcccagccctgccagcatgggggcgtctgcattgac
cttgtggcccgctatctctgctcgtgtcctccaggaacgctgggcgtgctctgcgagatt
aatgaggatgactgtggcccaggcccacccctggacccgggcccccggtgcctgcacaat
ggtacctgtgtggacctggtgggtggcttccgctgcacctgccccccgggatacactggc
ctgcgctgtgaggcggacatcaatgagtgtcgtccaggtgcctgccatgcggcacatacc
cgggactgcttgcaggacccaggtgggggcttccactgcctttgtcatgccggcttcaca
ggtccccactgtcagaccgtcttgtctccctgtgagtcgcagccatgccagcatggaggc
cagtgccaccccaaccccggcgctgggggagctctgactttctcttgccactgtgtcccg
ccgttctccggcccgcgctgcgagcgggtggcacgttcctgctgggagttgcagtgcccc
gtgggcgtcccgtgccagcagacggtccgtggaccgcgctgcgcctgtcccccggggctg
tcgggtcccgcctgccggggttcccgggggtcgacactgggagccgccaatgccagctgc
gtgacctccccctgcctccacgggggctcctgccgcccggagacgctggcgcccttcttc
cgctgcgcgtgcgcgtcaggctgggctgggccgcgctgtgagatacctgcagcggtgccc
gaggcccccgaggagccgtcttgcccgagagccgcctgcgaggccaaaagcggcgacaag
cgctgtgaccgggagtgcaacagcccaggctgcggctgggatggcggcgactgctcgctg
agcgtgagcgatccctggcggcagtgtgcggcgttgcagtgctggctcctcttcaacaac
agccgctgcgaccccgcctgcagctcgcccgcctgcctctatgacaacttcgactgccgc
gcaggcggccgggagcgcacctgcaacccggtgtatgagaagtactgcgcggaccacttt
gccgacggccgctgcgaccagggctgcaacacagaggagtgcggttgggatggactggac
tgtgcgggtgaggtgccagctctgctggcccgaggtgtcctggtgctcactgtgctgctg
ccgccggaggagctgctgcgctccagtgccgacttcctgcagcggctcagtggcatcctg
cgcacctctctgcgcttccgtctggatgagaacggccaggctatggtcttcccttaccac
cggcctggccctggctccgaatcccggaatcggcgggagctggcccctgaggtgatcggc
tctgtggtgatgctggagattgacaaccgtctgtgcctacagtcgcctgagaatgaccac
tgttttcccgacgcccagagtgcggcagactatctgggagccttgtcagcggtggagcgc
cttgacttcccgtacccactgcgggcggcacggggggaaccgctggagctgccggaaccg
agcgtgccgctactgcccctgctggctgcgagcgccgtcttcctgctggtcattctcgtc
ctgggcgtcatggtggcccgccgcaagcgtgagcacagcaccctctggttccccgagggc
ttcgcgctgcacaaggatgctgcagctggccacaagggccggcgggaacccgtgggccaa
gacgctctgggcatgaagaacatggccaagggtgagagtctgatgggggaggtggccaca
gactggatggacacagagtgcccggaggccaagcgactgaaggtagaggagcctggtgtg
ggagctgaggatgccgtggattgccgccagtggactcaacaccacctggttgccgccgac
atccgcgtggcaccagccatggcattgacgccaccacagggcgatgcagatgctgatggc
atggatgtcaacgtgcgtggtccagatggcttcaccccgctaatgctggcctccttctgc
gggggggccctggaagcaatcccagctgatgaggacgaggcagaagacacatcagccagc
atcatctcagaccttatctgccagggggcacagcttggggctcggaccgaccgcacgggt
gagacggccctgcacctggctgcccgctatgcccgggctgatgcggccaagcggctgctg
gatgcgggggcagacaccaatgcccaggaccactcaggccgcacccccctgcacacagcc
gtcactgctgatgcccagggcgttttccagattctcatccggaaccgctccacagacctg
gatgcccgcatggcagacggctccacagcgctgatcctggcggcccgcctggcagtggag
ggcatggtggaagagctcatcgccagccatgctgatgtcaatgctgtggatgaactcgga
aaatcagccttacactgggctgcagctgtcaacaacgtcgaggccaccttggccctgctc
aaaaatggagctaacaaagacatgcaagatagcaaggaggagactccgctgttcctggcc
gccagggagggcagctttgaggctgccaagctgctgctggaccactttgccaaccgtgag
atcacagaccacctggacaggctgccccgggatgtggcccaggagcggctgcaccaggac
atcgtgcgcttgctagaccagcccagtgggccccgtagcccccctggcccccacggcctg
gggcccttgctctgtccgcccggggccttcctcccaggcctcaaggtggcacagtccggg
ggcaagaagagccggaggcctcctgggaaggcggggctggggcctcagggcacccggggg
cggggcaagaagctgaccctggcctgcccggggcccttggccgagagctctgtcacgctc
tcgccggtggactcgctggactccccacggccctttggtggcccccccgcgtcccctggc
ggcttccccctcgaggggccctacgcggctgccgcggccacagccgtgtctctggcacag
ctcggtggcgcaggccgggcaggtctcgggcgccagccccccgggggctgtgtgctcagc
ctgggcctgctgaaccccgtggccgtccccctcgactgggcccggctgcccccacctgcc
cccccaggtccctctttcctgctgccgctggccccgggaccccagctgctgaaccccggg
aaccccgtgtccccccaggagcggcccccaccgtacctggcagccccaggacatggcgat
gagttccccgcggccggggcccacagcagccccccaaaggcccgcttcctgcgggtcccc
agcgagcacccttacctgaccccatccccagagtcccccgagcactgggccagcccctca
cctccctcactctcggactggtccgactccacgcccagcccggccactgccaccggggcc
acggccgctgggacactgtctgcccagccgctccccctgtcggtccctggccctcttgct
cagtcccagacccagctagggtcccagcctgaagtcacccccaagaggcaagtgttggcc
tga
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