Orcinus orca (killer whale): 101278812
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Entry
101278812 CDS
T05247
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04012
ErbB signaling pathway
oor04014
Ras signaling pathway
oor04360
Axon guidance
oor04510
Focal adhesion
oor04660
T cell receptor signaling pathway
oor04810
Regulation of actin cytoskeleton
oor05170
Human immunodeficiency virus 1 infection
oor05206
MicroRNAs in cancer
oor05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101278812 (PAK4)
04014 Ras signaling pathway
101278812 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101278812 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101278812 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
101278812 (PAK4)
09158 Development and regeneration
04360 Axon guidance
101278812 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101278812 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
101278812 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101278812 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101278812 (PAK4)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101278812 (PAK4)
Protein kinases [BR:
oor01001
]
Serine/threonine kinases: STE group
STE20 family
101278812 (PAK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
hnRNP_Q_AcD
RIO1
KIND
Kdo
Motif
Other DBs
NCBI-GeneID:
101278812
NCBI-ProteinID:
XP_004271359
LinkDB
All DBs
Position
20:46150000..46196453
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AA seq
594 aa
AA seq
DB search
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPVE
QATTARGGPEKAGGQGRVAGRSEAGGSSGDRRRVGPDKRPKSSREGSGGPQESSRDKRPL
SGPDVGTPHQPAGLASGAKVAAGRPFNTYPRADTDHPSRGAQGEPHNVAPNGPSVGGLAV
PQSSSASRPPARAHGPPSPGVLGPHASEPQLAPPARTLAAPAAPPAPGPPGPRSPQREPQ
RVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGRLVAVKKMDLRKQ
QRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQI
AAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVG
TPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKN
LHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atgtttgggaagaagaagaagcgggttgagatctcggcaccgtctaacttcgagcaccgc
gtgcacacgggcttcgaccagcacgagcagaagttcacggggctgccccgccagtggcag
agcctgatcgaggagtcagctcgccggcccaagcccctcatcgaccccgcctgcatcacc
tccatccagcctggggcccccaagaccatcgtgcggggcagcaaaggcgccaaggatggg
gccctcacgctgctgctcgacgagtttgagaacatgtcggtgacgcgctccaactccctg
cggagagacagcccgccgccacccgcccgtgcccgccaggaaaacgggatgcccgtggag
caggccaccacggccagagggggcccagagaaggcgggcggtcaaggccgggttgccggt
cgcagcgaggcgggtggcagcagtggagacaggcggcgggtggggccggacaagaggccc
aagtcttccagggagggctcaggggggccccaggagtcctcccgggacaagcggcccctc
tctgggcctgacgtcggcaccccccaccagcctgccggtctggccagcggggcgaaagtg
gcagctggccggccctttaacacgtacccgcgggccgacacggaccacccatcccggggc
gcccagggggagcctcacaacgtggcccccaatgggccatcggtggggggcctggccgtc
ccccagtcctcctctgcctcccggccccccgctcgagcccacggcccccccagccctgga
gtgctgggcccccacgcctccgagccccagctggcccctccagcccgcaccctcgccgcc
cccgctgcgccccccgcccccggaccccccggaccccgctcgccacagcgggaaccccag
cgagtgtcccacgagcagttccgggctgccctgcaactggtggtggaccccggcgaccct
cgctcctacctggacaacttcatcaagatcggcgagggctccacgggcatcgtgtgcatc
gccaccgtgcgcagctcgggccggctggtggccgtcaagaagatggacctgcgcaagcag
cagaggcgcgagctgctcttcaatgaggtggtgatcatgagggactaccagcatgagaac
gtggtggagatgtacaacagctacctggtcggggacgagctctgggtggtgatggagttc
ctggagggaggcgccctcaccgacatcgtcacccacaccaggatgaacgaggagcagatc
gccgccgtgtgcctggccgtgctgcaggccttgtccgtgctccacgcccagggggtcatc
caccgggacatcaagagcgactccatcttgctgacccacgatggcagggtgaagctgtcg
gactttgggttctgtgcccaggtgagcaaggaggtgccccggaggaagtccctggtcggc
acgccctactggatggccccggagctcatctcccgcctcccctacgggccagaggtggac
atctggtctctgggggtgatggtgatcgagatggtggatggggagcccccctacttcaat
gagccacccctcaaagccatgaagatgattcgggacaacctgccaccccgactgaagaac
ctgcacaaggtgtcgccatccctgaagggcttcctggaccgcctgctggtgcgtgacccg
gcacagcgggccacggcggctgagctgctcaagcacccattcctggccaaagcgggcccg
cccgccagcatcgtgcccctcatgcgccagaaccgcaccagatga
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