Orcinus orca (killer whale): 101280974
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Entry
101280974 CDS
T05247
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor03440
Homologous recombination
oor03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
101280974 (TOP3A)
03460 Fanconi anemia pathway
101280974 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
oor03032
]
101280974 (TOP3A)
03400 DNA repair and recombination proteins [BR:
oor03400
]
101280974 (TOP3A)
Enzymes [BR:
oor01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
101280974 (TOP3A)
DNA replication proteins [BR:
oor03032
]
Eukaryotic type
DNA Topoisomerases
101280974 (TOP3A)
DNA repair and recombination proteins [BR:
oor03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
101280974 (TOP3A)
FA (Fanconi anemia) pathway
101280974 (TOP3A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
zf-GRF
Toprim
zf-C4_Topoisom
zf-C2H2_10
Zn_ribbon_recom
Motif
Other DBs
NCBI-GeneID:
101280974
NCBI-ProteinID:
XP_004266833
LinkDB
All DBs
Position
19:19552025..19577496
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AA seq
1003 aa
AA seq
DB search
MIFPVVRRALTWLPRPGSRALTLADMEVALRGVRKILCVAEKNDAAKGIADLLSGGRMRR
REGLSRFNKIYEFDYRLRGQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
YCPENFLDIKKTLEREAQQCQVLVIWTDCDREGENIGFEIIHVCKAVKPSLQVLRARFSE
ITARAVQAACENLMEPDRRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPETFHRIRVTHDHRDGAVEFSWKRHRLFNHTACLVLY
QLCMEDPRATVVEVRSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLDLTALVEEQTHDPRWGPFAQSILERGGPTPRNGNKSDQAHPPIHPT
KYTDSLQGDEQRLYELIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLVILARNYLDV
YPYDRWSEKTLPVYSRGSCFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKLVVLQQQVQKYKQVFIEAMAKAQRLDEALSQYFGAGVELAQQEAIFPAVPEPVRKCPQ
CGKDMVLKTRKSGGFYLSCTGFPECRSAVWFPDSVLEASRDGSVCPVCQPHPVYRLKFKF
KRGSLPPTMPLEFVGCVGGCDETLREILDLRFSRGPARAGQPVSQPSGHLQASQPLDRMG
SSQHGHPQPPAITPSNALARTAPLPAAEGEGNSVTCNCGREALLLTVRKEGPNQGRQFYK
CSGGGCSFFLWADSGHPEAGGPPSEVPRPPGGSLGRPPGSGKPLGGPGSPGDGGGGARCL
CSQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGTFGGPPWAGARGGSR
EPEARSKRARAGSSDAGSAAKKPRKCSLCHQPGHTRPFCPQNR
NT seq
3012 nt
NT seq
+upstream
nt +downstream
nt
atgatcttccctgtcgtccgccgcgcgctcacctggctgccgcggcctgggagccgggcg
ctgaccctcgccgacatggaggtggccctgcgaggcgtgcggaagatcctctgcgtggcc
gagaagaacgacgcggccaagggcatcgcggacctgttgtccggcggccgcatgcggcgg
agagaaggactttccagattcaacaagatctatgaatttgattatcgtctgcgtggccag
aacgtcaccatgataatgacttcagtctcgggacacttgctggctcatgatttccagatg
cagtttcgcaagtggcagagctgcaatcctcttgtcctctttgaagcagaaattgaaaag
tactgcccagagaattttttagacatcaagaaaactctggagcgagaggctcagcagtgc
caggtgctggtgatctggaccgactgcgacagagaaggtgaaaacatcgggtttgagatc
atccacgtgtgcaaggctgtgaagcccagcctgcaggtgctgcgagcccgtttctccgag
atcaccgcccgcgctgtccaggcggcctgtgaaaacctgatggagcccgaccgcagagtg
agcgacgccgtggacgtgagacaggagctggacctgcggatcggggctgccttcaccagg
ttccagaccctgcggctgcagaagatcttccctgaggtgttggcggagcagctgatcagt
tatggcagctgccagttccccaccctggggttcgtggtggagaggttcaaagccattcag
gcatttgtgccagaaaccttccacagaatcagagtgactcacgaccacagggatggcgca
gtggagttcagctggaaaaggcatcggcttttcaaccacacggcttgtctcgtcctctat
cagctgtgcatggaggatcccagggcgaccgtggtggaggtcaggtccaaggcaaaaagc
aagtggaggcctcaagctttggacactgtggagcttgagaagctggcttctcgaaagttg
aggataaatgctaaagaaaccatgaggattgctgaaaagctctacactcaagggtacatc
agctatccccgaactgaaacaaacattttccccaaagacttagacctgaccgcgctggtg
gaggagcagacccacgatccacgctgggggcccttcgcccagagcattctagagcggggc
ggccccactccacgcaacgggaacaagtctgaccaagctcaccctccgatccaccccacc
aagtacacggacagcctgcagggggacgagcagcgactgtacgagctcatcgtccgccac
ttcctggcctgctgctcccaggatgcccagggccaggagaccaccgtggagattgacatc
gcacaggagcgcttcgtggcccacggcctcgtaatcctggcccgaaactatctggacgtg
tacccctacgatcgctggagtgaaaagaccctccctgtctacagtcgaggctcctgcttt
cagcccagcaccgtggagatggtggacggggagaccagtccaccccagctgctcactgag
gccgaccttattgccctcatggagaagcacggcatcggtaccgacgcgacgcacgcggag
cacatcgagaccatcaaggcccgaatgtacgtcgggctcacgccagacaagcgctttctc
cccgggcacctgggcatggggcttgtggaaggctatgactccatgggctacgagatgtcc
aagcctgacctgcgggccgagctggaggctgacctgaagctcatctgcgaggggaagaag
gacaagctcgtggtcctgcagcagcaggtgcagaagtacaagcaggtcttcatcgaagcc
atggccaaagcccagaggttggacgaggccttgtcgcagtactttggggcaggggtggag
ctagcccagcaagaagccatcttcccagctgtgccagagcccgtcaggaagtgcccacag
tgcggcaaggacatggtcctcaagaccaggaaaagcggcgggttctacctcagctgcacg
gggttcccggaatgtcgctcggccgtgtggttcccggacagtgtgctggaggccagcagg
gacgggagcgtgtgtccagtgtgtcagccacaccccgtttacaggttgaagttcaagttt
aagcgaggcagccttcccccaaccatgccactggaatttgtcggctgcgttggtggctgt
gacgagaccctgagggagatcttggacctcaggttttcacgggggcccgcccgagctggc
cagccggtcagccagccctccggccacctgcaggccagccagcccctggacagaatgggc
agcagccagcacggccacccccagcctcctgccatcacgccctcgaatgctctggccagg
actgcgcccctgcccgccgccgagggcgaaggcaattcggtgacctgcaactgtggccgg
gaggccctgctgctcaccgtccggaaggaggggcccaaccagggccgccagttctacaag
tgcagcggcggcggctgtagcttcttcctctgggccgacagcggccacccagaagcaggg
gggcctccctccgaggtgcccagacccccgggcggctcactgggacgcccgccgggctca
gggaagcccctgggcgggcccggaagccccggcgatggtggcggcggcgcacgctgcctg
tgcagccagcccgctgtcacgcgcactgtgcagaaggacgggcccaacaaggggcgccag
ttccacacgtgcgccaagccccgggagcagcagtgcggcttcttccagtgggtggacgag
aacgtggccccagggacctttggaggccccccctgggcaggagccagaggaggaagccgg
gagccggaggccagaagcaaaagggcccgggctggttcctcggacgccgggtccgcggcc
aagaaaccccggaagtgcagcctttgccaccagcctggacacacccgtcccttctgtcct
cagaacagatga
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