KEGG   Cutibacterium acnes subsp. defendens ATCC 11828: TIIST44_07740
Entry
TIIST44_07740     CDS       T01972                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
pad  Cutibacterium acnes subsp. defendens ATCC 11828
Pathway
pad00470  D-Amino acid metabolism
pad00550  Peptidoglycan biosynthesis
pad01100  Metabolic pathways
pad01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:pad00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    TIIST44_07740
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    TIIST44_07740
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    TIIST44_07740
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:pad01011]
    TIIST44_07740
Enzymes [BR:pad01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     TIIST44_07740
Peptidoglycan biosynthesis and degradation proteins [BR:pad01011]
 Precursor biosynthesis
  Amino acid ligase
   TIIST44_07740
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4 ATP-grasp_3
Other DBs
NCBI-ProteinID: AER06014
LinkDB
Position
1640681..1641778
AA seq 365 aa
MNRIHVAVIFGGMSSEHSISCLSAANVVAAIDAERFDVSGVGISPQGIWVRYGADEILAL
PGTGQLPTVEMGDRPLVSVKQMPEGTCIVDTEGNVDAVQVVFPVLHGPFGEDGTIQGLLE
MAGVRYVGCGVAASANCMDKHLTKMILSEAGVLVGPYVVVRDHEWREDRNAVLKAASRLE
YPLFVKPARGGSSIGISRVTSPEHLETAIEMAREHDSKVLIEQGIRGREIECSVIDGRHG
AAPRASVPGEIVVHDPDGFYDFEAKYLSGEQKASVQAHANLDDVTRRRVQEVAIKAFQVL
GCEGLARIDTFVTPDGAVYVNEPNTMPGFTRSSGFPLMWQASGMTYAQIVSELIELALER
PLGLR
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgaatcgcatccacgtcgctgtcatcttcggggggatgagttcggagcattcgatctcc
tgcctttcggcggcgaacgtggtagctgcgattgacgccgaacgattcgatgtctccggt
gtcggtattagcccccaggggatctgggtgcgatatggggctgacgaaatcctcgctctt
cccggtaccggacaacttcctactgtcgaaatgggagatcgtcctctggtgtcggtcaaa
cagatgcccgagggcacctgcatcgtcgataccgagggtaatgtcgatgcagtccaggtg
gtatttccggtattgcacggaccattcggtgaagacggcaccattcagggcctgctggag
atggccggagtgcgatatgtcgggtgcggggtggcagccagcgctaactgcatggacaag
cacctcaccaagatgatcctctcggaagctggagtattggtcggaccctacgttgttgtg
cgtgatcatgagtggcgtgaggacagaaatgctgttctcaaagctgcatctcgcctggaa
tacccgctattcgtgaagccggcccgcggtggatcttcgatcggcatttctcgcgtgaca
agcccagaacacctggaaactgcgattgagatggcccgcgagcacgacagcaaagtcctc
attgagcaggggattcgtggtcgcgagatcgagtgctctgtcattgatggccgtcatggt
gctgcccctcgggcctccgtgcccggtgagattgtcgttcatgaccctgacggcttctat
gacttcgaagctaaatacctcagtggagagcagaaagcatccgttcaggctcatgcaaat
ctggacgatgtgacccgcagacgggtgcaagaagtcgcgatcaaagcgttccaggtgctt
ggctgtgaagggcttgcccgtatcgacacgttcgtcacccctgacggcgccgtttacgtg
aatgagcccaataccatgcccggatttacccgcagctcaggattcccactcatgtggcag
gccagtggcatgacgtacgcccagattgtcagtgagctcattgagttagctctggaaagg
cccctcggcctgcgctga

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