Cutibacterium acnes SK137: HMPREF0675_3960
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Entry
HMPREF0675_3960 CDS
T01215
Symbol
menD
Name
(GenBank) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
pak
Cutibacterium acnes SK137
Pathway
pak00130
Ubiquinone and other terpenoid-quinone biosynthesis
pak01100
Metabolic pathways
pak01110
Biosynthesis of secondary metabolites
pak01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
pak00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
HMPREF0675_3960 (menD)
Enzymes [BR:
pak01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
HMPREF0675_3960 (menD)
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Gene cluster
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Motif
Pfam:
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
ADD99456
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Position
985471..986997
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AA seq
508 aa
AA seq
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MNPSTAVARRLVNALVEAGVEHVVYCPGSRDAPIGYALADAETAGWLRVYVRLDERSAGF
VALGLGRAGCPAALVTTSGTAVANIHPAVLEADAAGVPLIVLSADRPAEMWHTGANQTTV
QTGIFGSAPRLSTDVPAGFPADERLDALVLRAVTAATGALSADPGPVHLNVSFRDSLVPD
GPWQPQALVPRRVSSFPTAPTPLVMPARTVVVAGDGAGSLARELAQQGGWPLLAEPTSGS
RVGDNALTDYQTVLGSELVDDVEAVLVLGHPTLSRPVSRLLARPDVTVVTDRSRWTDVAG
VARVVTGPVELAEIDTDPAWLGRWKDADRPVVPTAKQRLCRDIWWACTTPNAPVLVIGAS
EVIRCFDRFAVPGDIAPTALANRGLAGIDGTIATAIGVGLGTGRPVRVVVGDLTFAHDAM
SLLLGETEPEPDVQVVVLDDRGGAIFSGLEHAAAPAPVLRRMFLTPQRLDSAALAHALGA
SHRRVSPDDLQFLDEPVVGRQVVSVPLT
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccctctacagcagtcgcccgacgtctggtgaatgctctcgttgaggccggggtc
gaacacgtcgtgtattgccccggatcccgggatgcccctattgggtatgcgttggctgat
gctgaaactgctggatggctgcgggtttacgtgcgtctggacgagaggtcagctggtttc
gtcgccctagggctgggccgggctggctgcccggctgcgttagtcacgacctcgggcacc
gcggtggccaacattcacccggccgttctcgaggccgacgctgccggggtgccgcttatc
gtcctctcggccgaccgtcccgccgagatgtggcacacgggggctaaccagacgactgtc
caaaccgggatcttcgggtccgcgccacgtctcagcactgatgtgccggccggattcccc
gccgacgaacgcctcgacgctcttgttctacgggctgtgacagccgcgaccggggcgctg
agcgccgacccgggcccggtgcacctcaacgtgagctttcgtgactcgctcgtgcctgac
gggccgtggcagccgcaggcattggtgccccgtcgggtgagttccttcccgactgcaccg
acgccgctggtgatgcctgcccggacggtcgtcgtggccggggacggtgccggatcgctc
gcccgcgagttggcacagcagggcggatggcctctgctggccgaacccacctcgggctcc
cgggtcggggacaacgctctcaccgactaccagacggtcctgggtagcgagctggtcgac
gatgtcgaggctgtcctcgtcctgggccaccccactttgtcgcgcccggtgtcgcggctg
ttagcgcgtcccgacgttaccgtcgtaactgatcgcagtcggtggactgacgtcgccggg
gtagcccgggtcgtcacgggaccggtggaactggccgagatcgataccgacccggcgtgg
ctcggccgctggaaggacgcagaccggcccgtcgtaccgaccgccaagcagcgcctgtgc
cgcgacatctggtgggcctgtacgaccccgaacgcccccgtgcttgtcattggcgcctcc
gaagtcatccgctgtttcgatcgatttgctgtgcccggcgacatcgctccaacggcgctg
gccaaccgggggctggcaggcatcgacggcaccatcgctacggcgatcggtgtggggttg
ggcaccggtcggccggtgcgtgttgtcgtcggcgatctcaccttcgcccacgacgccatg
tccctgctgttgggagagaccgaacctgaacctgacgtgcaggttgtcgtcctggacgac
cgtggtggggcgatttttagcggccttgagcacgccgctgcccccgcgcctgtgctgcga
cggatgtttttgacccctcagcgtctcgattccgccgccctcgcgcacgccctcggagcg
agtcaccggagggtctctccagacgacctccagttcctcgacgaaccggttgtgggtcgt
caggtcgtttcggtaccactcacctga
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