Pteropus alecto (black flying fox): 102885749
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Entry
102885749 CDS
T02993
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale01521
EGFR tyrosine kinase inhibitor resistance
pale01522
Endocrine resistance
pale01524
Platinum drug resistance
pale04010
MAPK signaling pathway
pale04012
ErbB signaling pathway
pale04014
Ras signaling pathway
pale04015
Rap1 signaling pathway
pale04022
cGMP-PKG signaling pathway
pale04024
cAMP signaling pathway
pale04062
Chemokine signaling pathway
pale04066
HIF-1 signaling pathway
pale04068
FoxO signaling pathway
pale04071
Sphingolipid signaling pathway
pale04072
Phospholipase D signaling pathway
pale04114
Oocyte meiosis
pale04140
Autophagy - animal
pale04148
Efferocytosis
pale04150
mTOR signaling pathway
pale04151
PI3K-Akt signaling pathway
pale04210
Apoptosis
pale04218
Cellular senescence
pale04261
Adrenergic signaling in cardiomyocytes
pale04270
Vascular smooth muscle contraction
pale04350
TGF-beta signaling pathway
pale04360
Axon guidance
pale04370
VEGF signaling pathway
pale04371
Apelin signaling pathway
pale04380
Osteoclast differentiation
pale04510
Focal adhesion
pale04520
Adherens junction
pale04540
Gap junction
pale04550
Signaling pathways regulating pluripotency of stem cells
pale04611
Platelet activation
pale04613
Neutrophil extracellular trap formation
pale04620
Toll-like receptor signaling pathway
pale04621
NOD-like receptor signaling pathway
pale04625
C-type lectin receptor signaling pathway
pale04650
Natural killer cell mediated cytotoxicity
pale04657
IL-17 signaling pathway
pale04658
Th1 and Th2 cell differentiation
pale04659
Th17 cell differentiation
pale04660
T cell receptor signaling pathway
pale04662
B cell receptor signaling pathway
pale04664
Fc epsilon RI signaling pathway
pale04666
Fc gamma R-mediated phagocytosis
pale04668
TNF signaling pathway
pale04713
Circadian entrainment
pale04720
Long-term potentiation
pale04722
Neurotrophin signaling pathway
pale04723
Retrograde endocannabinoid signaling
pale04724
Glutamatergic synapse
pale04725
Cholinergic synapse
pale04726
Serotonergic synapse
pale04730
Long-term depression
pale04810
Regulation of actin cytoskeleton
pale04910
Insulin signaling pathway
pale04912
GnRH signaling pathway
pale04914
Progesterone-mediated oocyte maturation
pale04915
Estrogen signaling pathway
pale04916
Melanogenesis
pale04917
Prolactin signaling pathway
pale04919
Thyroid hormone signaling pathway
pale04921
Oxytocin signaling pathway
pale04926
Relaxin signaling pathway
pale04928
Parathyroid hormone synthesis, secretion and action
pale04929
GnRH secretion
pale04930
Type II diabetes mellitus
pale04933
AGE-RAGE signaling pathway in diabetic complications
pale04934
Cushing syndrome
pale04935
Growth hormone synthesis, secretion and action
pale04960
Aldosterone-regulated sodium reabsorption
pale05010
Alzheimer disease
pale05020
Prion disease
pale05022
Pathways of neurodegeneration - multiple diseases
pale05034
Alcoholism
pale05132
Salmonella infection
pale05133
Pertussis
pale05135
Yersinia infection
pale05140
Leishmaniasis
pale05142
Chagas disease
pale05145
Toxoplasmosis
pale05152
Tuberculosis
pale05160
Hepatitis C
pale05161
Hepatitis B
pale05163
Human cytomegalovirus infection
pale05164
Influenza A
pale05165
Human papillomavirus infection
pale05166
Human T-cell leukemia virus 1 infection
pale05167
Kaposi sarcoma-associated herpesvirus infection
pale05170
Human immunodeficiency virus 1 infection
pale05171
Coronavirus disease - COVID-19
pale05200
Pathways in cancer
pale05203
Viral carcinogenesis
pale05205
Proteoglycans in cancer
pale05206
MicroRNAs in cancer
pale05207
Chemical carcinogenesis - receptor activation
pale05208
Chemical carcinogenesis - reactive oxygen species
pale05210
Colorectal cancer
pale05211
Renal cell carcinoma
pale05212
Pancreatic cancer
pale05213
Endometrial cancer
pale05214
Glioma
pale05215
Prostate cancer
pale05216
Thyroid cancer
pale05218
Melanoma
pale05219
Bladder cancer
pale05220
Chronic myeloid leukemia
pale05221
Acute myeloid leukemia
pale05223
Non-small cell lung cancer
pale05224
Breast cancer
pale05225
Hepatocellular carcinoma
pale05226
Gastric cancer
pale05230
Central carbon metabolism in cancer
pale05231
Choline metabolism in cancer
pale05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pale05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102885749 (MAPK3)
04012 ErbB signaling pathway
102885749 (MAPK3)
04014 Ras signaling pathway
102885749 (MAPK3)
04015 Rap1 signaling pathway
102885749 (MAPK3)
04350 TGF-beta signaling pathway
102885749 (MAPK3)
04370 VEGF signaling pathway
102885749 (MAPK3)
04371 Apelin signaling pathway
102885749 (MAPK3)
04668 TNF signaling pathway
102885749 (MAPK3)
04066 HIF-1 signaling pathway
102885749 (MAPK3)
04068 FoxO signaling pathway
102885749 (MAPK3)
04072 Phospholipase D signaling pathway
102885749 (MAPK3)
04071 Sphingolipid signaling pathway
102885749 (MAPK3)
04024 cAMP signaling pathway
102885749 (MAPK3)
04022 cGMP-PKG signaling pathway
102885749 (MAPK3)
04151 PI3K-Akt signaling pathway
102885749 (MAPK3)
04150 mTOR signaling pathway
102885749 (MAPK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102885749 (MAPK3)
04148 Efferocytosis
102885749 (MAPK3)
09143 Cell growth and death
04114 Oocyte meiosis
102885749 (MAPK3)
04210 Apoptosis
102885749 (MAPK3)
04218 Cellular senescence
102885749 (MAPK3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102885749 (MAPK3)
04520 Adherens junction
102885749 (MAPK3)
04540 Gap junction
102885749 (MAPK3)
04550 Signaling pathways regulating pluripotency of stem cells
102885749 (MAPK3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102885749 (MAPK3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102885749 (MAPK3)
04613 Neutrophil extracellular trap formation
102885749 (MAPK3)
04620 Toll-like receptor signaling pathway
102885749 (MAPK3)
04621 NOD-like receptor signaling pathway
102885749 (MAPK3)
04625 C-type lectin receptor signaling pathway
102885749 (MAPK3)
04650 Natural killer cell mediated cytotoxicity
102885749 (MAPK3)
04660 T cell receptor signaling pathway
102885749 (MAPK3)
04658 Th1 and Th2 cell differentiation
102885749 (MAPK3)
04659 Th17 cell differentiation
102885749 (MAPK3)
04657 IL-17 signaling pathway
102885749 (MAPK3)
04662 B cell receptor signaling pathway
102885749 (MAPK3)
04664 Fc epsilon RI signaling pathway
102885749 (MAPK3)
04666 Fc gamma R-mediated phagocytosis
102885749 (MAPK3)
04062 Chemokine signaling pathway
102885749 (MAPK3)
09152 Endocrine system
04910 Insulin signaling pathway
102885749 (MAPK3)
04929 GnRH secretion
102885749 (MAPK3)
04912 GnRH signaling pathway
102885749 (MAPK3)
04915 Estrogen signaling pathway
102885749 (MAPK3)
04914 Progesterone-mediated oocyte maturation
102885749 (MAPK3)
04917 Prolactin signaling pathway
102885749 (MAPK3)
04921 Oxytocin signaling pathway
102885749 (MAPK3)
04926 Relaxin signaling pathway
102885749 (MAPK3)
04935 Growth hormone synthesis, secretion and action
102885749 (MAPK3)
04919 Thyroid hormone signaling pathway
102885749 (MAPK3)
04928 Parathyroid hormone synthesis, secretion and action
102885749 (MAPK3)
04916 Melanogenesis
102885749 (MAPK3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
102885749 (MAPK3)
04270 Vascular smooth muscle contraction
102885749 (MAPK3)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
102885749 (MAPK3)
09156 Nervous system
04724 Glutamatergic synapse
102885749 (MAPK3)
04725 Cholinergic synapse
102885749 (MAPK3)
04726 Serotonergic synapse
102885749 (MAPK3)
04720 Long-term potentiation
102885749 (MAPK3)
04730 Long-term depression
102885749 (MAPK3)
04723 Retrograde endocannabinoid signaling
102885749 (MAPK3)
04722 Neurotrophin signaling pathway
102885749 (MAPK3)
09158 Development and regeneration
04360 Axon guidance
102885749 (MAPK3)
04380 Osteoclast differentiation
102885749 (MAPK3)
09159 Environmental adaptation
04713 Circadian entrainment
102885749 (MAPK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102885749 (MAPK3)
05206 MicroRNAs in cancer
102885749 (MAPK3)
05205 Proteoglycans in cancer
102885749 (MAPK3)
05207 Chemical carcinogenesis - receptor activation
102885749 (MAPK3)
05208 Chemical carcinogenesis - reactive oxygen species
102885749 (MAPK3)
05203 Viral carcinogenesis
102885749 (MAPK3)
05230 Central carbon metabolism in cancer
102885749 (MAPK3)
05231 Choline metabolism in cancer
102885749 (MAPK3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102885749 (MAPK3)
09162 Cancer: specific types
05210 Colorectal cancer
102885749 (MAPK3)
05212 Pancreatic cancer
102885749 (MAPK3)
05225 Hepatocellular carcinoma
102885749 (MAPK3)
05226 Gastric cancer
102885749 (MAPK3)
05214 Glioma
102885749 (MAPK3)
05216 Thyroid cancer
102885749 (MAPK3)
05221 Acute myeloid leukemia
102885749 (MAPK3)
05220 Chronic myeloid leukemia
102885749 (MAPK3)
05218 Melanoma
102885749 (MAPK3)
05211 Renal cell carcinoma
102885749 (MAPK3)
05219 Bladder cancer
102885749 (MAPK3)
05215 Prostate cancer
102885749 (MAPK3)
05213 Endometrial cancer
102885749 (MAPK3)
05224 Breast cancer
102885749 (MAPK3)
05223 Non-small cell lung cancer
102885749 (MAPK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102885749 (MAPK3)
05170 Human immunodeficiency virus 1 infection
102885749 (MAPK3)
05161 Hepatitis B
102885749 (MAPK3)
05160 Hepatitis C
102885749 (MAPK3)
05171 Coronavirus disease - COVID-19
102885749 (MAPK3)
05164 Influenza A
102885749 (MAPK3)
05163 Human cytomegalovirus infection
102885749 (MAPK3)
05167 Kaposi sarcoma-associated herpesvirus infection
102885749 (MAPK3)
05165 Human papillomavirus infection
102885749 (MAPK3)
09171 Infectious disease: bacterial
05132 Salmonella infection
102885749 (MAPK3)
05135 Yersinia infection
102885749 (MAPK3)
05133 Pertussis
102885749 (MAPK3)
05152 Tuberculosis
102885749 (MAPK3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102885749 (MAPK3)
05140 Leishmaniasis
102885749 (MAPK3)
05142 Chagas disease
102885749 (MAPK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
102885749 (MAPK3)
05020 Prion disease
102885749 (MAPK3)
05022 Pathways of neurodegeneration - multiple diseases
102885749 (MAPK3)
09165 Substance dependence
05034 Alcoholism
102885749 (MAPK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102885749 (MAPK3)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102885749 (MAPK3)
04933 AGE-RAGE signaling pathway in diabetic complications
102885749 (MAPK3)
04934 Cushing syndrome
102885749 (MAPK3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102885749 (MAPK3)
01524 Platinum drug resistance
102885749 (MAPK3)
01522 Endocrine resistance
102885749 (MAPK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pale01001
]
102885749 (MAPK3)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pale03036
]
102885749 (MAPK3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pale04147
]
102885749 (MAPK3)
Enzymes [BR:
pale01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
102885749 (MAPK3)
Protein kinases [BR:
pale01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
102885749 (MAPK3)
Chromosome and associated proteins [BR:
pale03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
102885749 (MAPK3)
Exosome [BR:
pale04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
102885749 (MAPK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
Kdo
FTA2
Motif
Other DBs
NCBI-GeneID:
102885749
NCBI-ProteinID:
XP_006914289
LinkDB
All DBs
Position
Unknown
AA seq
395 aa
AA seq
DB search
MDGITHRRDERAWLREAQLSKGLGGGGGEPRGADGVGPGVSGEVEIVKGQPFDVGPRYTQ
LQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFHHENVIGIR
DILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHVCYFLYQILRGLKYIHSANVLH
RDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTK
SIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSL
PSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEE
PFTFDMELDDLPKERLKELIFQETARFQPGVLEAH
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atggacgggatcactcatcgtcgggacgagcgagcctggctcagggaggcccaactctct
aaagggctggggggcgggggcggggagccccggggagctgatggggtcggcccgggggtc
tctggggaagtggagatagtgaaggggcagccgttcgacgtgggcccgcgctacacgcaa
ctgcagtacatcggcgagggcgcctatggcatggtcagctcagcttacgaccatgtgcgc
aagacacgcgtagccatcaagaaaatcagccccttcgagcatcagacctactgccagcgc
acactgcgggagatccagatcttgctgcgcttccaccatgagaatgtcattggcatccga
gatattctgcgtgcacccaccctggaagccatgagggatgtctacattgtgcaggacctg
atggagacagacctgtacaagttgctcaaaagccagcagctgagcaacgaccatgtctgc
tacttcctctaccagatcctgcggggcctcaagtatattcactcagccaacgtactccac
cgggatttaaagccctccaacctgctcatcaacaccacctgcgaccttaagatctgcgat
tttggcctggcccggatcgccgatcctgagcatgaccacactggattcctgacagaatac
gtggccacacgctggtaccgggccccagagatcatgcttaactccaagggctacaccaag
tccatcgacatctggtctgtaggctgcattctggctgagatgctctccaaccggcccatc
ttccctggcaagcactacctggaccagctcaaccatattctgggtatcctgggctcccca
tctcaggaggacctgaattgtatcatcaacatgaaggcccgaaactacctacagtctctg
ccctccaagaccaaggtggcctgggccaagctttttcccaagtcagactccaaagccctt
gatctgctggaccggatgttgacctttaaccccaataaacggatcacagtggaagaagcc
ttggctcacccctacttggagcagtactatgacccaacagatgagccggtggctgaggaa
cctttcaccttcgacatggagctcgatgatctacccaaggagcggctgaaggagctcata
ttccaggagacagcccgcttccagcctggggtgctggaggcccactaa
DBGET
integrated database retrieval system