Physeter catodon (sperm whale): 102976909
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Entry
102976909 CDS
T06011
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01524
Platinum drug resistance
pcad04010
MAPK signaling pathway
pcad04071
Sphingolipid signaling pathway
pcad04141
Protein processing in endoplasmic reticulum
pcad04210
Apoptosis
pcad04530
Tight junction
pcad04668
TNF signaling pathway
pcad04714
Thermogenesis
pcad04722
Neurotrophin signaling pathway
pcad04932
Non-alcoholic fatty liver disease
pcad04936
Alcoholic liver disease
pcad05010
Alzheimer disease
pcad05012
Parkinson disease
pcad05014
Amyotrophic lateral sclerosis
pcad05016
Huntington disease
pcad05017
Spinocerebellar ataxia
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05208
Chemical carcinogenesis - reactive oxygen species
pcad05417
Lipid and atherosclerosis
pcad05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102976909 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102976909 (MAP3K5)
04668 TNF signaling pathway
102976909 (MAP3K5)
04071 Sphingolipid signaling pathway
102976909 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
102976909 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
102976909 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
102976909 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
102976909 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102976909 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
102976909 (MAP3K5)
05012 Parkinson disease
102976909 (MAP3K5)
05014 Amyotrophic lateral sclerosis
102976909 (MAP3K5)
05016 Huntington disease
102976909 (MAP3K5)
05017 Spinocerebellar ataxia
102976909 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
102976909 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102976909 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
102976909 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102976909 (MAP3K5)
04932 Non-alcoholic fatty liver disease
102976909 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102976909 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102976909 (MAP3K5)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
102976909 (MAP3K5)
Protein kinases [BR:
pcad01001
]
Serine/threonine kinases: STE group
STE11 family
102976909 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
102976909
NCBI-ProteinID:
XP_023978393
Ensembl:
ENSPCTG00005002829
UniProt:
A0A2Y9SIX6
LinkDB
All DBs
Position
10:27271018..27503310
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPLAEGGSYRRGGAAAAAEGEENQLSPPPPGSFWNVESAAAPGAGCP
SASAGSSATRCRGNSGGGGGRQTTVAYVINEASQGQLVVAESEALQCLRQACETVGATLE
TLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTN
SDSLQSLKEIICQKNTMCTGNYTFIPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFMDSESRDHGASWFKKAFESEPT
LQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHLRVIQASEKLFKLKTPAWYLRSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRNTEEGDCEG
DSLEYDYEYEENGDRVILGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLVASLGEFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEEQPSNQTVQ
RPHVVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIDIPGLPVCHLNSPGTNTEDSELTEWLRENGADEDTIS
RFLAEDYSLADVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQT
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccacccttggccgagggcggc
agctaccggaggggaggagcggcggcggccgccgagggcgaggagaaccagctctcgccg
ccgccaccgggcagcttctggaacgtggagagtgctgcggcccctggtgctgggtgtccc
agtgcctccgccgggagcagcgccacccggtgccggggcaactctggtggcggaggaggc
cgacagaccacggtggcatatgtcatcaacgaagcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagtgcctgcggcaggcgtgcgagacggtgggcgccaccctggag
accctgcatttcgggaaactggactttggggaaactgcggtgctggaccgtttttacaat
gcagatattgccgtggtggagatgagtgatgccttccggcagccgtctttattttaccac
cttggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgatactaat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacatttattccttacatgataactccacataacaaggtctactgctgtgatagc
agcttcatgaagggcctgacagagctcatgcagccgaactttgagctgctccttggaccc
atctgcttacctcttgtggatcgtttcattcaacttttgaaggtggcacaagcaagttcc
agccagtatttccgggaatctatactcaacgatatcaggaaagctcgtaacttatacact
ggtaaagaattggcagctgaattggcaagaattcgacagcgagtggataatattgaagtt
ctgacagcagatattgtcataaatctgttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagactttagaaaagctgccaacctttgatttggcctcccat
caccatgtgaagtttcattatgcatttgcgctgaataggagaaatctccctggagataga
gcaaaagctcttgacattatgattcccctggtgcaaagtgaagggcaagttgcttcagat
atgtattgcctcgttggtcgaatctacaaagatatgtttttggactctaatttcatggat
tctgaaagtagagaccatggagcttcttggttcaaaaaggcatttgaatctgagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcatctgggcaccagtttgaatct
tcctttgagctccgaaaagttggggtgaagctcagtagccttcttggtaaaaagggaaac
ttggaaaagctccagagctactgggaagttggatttttcctgggagcaagtgtcctggcc
aatgaccacttgagagtcattcaagcatctgaaaagctttttaaactgaagacacctgca
tggtacctcaggtctattgtagagacaattttgatatataagcattttgtgaaactgact
tcagaacagcccgtggccaagcaggaacttgtggacttctggatggatttcctggttgag
gccacaaagacagatgtcactgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcgtatttgtctatcaacaatgaagtggaggaaaagacaatatctatc
tggcacgtacttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcac
aattctgatgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccattaccgaagagaaggggagaaacacagaggaaggagattgtgaaggt
gactccctggagtatgactatgaatatgaagaaaatggtgacagagtcattttaggaaaa
ggcacttatgggatagtttatgcaggtcgagatctgagcaaccaagtcagaatcgccatt
aaggaaatcccagagagagatagcagatactcccagcccctacatgaagaaatagcactg
cataagcatctgaagcacaaaaatattgttcagtatctgggctctttcagtgagaatggt
ttcattaaaatcttcatggagcaggtcccagggggaagtctttctgctctccttcgttcc
aaatggggcccgctgaaagacaacgagcaaacaattggcttttataccaagcaaatactg
gaaggattaaaatacctccatgacaatcagatagttcaccgggatataaagggtgacaat
gtgttgattaatacctatagtggtgttctcaagatctctgatttcgggacatcaaagagg
cttgctggcataaatccatgtactgaaacttttactggtacccttcagtatatggcacca
gaaataatagataaaggaccaagaggctacgggaaagcagcagacatttggtctttggga
tgcacaatcattgaaatggccactggaaaaccacccttttatgaactgggggaaccacaa
gcagctatgttcaaggtgggaatgtttaaggtccacccggagattccagagtccatgtcg
gcagaggctaaagcgttcatactgaaatgttttgaaccagaccctgacaagagagactgt
gctaacgacttgcttatggatgaattcttaaaggtttcaagcaaaaagaaaaagacacaa
cctaagctttcagctctttcagctggatcgaatgagtatcttaggagcatctccctgcca
gtgcctgtcctggtggaggacacaagcagtagcagtgagtacggctcggtttctccagac
acggagttaaaggtggatcccttctctttcaaaacaagagccaagtcctgcggagaaaaa
gatgtcaaaggaatacggacactctttctgggcatccctgacgaaaattttgaagaccat
agcgctccaccttctcctgaagaaaaagattctggattctttatgctgaggaaggacagt
gagagacgggccacgcttcacaggatactgacggaagaccaagacaaagttgtgagaaac
ttaatggaatctttggctcagggggccgaagaacctaaactaaaatgggagcacatcaca
accctcgtcgcaagcctcggagaatttgtgaggtccactgaccggaagatcatagccacc
accctgtccaagctgaagctggagctggactttgacagccacggcattagtcaagttcag
gtggtgctcttcggctttcaagatgctgtcaataaagttcttcggaatcataatatcaag
ccacactggatgtttgccttagacagtatcatccgaaaggcggtgcagacagccattacc
attctggttccagaactgaggccacattttagccttgcatctgagagtgataccgccgat
caagaagacttggatgcagaagatgaccatgaagaacagccttcaaatcaaactgtccaa
agacctcatgtggtccttgaagatgctgtggccacctcaggggtgagcacactcagttct
actgtatcccacgactcccagagtgctcaccgatcgctgaatgtacagcttggaaggatg
aaaatagaaacaaatagattactggaagaattggttcagaaagagaaagaattacaagca
ctccttcatcaagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaatagatattcctgggttgcctgtgtgtcacctgaattctcctggcacaaatact
gaagattctgaacttactgaatggctgagagaaaatggagccgatgaagacactataagt
cggtttttggctgaggattattcactagcagatgttctctactatgttacacgtgacgat
ttaaaatgcctgagactaaggggagggatgctgtgtacgctgtggaaagccatcactgac
tttcgagacaaacagacttga
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integrated database retrieval system
