Puma concolor (puma): 112869273
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Entry
112869273 CDS
T08890
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo01521
EGFR tyrosine kinase inhibitor resistance
pcoo01522
Endocrine resistance
pcoo04012
ErbB signaling pathway
pcoo04015
Rap1 signaling pathway
pcoo04062
Chemokine signaling pathway
pcoo04137
Mitophagy - animal
pcoo04144
Endocytosis
pcoo04360
Axon guidance
pcoo04370
VEGF signaling pathway
pcoo04510
Focal adhesion
pcoo04520
Adherens junction
pcoo04530
Tight junction
pcoo04540
Gap junction
pcoo04611
Platelet activation
pcoo04613
Neutrophil extracellular trap formation
pcoo04625
C-type lectin receptor signaling pathway
pcoo04727
GABAergic synapse
pcoo04750
Inflammatory mediator regulation of TRP channels
pcoo04810
Regulation of actin cytoskeleton
pcoo04912
GnRH signaling pathway
pcoo04915
Estrogen signaling pathway
pcoo04917
Prolactin signaling pathway
pcoo04919
Thyroid hormone signaling pathway
pcoo04921
Oxytocin signaling pathway
pcoo04926
Relaxin signaling pathway
pcoo05100
Bacterial invasion of epithelial cells
pcoo05135
Yersinia infection
pcoo05152
Tuberculosis
pcoo05161
Hepatitis B
pcoo05163
Human cytomegalovirus infection
pcoo05167
Kaposi sarcoma-associated herpesvirus infection
pcoo05168
Herpes simplex virus 1 infection
pcoo05203
Viral carcinogenesis
pcoo05205
Proteoglycans in cancer
pcoo05207
Chemical carcinogenesis - receptor activation
pcoo05208
Chemical carcinogenesis - reactive oxygen species
pcoo05219
Bladder cancer
pcoo05417
Lipid and atherosclerosis
pcoo05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
112869273 (SRC)
04015 Rap1 signaling pathway
112869273 (SRC)
04370 VEGF signaling pathway
112869273 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112869273 (SRC)
04137 Mitophagy - animal
112869273 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112869273 (SRC)
04520 Adherens junction
112869273 (SRC)
04530 Tight junction
112869273 (SRC)
04540 Gap junction
112869273 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112869273 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112869273 (SRC)
04613 Neutrophil extracellular trap formation
112869273 (SRC)
04625 C-type lectin receptor signaling pathway
112869273 (SRC)
04062 Chemokine signaling pathway
112869273 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
112869273 (SRC)
04915 Estrogen signaling pathway
112869273 (SRC)
04917 Prolactin signaling pathway
112869273 (SRC)
04921 Oxytocin signaling pathway
112869273 (SRC)
04926 Relaxin signaling pathway
112869273 (SRC)
04919 Thyroid hormone signaling pathway
112869273 (SRC)
09156 Nervous system
04727 GABAergic synapse
112869273 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112869273 (SRC)
09158 Development and regeneration
04360 Axon guidance
112869273 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
112869273 (SRC)
05207 Chemical carcinogenesis - receptor activation
112869273 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
112869273 (SRC)
05203 Viral carcinogenesis
112869273 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
112869273 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
112869273 (SRC)
05168 Herpes simplex virus 1 infection
112869273 (SRC)
05163 Human cytomegalovirus infection
112869273 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
112869273 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
112869273 (SRC)
05152 Tuberculosis
112869273 (SRC)
05100 Bacterial invasion of epithelial cells
112869273 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112869273 (SRC)
05418 Fluid shear stress and atherosclerosis
112869273 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112869273 (SRC)
01522 Endocrine resistance
112869273 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112869273 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pcoo04131
]
112869273 (SRC)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112869273 (SRC)
Protein kinases [BR:
pcoo01001
]
Non-receptor tyrosine kinases
SRC family
112869273 (SRC)
Membrane trafficking [BR:
pcoo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
112869273 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
112869273 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
112869273 (SRC)
Macropinocytosis
Kinases
112869273 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH3_10
ABC1
Haspin_kinase
SH3_3
Motif
Other DBs
NCBI-GeneID:
112869273
NCBI-ProteinID:
XP_025788166
UniProt:
A0A6P6IIY4
LinkDB
All DBs
Position
Unknown
AA seq
536 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagcct
gctgagaacacccacggtggtggtgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccccagtacggccttcccctctgccgctgctgag
cccaagctgttcgggggcttcaactcctcggacacagtcacctccccgcagagggcgggg
ccgctggcgggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
actgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacagagggtgac
tggtggctggcccactcactcagcacaggacagacgggctacatccccagcaactatgtg
gcgccctctgactctatccaggccgaagagtggtactttggcaagatcaccagacgggag
tcagagaggttactgctcaatgcggaaaacccaagagggaccttcctagtgcgagaaagc
gagaccacgaaaggcgcctactgcctctccgtgtccgatttcgacaacgccaagggcctc
aatgtgaagcattacaagatccgcaagctggacagcggtggcttctacatcacctcccgc
acccagttcaacagtctgcagcagctggtggcctactactccaaacatgccgacggcctc
tgccaccgcctcaccaccgtgtgccccacgtccaagccacagactcagggcctggccaaa
gacgcctgggagatcccccgggagtccctgcggctggaggtcaagctgggccagggctgt
ttcggagaggtgtggatgggaacctggaacggaaccaccagggtggccatcaaaaccctg
aagccaggcacgatgtctccagaggcctttctgcaggaggcccaggtcatgaagaaacta
aggcacgagaaattggtgcagctgtatgccgtggtgtctgaggagcccatctacattgtc
acggagtacatgagcaaggggagtttgctggactttctcaagggggagacaggcaagtac
ctgcggctgccacagctggtggacatggctgctcagatcgcctcgggcatggcctacgtg
gagcggatgaactacgtgcaccgggacctccgtgctgccaacattctggttggagagaac
ctcgtgtgcaaagtggccgactttgggctggctcggctcatcgaagacaatgaatacacc
gcccggcaaggtgccaaattccccatcaagtggacggctccagaagcggccctgtacggc
cggttcaccatcaagtcagatgtgtggtcctttgggatcctgctgacggagctcacaaca
aagggacgggtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcgg
ggctaccggatgccctgcccgcctgagtgtcccgagtccctgcatgacctcatgtgccag
tgctggcggaaggaaccggaagagcggcccaccttcgagtacctgcaggccttcctagag
gactacttcacgtccaccgagccccagtaccagcctggagagaacctatag
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