Phascolarctos cinereus (koala): 110204990
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Entry
110204990 CDS
T05867
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01521
EGFR tyrosine kinase inhibitor resistance
pcw01522
Endocrine resistance
pcw04010
MAPK signaling pathway
pcw04012
ErbB signaling pathway
pcw04014
Ras signaling pathway
pcw04015
Rap1 signaling pathway
pcw04020
Calcium signaling pathway
pcw04066
HIF-1 signaling pathway
pcw04068
FoxO signaling pathway
pcw04072
Phospholipase D signaling pathway
pcw04144
Endocytosis
pcw04151
PI3K-Akt signaling pathway
pcw04510
Focal adhesion
pcw04520
Adherens junction
pcw04540
Gap junction
pcw04630
JAK-STAT signaling pathway
pcw04810
Regulation of actin cytoskeleton
pcw04912
GnRH signaling pathway
pcw04915
Estrogen signaling pathway
pcw04921
Oxytocin signaling pathway
pcw04926
Relaxin signaling pathway
pcw04928
Parathyroid hormone synthesis, secretion and action
pcw04934
Cushing syndrome
pcw05160
Hepatitis C
pcw05163
Human cytomegalovirus infection
pcw05165
Human papillomavirus infection
pcw05171
Coronavirus disease - COVID-19
pcw05200
Pathways in cancer
pcw05205
Proteoglycans in cancer
pcw05206
MicroRNAs in cancer
pcw05207
Chemical carcinogenesis - receptor activation
pcw05208
Chemical carcinogenesis - reactive oxygen species
pcw05210
Colorectal cancer
pcw05212
Pancreatic cancer
pcw05213
Endometrial cancer
pcw05214
Glioma
pcw05215
Prostate cancer
pcw05218
Melanoma
pcw05219
Bladder cancer
pcw05223
Non-small cell lung cancer
pcw05224
Breast cancer
pcw05225
Hepatocellular carcinoma
pcw05226
Gastric cancer
pcw05230
Central carbon metabolism in cancer
pcw05231
Choline metabolism in cancer
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110204990 (EGFR)
04012 ErbB signaling pathway
110204990 (EGFR)
04014 Ras signaling pathway
110204990 (EGFR)
04015 Rap1 signaling pathway
110204990 (EGFR)
04630 JAK-STAT signaling pathway
110204990 (EGFR)
04066 HIF-1 signaling pathway
110204990 (EGFR)
04068 FoxO signaling pathway
110204990 (EGFR)
04020 Calcium signaling pathway
110204990 (EGFR)
04072 Phospholipase D signaling pathway
110204990 (EGFR)
04151 PI3K-Akt signaling pathway
110204990 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110204990 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110204990 (EGFR)
04520 Adherens junction
110204990 (EGFR)
04540 Gap junction
110204990 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110204990 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
110204990 (EGFR)
04915 Estrogen signaling pathway
110204990 (EGFR)
04921 Oxytocin signaling pathway
110204990 (EGFR)
04926 Relaxin signaling pathway
110204990 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
110204990 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110204990 (EGFR)
05206 MicroRNAs in cancer
110204990 (EGFR)
05205 Proteoglycans in cancer
110204990 (EGFR)
05207 Chemical carcinogenesis - receptor activation
110204990 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
110204990 (EGFR)
05230 Central carbon metabolism in cancer
110204990 (EGFR)
05231 Choline metabolism in cancer
110204990 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110204990 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
110204990 (EGFR)
05212 Pancreatic cancer
110204990 (EGFR)
05225 Hepatocellular carcinoma
110204990 (EGFR)
05226 Gastric cancer
110204990 (EGFR)
05214 Glioma
110204990 (EGFR)
05218 Melanoma
110204990 (EGFR)
05219 Bladder cancer
110204990 (EGFR)
05215 Prostate cancer
110204990 (EGFR)
05213 Endometrial cancer
110204990 (EGFR)
05224 Breast cancer
110204990 (EGFR)
05223 Non-small cell lung cancer
110204990 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
110204990 (EGFR)
05171 Coronavirus disease - COVID-19
110204990 (EGFR)
05163 Human cytomegalovirus infection
110204990 (EGFR)
05165 Human papillomavirus infection
110204990 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110204990 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110204990 (EGFR)
01522 Endocrine resistance
110204990 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110204990 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcw04147
]
110204990 (EGFR)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110204990 (EGFR)
Protein kinases [BR:
pcw01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
110204990 (EGFR)
Exosome [BR:
pcw04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
110204990 (EGFR)
Exosomal proteins of pancreatic cancer cells
110204990 (EGFR)
Exosomal proteins of bladder cancer cells
110204990 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
110204990
NCBI-ProteinID:
XP_020836941
UniProt:
A0A6P5JX48
LinkDB
All DBs
Position
Unknown
AA seq
1213 aa
AA seq
DB search
MGLYGAAGAAVLVLLAGHFSLSSALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQKNYDLSFLKTIQEVAGYVLIALNAVEKIPLENLQIIRGNVLYENFYALS
VLSNYDVNKTGVRELPMRNLLEILVGGVRFNNNPTLCNVETIQWKDIVDSAYLNNITIDN
NSHPKSCEKCDSSCPNGSCWGPGPQNCQSLTKTICAQQCSGRCRGSSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPDGKYSFGATCVRKCPHNYV
VTDHGSCVRSCNAETYEVEEDGVRKCKKCEGPCSKVCNGIGIGEFKDVLSINATNIKQFQ
NCTTISGDLHILPVAFKGDSFTNTPPLDPKELNILRTVKEISGFLLIQAWPENMTDLHAF
EHLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLKEISDGDVIISKNRQLCYANTINWNKL
FGTKSQKSKITNNKDEKECRTLGHVCHELCSPDGCWGPKPSHCLSCRYVSRHKKCVEKCN
ILEGEPREYMENLKCLQCHPECLPQVMNQTCTGPGPDKCIECAHYIDGPHCVKTCPAGIM
GENDTLVWKYADANKVCQRCHPNCTYGCEGPGLEGCPTPGPKIPSIATGIVGGFLLLMVL
ILGIGLFIRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDHPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYIREHKDNIGSQYLLNWCVQIAKGMSYLEERRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIVEFSKMARDPQRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLIPQ
QGFFNSPSTSRTPLLSSLSATSNNSATVCIDRNGQICPVKEESFIQRYSSDPTTVLTEDN
VDDSFQPVPEYINQSAPKNHTGSAIQNPVYHNQPFNPDASKDSLYQNSHNSSAVDNPEYL
NTTQPNLIKKAFDGNSCWNPKANHPISLDNPDYQQDFFPQEAKPNGVFKVPAAENPEYLR
VAAQQSEFIQASA
NT seq
3642 nt
NT seq
+upstream
nt +downstream
nt
atggggctctatggggctgctggagccgctgtcctggtgctgcttgccggacacttctcc
ctgagctcggcgctggaagaaaagaaagtttgccaaggaacaagtaacaagctgacccag
ttgggtacttttgaggaccacttcctgagtctccagagaatgttcaataactgtgaggtg
gtacttggaaatttggaaatcacctatgtccaaaaaaattatgacctttccttcctaaag
accatccaggaggttgctggctatgtgctcattgctctcaatgcagtcgagaaaattcct
ttggaaaacctgcagatcatccgaggaaatgtgttgtacgaaaatttttatgccctttct
gtgctctccaactatgatgtgaataaaacaggagtgagggaactgcccatgaggaatcta
ctagaaatccttgttggtggtgttcggttcaacaataacccaaccctgtgtaatgtggag
acgatccagtggaaggatattgtggactccgcctatttaaacaatatcacaatagacaat
aacagccatcctaagagttgtgaaaagtgtgattctagttgtcccaatggaagctgttgg
ggtcctggaccacaaaattgccagagtttgacgaagaccatctgtgcccagcagtgctca
ggacggtgtcgcggtagttcccccagtgactgttgccacaaccagtgcgcagcaggttgt
actggaccccgagagagtgactgcttggtctgtcgaaagtttcgagatgaagccacatgc
aaagacacctgcccccctctgatgctatacaaccccaccacataccagatggatgtcaac
ccagacggcaaatacagctttggagccacctgtgtacgcaagtgcccacataactatgtg
gtgacagaccatggttcttgtgttcgctcctgtaatgctgagacctatgaagtggaggaa
gatggcgtccgaaaatgtaaaaagtgtgaaggtccatgtagtaaagtttgcaatggaata
ggaattggtgaatttaaagatgttctctccatcaatgccacaaacatcaaacaattccag
aattgtaccaccatcagcggcgatctgcacatcttgcctgttgcatttaaaggtgactcc
ttcacgaatactccacctttagatcccaaagaactgaatattctcaggaccgtgaaggaa
atatcaggatttttgctgattcaggcttggcctgaaaacatgactgacctccatgctttt
gaacatctggaaattatacgaggccgaacaaagcaacatggtcagttttctcttgctgtt
gttggcttggacataacttccttgggcttacgctccctcaaggaaatcagtgatggtgat
gtcatcatctcaaaaaacagacaactctgctatgcaaacacaataaactggaacaaactg
tttggaacaaaaagtcagaaaagcaaaatcacaaacaacaaagatgaaaaagagtgccgg
actctgggccatgtttgtcatgaattgtgctcacccgatggttgctggggtccaaagcca
agccactgcctgtcctgtcgctatgtgagccgtcacaagaagtgtgttgagaaatgtaac
attctagaaggagaaccaagggagtacatggagaatctgaaatgtctgcagtgccaccct
gagtgtctgcctcaggtgatgaatcaaacctgcacaggaccgggtcctgacaaatgcata
gaatgtgctcactatatagatggtccacactgtgtcaagacttgtccagctggaatcatg
ggagaaaatgataccttggtctggaaatatgctgatgcaaataaggtttgccaacgatgc
catcccaattgtacctatgggtgtgaaggtccaggtcttgaaggctgtcccacacctggc
cccaagatcccttccatagccactggaattgtgggtggctttctcttactgatggtgttg
atccttggcatcggtctcttcattagaaggcgccatattgtccgcaaacgcacgctgcgc
aggctactgcaagaaagggagctagtcgagcctctcacccccagtggagaagctcccaac
caggctcttttacggatcctaaaggagacagaatttaaaaagatcaaagtgcttggctct
ggagctttcggcacagtgtataagggactatggattccagaaggagagaaggtgaagatt
cctgttgccattaaagaattaagggaagctacttctccaaaagccaataaggaaattctt
gatgaagcctacgtgatggccagtgtggaccatccccatgtgtgccgtctcctgggaatc
tgtctcacttccacagtccaactcataacacagctcatgccattcggttgccttctggac
tacatacgggaacacaaggacaacattggctcccagtaccttctcaactggtgtgtgcag
attgccaaggggatgagttatctagaagagcgccgcttggtacaccgtgacttagcagcc
agaaatgtccttgtgaagacacctcaacatgtgaagatcacagattttgggctggcaaag
ctgcttggtgctgatgagaaagaataccatgcagaaggaggcaaggtgcctattaaatgg
atggctttggaatcgattttacaccgtatttatacccaccaaagtgacgtctggagctat
ggtgtcacagtttgggagctgatgacatttgggtccaaaccttacgatggaatccctgca
agtgaaatttcatctattttagagaaaggagaacgccttcctcagccacccatctgcacc
attgatgtctacatgatcatggtcaaatgctggatgatagatgctgacagtcgccccaag
tttcgtgagttgattgtagaattttctaaaatggcccgtgatccccagcgctaccttgtt
atacagggagatgaaagaatgcacttgccaagtcccacggactccaaattttatcgcacc
cttatggaagaggaggacatggaagatattgtagatgcagatgagtaccttattccacag
caaggattcttcaacagcccctccacatctcgcacacctctcctaagctctctgagtgct
accagcaataattctgccacagtatgcattgatagaaatgggcagatttgccctgtgaag
gaagaaagctttatccagagatacagttctgatcccactactgtcttaactgaagacaat
gtggatgatagcttccagcctgtaccagaatatataaaccagtcggctcctaaaaaccac
acgggttctgccatccagaaccctgtctatcacaaccagcctttcaacccagatgcctct
aaagactctctgtaccaaaactcacacaacagcagtgcggtggacaaccctgagtatctc
aacacaacccagcccaacctgatcaaaaaagccttcgacggcaattcctgctggaacccg
aaagccaaccacccaatcagtctggacaaccctgactaccagcaggacttcttcccccag
gaagccaagccaaatggggtttttaaagttcctgccgcagaaaatcctgagtacctcagg
gtagcagcacaacaaagtgaattcattcaagcttcagcatga
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integrated database retrieval system
