KEGG   Phyllostomus discolor (pale spear-nosed bat): 114506489
Entry
114506489         CDS       T07739                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521  EGFR tyrosine kinase inhibitor resistance
pdic01522  Endocrine resistance
pdic04012  ErbB signaling pathway
pdic04015  Rap1 signaling pathway
pdic04062  Chemokine signaling pathway
pdic04137  Mitophagy - animal
pdic04144  Endocytosis
pdic04360  Axon guidance
pdic04370  VEGF signaling pathway
pdic04510  Focal adhesion
pdic04520  Adherens junction
pdic04530  Tight junction
pdic04540  Gap junction
pdic04611  Platelet activation
pdic04613  Neutrophil extracellular trap formation
pdic04625  C-type lectin receptor signaling pathway
pdic04727  GABAergic synapse
pdic04750  Inflammatory mediator regulation of TRP channels
pdic04810  Regulation of actin cytoskeleton
pdic04912  GnRH signaling pathway
pdic04915  Estrogen signaling pathway
pdic04917  Prolactin signaling pathway
pdic04919  Thyroid hormone signaling pathway
pdic04921  Oxytocin signaling pathway
pdic04926  Relaxin signaling pathway
pdic05100  Bacterial invasion of epithelial cells
pdic05135  Yersinia infection
pdic05152  Tuberculosis
pdic05161  Hepatitis B
pdic05163  Human cytomegalovirus infection
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05168  Herpes simplex virus 1 infection
pdic05203  Viral carcinogenesis
pdic05205  Proteoglycans in cancer
pdic05207  Chemical carcinogenesis - receptor activation
pdic05208  Chemical carcinogenesis - reactive oxygen species
pdic05219  Bladder cancer
pdic05417  Lipid and atherosclerosis
pdic05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    114506489 (SRC)
   04015 Rap1 signaling pathway
    114506489 (SRC)
   04370 VEGF signaling pathway
    114506489 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    114506489 (SRC)
   04137 Mitophagy - animal
    114506489 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114506489 (SRC)
   04520 Adherens junction
    114506489 (SRC)
   04530 Tight junction
    114506489 (SRC)
   04540 Gap junction
    114506489 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    114506489 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    114506489 (SRC)
   04613 Neutrophil extracellular trap formation
    114506489 (SRC)
   04625 C-type lectin receptor signaling pathway
    114506489 (SRC)
   04062 Chemokine signaling pathway
    114506489 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    114506489 (SRC)
   04915 Estrogen signaling pathway
    114506489 (SRC)
   04917 Prolactin signaling pathway
    114506489 (SRC)
   04921 Oxytocin signaling pathway
    114506489 (SRC)
   04926 Relaxin signaling pathway
    114506489 (SRC)
   04919 Thyroid hormone signaling pathway
    114506489 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    114506489 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114506489 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    114506489 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    114506489 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    114506489 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    114506489 (SRC)
   05203 Viral carcinogenesis
    114506489 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    114506489 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    114506489 (SRC)
   05168 Herpes simplex virus 1 infection
    114506489 (SRC)
   05163 Human cytomegalovirus infection
    114506489 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114506489 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    114506489 (SRC)
   05152 Tuberculosis
    114506489 (SRC)
   05100 Bacterial invasion of epithelial cells
    114506489 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114506489 (SRC)
   05418 Fluid shear stress and atherosclerosis
    114506489 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    114506489 (SRC)
   01522 Endocrine resistance
    114506489 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114506489 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pdic04131]
    114506489 (SRC)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     114506489 (SRC)
Protein kinases [BR:pdic01001]
 Non-receptor tyrosine kinases
  SRC family
   114506489 (SRC)
Membrane trafficking [BR:pdic04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    114506489 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    114506489 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    114506489 (SRC)
  Macropinocytosis
   Kinases
    114506489 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 114506489
NCBI-ProteinID: XP_028380051
EnsemblRapid: ENSPDIG00005018068
UniProt: A0A6J2MKZ7
LinkDB
Position
9:88679493..88734382
AA seq 543 aa
MGSNKSKPKDASQRRRSLEPAENTHGGGSGGAFPTSQTPSKPASADGHRGPNTAFSPAAA
EPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRK
VDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRG
TFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYY
SKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT
RVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFL
KGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARL
IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE
VLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPG
ENL
NT seq 1632 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgaagcctggagcct
gctgagaacacccatggtggcggcagcgggggtgccttccccacctcccagacgcccagc
aagccggcctccgccgacggccaccgaggccccaacacggcgttctcccctgcggccgct
gagcccaagctgttcggcggcttcaactcctcagacacagtcacctccccgcagagggcg
gggcccctggctggtggagtgaccacctttgtggccctctatgactatgagtcccgcacg
gagaccgacctgtccttcaagaaaggggagaggctgcagatcgtcaacaacacgaggaag
gtggatgtcagagagggagactggtggctggcccactcactcagcacgggacagactggc
tacatccccagcaactacgtggcgccctccgactccatccaggctgaggagtggtacttt
ggcaaaatcacgagacgggagtcagaacggttactgctcaatgcagagaacccgaggggt
accttcctggtgcgagaaagcgagaccacgaaaggtgcctactgcctctcagtgtccgac
ttcgacaacgccaagggcctcaatgtgaagcactataagatccgcaagctggacagcggc
ggcttctacatcacctctcgcacccagttcaacagcctgcagcagctcgtagcctactac
tccaagcatgctgacggcctgtgtcaccgactcaccactgtgtgccccacatccaagccg
cagactcagggcctggccaaggacgcctgggagatcccccgggagtcgctgcggctggag
gtcaagctgggccagggctgcttcggagaggtgtggatgggaacctggaatggcaccacc
agagtggccatcaaaaccctgaagccgggcacgatgtctccagaggccttcctgcaggag
gcccaggtcatgaagaaactgaggcacgagaagctggtgcagctgtacgcggtggtgtct
gaggagcccatctacatcgtcacggagtacatgagcaaggggagtttgctggactttctc
aagggggagacaggcaagtacctgcggctgcctcaactggtggacatggcagctcagatc
gcctcaggcatggcgtatgtggagcggatgaattacgtccaccgggacctgcgtgcggcc
aacatcctggtgggagagaacctcgtgtgcaaagtggccgacttcggcctggctcggctc
atcgaggacaacgagtacacggcccggcaaggcgccaaattccccatcaagtggacagct
ccagaagccgcactctacggccggttcaccatcaagtcagacgtgtggtctttcgggatc
ctgctgacggagctcaccacaaaggggcgggtgccctaccccgggatggtaaaccgtgag
gtgctggaccaggtggagcggggctaccggatgccctgtccccccgagtgtcccgagtcc
ctgcacgacctcatgtgccagtgctggcggaaggagccggaggagcgacccaccttcgaa
tacctgcaggccttcctggaggactatttcacgtccacggagccccagtaccagcctgga
gagaacctatag

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