Parascardovia denticolens: PSDT_0261
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Entry
PSDT_0261 CDS
T03978
Name
(GenBank) D-alanine-D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
pdo
Parascardovia denticolens
Pathway
pdo00470
D-Amino acid metabolism
pdo00550
Peptidoglycan biosynthesis
pdo01100
Metabolic pathways
pdo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pdo00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
PSDT_0261
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PSDT_0261
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PSDT_0261
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
pdo01011
]
PSDT_0261
Enzymes [BR:
pdo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
PSDT_0261
Peptidoglycan biosynthesis and degradation proteins [BR:
pdo01011
]
Precursor biosynthesis
Amino acid ligase
PSDT_0261
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
CPSase_L_D2
Motif
Other DBs
NCBI-ProteinID:
BAR04780
UniProt:
E6K1U0
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All DBs
Position
311532..312749
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AA seq
405 aa
AA seq
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MEKSDMAESRPAENTNKSAETPSASGRKRIVVLYGGRADEHPISCISAGSVLREWDQEKF
EAVPIGITKEGVWIVDGVDPRQWELGAQLPEVKEVPGSRRVVLDVSAGGNGFLARDGRTG
AVESLGHVDAVFPVLHGPYGEDGTIQGLLEMMGLPYVGCGVLASAACMDKHYTKVLLKAA
GIPVAPGITVDTRSYDSAQGFDPQGKVLCDLVDEAGLRYPLFVKPSRAGSSFGVTKVDYK
ADATERQADLAAAVHEAARHDWRVLVEEGIKAREIECAVLAPRHGDKPRTSWPGEIVLDE
PGNGAFYDFDSKYMDSSASHVEVPAKLPQETLQEVRRVAARAFIAVDGDGLSRVDTFVTE
EGTVIVNEINTLPGFTPISMYSKAWEATGVSYRELITTLIEGILD
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
atggaaaagagcgacatggctgaatcacgaccagcagaaaacaccaacaagagcgccgag
accccatccgcctcagggcggaagagaatcgtcgtcctctacgggggccgggcggacgag
caccccatctcctgcatctccgccgggtcggtcctgcgtgagtgggaccaggagaagttc
gaggccgtccccatcggcatcaccaaggagggggtctggatcgtcgacggggtggacccc
cgtcagtgggagcttggcgctcagctgccggaagtgaaagaggtccctggctcccgccgg
gtggtcctggacgtgtccgccggagggaatggtttcctggcccgcgatgggcggaccgga
gccgtggaatcccttggccatgtggacgccgttttccccgtccttcatggcccttatggc
gaagacgggaccatccaaggcctgttggagatgatgggcctgccttatgtcggctgcggg
gttctggcttccgccgcttgcatggataagcattatacaaaagtcctgctcaaggcggcc
ggcattccggtggcgcctggcatcacggtggacacccgttcctacgattcggcccaaggc
ttcgaccctcagggcaaggttctgtgcgacttggtggatgaggcgggcctgcgttatccc
cttttcgtcaagccatcccgggccggctcgtccttcggcgtgaccaaggtggattataag
gctgatgcgactgagcggcaggcggatttggccgccgccgtccatgaagccgcccggcat
gattggcgggttttggtggaagaggggatcaaggctcgggagatcgaatgcgcggtcctg
gctccccggcacggggacaaaccccggacctcctggcctggcgagatcgtcctggacgag
cccgggaacggcgctttctacgatttcgacagcaagtacatggactcctcggcctcccat
gtggaggtccccgccaagcttccccaagagaccctgcaggaagtccgccgcgttgccgcc
cgggctttcatcgccgtggacggggacgggctttcccgggtggacactttcgtgaccgag
gaagggaccgtgatcgtcaacgaaatcaacaccttgcctggtttcacccccatctccatg
tattccaaggcctgggaggcgacgggcgtgtcgtatcgggagctgatcaccactttgatc
gaagggatcctcgactga
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