Propionibacterium freudenreichii subsp. freudenreichii DSM 20271: RM25_0649
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Entry
RM25_0649 CDS
T03860
Name
(GenBank) Isocitrate dehydrogenase [NADP]
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pfre
Propionibacterium freudenreichii subsp. freudenreichii DSM 20271
Pathway
pfre00020
Citrate cycle (TCA cycle)
pfre00480
Glutathione metabolism
pfre01100
Metabolic pathways
pfre01110
Biosynthesis of secondary metabolites
pfre01120
Microbial metabolism in diverse environments
pfre01200
Carbon metabolism
pfre01210
2-Oxocarboxylic acid metabolism
pfre01230
Biosynthesis of amino acids
Module
pfre_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pfre_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pfre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
RM25_0649
09106 Metabolism of other amino acids
00480 Glutathione metabolism
RM25_0649
Enzymes [BR:
pfre01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
RM25_0649
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
AJQ90376
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Position
758905..760122
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AA seq
405 aa
AA seq
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MAKIKVEGTVVELDGDEMTRIIWKLIKDELILPYLDINLDYYDLGIEHRDATDDQVTVDA
ANAIKKHGVGVKCATITPDEARVKEFGLKKMWRSPNGTIRNILGGVIFREPIVISNIPRL
VPGWKKPIVIGRHAFGDQYRATDVKLPGAGTVTLTYTPDDGSEPMEMEVVKMPEAGGVAM
GMYNFNKSIEDFARASFNYGLNRHYPVYLSTKNTILKAYDGQFKDIFARIFEDEYKERFD
AAGLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLLSPDG
KTMEAEAAHGTVTRHYRKYQAGEETSTNPIASVFAWTGGLRHRGELDGTPGLVAFADTLE
NVCVKTVESGRMTKDLASLVGGDQGYLNTEDFMKALSDGLAEALR
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
atggccaaaatcaaggtggaaggcactgtcgtcgagctcgatggcgacgagatgacacgc
atcatctggaagctcatcaaggacgagctgatcctcccttacctggacatcaacctcgac
tactacgaccttggtatcgagcatcgcgacgccaccgacgaccaggtgacggtggacgcc
gcgaatgccatcaagaagcacggtgtgggcgtgaaatgcgccaccatcacgcccgatgaa
gcgcgtgtgaaggaattcggcctcaagaagatgtggcgctcgcccaatggcaccatccgc
aacatcctcggcggcgtcatcttccgcgagcccatcgtgatctccaacatcccccgactg
gtgcccggctggaagaagcccatcgtcatcgggcgccacgccttcggcgaccagtaccgc
gccaccgacgtgaagctgcccggtgcgggcaccgtcacgctcacctacacccccgacgac
ggctccgagcccatggagatggaggtcgtgaagatgcccgaggccggcggtgtggccatg
ggcatgtacaacttcaacaagtcgatcgaggatttcgcccgcgcgagcttcaactacggg
ctcaatcggcactacccggtctacctgtcgacgaagaacacgatcctcaaggcctacgac
ggccagttcaaggacatcttcgcgcgcatcttcgaggacgagtacaaggagcgcttcgac
gctgccggactcacctacgagcaccgcctgatcgacgacatggtcgcctcggccctcaag
tgggagggcggctatgtgtgggcctgcaagaactacgacggcgacgtgcagtcggacatc
gtggcgcagggcttcggctcgctgggcctcatgacgtcggtgctgctcagccccgacggc
aagaccatggaggccgaggcggcccacggcaccgtgacccgccactaccgcaagtaccag
gccggggaggagaccagcacgaacccgatcgcgtcggtgttcgcctggaccggtggcctg
cgccatcgtggcgagcttgatgggacccccgggttggtcgccttcgccgacaccctggag
aacgtctgcgtgaagacggtcgagagcggccggatgaccaaggacctcgcctcgttggtc
gggggcgatcagggctatctcaacaccgaggacttcatgaaggccctgtccgacggcctg
gccgaggcgctgcgctga
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