Pyrococcus furiosus DSM 3638: PF0940
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Entry
PF0940 CDS
T00075
Name
(GenBank) 3-isopropylmalate dehydrogenase 2
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
pfu
Pyrococcus furiosus DSM 3638
Pathway
pfu00290
Valine, leucine and isoleucine biosynthesis
pfu00660
C5-Branched dibasic acid metabolism
pfu01100
Metabolic pathways
pfu01110
Biosynthesis of secondary metabolites
pfu01210
2-Oxocarboxylic acid metabolism
pfu01230
Biosynthesis of amino acids
Module
pfu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pfu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PF0940
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PF0940
Enzymes [BR:
pfu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
PF0940
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
AAL81064
UniProt:
Q8U299
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Position
904320..905387
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AA seq
355 aa
AA seq
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MIKIAVIPGDGIGKEVVAEGLKVLRKIEELSNVKFDFQEYPFGAEHYLKTGETLPDWALE
EFRHFDAIYFGAIGDPRVKPGILEHGILLKLRFSLDLYVNLRPVKLYHPKLTPLKGKEKI
DMVFIRENTEGLYAGAGGFLRKGTPHEVAIQEMINTRFGVERTIRFAFEYAKTKGRKKVT
LVDKANVLTYAHDLWQRVFKEVASEYQEIETDHYYVDAMAMKMIRSPEIFEVVVTPNMFG
DILTDLGAEIVGGLGLAASGNINPRGVSMFEPVHGSAPDIAGKGIANPLAAILTAALMLE
HLGLDREASLVEKAVAKTIEENKVTPDLGGELKTSEVGNEVVKNLEVLWDEGEES
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
atgataaagatagctgtgatcccaggtgatgggataggaaaggaggtagtggctgagggg
ctaaaggttcttcgcaaaatagaggagctgagcaacgttaagttcgactttcaagagtat
ccattcggagcagaacattacttgaaaactggagaaacccttccagactgggctcttgag
gagtttagacactttgatgcaatttactttggagcaattggggatccaagggtaaagccg
ggaattctagaacacggaattctacttaagctcagattttccctagacctttacgtaaac
ttaagacctgtaaagttataccacccaaaactaactccgctaaagggaaaggaaaagatt
gacatggtgttcataagggaaaacactgagggcctatatgcaggagcgggtggttttctt
aggaaggggacccctcatgaggtcgctattcaagaaatgataaatactaggtttggagtc
gagagaaccattaggtttgcctttgaatatgcaaagactaaggggagaaaaaaggtaact
ctagtagataaggccaacgttcttacctatgctcacgatctctggcagagagtgtttaag
gaagttgcttcggaataccaggaaatagagactgaccactactatgttgatgctatggca
atgaaaatgatccgttctccagagatcttcgaagtagttgtaactccaaacatgtttgga
gacattctcactgacttgggagcagagattgtgggaggattaggattagcagcttctgga
aatatcaatccaaggggagtttccatgtttgagccagtccacggttctgccccagacatt
gcaggaaagggcattgcaaatccactagctgcgattttaacagcagctctaatgcttgag
cacctgggattggacagggaagcctcacttgtggaaaaggccgttgcgaagacaatagaa
gaaaacaaagtaacaccagacttgggaggagagttgaagactagcgaagttggtaatgaa
gttgtgaaaaatttagaggtgttatgggatgagggagaggagagttga
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