Phyllostomus hastatus (greater spear-nosed bat): 123824609
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Entry
123824609 CDS
T07912
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00020
Citrate cycle (TCA cycle)
phas00190
Oxidative phosphorylation
phas01100
Metabolic pathways
phas01200
Carbon metabolism
phas04714
Thermogenesis
phas04932
Non-alcoholic fatty liver disease
phas05010
Alzheimer disease
phas05012
Parkinson disease
phas05014
Amyotrophic lateral sclerosis
phas05016
Huntington disease
phas05020
Prion disease
phas05022
Pathways of neurodegeneration - multiple diseases
phas05208
Chemical carcinogenesis - reactive oxygen species
phas05415
Diabetic cardiomyopathy
Module
phas_M00009
Citrate cycle (TCA cycle, Krebs cycle)
phas_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
phas_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
123824609 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
123824609 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
123824609 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
123824609 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
123824609 (SDHA)
05012 Parkinson disease
123824609 (SDHA)
05014 Amyotrophic lateral sclerosis
123824609 (SDHA)
05016 Huntington disease
123824609 (SDHA)
05020 Prion disease
123824609 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
123824609 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123824609 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123824609 (SDHA)
Enzymes [BR:
phas01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
123824609 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Pyr_redox_2
Thi4
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
123824609
NCBI-ProteinID:
XP_045703819
LinkDB
All DBs
Position
Unknown
AA seq
664 aa
AA seq
DB search
MSGVRVVSQLLRARRLALNGARPAAVQAGPRGFHFTVDGNKRSSAKVSDAISTQYPVVDH
EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR
WHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKF
GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE
DGSIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI
YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE
KDHVYLQLHHLPPEQLAIRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ
VLRHVNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDK
VPPIKANAGEESVTNLDKLRFADGSIRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKIS
QLYGDLKHVKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR
VDEYDYSKPIQGQQKKPFEQHWRKHTLSYVDIQTGKVSLEYRPVIDRTLNESDCATVPPA
IRSY
NT seq
1995 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggggttcgggttgtgtcgcagctgctgcgcgccaggcgcttggcgctgaacggg
gcgcggccggcagcagtgcaggcgggaccccgcggttttcacttcactgtggatgggaat
aagaggtcatctgctaaagtttcagatgcaatttctacacagtacccagtagtggatcat
gaatttgatgcagtggtggttggcgctggaggggcaggcttgcgagctgcatttggcctc
tctgaggcagggtttaacacggcctgtgttacaaagctcttccccaccaggtcccacact
gtggcagcccagggaggaatcaatgctgctctggggaacatggaggaggacaactggagg
tggcacttctatgacactgtgaagggctctgactggctgggggaccaggatgccatccac
tacatgacagagcaggcccccgcctctgtggttgagctagagaattacggcatgccattt
agcagaaccgaggatgggaagatatatcagcgggcctttggcggacaaagcctcaagttt
gggaaaggcgggcaggcccatcggtgctgctgcgtggctgaccgcaccggccactcactg
ctacatacgttgtatggaaggtctctgcggtatgataccagctattttgtagagtatttt
gccttggatctcctgatggaaaatggggagtgtcgtggtgtcatcgcactgtgcatagaa
gacgggtccatacatcgcataagagcaaagaacactgtgattgctactggaggctacggg
cgcacctacttcagctgcacgtctgcccacaccagcaccggcgatggcaccgccatgatc
accagggccggcctcccctgccaggacttggagttcgttcagttccaccccacaggcata
tacggtgccggttgtctcatcacggaaggatgccgtggagaaggtggaattctcattaac
agtcaaggcgagaggttcatggagcgatatgccccagtcgcaaaggacctggcctccaga
gacgtcgtttctcggtccatgactctggaaatccgtgaaggaagaggctgtggcccggag
aaagatcacgtctacctgcagttgcaccacctgcccccggagcagctggccatccgcctg
cctggcatttcggagacggccatgatctttgcgggtgtggacgtcaccaaggagccgatc
cctgtccttcccactgtgcattataacatgggcggcattcccaccaactacaaggggcag
gttctgaggcatgtgaacggccaggaccaggtcgtgcccggcctgtacgcctgtggggag
gctgcctgcgcttccgtgcatggtgccaaccgtcttggggcaaactcacttttggacttg
gtcgtctttggccgggcatgtgccctgagtatcgcagagtcctgtagacccggagataaa
gttccccctattaaagcaaatgctggagaagaatctgtcacgaatcttgacaaattgaga
tttgctgatggaagcataagaacatcagaattacgactcaacatgcagaagtcaatgcag
aatcatgctgcagtgttccgtgtgggcagcgtcttacaggaaggctgtgagaaaatcagc
cagctctatggggacctgaagcacgtgaagacctttgacagaggaatggtctggaacact
gacctggtagagaccttggagctgcagaacctgatgctctgcgcacttcagaccatttat
ggagcagaggccaggaaggagtcccgtggtgcccatgcccgggaagactacaaggtgcgg
gttgatgagtatgactattccaagcccatccaggggcagcagaagaagccatttgagcag
cactggaggaagcacaccctttcctatgttgatatccagactgggaaggtctcgctggaa
tacagacctgtgatcgacagaactttaaatgagtctgactgtgccacagtgcccccagcc
attcgctcctactga
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