Paramormyrops kingsleyae: 111853401
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Entry
111853401 CDS
T05788
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
pki
Paramormyrops kingsleyae
Brite
KEGG Orthology (KO) [BR:
pki00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pki01001
]
111853401 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pki04131
]
111853401 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pki04147
]
111853401 (lrrk2)
Enzymes [BR:
pki01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
111853401 (lrrk2)
Protein kinases [BR:
pki01001
]
Serine/threonine kinases: TKL group
LRRK family
111853401 (lrrk2)
Membrane trafficking [BR:
pki04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
111853401 (lrrk2)
Exosome [BR:
pki04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
111853401 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
WD40_2
Gtr1_RagA
Ank_2
Arf
G-alpha
Kdo
nSTAND3
Ank_4
PduV-EutP
SRPRB
Motif
Other DBs
NCBI-GeneID:
111853401
NCBI-ProteinID:
XP_023685998
Ensembl:
ENSPKIG00000013223
LinkDB
All DBs
Position
Unknown
AA seq
2514 aa
AA seq
DB search
MGDDGKLEEKVIKLTVRLKSLQEGKQLDTLVQIMDDLRCLADAQHCAAELFEDKDVHLPL
MVVLTSYMDSRRVQQVGLLLLCRLIEICPSTLDKLIGPVIEAGEWEVLAVHRQILKVLSV
HHEHSQLMALGLQVLAYILASDAIMLMVLEDDMDVFDLVVSAMTRFQTSGEIQFYGCKSL
QLLLEHVPEEHLVEFIEKEDHIIVLKAARLFRDQENVLLQALRVLYPLAGPASNVEILMS
GNERCYGVISQAMESFQHNQALQEIGCCLFQKFTSESYYSILVLNCVHRVIVRACMMYPE
NTTLQASGLSCLAALTKTVFLSTEMEGGKGEAEEREEPSWFGICCSALELHTSSAQVQES
ACRAVNSLLLYDRRIQQILRDVDGRTPIHRQIMAAILLHSSSLDVFQAATSALESLIDHD
SKVRALLLSSGIHINVVEMMKKHSSSPEVAESACKLLHQLFQGRTAGLDELIMAMCEILK
AMKVHNLLPNIQLEAMRASLTFLNPDRSLKEHGISLRDPDAVDISLKVLKNQCLVEGAHA
VYLEALNRFIGLLDVQLYGLRVLSALVDSSGAMDLMCQQGAIDTVLHTLQMYREEREIHY
WGLNLLHELIAKKKLSSMMMPVLASVVVDSVRRHQGDAEVHLKGFQVALKLLDVFPAAAS
KMETEDFDRVIFHHLSRRPSEQRADPVHRLSCLCLSKMAANSDITYIMLEKACVDGDITM
VDCLIRLGADVNKKTRTESLIYQVCERGEHLQLLELLLNCGVHEQHLRSALGAGIRRWAG
PVITLLLAKLGLDLNNSALCLGGFRLGRIEAAWLSPLFERRAPSLGRRTSKGMSLARVIL
SYQRRKAKVSSSRVVNEVCSSGYLSDESEDLSLFSAMDGCVNANSDMESDGSDGTSNIKS
KFPSDTFEESNGQHRISEVSSADSDQSVPSHRRFSKASPRQKGNCSPVFGGMDCTSPLGG
DREHIRLLDLSGNELDSLSCLMGDSVTLQHLEHVVRLELSQNNLVEFPELLCQSLRNLTR
LDLHGNHLKSFPAGLLGLPSLSVLNVSRNCVGPQLCLPPAVRCPSMRHFNLSFNHIAVFP
DLLGQSLEMLEDLLLEGNRLTVLSGPLLLPEMRLLDISRNSIERICQDALTSCLKLETLN
ASMNKLSCFSSLPSKLTTLKLADNNFTCVPEVILQLPHLRSLDMRNSSISVLPGPVAWTS
VNLSELIFSHNRIALLDISEPVYKWARLEKLHLAGNMLTEIPSEIGLLENLTSLDVSRNE
GLRSFPDEMGKLSRLWDLPLDGLRLNMNLKHIGNKTKDIVRFLQQRLKKAAPYFRMKLIM
VGNSRSGKTTLVQQLMKLRRSQWFADQLSEAIDVKDWSIRVRDKRNIVLNVWDFSGGEKF
SSSQCHFMSQRAMYIVVFNLSKGPAEVEALKPWLFNIKAIAPLSPVILVGTHADVCEDHQ
LQACLAKIKGELLLHQGFPAIRDYHMVNACEDSDPMSRLRKAVIREATGFKIQGQPVIGQ
LIPDSYLELERRLLQERARTAHDFPVLRHQHLLDIVQENQLQLDESELAHAVHFLSEAGV
LLHFVDPALQLADLYFIKPQWLCSIVSQTSPLKCACRSEQPKGIVRHSVAEKFLLESRCF
PKRYLAQYLKLLEKFQIALPFGEDQLLIPSSLPHRRPMIELPHCENSEVVVRLYEMPYFP
MDFWSRHINRLLEVSSSLLNAKEKALRPNLVCWRTGIHLNWSPEAYCLVESTSWENAPQS
FVKITVPCCRKGHILLGQVVDHIDSLLEEWFPGLLTTDIHGSGEMLLKKWVLYSFEDGQE
WSKMLLEDLLTQIKEGYLLTNPSDPRSTVPISQIAPDLILRDLPASMMLNTEELEIDLSN
EYLLGDGGFGSVYRAVYKNEEVAVKIFNKHASAMHILRQLRQELAVLGRLHHPSLVSLLA
AGTSPPLLVMELAPCGSLDSLFQHENGNLNRKLQHRIALQVADGLRFLHASMIIYRDLKP
HNILLFNLKTDSEIIAKITDYGIAQYCCSMGVRTSEGTPGFRAPEVARGNVIYNQQADVF
SFGLLMYDLLTCGERMFDGMKFPSEFDEVAVQGKLPDPVKHYGCSPWPLFEDLMKHCMKE
NPQERPSASEVFDKLNSGEMLCLMRRVDVCRVPNAECFAVARGGDAGLCVSVGGGSSSQR
RGCITSVVLSSGKLTAQEIDSSPVLCLVTVRVPEESSDWLVAGTQAGSLIVINTADMSVL
HGLQRVTDAVTSLFFHCDPEHRHKRSHLLVGTADGVLAVYDESEIQYDNGQPLKTLHIGT
INTPILSLGQSACPLDGTTIWAGCGTQVLGFNADYDILKTIETKLNCFNQWGSETNISRL
AVDKHIYVSKVRTHTVEVWDRKSERMSNLIDCAQILRQRLRVSYAERELDTGISWASVKA
LLIQHNTSLWIGTRGGHVILMDLLTCLPLQVIGHLCQSVRSMMLVHSEALNPRNVVLVLG
RSSRARREKARMDYEDDSTLLVWNSTQPQEVRDLKKHCDMRMEIADKMRTPRNT
NT seq
7545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgacgacggcaaactggaagaaaaggtgatcaaactaaccgtaagactgaaaagt
ttgcaagaggggaaacagctggacaccctggtgcagatcatggacgatttgcgctgcctg
gccgacgctcaacattgcgccgcggagctgtttgaagataaggacgtccatctgcctttg
atggtagtactgacgtcgtacatggacagccggagagtgcagcaggtggggctgttgcta
ctttgccgtctgatagaaatctgcccctccactctggacaagttaattggacctgtgata
gaggcgggggaatgggaagtactggcagtacatcgacagattctcaaggtcctctctgtg
catcacgagcacagccagctgatggccctggggctccaagtactggcgtacatccttgcc
tcagatgccataatgctgatggtcctggaggatgacatggacgtctttgacctggtggtc
agtgcgatgacacgtttccaaaccagtggagaaatccagttttacggctgcaagtccctg
cagctgcttctggagcacgttccagaggagcacctagtggaatttatagagaaggaggac
cacatcatagtcctgaaggctgcccgcttgttcagagatcaagagaatgtgcttctacag
gcccttagggtgttgtacccactggctggtccagctagcaatgtggagatcttgatgtca
ggaaatgagagatgctacggtgtcatcagtcaggctatggagtctttccaacacaatcaa
gcattgcaagagatcggctgctgccttttccagaaattcacgtcagagagctactacagc
atcctggtgctgaattgcgtgcacagggtcattgtaagagcatgtatgatgtatccagag
aatactacacttcaagcatctggtctctcttgcttggctgccctcaccaaaacggttttc
ttaagtacggaaatggagggtggaaaaggggaggcagaggagcgtgaggagccgagctgg
tttgggatctgctgcagcgccctggagctccacacctccagcgcccaggtgcaggagtct
gcatgcagagcagtgaacagtctgctgctgtacgaccgcagaatccagcagattctcagg
gatgttgacgggaggactcctatccacaggcagattatggctgccattcttctgcattca
tcctccttggatgttttccaagcagcgaccagtgcacttgagagtctcatagaccacgac
agtaaagttcgagctcttttgctgtccagtgggatccacatcaacgttgtggagatgatg
aaaaaacacagttcctctcctgaggtagcagaaagcgcatgtaagttactacatcaactg
ttccagggaaggacggccggtttggatgagctgattatggccatgtgtgagatcctgaag
gccatgaaggttcacaacctcctgcccaacatccagctagaagccatgagagccagcctg
acctttctcaatcccgacaggagcctgaaggagcacggtatctcgttgagggacccagat
gctgtggacatctcactaaaggtgctgaagaaccagtgtttggtggagggtgcacatgct
gtgtacctggaagccttgaataggttcatcggcttgctggatgttcagctgtatggtctg
agagttctgtccgctctggttgactcctctggcgcaatggatctgatgtgtcagcagggg
gcgatagatactgtgttgcacacgctgcagatgtaccgtgaggaaagagaaatccattac
tggggactgaacctgctacatgagctcattgcaaagaagaagctgtccagcatgatgatg
ccagtcctggcttcggttgtggtcgactctgtgagacgacatcagggggatgcagaggtg
catttgaaggggtttcaggtggctctgaagctgctggacgtgttcccagcagcagccagc
aagatggagacggaggacttcgacagagtgatctttcaccatctctcacggcgtccttcc
gagcagcgagcggatccagttcacagactgagctgcctctgcctctccaagatggccgct
aacagtgacatcacctacatcatgctggaaaaggcctgcgtcgacggtgacatcacaatg
gtggactgtctgatacggctgggagccgatgtcaataagaagacgaggacggagtctctt
atctatcaggtctgcgagcgaggggagcacctgcagctgctggagctgctgctgaactgc
ggcgtccacgagcagcatctgcgcagcgccctcggcgccggcatccgcaggtgggccggc
cctgtcatcactctgctcctggccaagctggggctcgacctgaacaacagcgccctctgt
ctgggcggcttccgcctgggccgcatcgaggccgcctggctgagtccgctgttcgagcgc
agagctccaagcctcgggagaaggaccagtaaagggatgtcactggctagagtgattctg
tcctaccagaggagaaaggccaaagtcagctcttccagggtggtgaatgaagtttgttcc
tcaggatacctgtctgatgaaagtgaagatctcagcctcttctctgccatggacggctgt
gtcaacgcaaattccgacatggagagtgacggaagtgatgggacctcaaacataaagagc
aaatttccatctgacacgtttgaagagagtaacggccagcaccgtatctccgaggtgagc
agtgctgactcagaccaaagcgtgccgagtcaccggagattctcgaaggcatccccgaga
cagaaaggtaattgttcccctgtttttggtggcatggactgcacctccccactgggggga
gacagagagcacatcaggctgctggacctctcagggaatgagttggacagcttgtcttgc
ctgatgggggacagtgtgaccttgcagcacctggaacacgtcgtccgcctggagctaagc
cagaacaaccttgtggagttccctgaacttctgtgtcagagtctgaggaatttgacccgt
ttggatctccatggtaaccatctcaagtctttcccggccggcttgctaggcttgccctca
ctgagcgtgctcaatgtgtcccggaactgtgtgggaccgcagctctgccttccgcccgct
gtgcgatgcccctcgatgaggcacttcaacctgtccttcaaccacattgccgtgttccct
gaccttctgggccagtcgctggagatgctggaggatcttttacttgaagggaacaggctt
acggtgctgtcgggccctcttctcctgcctgagatgaggctgctggacatcagcagaaac
agcattgagcgtatctgtcaggatgccctgaccagctgcctgaagctggagactctcaat
gcttccatgaataagcttagttgtttttcgtcacttccatcaaaattaacaacactgaaa
ttagctgacaataacttcacttgtgttccagaagtaattcttcagctaccacatttacga
tccctggacatgaggaacagcagcatatctgtgctgccggggcctgtcgcctggacctcc
gttaacctgagtgagctcatcttcagtcacaaccgcatcgctcttctggacatcagtgaa
cctgtgtacaagtgggctcgactggagaagttacacctcgccggcaacatgcttactgag
attccaagtgagataggcttgctggaaaacttgacgtctctggatgtgagcaggaatgag
gggctgcgctcctttccggatgaaatgggcaaactcagcaggctgtgggacctgccactg
gacgggctcagactcaacatgaacctgaagcacatcggcaacaagaccaaagacattgtc
aggttcctgcagcagcgtctcaaaaaggcagctccctacttcaggatgaagctgatcatg
gtgggaaattctcggagtgggaaaaccacactggtccagcagctcatgaagctccggagg
tcccagtggtttgcggaccagctgagcgaggccattgatgtcaaagactggtccatccgt
gtccgcgacaagagaaacatagtactgaatgtgtgggacttttcaggaggagagaaattc
agcagctcacagtgtcatttcatgagccagcgagcgatgtacatcgtggtgttcaacctg
agcaagggcccggctgaagtggaagccctgaagccctggcttttcaacatcaaggccatc
gcccccctatccccagtgatcctggtgggcactcatgccgacgtctgcgaggaccatcag
ctgcaggcatgtttggcaaaaatcaagggagagctgctgcttcaccagggcttccccgca
atcagggattatcacatggtcaacgcgtgcgaggactccgacccaatgagccgactgcgc
aaggctgtcataagggaggccactggtttcaagatccagggtcagccggtgattgggcag
cttatcccagacagctacctggagctagagaggagacttctgcaggaaagggcaagaaca
gcccacgacttccctgtgctacgtcaccagcacttgctggacattgtgcaggagaaccag
ctgcagctggatgagagcgagctggcccacgcggtccactttctcagcgaggctggtgtg
ctgctgcactttgttgacccagccctccagcttgccgatctctacttcattaaaccccag
tggctctgcagcatcgtttcccagacgtcgccgctgaaatgtgcctgtcgctcggaacag
ccgaagggcatcgtgcggcactcggtggctgagaagttcctccttgagagccggtgtttt
ccaaaacgttacttggcccagtacctgaagcttctggagaagttccagatcgctctgccc
ttcggagaagatcagctgctcataccaagcagcctgccacatcgcagaccaatgatagag
ctcccccactgtgagaactctgaagttgttgtccgactgtatgagatgccatacttccca
atggacttctggtccaggcatatcaatcgtctgctggaggtctcttcatccttgttgaat
gcaaaagaaaaagctctaagaccgaacctagtctgctggaggacaggaatccacctgaac
tggtctcctgaagcttactgtctggtggagtccacatcctgggagaatgctcctcagagc
tttgtcaagatcacggttccttgctgtcgcaaaggtcatattctacttggtcaggtcgtt
gatcacatcgactcccttctggaagagtggtttcctggcctcctcaccactgatatccat
ggcagtggggagatgttgctgaagaaatgggtgctgtatagttttgaagatggtcaggaa
tggagtaagatgcttctggaggaccttctcacacagatcaaggaaggttatctactgacg
aatccatctgacccccgatctacagttcccatttcccaaatagcaccagatctgattctt
agggatttgccagcaagtatgatgctcaacactgaagagctggagatagacctttctaat
gagtatttactgggggatggaggttttgggtccgtctatcgagctgtctacaagaacgaa
gaagtcgctgttaaaattttcaacaaacatgcctcggcgatgcacattctcaggcagctc
agacaggagctagctgtgctcgggcgcctgcaccatcccagcctggtgtctctcctggct
gctgggacgtctccccccttgctggtcatggagctggccccttgcgggtccctggactcg
ctatttcaacatgaaaatggcaacttgaaccgcaagctgcagcataggattgccctgcaa
gtggcggatggacttagattccttcatgcttccatgatcatttaccgagacctgaagcca
cacaacattcttttgtttaatctgaagacggactctgagatcatcgccaagatcaccgat
tacggcatagctcagtactgctgcagtatgggggttagaacttcagaagggacccctgga
tttcgagctccggaagttgcccgaggcaacgtcatatacaaccaacaggcagatgtgttc
tcttttggcctgttgatgtacgacctgctcacttgcggggaaaggatgtttgatggcatg
aagttccccagtgagtttgatgaagttgcagtccagggaaagctgccagatccagtcaag
cactatggctgcagcccgtggcctttgtttgaagatctgatgaagcactgtatgaaggag
aaccctcaggaaagaccctcagcatcagaggtgtttgacaagctcaactcgggcgagatg
ctctgcctgatgcgacgggtggatgtttgccgggtgccgaacgctgagtgctttgcagtg
gcccgtgggggtgacgcggggctgtgtgtcagtgtcggaggaggcagcagcagccagaga
agaggctgtatcacatctgtcgtgctgagctctgggaaactgactgcccaggagattgat
agcagtcccgtcctgtgccttgtgacagtgcgagtcccagaggaaagcagcgattggctg
gtggcaggaacacaggcaggatctcttatagtaataaacacggcggacatgtctgttcta
cacggtcttcagagagtcaccgatgctgtgacttccctcttctttcactgtgacccagaa
cacaggcataagaggagccatttgttagtgggaactgctgatggagttctggctgtttat
gatgaatcggagattcagtatgataatggccagcctctgaagacactgcatatcgggacc
attaacactcccatactgagcctgggccaatctgcttgcccactggacggaaccaccatc
tgggccggctgtggaacccaagttttgggatttaatgcagactatgatatcctgaagacc
attgaaaccaaactgaattgctttaatcagtggggcagtgaaaccaatatttcccgcttg
gcggtggataagcacatctatgtcagcaaggtgaggacccacacagttgaagtttgggac
aggaagagcgagaggatgagcaacctcattgactgtgctcagatactaagacagagattg
agggtttcatatgcagagagggaactggacactgggatttcctgggccagtgtgaaagcc
ctgctgatacagcacaacacatctctctggattggtaccaggggtggtcatgtgatcctc
atggacctgttgacctgcctgcccctgcaggtcatcggccatctctgccagtctgtaagg
agcatgatgttggtccattcagaagcactaaacccaaggaatgttgttctcgtcctggga
cgaagcagcagggcgagaagggagaaggccagaatggactacgaagatgactccacccta
ctggtctggaacagcacacagccccaggaggtccgagatctgaagaaacactgtgacatg
aggatggagatcgctgacaagatgaggacaccacgaaacacctga
DBGET
integrated database retrieval system
