Peromyscus leucopus (white-footed mouse): 114690416
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Entry
114690416 CDS
T07241
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu04140
Autophagy - animal
pleu04141
Protein processing in endoplasmic reticulum
pleu04210
Apoptosis
pleu04932
Non-alcoholic fatty liver disease
pleu05010
Alzheimer disease
pleu05012
Parkinson disease
pleu05014
Amyotrophic lateral sclerosis
pleu05016
Huntington disease
pleu05017
Spinocerebellar ataxia
pleu05022
Pathways of neurodegeneration - multiple diseases
pleu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
114690416 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
114690416 (Ern1)
09143 Cell growth and death
04210 Apoptosis
114690416 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
114690416 (Ern1)
05012 Parkinson disease
114690416 (Ern1)
05014 Amyotrophic lateral sclerosis
114690416 (Ern1)
05016 Huntington disease
114690416 (Ern1)
05017 Spinocerebellar ataxia
114690416 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
114690416 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114690416 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
114690416 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pleu01001
]
114690416 (Ern1)
Enzymes [BR:
pleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
114690416 (Ern1)
Protein kinases [BR:
pleu01001
]
Serine/threonine kinases: Other
IRE family
114690416 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
114690416
NCBI-ProteinID:
XP_028721026
LinkDB
All DBs
Position
8b:85923257..86026218
Genome browser
AA seq
977 aa
AA seq
DB search
MPARWLLLLLALLLPPPGPGSFGSASTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSTFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTV
SQDVEEKLVHAPTKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQ
FQKELEKIQLLQQQQMPFHPHGDLTQDPEFLDSSGLFSESSGTSSSSPSPRASNHSLHSS
SSASKTGTNPSLEQDEEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAV
GRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQ
RQANILLGACSLDCFHSDRHEDVIARELIEKMISMDPQQRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKESLDGPIVRQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPYLLSHTYRAMELCRHERLFQTY
YLHEPTEPQPPVTPDAL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggtggctgttgctcctgctggcgctgctgctaccgccgcccggccccggg
agttttggaagtgccagcacagtaaccctgcccgaaaccctgttgttcgtttccaccctg
gatggaagtttgcatgctgtcagcaagaggacaggctcgatcaagtggactttaaaagaa
gatccagtcctgcaggtcccaacacacgtggaagagcctgctttcctcccagatcccaat
gatggcagtctgtacacacttggaggcaagaacaacgaaggcctgacgaaacttcccttt
accatcccagaattggttcaggcatccccatgccgaagttcagatggaatcctctacatg
ggtaaaaagcaggacatttggtatgtcatcgacctcctgactggagagaagcagcagact
ttgtcatcaacctttgcagacagtctctgcccatcaacctccctgctgtatcttggacgg
acagaatacaccatcaccatgtatgacaccaagacccgagagctccgttggaatgccacc
tattttgactatgcagcctcactgcccgaggatgacgtggactacaagatgtcccacttt
gtgtccaatggcgatggactggtggtgactgtggacagtgaatctggggatgtcttgtgg
atccaaaactacgcctctcccgtggtagccttttacgtctggcagcgggagggcctgaga
aaggtgatgcacatcaacgtcgctgtggagactctgcgctacctgaccttcatgtccggg
gaagtggggcgcatcaccaagtggaagtatccgttccccaaggagacagaggccaagagc
aagctgacgcctaccctgtatgttgggaagtactccaccagcctctatgcctctccctca
atggtgcacgagggggttgctgtagtgccccgaggcagcactcttcctttgctggaaggc
ccccagacagatggcgtcaccattggagacaaaggagagtgtgtgatcacccccagcaca
gacctcaagtttgaccccggactcaaagggaagagcaagctgaactacttgaggaattac
tggcttctcataggacaccatgaaactcctctgtctgcatctaccaagatgctggagaga
ttccccaacaacctgcccaaacatcgggaaaatgtgattcctgctgattcggaaaaaagg
agctttgaggaagttatcaacctggttggccagacttcagaaaatacaccaaccaccgtg
tctcaggatgtggaagagaagctggttcatgcccccaccaagcctgaggcccccgtggac
tccatgctcaaggacatggctactattatcctgagcaccttcctgctggttggatgggtg
gccttcatcatcacttaccccctgagcatgcatcagcagcgccagctccagcaccaacag
ttccagaaggaactggagaaaatccagctcctgcagcagcagcagatgccattccaccca
catggagaccttactcaggaccctgaattcctggattcatctggcctcttctcagagagc
tcgggcaccagcagctccagcccgtctcccagagcctccaaccactcacttcactccagc
agctctgcctccaagactggcaccaacccctccctggagcaggatgaggaggatgaggaa
accagaatggtgattgttgggaagatttcattctgccccaaggatgtcctgggccatgga
gctgagggcacaattgtatacaaaggcatgtttgacaaccgtgatgtggccgtgaagagg
atcctccctgagtgttttagctttgcagaccgtgaagtccaactgcttcgagagtcagat
gagcatccgaacgtgatccgctacttttgcacagagaaggaccggcagttccagtacatt
gccattgaattgtgtgcagccaccctacaagagtatgtggagcagaaggactttgcccac
cttggcctagagcccatcaccttgcttcagcagaccacctcaggcctggcacacctgcac
tctctcaacatagttcacagagacctgaaaccccacaacattctcctctccatgcccaat
gcacatggcagaatcaaggccatgatctctgactttggcctctgtaagaagctggcagtg
ggcaggcacagtttcagccgccgttcaggggtacctggcactgaaggctggatcgccccg
gagatgttgagtgaggactgcaaggagaatcctacctacacagtggacatcttctccgca
ggctgtgttttttattatgtcatctctgagggcaaccatccctttggcaagtccttgcag
cggcaagccaacatcctcctgggcgcctgcagccttgactgcttccactcagacaggcat
gaggatgtcattgcccgtgagttgatagagaaaatgatttcgatggacccccagcagcgg
ccttctgcaaagcacgtgctaaaacacccattcttctggagcctggaaaagcagctccag
ttctttcaggatgtgagtgaccgaatagaaaaggagtccttggatggcccgatagtgagg
cagctggagagaggcgggagagctgtggtgaagacggactggcgggagaacatcactgtc
cccctgcagacagacctgcgaaaattcagaacctacaaaggtggctctgtcagagatctc
ctccgagccatgagaaataagaaacaccactaccgagagctgcccgtggaggttcaggag
acactgggctccatcccggatgactttgtgcgctatttcacatcgcgcttcccctacctc
ctctcacacacctaccgagccatggagctgtgcagacatgagagactcttccagacctac
tacttgcatgagcccacagaaccccagcctccagtgactccagatgccctctga
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