Peromyscus leucopus (white-footed mouse): 114695048
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Entry
114695048 CDS
T07241
Symbol
Pde3a
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00230
Purine metabolism
pleu01100
Metabolic pathways
pleu04022
cGMP-PKG signaling pathway
pleu04024
cAMP signaling pathway
pleu04924
Renin secretion
pleu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114695048 (Pde3a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
114695048 (Pde3a)
04022 cGMP-PKG signaling pathway
114695048 (Pde3a)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
114695048 (Pde3a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
114695048 (Pde3a)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
114695048 (Pde3a)
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GFIT
Motif
Pfam:
PDEase_I
TgpA_N
Motif
Other DBs
NCBI-GeneID:
114695048
NCBI-ProteinID:
XP_028728065
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Position
3:complement(131919802..132207096)
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AA seq
1158 aa
AA seq
DB search
MAVPGEAAQDLAKPGLGRASPAQVTSWDHHGRGASRPSPRSLGCRGCWGVQALQPLRRSP
QLSSALCAGSLSVLLALLVRLVGGEVGGKLESSQEAAAEEEEEEGARGGVFPGPRGGAPG
GGAPLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAIALLAACCAGEALVQLSLGVG
DGRLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVALTSALRTVALVSLERFKVAWRPYLA
YLAAVLGLLLARYAEQILPQCFGPAPPRERFRSQLSARTKEEIPGWKRRRRSSSVVAGEM
SGCSGKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSGTSITVDIAVMGEAHGLITDLL
ADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFGENYTCSDSEEGLEKDKLAI
PKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSALNPDS
WNAPVSTTLTKSRSFTSSYAISAANHVKAKKQNRPGGLAKISPVPSPSSSPPQGSPASSP
VGNITSAQFPESSEITAKRGPGSHRALTYTQSAPDLSPQILPPPVICSSCGRPYSQGNPP
DGPSERSGSAIQKPNKTDDTSQVTSDYETNNNSDSSDILQNEEEAECQREPLRKASACGT
YTSQTMIFLDKPILAPEPLIMDNLDSIMDQLNTWNFPIFDLVENIGRKCGRILSQVSYRL
FEDMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSV
ISDHGSASDSDSDSGFTHGHMGYVFSKMYHVPDDKYGCLSGNIPALELMALYVAAAMHDY
DHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLGNLDHVEFKHFR
FLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCK
ELHLKWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDS
AGLMPGRWVDDSDDSGDTDDPEEEEEEAETPNEEEICENNTAPSISPGANSRPMDKTKRK
KTFKRRKIYCQITQHLLQNHTMWKKVIEEEQCSEGIENQSLDQAPLQHSSEQIQAIKEEE
EEKGKPRAEETLAPQPDL
NT seq
3477 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgccgggtgaggccgcccaagacctggccaagccaggcctcggaagggcgagt
cccgcccaggtgaccagctgggaccaccacggtcgtggcgcgtcccgtccatccccgcgg
agcttgggctgccgaggttgttggggagtccaggcgctgcagccgctacggcgctcgccg
caactctcctcggcgttgtgcgcgggctccctgtccgtgctgctggcgctgctggtgagg
ctggtcggcggagaagtcggaggcaagctggagtcgagtcaggaggcggcggccgaggag
gaggaggaggaaggagcccgagggggcgtcttcccgggccctcggggaggtgctcccggg
ggcggcgcgccgctcagcccttggctgcagccggccgcgctgctcttcagtctcctgtgc
gccttcttctggatgggcttgtgcctgctgcgcgccggggtgcgcctgcctctggccatc
gcgctgttggccgcctgctgcgcgggggaagcgctggtgcagctctcgctgggcgtgggg
gacggtcgcctgctgtcgctgcccgccgcgggggtcctgctcagctgcctgggtggcgcg
acatggctggtgctgaggctgaggctgggcgtcctcatggtcgccttgactagcgcgctc
aggacggtggccctggtttccctggagaggttcaaggtcgcctggagaccttacctggcg
tacttggcggccgtgttggggctgctgctggccaggtacgccgagcagatcctgccgcag
tgcttcgggccggctccgcccagggagcggtttaggtcccagctgagcgcgaggaccaag
gaagagattccggggtggaagaggaggaggcggtccagctccgtggtggccggcgagatg
tctggctgcagcggcaagtcgcaccggaggacctccctgccctgcatacccagggagcag
cttatgggtcattcagaatgggaccacaaaagaggaccacgaggatcccagtcaggaacc
agcatcactgtggatatcgccgtgatgggcgaggcccatggcctcattactgacctcctc
gcggacccttctctgcccccaaacgtgtgtacatccctgagggccgtgagcaacttgctc
agcacccagctcaccttccaggccatccacaagcccagagtgaaccccactgtaaccttc
ggtgagaactatacctgctctgattctgaggagggcttggagaaagacaaactggccatt
cccaagcgcctgagaaggagtctgcccccaggcttgctgagaagagtctcgtcgacttgg
acaaccaccacctctgccacaggtctgcccaccttggagcctgcaccggtgcggagagac
cgcagtgccagcataaagcctcacgaagcaccttcacccagtgctctcaatcccgactct
tggaatgccccagtgtcgacgactctcaccaagagcaggtccttcacttcatcctatgcc
atctctgcagctaaccatgtaaaagctaaaaagcaaaacaggccaggtggccttgctaaa
atttcacctgtaccctctccctcctcctcacctcctcaaggatcgcctgccagtagtccc
gttggcaacattacttcagcacagtttccagaatcctctgaaataactgccaagcgaggc
cctggatctcacagggccttaacttacacccaaagtgcccctgacctgtcccctcagatc
ctgcctccacctgtcatatgtagtagctgtggcagaccttattcacaggggaatcctcct
gatggaccttcggagagaagtggctcagccattcagaaaccaaacaaaacagatgacact
tcccaagttacctccgattatgagaccaacaacaacagtgacagcagtgacattttgcag
aatgaagaggaggccgagtgccagagagagccactgaggaaagcatcggcttgtggcacc
tatacttcccagaccatgatcttcctggacaaaccaattcttgcccctgaacccctcatc
atggataacctggactcaattatggaccagttaaacacctggaattttccaatttttgat
ttagtggaaaatataggaagaaaatgtggtcgtattctgagccaggtatcatacagactg
tttgaagacatgggcctctttgaagcctttaaaatcccggttagggaatttatgaattac
tttcatgctttggagatcggatatagggacattccttatcataacagaatccacgccact
gatgttttacatgctgtgtggtacctcacaacgcagccaattcctggcctcccaagcgtg
attagtgatcatggatcagcaagcgactctgattctgacagtggatttacacacggacac
atgggatatgtgttttcaaaaatgtatcatgtgccagatgacaaatacggatgtctgtct
gggaatatcccggccttagagttgatggctttgtatgtggctgcagccatgcatgactac
gatcacccagggaggacgaatgctttcctggtggccaccagtgcccctcaggcggtgctg
tacaatgaccggtctgttctggagaatcatcatgccgctgcagcatggaatctctttatg
tcccggccagagtataacttcttaggtaatctagaccacgtggaatttaagcatttccgg
ttcctagtcattgaagcaatcttggctactgacctgaagaaacactttgactttgtagcc
aaatttaatgccaaggtaaacgatgatgttgggatagattggaccaatgaaaatgatcgt
ctcttggtgtgtcaaatgtgtataaagttggctgacattaacgggcctgctaaatgtaaa
gaactccacctgaagtggacagagggcatcgccagtgagttttatgagcagggcgatgaa
gaagccagcctcggtttgcccataagcccctttatggaccgttctgccccacagctggcc
aatcttcaagaatcctttatttcacacattgtgggtcctctatgccactcctatgactct
gcaggtctcatgccaggaagatgggttgatgacagtgatgattcgggagacactgatgac
ccagaagaagaggaggaagaagctgaaacaccaaatgaggaagaaatctgtgaaaataat
acagctcccagcattagtcctggtgctaacagtagacctatggacaaaacaaagagaaag
aaaactttcaaaaggaggaaaatctactgccaaataactcagcacctccttcagaaccac
acgatgtggaagaaagtgattgaagaggaacagtgctcagaaggcatagagaaccagtct
ctggaccaggctcctctacagcattcctcagagcagatccaggctatcaaagaggaagag
gaggagaaggggaagccaagagcagaggagaccctggctccacagccagacctgtga
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