Parus major (Great Tit): 107201729 Help Entry 107201729         CDS       T04864                                  Symbol MDN1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism pmaj  Parus major (Great Tit) Pathway pmaj03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:pmaj00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     107201729 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:pmaj03009]     107201729 (MDN1) Ribosome biogenesis [BR:pmaj03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     107201729 (MDN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_16 AAA_3 AAA_7 AAA_22 nSTAND3 TsaE AAA_18 Sigma54_activ_2 AAA_14 ABC_tran AAA_6 MDN1_4th bpMoxR Dynein_heavy DUF815 PduV-EutP Motif Other DBs NCBI-GeneID:  107201729 NCBI-ProteinID:  XP_015476914 Ensembl:  ENSPMJG00000001617 LinkDB All DBs Position 3:77043866..77135866 Genome browser AA seq 5569 aa AA seqDB search MAAELRFRLAEPLQLVARRNEKSGVELSRFLAKQVWTQQDRQCILNTLAQLLLDKECTVL VGRQFRPILLDLLERNAEAIKAGGQINHDRHERLCVAMSKLVADHPDVLPFALRYFKTTS PVFQRLFLESSDASTVRYGRRRMKLRDLMEAAYRFLQKEPSVFRELWDWSVCIPLLRSHD TLVRWYTSNCLALVTCMNDEHKLSFLKKIFNPEELIHFRLKLLEESQLQNVERALVLANP DSTFWQKEKELRYTQGHVVSGDLSAHVVAVCGIVLPRLQHVAEEQENNTSNFVLVESAFT NLQNLAIAVAYQTPVLLEGPIGCGKTSLIEYLAAVTGRAKPPHILKVQLGDQTDSKTLLG MYRCTDVPGEFVWQPGTLTQAVTKGHWILLEDIDFAPLDVISVLIPLLEKRELLIPGRGD CLKVAPGFQVFATRRIFSCGGGWYRQQSSHAALLDKYWTKIHLDNMSKGELKEVLQKRYP SLALVTDHLLDIFIDLAGDKYQAPENSAAGSSHVPEAASESRSEHKKPNLEGRELSLRDL LNWCSRIAYNFDSNSSTTAVNIFQEALDCFTAMLSNQGSRQKMAKVIGSYLNISKKKVEF FCELYKPEISIREQEVSIGRVNLVKKQNHALTVQRAKHTFAATRPSAVLIEELAVCVVKG EPVLLVGETGTGKTSTVQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVDNKLIWLPLRE SFEELFSQTFSRKKNQTFLGHIQTCYRQKRWHDLLKLMQHIHKSAINKEVKENASGLPLK EKWEAFGLKLTHAHQQMKMTENALLFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLS GLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPLGIRNRFTELYVEEL RNEGDLHILVMDYVRSLNVNKNTVQGIVNFYLSVRKEAETKLVDGTGHRPHYSLRTLCRA LRFAASNPCGSIARSLYEGFCLSFLTQLDRGSHPVVQKLICQHIVSGNIKSLLKQQIPKP QGGSFILIEGYWISAGDKEPTVDESYVLTPSVKLNLKDIVRVVSAGTHPVLIQGETSVGK TSLIRWLAAATGNHCVRINNHEHTDIQEYIGCYTSDASGKLVFKEGILIDAMRKGYWIVL DELNLAPTDVLEALNRLLDDNRELFITETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRA FRNRFVELHFDELPSAELETILHKRCSLPPSYCSKLVKVMLDLQSYRRGSTVFAGKHGFI TLRDLFRWAERYRLAEQLQKEYDWLQHLANDGFMLLAGRVRKQEEVDVIQNVIEKHFNKK IYPESLFSGESVKKLLAKSSTWMSVMDRDFNHVVWTQGMRRLAILVGRALEFGEPVLLVG DTGCGKTTICQIFAALANQKLYSVNCHLHMETSDFLGGLRPLRQRSKDQEESDGSRLFEW CDGPLVLAMKEEGFFLLDEISLADDSVLERLNSVLEAEKTLVLAEKGGQDDEENEVELLV AGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSNGRDDLVQIVKHNLHPGLSLGA VNHEGADIAELMMDFVEWFTNQEFGRQCILSVRDVLAWINFMNVMAEDDSSSAKGCSRLN ISPVMSFIHAACLVYIDGIGSGTTSCSADTALLAREKCLTFLHEKMSQFFELTDYQKSEL KIYDRTKEKELVWMDNFMGIHPFFIPRGPILQRSNMTDYALNAGTTAVNAQRLLRALQLN KPILLEGSPGVGKTSLVAALAKASGNCLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWR DGPLLAALKAGHWIVLDELNLASQSVLEGLNACFDHRAEIYVPELGMNFHVQHKTTKIFG CQNPYRQGGGRKGLPKSFLNRFTQVYVDPLSAEDMEFIGNTLFPAIDKTIIAKMVAFNNK IEKEVMAEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGWYDPGQHVFLVYGERMRTRED KEKVISVYRDIFGQEANVYTGTREFHINPYNVQIGYSVLSRGSYIPHSGRTLSLLHHSLQ SLESIMKCVHMSWMVILVGPAAVGKTSLVELLAHLTGHQLKIMAMNSAMDTTELLGGFEQ VDINRPWQRLLEKVEHAVSTLVRDGLLLAELCADDAELLLRAWSNFILNYKPKSLGEGGG RVTAELVSKLEGILVLTQRLNNKINSYTKAEFAHLVEEFRHFKLQQAQAADCKSHGTFEW VDGMLVQALQSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTMSERGVIDGTIPTIAPHP NFRLFLSMDPVHGEISRAMRNRGIEIYIPGENDGNMLDSLDLKLLLHGLGLVGDSVCDAL LAVHSETKAAIAGSVSSLSPLLQAAVLIVQQIQRGFGLAKSFYRACWEVYGRSQQLQINQ KLVLELVTRHASSLASPDTWGESLLAVGLWPDSLPSGLFAAEDSLLSTVQSDGQVLMYCL HRLNLRNCRTLPVTLQDLKKVMQSTNPESLKFSAVEIDPNWMDKMEVLQASVKFFIAKAT NQDWKLRVKWLNSLAKNLPQVLDSVRIQLEASAVALGCFYASPLSSGVSNMIKLLQPTMT DEHVMPLDPRWNMQFLEIIRNSVNFDTEMEHADQLLMLLKSAANRAVLFLDREKRSYIEK SLIASKKPRNSVLGMSLEFHKNPGSYSSLPHGIVVNLAAFFELWDAFVLHWVKNTQVALS DDDMHDVLYCWLWRDRFWAVSDTVTADSPGLSLLALHWHWVMKHLIDRIPQMLIGSDQNK ISREIQSVSQQIQNCLVNPAGISANMKILQKSLGRPLPFKDKLGMECFSQLKALSKPLNI LELRSACGESRWQEKMCCVKIAATGVKMKKALLQADGLIIRANHLEDVSLGELQIFLEAV HSQLKAEGVTYSYSEERLPEDIISKQLDPALLNHLCSQVQMWPAMEYIGVLWQYKLTADY VAKACARRKNCSQELSVCSDLAQFIAFSLQLTPAASHQLSGLWHLLHLNEISPEEMSLLS SQLVNAVLASFWSSTFTMDPDYWLTWRPLPATEENNFSKSHVNRSMKGPGILTRAVFSKC FFEILTSSSKTSQWDVSGLPVLSSSHVTLGEWMERAQQLHKVSTALWTNLAVSSMADFRQ TDARLQGVMLSRQLSALVHLIPVALQEEFLECCEKLYLKDAVAYEYLLKILESITDQELL PKEFLFLLITCLHQFYGEGLQELPETAWRGSLWVSLGLVQIQMWLPQTRFDPAVKREYKL KYSKEELYQLECEWKTHDFSSELHTGKSIEDETVSNYIHPHIRLLHERMQRLKEQISSLS RRKAFRPPAPLYDCLYQEAHQYINSIAQISSVQDLLARLLQFLRGERPKSLQAIQNLLSE EASWQQSHHQFRKHLAEEYAVFPDAIIPLQAAILQLQHGMRLVASEAYAVLQSSVCPADL TNLLTSLLAFPSVGRAFPTYFSRAEVLCSVNSVGVLNGLKKFSLKHSEGGSEGGEQPSPT LEQLLVNALLHLRCHVLSRGEMDQKSLQLFRHLFRAIVNEWDEQERRAQEQEAMERSLYR YRSKSHGKGRSEEEEEEEEFKRRFPFHEKDFEDITAQPSLEEKMETEDPVEDQLEVDRAL LSKSSMQTVMKVHQQLCLNFARSLWYQQSMASHQAKHYFSTFISCYQTGACLVSQFYPLM GAEMNDSLLGSQLLLSTLLHNTFFEEVTSDLVLQQDGPYDFYQHPNIQQVRQCQPVLDNF AKEINGLLQEWPEHPVLVQLLVVMDRIRSFPLSSPLSKFLNGLEILLAKAQDWEENACRA LSLRKHLDLVTQLIIQWRRLELNCWSVSLDNIMKQHVDKSTKYWFSIYQMIEKYVQEQTE ANTEGAEQMDLKTLVSTLQAFIEGSTLGEFHARLQVLLVFHCHVLLMPQVAEKDVLCSIL WNLYNYYKQFSECVEAKIADLRQPIEKELKEFVKISRWNDVSFWAIKQSVEKIRRTLFKF MKKFEVVLNEPCQPALVEIGKEEQLDCMQKQEESDDKETKIQRLNNTLRKVLSARTDVTK RALPECQGVITFHTESLQYRLSKLTKKMKKMCSAVTENNSLLNLVENLDQFTGGIIVSVA ELQNLTFDQTATKEKQKSEAKHIQMQKQRALSDLFKSLAKTGLSYRKGLSWSRSKDCQEV LYLRPLDLCSALAAVNCTHELDATLLTEISCAWDGCQKYFYRSLARHSRLQTALLAPAKD IGLGSIERCKGFTAHLMQMLVRQRRSLTALTEQWILLRNLLSCIQEIDSRLTADREYSAA FPPQDSIQRWTDRLQQLCMQCVMVLEELSWFIQCCPKEESARPNDSERTDVKDSIPQSSV PEMGNVLARIPDLIPSDLKHLSPVTIEQLPPGCRMRNKDQLWVQVSTQLTAMTADVKAVK AEVDRVRQQSRETSFHSWRDFEVCTSAVSCLLEVSAQLQSIESLFLPNGQDSEAANQMAL IKSLKYIQEVISNTSSDFTVWRTQLLASVSDCTGNQQSDEEFVEQFSTKVEAVIRAVLYA VQCLVERKQEGGKEEEKSSEENEDAALLDVIKAGHITKLLYEDLSADLESLHVQKAILGV SELLEILKSYREDCTSYKHKFFNQSCYLLVRLKPMLCKYSDLILFYLTVSLASHRSTGKL LSVLTSIFTELALKGFCLPKELLEDEAGEGATEFHDYEDGGIGEGEGKKDVSDKIESEDQ IEDSFRKGEEKEKEDQDSKPDIEGEDNAIEMSEDFEGKMHDGEMEKKEDEENSDEEEELD KQMGNLDNAEADDKLDERLWGDEDDDDDDEDTSSKTEETGPGMDEEDSELVAKDDNLGTG NKDNKKQPPKNKEKEQEEEDCGNTEKIHEQIDEREYDENEVDPYHGQQEKEPEVEPLDLP DDLNLESNEKSDDEDEEEENDFERDEKPVDFNEAEKTEEQNEENTGETEKDEQDAKAAEE GISEDKEEKEDEGDKDAHDQEEKPGNTEDAEEEEEESQPPDDKKNESAEDKGIPNEDQGL QPQEEEDKDNSETDEQIPEAEERMEHETQGQTGQENLQSDSAVELAGEASEKDESREESG TGASSANQSEGHESTCMARMASEKQSRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTM ESSSEAKQDTTQPKQSVEEADAFEHIKQGSEHYDAQTYDVASKEQEKPIIPPEEKEEGDC EDVAMETEMQDEDLRAVDTEELKPEKKKSTATKPPGPGDVEPELQTFDSEDVNESAPEKL LKVTEEKPERSKDSTIHTAHQFLMDIPQHIIRDPEELRKELERQLEAWQTQQPGTPEEEK EAAQLWQKYLVLTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLNMRKVIPYIASQFR KDKIWLRRTKPSKRQYQICLAIDDSSSMIDNHSKQLAYESLAVIGNALTLLEVGQIAVCS FGETVQLLHPFHEQFSDQSGTRILRLCKFQQKKTKIAQFLESSANMFAAAQQLSQNINPE TAQLLLIVSDGRGLFLEGKERVTAAVQAARNANIFVIFVVLDNPNSRDSILDIKVPIFKG PGELPEIRSYMEEFPFPFYMILRDVNALPETLSDALRQWFELVTASDTL NT seq 16710 nt NT seq  +upstreamnt  +downstreamnt atggcggcggagctgcggttccgcctggccgagccgctgcagctggtggcgcgcaggaac gagaagagcggtgtggagctgagcagattcctggcgaagcaggtttggactcagcaggat cgtcagtgcatcctcaatactttagcacagttattgctggataaagaatgtactgtattg gttggccgtcaatttcggcccatcctgctggatttgttggaaagaaatgcagaagctatt aaagctggtggccaaatcaaccatgatcggcacgaaaggctgtgtgtagcaatgagcaag ctggttgctgaccatcctgatgttttgccatttgctttaagatactttaaaactacatca ccagttttccagaggcttttcctggagagctcagatgcaagcacagtccgatacgggcgc agacgaatgaagttacgggacctcatggaggctgcctacagatttttacaaaaggagcca tcagttttccgggagctgtgggactggagtgtgtgtattccactcctaaggagtcatgac actttagtccgttggtacacttcaaactgtcttgctctggttacatgcatgaatgatgag cataaattatctttcctgaagaagatattcaatcctgaggagctgatacatttcagactg aagttgctagaagaatctcagctgcagaatgtggaacgagccttagttttggctaatcca gactccacattttggcaaaaggagaaggaactgcgctatacacaaggacatgttgtgtcg ggcgacctctctgcacatgtagtagctgtctgtggcattgtgctgcctagactacagcat gttgctgaagagcaggaaaataacaccagcaattttgttttggttgaatctgccttcaca aatcttcaaaaccttgctattgctgtagcatatcagactcctgttttattagaaggacca ataggatgtggaaaaacgtctttaattgaatatttagcggctgttacaggaagagcaaaa cctcctcatattttgaaagttcagcttggagatcaaactgatagcaagacgctgctgggg atgtaccggtgcacagatgtaccaggggagtttgtgtggcagcctggcaccttgacacaa gctgttaccaaaggtcactggatacttctggaggacatcgattttgctcctctggatgtg atctctgtgctgattccacttttggagaaaagagagttactgattcctggtcgtggtgac tgtttaaaagtagcaccaggattccaagtttttgcaaccaggaggatattcagctgtggt ggaggttggtacaggcagcaaagcagccacgctgctctcctggacaaatactggaccaag atacatctggataacatgagcaaaggagagctcaaggaggtcctgcaaaagaggtacccc agccttgctcttgtgacagatcacttgctggatattttcattgaccttgcaggagacaag tatcaggcaccagaaaacagtgctgctggctccagtcatgtgccagaagcagcatcagaa tcaagatcagaacataagaaaccaaatctggaaggacgagagctatctctaagagaccta ctgaattggtgcagcagaattgcttacaactttgacagtaattcttcaaccacagcagtg aatatttttcaggaggcattggactgtttcacagccatgttgtccaaccaagggagcaga cagaaaatggcaaaagttattggaagttacctaaacatttcaaaaaaaaaggtggagttc ttctgtgagctctataaaccagaaatttcaatacgggaacaagaagtctccattggaaga gtgaatcttgtgaagaagcagaatcatgctctcactgtacaaagggcaaagcataccttt gctgccacacgaccatctgcagtactgattgaagagcttgcagtgtgtgttgtcaaagga gagcctgtgcttttggttggtgaaacaggaactggaaaaacctcaacggttcagtaccta gctcatattacaggacaccgtttgagggttgtcaacatgaaccaacaaagtgacacggca gatctcctagggggttacaagcctgtggataacaagctgatctggctccctctgcgagag tcttttgaagaactcttctctcagacgttctccaggaagaaaaatcaaacattcttggga cacattcagacttgctacaggcagaaacgttggcatgatctgctaaaacttatgcaacat attcataaatctgctattaataaagaagtaaaagaaaatgcatctggcttaccactgaag gaaaagtgggaggcatttggtcttaaactgactcatgctcatcaacagatgaaaatgaca gaaaatgctcttctctttgcatttgttgagggtactctggcacaggcagtaaaaaaagga gagtggattttattggatgaaattaatttggctgcagcagagactttggagtgcctgagt ggtttattggaaggatcatctgggtcactggtgttactagacagaggagatacagagcct cttgtccgtcatcctgattttcgcttgtttgcatgcatgaatccagctacagatgttgga aagagaaatcttcctctaggaataagaaacaggtttactgaactttatgtagaagaattg agaaatgaaggagacttgcatattcttgtaatggattatgtgagaagcttgaatgtgaac aaaaatacagtgcaaggaattgtgaacttttatttatctgtgagaaaggaagcagaaaca aagttggtggatggaactggccaccgacctcactacagtctccgtaccctatgcagggca ttgagatttgcagcatctaatccgtgtggcagcatagcacgctccctgtatgagggcttc tgtttgagtttcctgacacagcttgacagaggttctcacccagtggttcaaaagctaatt tgccagcatatagtctctggcaacatcaaaagccttctcaagcagcaaataccaaaacct caaggagggagttttatacttatagaaggatactggatttcagctggggacaaagaacct acagtagatgagagttatgtgctcaccccttcagttaagcttaatctgaaagacattgtc agggttgtgtccgcagggactcatccagtactgattcaaggagagacctctgttggtaaa accagtttaattcgctggttggctgctgctactgggaatcattgtgtaaggattaacaac catgagcatactgatatccaagaatatattggctgttacacatcagatgcctctggaaag ttggtatttaaggaaggcattctcatagatgcaatgagaaagggctactggatcgttcta gatgaattgaatttggctcccactgatgttctggaggctctcaaccgcttgttggatgat aacagagagctgttcattactgaaactcaggaagttgtcaaagctcaccctcgcttcatg ctgtttgccacacagaatcctccaggtctctatggtggcagaaaggttttgtccagagcc ttcagaaatcgttttgtggagttgcattttgatgaactgccaagtgctgaactggaaacc atccttcacaagcgatgcagtttgccaccttcttactgcagcaagcttgtcaaagtcatg ttagacctgcaatcttaccgcagaggttcgacggtgtttgctgggaagcatggattcatt accctgcgggatctgttccgctgggctgaaaggtacaggttggcagagcagctgcagaag gagtatgactggcttcagcacttagcaaatgatggttttatgcttctggcaggcagagtc aggaaacaggaggaggtggatgttattcaaaatgtcattgaaaaacacttcaataaaaaa atatatcctgagtctctcttctcaggggaaagtgtcaaaaagctactggctaagtcttcc acgtggatgtcagtgatggacagagattttaaccatgttgtctggactcaagggatgagg agacttgccattttggtgggacgagccctggagtttggtgaaccagtactgctggtggga gacactgggtgtggtaaaactacgatttgtcagatctttgcagcattagcaaatcagaag ctgtactcagtgaattgccacctgcacatggagacatcagacttcctgggagggctgcga ccactcaggcagaggtccaaagaccaggaggaatccgatggttctagactctttgagtgg tgtgatggacctcttgttttagcaatgaaggaagaggggttttttctccttgatgagatt tctttagctgatgattctgtactggagcgacttaacagtgttcttgaagctgaaaagaca ttggtacttgctgaaaaaggtggtcaagatgatgaggagaatgaagtagaactattagtt gcaggaaagaaattccgtatccttgcgaccatgaacccaggaggtgactttgggaaaaaa gagctttcccctgcgctgcgcaacagatttacagaaatatggtgtccacagagcaatggc cgggatgatttggtgcagattgtgaaacacaatcttcatccaggattgtctctgggtgca gtaaaccacgagggggcagacatagcagaactcatgatggactttgttgaatggtttact aatcaagagtttggtcgccagtgtattctcagtgtgagagatgtcttggcctggattaat tttatgaatgtcatggcagaggatgattcaagttctgctaagggatgcagccgccttaac atttctccagtgatgtcttttatccatgctgcatgtttggtgtatattgatggaatagga tcaggtacaacatcctgctcagctgatacagctttattagctcgtgagaaatgcctgaca ttcttacatgagaaaatgagtcaattctttgagctgactgattatcagaagagtgaacta aagatttatgacagaacaaaggaaaaagagcttgtatggatggacaactttatgggaatt cacccattttttattccaagaggccctattctccagaggagcaacatgacagattatgct ttaaatgctgggactacagcagtgaatgcacaaagattgttaagagccctacagcttaac aaacctattttgttggagggctcaccaggagtgggcaagaccagcctagttgctgccctg gcaaaagcctcaggcaactgtcttgttcgaatcaacctgtctgagcaaacggatgtgaca gacttatttgggacagacttgcctgttgaaggtggaaagggaggagaatttgcctggcgt gatggaccactgttagcagcactaaaggctggacactggattgtattagatgagttgaat ctggcttctcagtctgtgttagaggggcttaatgcgtgttttgaccacagagctgagatt tatgttccagaattgggaatgaattttcatgtacaacacaagacgactaagatttttgga tgccagaatccatacagacaaggaggtggaaggaagggtctccccaagtcctttcttaat agatttacgcaggtctatgttgatccactgtcagcagaagatatggagtttattgggaat acactgtttcctgctattgataaaactattattgctaaaatggttgctttcaataacaag attgaaaaagaagtaatggctgaaaaaaagtggggacagaaaggaggaccctgggagttc aacttaagagatcttttccgctggtgccagcttatgcttgttgaccagtcaccaggatgg tatgatccaggccagcatgtgtttttggtatatggagaaagaatgagaaccagagaagac aaagaaaaggttatttctgtatacagagacatttttggccaggaggccaatgtgtataca ggaaccagggagtttcacatcaatccatataacgttcagattggttattcagttctttct cgtggcagctatatacctcactctggcagaactctctcacttctgcatcattcactgcag tccctggagtccataatgaagtgtgtgcacatgagctggatggtgatcctggtgggccca gcagctgttggcaaaaccagtctggtggagctgttggcccacctcaccggccaccagctg aagatcatggcgatgaacagcgcaatggatacgactgaactcctgggtggatttgagcag gttgatatcaacaggccgtggcagcgcctcctggaaaaagtggagcatgctgtgagcaca cttgtaagggacggtctgctcctggcagaactttgtgcagatgatgctgagctcctgctg cgtgcttggagcaatttcatcctgaattacaaacccaaatctctgggggaaggaggtgga agggttacagctgaactagtgagcaagctggagggaatacttgtacttacccagcgacta aacaacaaaataaattcttacacaaaggcggagtttgctcacctggtagaagagttccgg catttcaagctgcagcaggcccaggctgctgactgcaaaagccatggcacttttgagtgg gtagatgggatgctggttcaggccctgcaatctggagactggctcttgatggacaatgtt aatttctgcaacccttctgtgctggaccgcttgaatgctttgcttgaaccaggaggtgtt ctgaccatgagtgagagaggtgtcatagatggcacgattcctacaatagctcctcatcct aacttcaggctgttcctttctatggatccagttcatggggaaatatccagagccatgcgg aatcgtgggattgaaatttacattcctggggagaatgatggaaatatgttggacagtctg gatttgaagctgctcctgcatggtttgggtttagttggagatagtgtctgtgatgcactt ctggctgtgcattcagaaaccaaggcagcaatagcaggttccgtgtcatctttgtcacct ttgcttcaggctgctgtattaattgtgcagcaaatacaaagaggctttggattagcgaag tctttttacagagcctgttgggaagtttatggtcgctcacaacaactgcaaatcaaccaa aagcttgtgttagaattggtaacgaggcatgcttcctctctggcttcccctgacacttgg ggtgagtccttgctagcagtgggattgtggccagactccctgccttcgggtctgtttgca gctgaagactcactcctttccacagtccagagtgatggacaggtcctgatgtattgtctg catagactaaacctcagaaactgcaggacattaccagtgactctgcaagatcttaagaaa gttatgcagtccactaatcccgagagtctcaagttcagtgctgtagagatagatccaaac tggatggacaaaatggaagttctccaggcttcagtgaaattttttatagcaaaggcaacc aatcaagattggaaattaagagttaaatggcttaactccttagccaaaaatctgccacag gtgcttgattcagtgcggattcagctggaagcaagtgctgtagcccttggctgtttctat gccagtcccctctcatctggagtcagtaacatgatcaagttgctacagccgactatgaca gatgaacatgtgatgcctctggatccaagatggaatatgcagtttttggagatcattaga aattcagtgaactttgatacagaaatggaacatgcagaccagcttcttatgcttttgaag tctgcagcaaatcgggcagtgttatttcttgaccgagaaaaaagaagttacattgagaag agtttgattgccagcaaaaagccaagaaacagtgtcttaggaatgtctctagagttccac aaaaatccaggaagttacagcagtcttcctcatggaatcgtggtcaaccttgctgctttc tttgaactttgggatgcatttgtacttcactgggtgaagaatactcaggtggccttaagt gacgatgacatgcatgatgttttgtactgctggctgtggcgggaccggttctgggctgtc tctgacactgtaacagcagattcaccagggctgtcactcctggctctgcactggcactgg gttatgaaacacctaattgacagaattcctcagatgcttattggatcagaccagaacaaa atttctagggaaattcaatctgtttcacagcagattcagaactgcttggtcaatcctgct ggtatttcagccaatatgaagatactacagaagtctctaggaagaccccttccttttaag gataaactgggaatggaatgtttttctcagttaaaagctctcagcaaaccactgaacatc ttggagctaagatcagcatgtggagaaagtagatggcaggaaaaaatgtgctgtgtgaaa attgctgccacaggagtgaagatgaagaaagcattgctgcaggctgatggcctgataata agagccaatcatttagaagatgttagtctgggtgagctacagatatttttggaagctgta cattcacagctgaaagcagaaggagtcacatatagttattctgaagaaaggcttcctgaa gacatcatctccaaacagttagaccctgccttactaaaccatctttgtagtcaggttcag atgtggcctgcaatggaatacataggggtgctctggcagtacaaactaacagcagattat gtggccaaggcttgtgcaagaaggaagaactgcagtcaagagttaagtgtctgttcagat ctagctcagttcatagctttttctctgcagctgacaccagctgcttctcaccagctctct ggactgtggcacttgttacaccttaatgaaatatcccctgaagaaatgtctcttctgtca tctcagctagttaatgctgttttagcatccttttggagcagtactttcaccatggaccca gactattggttgacttggaggccactgcctgcaacagaggaaaacaacttctctaaatcc catgtgaaccgctctatgaagggcccaggcattttgacccgagctgttttctcaaagtgc ttctttgaaattctaactagcagcagcaagacaagccagtgggatgtgagtgggcttcct gtcttgtcatcatcccatgtaacactgggagaatggatggagagagcacagcagcttcac aaagtcagcacagcactgtggaccaacctggctgtctcttcaatggcagattttagacaa acagatgctagactgcaaggagtaatgctaagcagacagctctctgccctggtgcatctg attccagtggctcttcaagaggaatttttggagtgctgtgagaagctctacctcaaggat gctgttgcatatgagtaccttctcaagatacttgaaagcatcactgatcaggaattactt cctaaagaattcctatttcttctgatcacttgcttgcatcagttctatggggaagggctt caggagttaccagagacagcttggcgtggaagcctctgggtgagccttggcttggtgcag atccagatgtggcttccacagaccaggtttgatccagctgttaaaagagaatacaagctc aagtactcaaaagaagagttataccagctggagtgtgaatggaaaacacatgatttttca tctgagctacatacaggaaaaagtattgaagatgaaacagtcagcaactatattcatccc catatcaggctgttgcatgaaagaatgcaaaggttgaaggagcaaattagcagcctttcc agaaggaaggccttcaggcccccagctccactgtatgattgcttataccaggaggctcat cagtacatcaacagcatagcacagatttcctcagtccaagaccttctagcccgccttctg cagttcctccgtggagagagacctaaatcactgcaagccatacagaacctgttaagtgaa gaggcatcgtggcaacaatcacaccatcagtttagaaagcacctggcagaggagtatgct gtattccctgatgccatcattcccctccaagctgccatcctgcagctgcaacatggcatg cgattagtggcttctgaagcgtatgcagtgctgcagagctctgtgtgcccagctgatctc accaacctcctcacttctttgctggcattcccttctgttggccgtgcctttcccacttac ttttctcgggcagaagttttatgctcagtgaattcagttggggtacttaatggacttaaa aagttctctctgaagcactctgaaggaggatctgagggaggtgagcagccttcccctact ctggaacagcttctggtgaatgctttgttgcatcttcgatgtcatgtgctatccagagga gaaatggaccagaaatctctgcagctcttcagacatctgtttcgggcgattgtaaatgaa tgggatgaacaggaacgccgtgcccaagagcaggaggcaatggaacgcagcctgtacaga tacaggagtaaaagtcatgggaaaggacggagcgaggaagaagaggaagaagaagaattt aagaggagatttccctttcatgaaaaggactttgaagatatcacagctcagccaagccta gaagaaaaaatggaaactgaagacccagtggaagaccagctggaagttgacagagccctt ttgtccaaaagctctatgcaaacagtaatgaaggttcatcagcagttgtgcttaaacttt gctcgatccctgtggtatcaacagagtatggcttctcatcaagccaagcattatttcagt acatttatttcctgctatcagactggtgcatgcctggtgtcacaattctatcctttaatg ggtgctgaaatgaatgacagtcttttgggaagccaacttctgctgagcactcttcttcac aataccttttttgaggaagtaacttcagatcttgtgcttcagcaagatggtccttacgac ttctatcagcatcccaatattcagcaagtccgacagtgccaacctgtacttgacaatttt gctaaagaaataaatgggctactgcaggaatggccagagcatcctgtacttgtacagctg ttagttgtgatggacagaatccggagttttcctctttctagtcctctctcaaagtttctg aatggcttggaaattcttcttgcaaaggcacaggactgggaggagaatgcttgtcgggcc ttgtccttgcggaagcatcttgatctggtcacacaactgattattcagtggcgcagattg gagttgaactgctggtcagtaagtttggacaacattatgaagcagcatgtggacaaatcc acaaagtactggttctcaatctatcagatgattgagaagtatgttcaagaacagacagag gcaaacacagaaggagctgagcaaatggatctgaaaacgctggtcagcacattacaggct ttcattgaaggctctactctgggagagttccatgcacggctccaagtactgttggttttc cactgccatgtcttgctgatgcctcaagtagcagaaaaggatgttctgtgcagcatcctg tggaatctgtacaattactataagcagttttcagagtgtgttgaggccaaaattgctgac cttcgtcagcccatagaaaaggaacttaaggagtttgtgaagatttccaggtggaatgat gtcagcttctgggctataaaacaatcagttgaaaaaatacgcagaactctctttaaattc atgaagaagtttgaagttgttctgaatgagccatgtcagcctgccctggtggaaattggt aaggaagagcagctggactgcatgcaaaagcaagaagaatctgacgacaaagaaaccaaa attcagcggctaaacaacacattaagaaaggttctgtctgctagaacagatgttaccaag agggcactcccagaatgtcagggtgtcattacatttcatacagaatctcttcagtatcgt ctgtccaagctgacgaaaaaaatgaagaaaatgtgttcagcagttacagaaaataattca ttattaaacctggtggaaaatctcgaccaattcacaggtggtattattgtttctgtagct gaactgcaaaatttaacatttgatcagacagcaactaaggagaagcagaaatcagaggca aagcatatccagatgcaaaagcaacgggctttgtcggatctctttaaaagccttgctaaa acaggtttgtcataccggaaaggtctgtcttggtcccgttcaaaagattgccaggaagtt ctctaccttcgtccactggacttgtgtagtgcattggctgcagtgaattgtacacatgaa ctggatgccacgttgctgacagagatttcttgtgcctgggatggatgccagaagtacttc tatcggtcgcttgcacgtcactctcggctccagacagcattgttagcacctgccaaggat attggactaggtagcattgaacgatgcaaagggttcactgcacacctcatgcagatgctt gtgagacagaggcgatctcttactgcactgacagaacagtggatcttactcaggaacctt ctgagttgtatacaagaaatagattctaggttgactgctgacagagaatacagtgcagcg tttcctcctcaagacagtattcaacgctggacagacagactgcagcagctttgcatgcag tgtgtgatggttctcgaggagctgtcttggtttatccagtgctgcccaaaagaagagtca gccaggcccaatgacagtgaaaggaccgatgtcaaagacagcattcctcagagttcagta cctgaaatgggaaatgttcttgcgagaatacctgacctgattccctcagatctaaaacac ctgtctccagtaacaattgagcaattgcctcctggatgcaggatgcgaaataaggatcag ttgtgggtgcaggtatctacacaattgactgcaatgacggcagatgtgaaggccgtgaaa gcagaagtggacagagtaagacagcagtcacgggaaacctcctttcattcctggagagac tttgaagtttgcacatcagctgtgagctgtttgctggaagtctcagcccagttacaaagc atagagtccctgttccttccaaatgggcaagacagcgaagctgcaaatcagatggcccta atcaagagcctaaagtatatacaagaagtcatcagtaacacatcctcagacttcacagtc tggagaacacagcttcttgcttctgtgtcagattgcacaggaaatcaacagtcggatgaa gagtttgtggaacaattctcaacaaaagtggaagccgttatccgtgctgttctgtatgct gttcagtgtttggtagagagaaaacaggaaggtggaaaagaggaggaaaaatcttcagag gaaaatgaggatgcagccttacttgatgtgattaaagccggacatataactaaacttttg tatgaagatctgtctgctgatttggagtctttacatgtgcagaaggcaattttaggtgtt tcagaactcctggagatcctgaaatcttacagggaagactgcacttcatataaacataag ttcttcaaccagtcctgctatttgctggtgcgtctaaagcccatgctctgcaagtattca gacctcatcctgttctacctcaccgtttcactggcatctcataggagtactggaaaactg ctttctgttctaaccagcatttttacagagcttgctctaaaggggttttgtctgccaaaa gaattacttgaagatgaagcaggagagggagcaacagagttccatgactatgaggatggt ggtattggagaaggggaaggcaagaaggatgtgagcgacaaaatagaaagtgaagatcag atagaagacagttttcgaaaaggtgaagagaaggagaaagaggatcaagattctaaacca gacattgaaggagaagacaatgcaattgaaatgtctgaagactttgaaggaaagatgcat gatggagaaatggagaaaaaagaagatgaggaaaattcagatgaagaggaggaactggat aagcagatgggcaatcttgataatgctgaagccgatgataaactagatgaaaggctctgg ggggatgaagatgatgatgatgatgatgaagatactagtagtaaaacagaagaaactgga ccaggaatggatgaggaggattcagagctcgttgcaaaagatgacaatctggggacagga aacaaagataataaaaaacagcctcccaagaataaggaaaaagagcaagaggaagaggac tgtggaaatacagagaaaatccatgaacaaattgatgagcgtgagtatgatgagaatgaa gtagatccttatcatggccagcaagaaaaggagcctgaagttgaacctttggaccttcct gatgacttgaatctggagagtaatgaaaagagtgatgatgaggatgaagaagaagagaat gattttgaaagagatgagaaacctgtggatttcaatgaagcagagaagacggaagaacag aatgaagaaaatactggtgagacagaaaaagatgagcaagatgcaaaagcagctgaagaa ggcatttctgaagacaaagaggagaaggaagatgaaggagacaaagatgctcatgatcaa gaagaaaagccagggaacactgaggatgcagaagaagaagaggaagagtcacaaccacct gatgataaaaaaaatgaatctgctgaagataagggaatccctaatgaagaccagggcctt caacctcaggaagaggaggataaagataattcagagacggatgaacagatccctgaggct gaggaaagaatggagcatgaaacacaagggcagactgggcaagaaaatctgcagagtgac agtgctgttgagctggctggagaggcttcagaaaaagatgagtctagagaggaaagtgga actggagcttcaagtgcaaaccagtcagaaggccatgaatccacatgcatggcccggatg gcttctgagaagcaaagcagaaaaaatacacagagtttcaagaggaaacctggccaggca gacaacgagcgctcaatgggagatcacaacgaacgcgtccacaagcgattgagaaccatg gaatccagcagtgaagcaaagcaggatacaactcagcctaaacaaagcgtagaggaggct gatgcatttgaacatattaaacaaggctctgaacactatgatgcacagacatatgatgta gctagcaaggagcaagagaaacctattatacctcctgaagaaaaggaagaaggagactgt gaagatgtagcaatggaaacagaaatgcaggacgaggatctcagagcagtagacactgaa gagctgaagccagagaaaaagaagtctactgccactaaacctcctggaccaggtgatgtg gagccagagctccagacttttgactcagaggatgtcaatgaatctgcaccagaaaaacta ctaaaggtgactgaagagaagccagagagaagcaaggactcaaccatacacacagcccac cagtttctgatggacattccccagcacatcattagagatcctgaagagctaagaaaggaa cttgaaaggcagttggaagcttggcagacacaacagcctggaactccagaggaggagaag gaagcagcacagctgtggcagaagtatttagtcctgacagctcctctatcacagcagctt tgtgaacagctgcgactcatactagaacccactcaggctgccaagttgaaaggagactac agaacagggaagagactgaacatgcgcaaagtgatcccatacattgccagtcagttccga aaagacaagatctggctgcgaaggaccaagcccagtaaacgacagtaccagatttgccta gctattgatgattcctctagtatgattgacaatcactccaaacagcttgcatatgaatcc ctggcagttattggaaatgctctgactcttctagaagtgggacaaattgctgtgtgtagc tttggagagactgttcagctgctgcacccattccatgagcagttcagtgaccagtcaggg acacggatattgcgtctttgcaagtttcagcagaagaaaacaaaaatagcccagtttcta gaatcatcagcaaatatgtttgctgcagcacagcagttgtctcaaaatattaatccggaa acagcgcagctgcttttgattgtgtctgatggaagaggccttttcttggaaggcaaggaa cgggtgacagcagcagttcaagcagctcggaatgccaatatctttgttattttcgtagtg ttggacaaccctaattcccgggattctattttggacattaaagtacctatattcaaagga cctggagaattgcctgaaatcaggtcttacatggaagaattcccattcccgttctacatg atccttagggatgttaacgccctcccagaaactctgagtgatgccctcagacagtggttt gaactggtgactgcctccgacactctttag

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