Parus major (Great Tit): 107204473 Help Entry 107204473         CDS       T04864                                  Symbol PCLO Name (RefSeq) protein piccolo isoform X1   KO K16882   protein piccolo Organism pmaj  Parus major (Great Tit) Brite KEGG Orthology (KO) [BR:pmaj00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pmaj04131]     107204473 (PCLO) Membrane trafficking [BR:pmaj04131]  Exocytosis   Calcium ion-dependent exocytosis    Others     107204473 (PCLO) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-piccolo C2 PDZ FYVE_2 IBR Motif Other DBs NCBI-GeneID:  107204473 NCBI-ProteinID:  XP_015483139 Ensembl:  ENSPMJG00000002596 LinkDB All DBs Position 1A:8445393..8759535 Genome browser AA seq 5231 aa AA seqDB search MGNEASLEGGEGLGAFPEGAAAAGDGGGPAPPLQSLVPAGVEADLSKLSEEERRQIAAVM SRAQGLPRGNLAGAEPPPMQRHPELDTSRHPRQPGKPPDPGPPGLSKSRTVDVLKTEQRA PGRSPSTLSLRESKSRTDFKEDQKPSMMPSFLSEANPLSAVTSVVNKFNPFDLISDSDTT HEEAGRKQKVAPKEQGKPEEQRSPAKHPAQPQTPKPAGQQGPVRPTVQQTESSKPVPQQQ QPGEPKQVQKPGHGQPADAKQEQAKQPPQPRGPQKTQPQPSEPTKPVQQQASAKPSSGPT KPSPQQPDSTKTTSQVPPPTKPSSHQPGPAKQPSQQPAWQGGPVKPSSQQAGPPKQPSQQ PGPEKPSAQQTGPAKQPPQPGSGKPPLQQTGLAKQVPPQAGPTKPPSQTAGPTKAPAQQA GPTKPPGQQPGPDKPPQQKQAGASQPTESAPKKTFCPLCTTTELLLHTPEKANYNTCTQC HTVVCSLCGFNPNPHITEISEWLCLNCQVQRTLGGDLAPGLGPGPQPPAPKQKTPIPPST AKPSPQPQPVQKKDVTPKPDPSQLADSKKPPPQKKQTPLPGSPPVKSKQPRAEPTDTSQQ IDATPKSDQVKPMQAEEKQKQASVQKPAADTVSTSAAPEQKQDLAGPRPPTQQKVTDSPK PELAKPSQDTHPAGDKPDSKPVPQVSRQKSDPKLASQPGARADAKAPKPVEPTQTKDDLK KLPTKPAPKPDTKPAPKGPQAGAGPKPVPAQPAPQPQPPQKTPEQSRRFSLNLGGITDAP KPQPTTPQETVTGKLFGFGASFFSQASNLISTAGQTGSQTSGPPPPGPAAKQPQPPTQPP ALQAAPKEPSQAQPLPKAVPVKKEAKPLTAEKSEPSKVDSVLTKGSDLEKKPGLAKDSKP QAAEARKPDGLLEPEKASQPEMSCPLCKTGLNIGSKDPPNFNTCTECKKVVCNLCGFNPM PHIAEVQEWLCLNCQTQRAVSGQLGDMGKMPLPKTGPSQPTSKPPAPPQKRPVPAVSHSP QKTSTPPTPAAAKPKEEPGIQKEAPKHLQGRLEKTLSADKIQQGIQKEDAKPKQGKLVKT PSADKIQHASQKEDPRIQQTKLTKAASYDRVLHEVQKEDEKLQEAKLAKTSSADKILHGV QKEDVKLQEAKLAKMPSADKILQGVQKEDPKLQQMKMAKALSADKIQPAAQREDTKPQEI KLPKAASIDKIQHGIQKDIKLQHEKIKKTSSVDKIQEEGQKEETKLQRGKLSKTPSADKI PTITTADQKKPLSMLEEDKETVLPEKSTTHPEDKKKEITVEIKDHAAEKKADIEAPYEGL QAKEQDVKKEDLTTGISQEILKAEKAQEEEIPVQTAPLPGTDHVEAVREKIEKEDEKSDT SSSQQQKSPQGLSDTGYSSDGISSSLGEIPSHIPTDEKDLLKESNKKEPVSQESPPSPSD LAKLESTVLSILEAQASTLSDEKSEKRKELSETYGEQTKDQLKTKLLPVTLESYSSDEED LKAIKEGEGTIAEEGKGTASSRADYKEEHEGDDISARRQQRYDSVEDSSESENSPVPRRK RRTSVGSSSSDEYKRDDSQGSGDEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISAA ESQRKEEMKSKAKGTAGKHRRMARKSSAGYDEDAGRRHSWHDDDDETFDESPEPKYRESK SQDSEELAVSGGGGLRRFKTIELNSTITNKYSEVSEQQKGILYFDEEPELEMESLTDSPE DRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKLGGESKQQRKARHRTHGPLL PTIEDSSEEEELREEEELLKEQEKQRELEQQQRKSSSKKSKKDKDELRAQRRRERPKTPP SNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESEPEGFEISPEKIIEVQKVYKLP TAVSLYSPTDEQSTGLPKEESGQKTLKSAEEVYEEMMHKSKSFQMSNEKDEVFEKESLYG GMLIEDYIYESLVEDTYNATIDTNLVMRQDESSEYIQQRGKEKKPRASEQVYDEPEKISD LEKDYYGVETLHTIVPQEDIVSSSYIIPESHEIVVLDSTVTSTIEEKHLLDAEAAYEELM KRQKMQLTPGSSPTQPASDLIPTSDTKGLGGAEIVDSTSLTSSTTSAISDVSPVSSTTLS IPDVKITQHFTAEEIEDEYLTDYAREIQEIISHETSILTYSETSEGAASVLPSDTASLTS STSSVCTTDSSSPIDSATTGFVGPADGVSKPADSEGDRIITQVPLTSAKEYSEVSMPYES IAGATKKPTLESDAESVEKMAVCLPETVPLVVAPTVTKSKEYAADTIIFDTSKAEKEAAR KAKSTVEAVSVKIHHEEPHKELGVDMTRIDLTNAASEQPPICITPIPVSEPASETSVLTH SVVSKTSMVSVPSSAPAVSAKVFSLFRSSSLDSSTHPSPPPPPPPPPPPPPPLPPPPILP KPAIYPKKKPQIKAPAATAPTVVPPVTSVPTLESIAVLKDHVVPVTKTYTPTPPPVPPKP SSIPAGLVFSHRPPEVTKPPIAPKPAVPPLPISVHKPAEIQPKPVSLSLTSSMTLNLVST AEYKIPSPTSPLSPHSNKSSPRLAKPSQETYVVITLPSEPGTPTEAITSQAVTSWPLEEP SKEQIPQPMQPVFTTSMKTMDIQSMAGQSMYISGALQAIPVTTQSTFEKIPTSKSVVATT DITKTTVSVVKGPVPGYGLGSVAITIPPEPLHIVDQPRYRENGRFHPLGDVIDLRTLTKM DIEMRDSCMDLSAVSMDVRRQMPASDTSGRPVSTVQPSIINLSTACVADTSLPVVTETVT VMTCTATVSYTTSTDSLVDLGHAMTTPLQLTTSKHFEPAYRVTGSQAFSVGRDEVPINLS LGTSAQAVTWAATKPVTVPPVGVTNGWTDLSTSQEPAESGAVDLSTTKSHRTVVTMDDTS SGIVTTVIEDDEKPVDLTAGRRAVCCDMVYKLPFGRSCTAQQPSTTLPEDRFGYRDDHYQ YDRSGSYGYRGIGGMKPSMSDTNLSEAGLFAYRSKNSFDYRVGATDTAVDLTSGRVTTGE VMDYSSKTTGPYPETRQISGLGLSTPQYSQARMVSSVGSQFGVGSVLRSSNGVVYSSVAT PIPSTFAITTQPGSIFSTSVRDLPTLQTIDSVPSLSTLQQTQPLPRSYSFLTTVAAEKDK AITAVGMETGLPPHSIETITTEPTSLIPALTTASEVYTDVIDDEVALLIAPEEGKQQQLD LERELLELEKIKQQRFAEELEWERQEIQRFREQEKFMVQKKLEELQSMKHHLLFQQEEER QAQFMMRQETLAQQQLQLEQFQQLQQQLHQQLEEQKLRQIYQYGYDPSGTGSPQTTTDQT LLEGQYASTENGQFWPTDDTTTTASGVLGIEIPQSQTWYTVQSDGITQYIPRSGILSSVS EMSLKDIDVREEKQLKKRSSMPKLRGPYEEFEETLEEEPRCFKKIVDSGVQTDDEDGADR GYTNRRRRSKKSVDTSVQTDDEDQDEWDLSSRSRRKPRVGKYSESTTEADKAKPFSKVSS IAVQTVAEISVQTEPVGTIRTPSIRARWDAKVEIIKHISAPEKTYKGESLGCQTETASDT QSPQYLSASSPQKDKKRPTPLEIGYSSHLRPDSTLQVVPSPPKSPKVLYSPISPVSPSKV IESAFVPYEKPMTDDISPQKMLHADMAKVPPSSPKAAKMMQRSMSDPKPLSPTAEDSSRA QFQYTEGFMSKGSSSMTPSSTQKKVKRTLPNPPPEEATAGTQSPYTSVGSVSRRRICRTT TMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKE REKRERAYLQGVAEERDYMSDSEVNNTRSTRIETQHGLERPRTAPQTEFNQFIPPQTQPE TQFAPATSPYAQYQYSSPALPTQAPTQFTQQSHYQQQQPLYHQQVSPYQTQTAFQTGATM SFTPQAQPPPSQQPSYQLPSQMMVIQPKPRQTTLYLEPKITTNYDVIRNQPLMIAPVSTD NTYAVSQLGSKYSTLDLRIGLDERNSIASSPISSISADSFYADIDHHHTPRNYVLIDDIG ELTKGTGTLGSSFSLHEKDLTKTDRLLRTTEARRAQEVSDFLAPLQTSSRLHSYVKADED PMEDPYELKLLKHQIKQEFRRGAESLDHLAGLSQYYHGEGSYRHFPKSEKYSIGRLTLEK QAAKQLPAALLYQKQSKHKKALIDPKLTKFSPIQESRDLEPDYSSYMTSSTSTLGGITTR ARLLQDDITYGLRKNISDQQKYMGPPLTSSIGAGLGTALGPTMRATLQDEADKSYSSGSR SRPSSRPSSVYGLDLSLKRDSSSSSLRLKAQEAEPLDVSFSHAAPSGRTKPTSLPISQSR GRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREE SRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPREPRLENGHILDRRLPEKLS HSRPLSQHQDQINGKPLQYIFPHTRLKLLRDPKDHTVSGNGLGIRVVGGKEIPGSSGEIG AYIAKILPGGNAEQTGKLIEGMQVLEWNGIPLTGKTYEEVQSIIIQQSGEAEICVRLDLN MLSDSENPQHLELHEPVRAVDKAKSPGVDPKQLAAELQKVSLQQSPLVASSGVEKGSHVH SGTASATSSAVPSPGQPGSPSVSKKRHSSKPTETTKPASHPITGEIQLQISYDKHLGNLI IHILQARNLAPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYIQKSLNPEWNQ TVIYKNISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIELSSISQLDNTPRWYPLKEQSE NIDHGKSHSEKSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHL RSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRLQPTAHKSGQSNHARKQHRHSIA GVLPIQRTQSDNLPPPANDNKDQSQLALRKVMSDGPVKPEGARSTNHRPAESSVSTGSSA SSFGSGYSMDSEGSSSATGENNLFPIPRIGKMSQNGQEPVKQSGVGVTDSEGKTQVMGEI KIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKLYVVNISTQKRVIKKKTRV CRHDREPSFNETFRFSLSPAGHSLQILLVSNGGKFMKKTLIGEAYIWLDKVDLRKRIVNW HKLLVSSTQTH NT seq 15696 nt NT seq  +upstreamnt  +downstreamnt atgggcaacgaggcgagcctggaaggaggcgaagggctgggcgccttccccgaaggggcg gcggcagccggggatggcggcggccccgcgccccccttgcagagcctggtcccggccggg gtggaggcggacctgagcaagctgagcgaggaggagaggaggcagatcgccgctgtcatg tcaagggcgcaggggctgcccagagggaacctcgccggcgcggagccgcctcccatgcaa agacatcctgaacttgatacaagccgccatcccagacaaccaggtaagcctccagatcca ggaccaccaggattgagtaaaagcagaaccgtagatgtgctgaagacagaacaacgggca cctggacggagcccttctactcttagtctacgagaatcaaagtccaggactgattttaaa gaagatcagaagccaagtatgatgcccagttttctctcagaagccaatccgttgagtgca gtcacttctgttgtgaacaaattcaatccttttgatttaatatcagattcagatacaact catgaagaagccggtaggaaacaaaaagttgccccaaaagagcaagggaaacctgaagag cagaggagccctgcgaaacatccagctcaaccacagactccaaagccagctggtcaacaa ggacctgtcagacctactgtccaacaaactgagtcttccaagccagtgcctcagcagcag cagcctggggaaccaaagcaagttcagaaaccaggccatggccaaccagcagatgctaag caagagcaagcgaaacaaccaccccagccgagaggaccacaaaaaactcagccacaaccg tcagaaccaacgaaacctgttcagcaacaagcttctgcaaaaccttcatcaggcccaaca aaaccatctccacagcaaccagacagcactaaaacaacatcccaagtaccacctcccaca aaaccatcatcacatcagccaggacctgcgaaacaaccatcgcaacagcctgcatggcaa ggaggtcctgtgaagccatcttcccagcaggcagggcctccaaaacagccttctcagcag cctggacctgaaaagccatctgctcagcaaacaggacctgcaaaacaaccacctcagcct ggatctgggaagccacctctgcagcaaacagggcttgcaaaacaagtgccaccccaggca gggcctacgaaaccaccctctcagactgcagggcccacaaaagctccggcacagcaagca ggacctacaaaaccgcccggccagcagccagggcctgacaaacccccgcagcaaaagcaa gctggtgcaagtcaacccaccgagtctgccccaaagaaaaccttctgccctctttgtaca accaccgagctgctgctgcacactcctgaaaaggccaactacaacacatgcacccagtgt cacactgtagtctgcagcctgtgtggattcaatcctaatcctcatatcacagagatcagc gagtggctctgtttaaactgccaggtgcaaagaacattaggaggtgacttagcaccaggt cttggtcctgggccacagccacctgcacccaaacagaagacacccattccaccttcaaca gccaaaccatctccccagccacagcctgttcaaaagaaagatgtaactccaaaacctgat ccttcacagttagcagattcgaagaaacctccgccacaaaaaaagcaaacacccttgcct gggtctcctcctgtaaaatcaaaacagccccgtgcagagcccactgatacctcccagcaa atagatgccactccaaaatctgatcaggtcaagccaatgcaggctgaagaaaagcaaaaa caagccagtgttcagaagcctgcagcagacactgtatctacctctgctgcaccagagcag aagcaggacttggcaggccccagaccaccaactcaacagaaagtgacagactccccaaag cctgagcttgcaaagccatcacaggacacacatccagctggggataaaccagattccaaa cctgttccacaagtgtcccggcagaagtcagaccccaagcttgcatctcagcctggggct agagcagatgctaaagctccaaagcctgttgagccaacacaaacaaaagatgatcttaaa aagttaccaacaaaaccagccccaaagcctgatacaaaaccagctcccaaggggccacaa gcaggggcaggacccaagccagtgccagcacagccggcacctcagccccagccacctcag aaaactcctgagcagtcgaggcgtttcagccttaacctggggggcatcactgatgcccct aagcctcagcctacaacaccacaagaaacagttactgggaaactctttggatttggagct tcattcttcagccaggcctcaaatttgatttccacagcgggtcagacaggttctcagaca tcgggcccccctccgcctggtcctgcagcaaagcagccccagcctccaacacagcctcca gcccttcaagcagcccccaaagagcctagtcaggcacagcctcttccaaaagctgttcct gtaaagaaagaagccaagcctcttacagctgaaaaatcagagccgtcaaaagtggatagt gttttaactaaaggatctgatttggaaaagaaacctggtttggctaaagatagcaagcct caggctgctgaagctaggaaacctgatgggctgttggaaccagagaaagctagccaacct gaaatgtcttgtcccctttgtaaaactggactaaatattggttctaaggatcctcccaac tttaatacctgtaccgagtgcaagaaagtcgtgtgcaatctctgtggatttaacccaatg ccacacatagctgaggtacaggaatggctgtgcttaaactgccagacccaaagggcagtg tcaggacaacttggagatatgggcaagatgccacttccgaaaacaggcccttcacaacca acatccaaaccacctgctcctcctcaaaaacggcctgtgcctgctgtctcacattcccct cagaaaacttccacaccacctactccagcagcagcaaagccaaaggaagaaccaggcatt cagaaggaagctccaaaacatctgcaggggagattggaaaaaacattgtcagctgataaa atccagcaaggaattcaaaaggaagatgcaaaacctaagcagggaaaacttgtcaagaca ccctcagctgataaaatccagcatgcttctcagaaagaagacccaaggattcagcaaaca aaactgacaaaggcagcctcctatgacagagttttgcatgaagttcagaaggaggatgaa aaacttcaagaagcaaagctggcaaaaacatcctcagctgataaaattttgcatggagtt cagaaggaagacgtaaaacttcaagaggcaaaattggcaaagatgccctcagctgacaaa attttacagggagttcagaaagaagacccaaaactccaacagatgaaaatggcaaaggca ctgtcagctgacaaaatccaacctgcagctcagagggaagatacaaaacctcaggagata aaattgccaaaggcagcttcaattgataaaattcagcatggaattcagaaagatataaag cttcaacatgaaaaaattaagaaaacttcatcagtggataaaatccaagaggaaggtcaa aaagaagaaacaaaacttcagcgagggaaactgtcaaagactccttcagcagataaaatt cctacaataacaactgcagaccaaaagaaacccctaagcatgctggaagaagacaaagaa actgtgctcccagaaaagagcacaacacatccagaagacaaaaagaaagaaattacagtt gagattaaagaccatgctgctgaaaagaaagcagacattgaagcaccttatgagggactg caggctaaggagcaagatgttaagaaagaggatttgacaactgggatttcacaagagatt ttgaaagctgaaaaagctcaggaagaagaaattcctgttcaaacagcacctttgccagga accgaccacgtggaagcagttcgagaaaaaatagaaaaggaggatgaaaaatcagacaca tcaagctctcagcaacagaaaagtccacaaggtctgagtgacaccgggtattcttctgac gggatatcaagttcacttggtgaaattccaagtcatatccccactgatgaaaaggattta ctcaaagaatctaataaaaaagaacctgtttcacaagaaagtccaccaagcccctcagat ctagctaaattggaaagtacagtactctcaattttagaagctcaggcaagcactctttct gatgaaaaatctgaaaaaagaaaagagctttctgaaacatatggcgaacagacaaaggat caacttaaaacaaagcttttgcccgtcactctggaatcttacagttcagatgaggaagac ttaaaagctatcaaagaaggtgaaggaaccattgcagaagagggcaaaggaactgcttcc tcccgggcagactacaaggaagaacatgaaggagatgacatatcagcaaggagacaacaa cgctatgactctgtggaagacagcagtgagagtgaaaactcacctgtcccgaggagaaaa agaagaactagtgttggttcttcaagcagcgatgagtacaaacgagatgacagtcaggga tcaggtgatgaagaagacttcattagaaagcagattatagagatgagtgctgatgaagat gcttcaggttctgaagatgatgaattcattagaaatcaactcaaggagatcagtgcagct gaaagccaaaggaaagaagaaatgaaaagcaaagccaaaggaacagctggaaaacacaga agaatggcacggaaaagcagtgcaggctatgatgaggatgcaggaagaagacattcatgg catgatgatgatgatgagacttttgatgaaagccccgagccaaaatacagggaaagtaaa agtcaagacagtgaagaacttgcagtatctggaggaggaggtcttcgacgtttcaaaaca atagaactaaatagtacaataacaaacaaatattctgaagtatctgaacaacagaaaggt attttatattttgatgaggagcctgagctagagatggagagtcttacagattcaccagaa gatcgatctagaggagaaggatcttctagtttacatgcttctagtttcacaccaggtaca tctcctacttcagtgtcatcacttgacgaagacagtgacagcagtcctagtcacaaaaaa ctgggaggagagagcaaacaacagcgcaaagcaaggcatcgaacacatggtcctcttctt cccactattgaagattcttcagaagaagaagaactacgggaagaggaagagctgctaaag gaacaagagaaacaacgtgaattagaacagcaacaaagaaaaagttctagcaaaaagtct aaaaaggacaaggatgaactcagagcccagagaagaagggaacgtccaaagacaccgcca agtaatctttctcccattgaagatgcatctccaacagaagaattacgacaggctgcagaa atggaagagctgcacagatcttcttgttctgaatattcacccagcattgagtcagaacct gaaggttttgaaatcagcccagaaaaaataatagaagtgcaaaaagtttacaaattgcct actgctgtctctctatactcaccaacagatgaacaatcaactggactcccaaaagaagag agtggtcaaaagacattaaaaagtgctgaagaggtatatgaggagatgatgcataagtcc aaatcatttcaaatgtcaaatgaaaaagatgaagtatttgaaaaagaatctttatacggt ggaatgctaatagaggattatatttatgaatctttagtagaggatacttacaatgcaact attgatactaatctcgttatgagacaagatgagagcagtgaatatatacagcagcgagga aaagagaaaaaaccaagagcttcagaacaggtctatgatgaaccagagaaaattagtgat ctagagaaagactactatggtgttgagacattacatactattgtgcctcaagaagatatt gtttctagttcttatattatcccagaaagtcatgaaatagttgtattagacagcacagta acttccaccattgaggaaaagcatttgttagatgcagaagctgcttatgaagagcttatg aaaagacagaaaatgcagctaacccctgggtcaagtccaacacagccagcttcagattta attcccacatctgatacaaagggattgggtggtgcagaaatagtggatagtacatcttta acatcaagcactacttcagcaatctcagatgtatcaccggtcagtagcacaacactttct attccagatgttaaaataacacagcattttacagcagaggaaattgaagatgaatactta acagattatgccagagaaattcaagaaataatttctcatgagacatcaatattgacatac tctgagacatcagaaggtgctgcatcagttttaccttctgatacagcttccttaacatca tctacatcttcagtttgtaccacagatagttcctcacctatagatagtgcaaccacaggt tttgtaggtccagcagatggtgtaagtaaaccagcagattctgaaggtgacaggataata acacaggttcccttaacatctgcaaaagagtactctgaagtgagcatgccttatgaatct attgccggagccacaaaaaaaccaactcttgaatcagatgcagagagtgtggagaaaatg gcagtttgtttgcctgaaactgtacctttagtagtggcacctacagttacaaaatccaag gaatatgcagctgataccataatctttgatacctccaaagcagagaaggaagcagctaga aaagctaaaagtacagtagaggctgtcagtgtcaaaattcatcatgaagagccacacaaa gaattgggtgttgatatgacaaggattgatttgactaatgctgcatctgagcaaccacct atatgtataacaccaataccagtttcagagcctgcatcagaaacatctgtactcactcac agtgttgtaagtaagaccagcatggtctctgtgccttcctcagctcctgctgtttcagcc aaagtattctctctttttagaagctcttctttggattcttctacacatccttctccaccc ccacctcctcctcctccaccacctcctccaccaccattaccaccaccacctattttaccc aagccagccatttatcccaaaaagaaaccacagattaaggctccagcagcaacagctcct acagtggtacctccggtcacaagtgttccaacactagagtccattgctgtattaaaggat catgtggtacctgtcacaaaaacatacaccccaacaccacctcctgtaccacccaaacca tcctccattccagcagggcttgtcttcagtcataggccccctgaagtaactaagcctcca attgctcctaaaccagcagttcctccgctcccaatatctgttcataagccagcagaaata cagcccaaaccagtaagcttgtcattgacttcaagtatgactctgaatttggtatccaca gctgaatacaaaataccatctcccacttcccctttgtctccacactctaacaaatcttca ccaaggttggcaaaaccctcacaggaaacctatgttgtcatcacattgccatctgagcct gggactcccactgaagctataactagccaggctgttaccagctggcctttagaagaacct tctaaagaacagattccccaacctatgcaaccagtttttactacatccatgaaaacgatg gatattcaaagtatggcaggtcagagtatgtatatttcaggtgcgctgcaagctattcct gtgacaacacaatcaactttcgaaaaaatacctacttcaaaatcagtagtagcaacaaca gacattaccaagaccacagtgtctgtggttaagggtccagtgcctggttatggtttaggt agtgttgctattactatacctccagagccactacatattgtagatcaacccagatataga gagaatggaagattccatcctttgggcgatgtcatagatcttcgcacattaactaagatg gacattgaaatgagggacagctgtatggatctctctgctgtttccatggatgtaagaagg caaatgccagcaagtgacacaagtggacggccagtaagtactgtccagccatccataata aatcttagcactgcatgtgttgctgatacttctctgcctgtagtcactgagacagtaact gtaatgacctgcactgccactgtgagctacaccaccagcacagacagccttgtggatctg ggacatgcgatgacaacaccgcttcagctaacaacatccaaacattttgagcctgcatac agagtaacaggcagccaggccttctctgtaggtagagatgaagtgccaataaatttatca ctaggtacttcagcacaggcagtgacatgggctgctacaaagcctgttactgtgccacct gttggtgttacaaatggttggactgatctctccacttctcaggagccagcagagagtgga gcagttgaccttagcactacaaaatcccacagaacagtagtaacaatggatgacacatct tcaggtatcgtaacaacagtaattgaagatgatgaaaagcctgtagatctgactgcaggg agaagagctgtctgctgtgatatggtttataaattgccatttggtaggagctgtacagca cagcagccttctactacacttcctgaagatcgctttggctacagagatgaccattatcag tatgaccgttcagggtcatatggctatcgaggaattggaggtatgaaaccatctatgtct gacacaaatttatcagaagctggactatttgcatacagaagcaaaaatagctttgattat cgagttggggcaactgatacagcagtagatcttacttctggaagagtaactacaggtgag gttatggattactcaagcaagactacaggtccatatccagagactcggcagatttctggc cttgggctcagtacgccacagtattcccaagcaagaatggtgtcatctgtgggttcccag tttggcgttggaagtgttttaaggtcatccaatggtgttgtttattcttcagtagcaact ccaatcccatccacatttgccatcaccacacaacctggttctattttcagtacaagtgtc agagatttacctactctccaaacaattgactcagtgccctctttatcaactttgcaacag actcaaccacttccaagatcatatagtttcttgacaactgtggcagctgaaaaagacaaa gcaattactgccgttggtatggagacagggttgccacctcattctatagaaactattacc actgagccaaccagcttgatacctgctttaactacggcatctgaagtttatacagatgta attgatgatgaggttgcccttctcattgcccctgaagaaggcaaacagcagcagcttgat ttggagcgggaacttcttgagcttgagaaaattaagcagcagcgctttgcagaagagctg gaatgggaacgtcaggaaattcaaagatttagggaacaagaaaagtttatggtgcaaaaa aagcttgaggagttgcaatccatgaaacatcatctcttatttcagcaggaggaggaacga caagctcagtttatgatgagacaagagacattagcacagcagcaattgcagcttgaacaa ttccaacaactccaacaacagctccaccaacagctagaggagcaaaaacttcgtcaaata tatcagtatggttatgacccttcaggaactggctcaccacaaactaccacagatcaaaca cttttggagggacagtatgcaagcacagaaaatggccaattttggcctactgatgacaca accactacagcttcaggagttctgggtattgaaattccacaaagtcaaacatggtataca gttcagtctgatggcattacccaatatatacccaggtctggtatcctaagctcagtttca gaaatgtctcttaaggatattgatgttagagaggagaaacaattgaaaaagagaagttct atgccaaagttacgtggtccttatgaagagtttgaggagaccctggaagaagagccccgg tgtttcaaaaaaatagtggacagtggagtgcaaactgatgatgaagatggagcagacaga ggttacaccaacaggaggcggagatctaagaagagtgttgatacaagtgttcagacagat gacgaagatcaggatgaatgggatctttccagcagatccagaagaaagcctcgtgtaggg aaatacagcgagagcaccactgaggcagacaaagctaaaccattctccaaggtatctagt attgcagttcagacagtggcagagatttctgtgcaaacagaacctgtaggaacaataaga acaccttcaatcagggcccgatgggatgctaaggttgaaatcataaagcatatttcagct ccagaaaagacatataaaggagaaagtctgggatgtcaaacagagacagcatcagacact caaagcccccagtatctgtcagcttcatctcctcagaaagataaaaaacgtcctacacca ctagagataggatactcatcccacctgcgtccagactccacattacaggtagttccttcc cctcccaaatcccccaaagttctctattcacccatttcacccgtttcaccaagcaaagtt atagagtcagcatttgtaccttatgagaaacccatgactgatgacatcagccctcagaag atgctgcatgctgacatggccaaggttcctccatcaagcccaaaggcagcaaagatgatg caacgctctatgtctgatcctaaacccctgagtcccacagcagaagacagttccagagct cagtttcagtacactgagggttttatgtcaaaaggttcttcaagcatgactccatccagc actcaaaagaaggtgaagaggactcttcccaatccacctccagaggaagcaacagcagga actcagtccccatacacttctgtgggatcagtttcacggagaaggatttgtaggaccacc actatggccagagccaaaattcttcaggatatagacagggaattggatctggtcgaacgt gaatcagccaagcttaggaagaagcaagcagagctagatgaggaggaaaaagaaatagat gccaagttgagatacttggaaatgggcattaataggaggaaagaagccctactaaaagaa agagaaaagagagagcgtgcctatctccaaggagtagcagaagaacgtgattatatgtca gacagtgaagttaataataccagatcaaccagaatagaaactcaacatggcttggaaaga ccacgtactgcaccccagacagaatttaaccaatttataccaccacaaacccagccagaa acacagtttgcccctgctacaagcccatatgctcaatatcagtattcatctcctgccctt ccaactcaagcaccaactcaattcacacagcagtcacattaccaacaacaacagcctttg tatcaccagcaggtttcaccctatcagacccagacagcattccagacaggagctaccatg tcctttaccccacaggctcaacctccaccatctcaacagccatcatatcagctcccatca cagatgatggtgatacagccaaagccaagacagaccacattatatttggagcctaagata acaacaaactatgatgtaattcgcaatcagcctctcatgatagcaccagtttcaactgac aatacttatgcagtttcccagctgggcagtaaatactccaccttggacttaaggatagga ctagacgagagaaacagcatagccagcagccctatatcaagcatatctgctgattcattc tatgcagatatagaccaccaccatacaccccgaaattatgtgctgattgatgatatagga gaacttactaaaggaacaggaactcttggttccagttttagcctccatgagaaagatctg accaaaacagatcgacttcttcgcacaactgaggccaggagagcacaagaagtgtcagac ttcctagcaccactacagacttcctctaggttacattcctatgttaaagctgatgaagac ccaatggaggacccttatgagctcaaacttctgaaacaccagataaagcaagagttccgt agaggtgcagaaagtctcgatcatctggctggcctgtcacaatattaccacggagagggc agctacaggcattttccaaaatctgagaaatatagcataggtaggcttactcttgagaaa caggctgctaagcagctcccagcagccctcctttaccagaagcagtcaaaacacaagaaa gccttgatagaccccaaactaacaaagttttcacctatccaagaaagcagagaccttgag cctgactattcaagctatatgacttctagcacttcaacacttgggggaattactactagg gcaaggcttcttcaggatgatatcacttatggccttagaaaaaacatcagtgaccaacag aagtacatggggccaccactgacgtcatccattggagcaggccttgggactgcactaggt ccaacaatgagagccacactacaagacgaagcagacaagtcttatagcagtggtagtaga tctaggccctcatctaggccctcctcagtgtatgggctcgatttgtcactgaaaagggat tcttccagttcttctttaagactgaaagcccaagaagctgaacctttagatgtttccttt agccatgcagcaccttctggaagaactaaacccaccagtctacctattagccaaagcagg ggaaggatcccaatagtagcgcagaactcagaggaggagagcccactaagtcctgttgga cagccaatgggaatggcaagagcggcagctggacccttgccaccaatatctgcagatacc agggaccagtttggatcgagccattcattacctgaggtccagcagcatatgagggaggag tcacggactcgaggctatgatcgagatatagccttcatcatggatgacttccagcatgcc atgtcagacagtgaagcctatcatctccgtcgggaagaaacagattggtttgacaagccc agagagcctcgtttggagaatggacacatccttgacagaaggctgccagagaagttgtca cactctcgaccactaagtcaacaccaagatcaaataaatgggaagcccctgcagtacatt ttccctcatacaaggctcaaactactgagagacccaaaggatcacacagtttcaggcaat ggactgggaatccgagttgtaggtgggaaagaaattccaggaagcagtggggaaattgga gcttacattgccaagatcttgcctgggggcaatgcagagcagacagggaagctcatagaa ggaatgcaggtgctggaatggaatggcatccccttgaccgggaaaacttatgaagaggtc cagagcattattattcaacagagtggggaagcagaaatatgtgtaagactggacctgaac atgctctcggactctgagaatccccagcacctggaactgcatgagccagtaagggcagta gataaagcgaagtccccaggggttgatcccaagcagctggctgcagagctccaaaaggtt tctctacagcagtcgcctctggttgcttcttcaggagtggaaaagggatctcacgtccac tctggcaccgcttctgccacctccagcgctgttcctagccctggtcagccaggttctccc tcagtgagcaaaaagcggcacagcagcaagcccacggaaactacaaagcctgcttcccat ccaatcactggagaaatacagcttcaaatcagctatgacaaacaccttggcaaccttatc atccacatccttcaggcaagaaaccttgctcccagagacaacaacggctattcagacccc tttgttaaagtttatcttcttccagggagaggacaagtcatggttgtccaaaacgccagt gctgagtacaagcggagaactaagtacatacagaaaagcctgaatcctgagtggaatcag acagtcatttacaaaaatatctccatggagcagctgaaaaagaaaacactggaagtgact gtttgggattatgatagattctcctcaaatgacttcctcggtgaagtattgatcgagtta tccagcatctctcagcttgacaacactcctcggtggtatcctcttaaagaacagagtgaa aacatagatcatgggaaatctcattctgaaaagagtagccagcaatctccaaaaccatct gtcatcaagagcagaagtcatggaatattcccggacccctccaaggacatgcaggtgccc accattgagaaatcccacagcagcccagggagctccaaatcttcttctgaaggacatctc cgctctcacggtccatctcgcagccaaagcaaaaccagcgtcactcaaactcaccttgaa gatgctggggcagccatcgccgctgctgaagcagctgtgcaacagcttcgccttcaacca acagcacataaaagcggtcagtctaatcatgccaggaagcagcacagacacagcatagca ggagtcctccctattcaaagaactcagtctgacaatctgcctccaccagccaatgacaac aaagaccaaagccaactagccctcaggaaggtgatgtctgatggaccagtcaagcctgaa ggagcaaggtctactaatcaccgacctgcagaaagttctgtctccactggctcatcagcc agtagttttggcagtggatacagcatggatagcgaaggcagcagcagtgccactggagag aataatttatttcccatcccaagaatagggaagatgagccagaatggacaagaacctgta aagcagtcgggagtaggagtaaccgattcagaaggtaaaacacaggttatgggtgaaatc aagattgcattaaagaaggaaatgaagacagatggagaacaactgatagtggaaatcctt cagtgcagaaatatcacatacaaatttaaatctccagatcatcttccagacctgtacgtg aagctgtatgttgtcaatatctctacccaaaagagagtaattaagaagaaaaccagggta tgcaggcatgaccgagagccttcattcaatgaaacatttagatttagcttgagtcctgct gggcattctcttcagattcttcttgtctccaatggagggaagtttatgaaaaagacactg attggggaagcttatatctggcttgacaaagtggatctaaggaaaagaatagtaaactgg cacaaactgttggtcagctccacgcaaacacactga

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