Pongo abelii (Sumatran orangutan): 100173631
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Entry
100173631 CDS
T01416
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00020
Citrate cycle (TCA cycle)
pon00190
Oxidative phosphorylation
pon01100
Metabolic pathways
pon01200
Carbon metabolism
pon04714
Thermogenesis
pon04932
Non-alcoholic fatty liver disease
pon05010
Alzheimer disease
pon05012
Parkinson disease
pon05014
Amyotrophic lateral sclerosis
pon05016
Huntington disease
pon05020
Prion disease
pon05022
Pathways of neurodegeneration - multiple diseases
pon05208
Chemical carcinogenesis - reactive oxygen species
pon05415
Diabetic cardiomyopathy
Module
pon_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pon_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
pon_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100173631 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
100173631 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
100173631 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100173631 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
100173631 (SDHA)
05012 Parkinson disease
100173631 (SDHA)
05014 Amyotrophic lateral sclerosis
100173631 (SDHA)
05016 Huntington disease
100173631 (SDHA)
05020 Prion disease
100173631 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
100173631 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100173631 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100173631 (SDHA)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
100173631 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
100173631
NCBI-ProteinID:
NP_001126633
UniProt:
Q5R616
A0A2J8XSC5
LinkDB
All DBs
Position
5:110430..140875
Genome browser
AA seq
664 aa
AA seq
DB search
MSGVRGLSRLLSARRLALAKAWPTVLQTGARGFHFTVDGNKRASAKVSDSISAQYPVVDH
EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR
WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF
GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIE
DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI
YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE
KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ
VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK
VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS
KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR
IDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVSTGKVTLEYRPVIDKTLNEADCATVPPA
IRSY
NT seq
1995 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggggtcaggggcctgtcgcggctgctgagcgctcggcgcctggcgctggccaag
gcgtggccaacagtgttgcaaacaggagcccgaggttttcacttcactgttgatgggaac
aagagggcatccgctaaagtttcagattccatttctgctcagtatccagtagtggatcat
gaatttgatgcagtggtggtaggcgctggaggggcaggcttgcgagctgcatttggcctt
tccgaggcagggtttaatacagcatgtgttaccaagctgtttcctaccaggtcacacact
gttgcagcgcagggaggaatcaatgctgctctggggaacatggaggaggacaactggagg
tggcatttctacgacaccgtgaagggctccgactggctgggggaccaggatgccatccac
tacatgacggagcaggcccctgctgccgtggtcgagctagaaaattatggcatgccgttt
agcagaactgaagatgggaagatttatcagcgtgcatttggtggacagagcctcaagttt
ggaaagggcgggcaggcccatcggtgctgctgtgtggctgatcggactggccactcacta
ttgcacaccttatatggaaggtctctgcgatatgataccagctattttgtggagtatttt
gccttggatctcctgatggagaatggggagtgccgtggtgtcatcgcactgtgcatagag
gacgggtccatccatcgcataagagcaaagaacactgttgttgccacaggaggctacggg
cgcacctacttcagctgcacgtctgcccacaccagcactggcgatggcacggccatgatc
accagggcaggcctcccttgccaggacctagagtttgttcagttccaccccacaggcata
tacggtgctggttgtctcattacggaaggatgtcgtggagagggaggcattctcattaac
agtcaaggtgaaaggtttatggagcgatacgcccctgtcgcgaaggacctggcgtctaga
gatgtggtgtctcgttcgatgactctggagatccgagaaggaagaggctgtggccctgag
aaagatcatgtctacctgcagctgcaccacctacctccagagcagctggccacacgcctg
cctggcatttcagagacagccatgatcttcgctggcgtggatgtcacgaaggagccgatc
ccggtcctccccaccgtgcattataacatgggcggcattcccaccaactacaaggggcag
gtcctgaggcacgtgaatggccaggatcagattgtgcccggcctgtacgcctgtggggag
gccgcctgtgcctcggtacatggtgccaaccgcctcggggcaaactcgctcttggacctg
gttgtctttggtcgggcatgtgccctgagcattgaagagtcatgcagacctggagataaa
gtccctccaattaaaccaaacgctggggaagaatctgtcatgaatcttgacaaattgaga
tttgctgatggaagcataagaacatcggaactgcgactcagcatgcagaagtcaatgcaa
aatcatgctgccgtgttccgtgtgggaagcgtgttgcaggaaggttgtgggaaaatcagc
aagctctatggagacctaaagcacctgaagacgttcgaccggggaatggtctggaacacg
gacctggtggagaccctggagctgcagaacctgatgctgtgtgcgctgcagaccatctac
ggagcagaggcacggaaggagtcacggggtgcgcacgccagggaagactacaaggtgcgg
attgatgagtacgattactccaagcccatccaggggcaacagaagaagccctttgaggag
cactggaggaagcacaccctgtcctatgtggacgtcagcactgggaaggtcaccctggaa
tatagacccgtaatcgacaaaactttgaacgaggctgactgtgccaccgtccccccagcc
attcgctcctactga
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