Pongo abelii (Sumatran orangutan): 100441867
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Entry
100441867 CDS
T01416
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00020
Citrate cycle (TCA cycle)
pon00480
Glutathione metabolism
pon01100
Metabolic pathways
pon01200
Carbon metabolism
pon01210
2-Oxocarboxylic acid metabolism
pon01230
Biosynthesis of amino acids
pon04146
Peroxisome
pon05230
Central carbon metabolism in cancer
Module
pon_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pon_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100441867 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100441867 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100441867 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100441867 (IDH2)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
100441867 (IDH2)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
100441867
NCBI-ProteinID:
XP_002825863
UniProt:
A0A2J8VX59
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Position
15:complement(70408539..70426964)
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AA seq
452 aa
AA seq
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MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADRRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGVGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgggtcgtgcgctcgctctgcagagcctcaggctcgcggccggcc
tgggcgccggcggccctgacagcccccacctcgcaagagcagccgcggcgccactatgcc
gacagaaggatcaaggtggcgaagcccgtggtggagatggatggtgatgagatgacccgt
atcatctggcagttcatcaaggagaagctcatcctgccccacgtggacatccagctaaag
tattttgacctcgggctcccaaaccgtgaccagaccgatgaccaggtcaccattgattct
gcactggccacccagaagtacagtgtggctgtcaagtgtgccaccatcacccctgatgag
gcccgtgtggaagagttcaagctgaagaagatgtggaaaagtcccaatggaactatccgg
aacatcctgggggggactgtcttccgggagcccatcatctgcaaaaacatcccacgccta
gtccctggctggaccaagcccatcaccataggcaggcacgcccatggcgaccagtacaag
gccacagactttgtggcagaccgggccggcacgttcaaaatggtcttcaccccaaaagac
ggcagcggtgtgaaggagtgggaagtgtacaacttccccgcaggcggcgtgggcgtgggc
atgtacaacaccgacgagtccatctcgggttttgcgcacagctgcttccagtatgccatc
cagaagaaatggccactgtacatgagcaccaagaacaccatactgaaagcctacgatggg
cgtttcaaggacatcttccaggagatctttgacaagcactataagaccgacttcgacaag
aataagatctggtatgagcaccggctcattgatgacatggtggctcaggtcctgaagtct
tcgggcggctttgtgtgggcctgcaagaactatgacggagatgtgcagtcagacatcctg
gcccagggctttggctcccttggcctgatgacgtccgtcctggtctgccctgatgggaag
acaattgaggctgaggccgctcatgggaccgtcacccgccactatcgggagcaccagaag
ggccggcccaccagcaccaaccccatcgccagcatctttgcctggacacgcggcctggag
caccgggggaagctggatgggaaccaagacctcatcaggtttgcccagacgctggagaaa
gtgtgcgtggaaacggtggagagtggagccatgaccaaggacctggcgggctgcattcac
ggcctcagcaatgtgaagctgaacgagcacttcctgaacaccacggacttcctcgacacc
atcaagagcaacctggacagagccctgggcaggcagtag
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