Pongo abelii (Sumatran orangutan): 100451393 Help Entry 100451393         CDS       T01416                                  Symbol OBSCN Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pon00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100451393 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pon01001]     100451393 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pon04131]     100451393 (OBSCN) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100451393 (OBSCN) Protein kinases [BR:pon01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    100451393 (OBSCN) Membrane trafficking [BR:pon04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     100451393 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 C1-set C2-set_2 Izumo-Ig fn3 RhoGEF PH ABC1 IQ Pkinase_fungal Motif Other DBs NCBI-GeneID:  100451393 NCBI-ProteinID:  XP_024088469 Ensembl:  ENSPPYG00000000139 LinkDB All DBs Position 1:complement(21191468..21362353) Genome browser AA seq 8916 aa AA seqDB search MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIR VREGSEATFRCRVGGSPKPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPP STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILF CKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVSQPS TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQG NLLRKLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS QCCLEDVGQVAFMAGDCRTSTQFCVSAPRKPPLQPPVDPVVKARTESSVILSWSPPPHGE RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVVEEGNFQFRVSALNSFGQSPY LEFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEMH CDRTRHTLTIREVPASLHGAQLKFVANGVESSIRMEVRAAPGLTANKPPAAAAREVLARL HEEAQLLAELSDQAAAVTWLKDGHTLPPGPKYEVQASAGQQVLLVRDVARDDAGLYECVS CGGRIAYRLSVQGLACFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHS GERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKAVFTKEQPTRREV QAEAGASATLSCEVAQDQMEVTWYKDGKKLNSSSKVRVEAVGCTRKLVVQQAGQADAGEY SCEARGQRVSFRLDVAEPKVVFAKEQLAHRKLQAEAGASATLSCEVAQAQTEVTWYKDGK KLSSSSKVCMEATGCTRRLVVQQAGQADAGEYCCEAGGQRLSFHLDVKEPKVVFAKDQVA HSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLQVHVEAKGCRRRLVVQQAGKTD AGDYSCEARGQRVSFRLHITEPKGVFAKEQSVHNEVKAEAGTSAMLSCEVAQAQTEVTWY KDGKKLSSSSKVGMEVKGCTRRLVVLQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAK EQSVHNEVKAEAGTSAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVVQQV GKTDAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTE VMWYKDGKKLSSSSKVRVEAAGCMRQLVVQQAGQADAGEYTCEAGGQWLSFHLDVSEPKA VFAKEQPAHREVQAEAGTIATLSCEVAQAQTEVMWHKDGKKLSSSSKVRMEAVGCTRRLV VQQACQADGGEYSCEAGGQRLSFNLHVAEPKAVFAKEQPVHREVQAQAGASATLSCEVAQ AQTEVMWSKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGSQRLSFHLHVA EPKAVFAKEQPAHREVQAEAGASTTLSCEVAQAQTEVTWYKDGKKLSSSSKVHVEAAGCT RRLVVQQAGQADAGEYSCEAGGQQLSFRLHVAEPKAVFAKEQPASREVQAEAGTSATLSC EVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCEAGGQRLSFR LHVAEPKVVFAKEQPAHRELQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEA VGCTRRLVVQQAGQAEAGEYSCEAGGQRLSFRLQVAEPKAVFAKEQPAHREVQAEAGTST TLSCEVAQAQTEVMWYKDGKKLSSSSKMRVEAVGCTRRLVVQEAGQADAGEYSCEAGGQR LSFHLHVADPKVVFAKEQPACREVQAEAGASATLSCEVAQGQMEVTWYKDGKKLSSSSKV RMEANGCTRRLVVQQAGQADAGEYTCEAGGQRLSFHLHVAEPEPQISERPCRREPLVVKE HEDIILTATLATPSVATVTWLKDGVEIRHSKRHETASQGDTHTLTVHGAQVLDSAIYSCR VGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVGK RFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDRTSAQLTVSVPQVVKFMSGLSAVVAEE GGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISGLVLEDAGQITVEA EGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKN VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQG TATMEVQLSHADVEGSWTRDGLRLQQGPTCHLAVRGPVHTLTLSGLRPEDGGLMVFKAEG VHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMA IAAQGACRSLTIYRCEFVDQGVYVCDAHDAQSSASVKVQGRNIQIVRPLEDVEVMEKDGA TFSCEVSHDEVPGQWFREGSKLRPTDNVRIRQEGRTYTLIYRRVLAEDAGEIQFVAENAE SRAQLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYELV SDGLYRKLIISDVQAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWF ECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTIGKSRS SARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSL EGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFS CELSHEDEEVEWSLNEMPLYNDSFHEISHKGRRHTLVLKSVRRADAGIVRASSLKVSTYA RLEVRVKPVVFLKALDDLSAEEHGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTA GTRGLVVHDLTSEDAGLYTCHVGSEETRARVSVHDLHVGITKRLKTMEVLEGESCSFECV LSHESTSDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKA SLIVRERPAAIIKPLEDQRVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEG TMAMLVIRGASLKDAGEYTCEVEASKSTASLRVEEKANCFTEELTNLQVEEKGTAVFMCK TERPAATVSWRKGLLELRASRKHQPSQEGLVLRLTISALEKADSDTYTCDIGQAQSQAQL LVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIEAQPG GYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCE TSACDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIV RVHARPVRFQEALKDLDVPEGGAATLRCVLSSVAAPVKWCCGNNVLRPGDKYSLRQEGAV LELVVRNLRPQDSGQYSCSFGDQTTSATLTVTALPAQFIRKLRNKEATEGATATLRCELS KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQICGLAMVDAGEYSCVCGEERTSASLTIR AMPAHFIGRLRHQESTEGATATLRCELSKAAPVEWRKGHESLRDGDRHSLRQDGAVCELQ ISGLAVADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP VEWRKGPKNLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPA RFIEDVKNQEAREGATVMLQCELNSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGL AMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATATLRCELSKMAPVEWW KGHETLRDGDRHSLRQDGAKCELQIRGLVAEDAGEYLCMCGKERTSATLTVRALPSKFIE GLRNEEATEGVTATLQCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVD AGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATVVLQCELSKAAPVEWRKGSE TLRGGDRYSLRQDGTRCELQIRGLSVADTGEYSCVCGQERTSATLTVRALPARFTQDLKT KEASEGATATLQCELSKVAPVEWKKGPETLRDGGRYSLKQDGTRCELQIHDLSVADAGEY SCTCGQERTSATLTVRALPAKFTAGLRNEEATEGATATLQCELSKAAPVEWRKGLEALRD GDKYSLRQDGAVCALQIHGLAVADTGVYSCVCGQERTSATLTVRALPARFIEDMRSQKAT EGATVTLQCKLRKAAPVEWRKGPNTLKDGDRYSLKQDGTRCELQIRGLIIADAGEYSCIC EQERTSAMLTVRALPARFIEDVRNHEATEGATAVLQCELSKAAPVEWRKGSETLRDGDRY SLRQDGTRCELQIHGLAMEDTGEYLCVCGQERTSATLTVRALPARFIDNMTNQEAREGAT ATLQCELSKAAPVEWRKGPETLQDGDRHSLRQDGTRCELQIRGLAVADAGEYSCVCGQER TSAMLTIRALPAKFTKGLTNEEATEGATAVLQCELSKAAPVEWRKGPETLRGGDRYNLRQ DGTRCELQIHGLSVADTGEYSCVCGQEKTSATLIVKAPHPVFREPLQSLQAEEGSTATLQ CELSQPTATVVWSKGGLQLQANGRREPRLQGCTAELVLRGLQREDTGEYTCTCGSQATSA TLTVTAAPVWFLRELQPQEVDEGGTAHLRCELSRAGASVEWRKGSLQLFPCAKYQMVQDG AAAELLVCGVEQEDEGDYTCDTGHTQSMASLSVCVPRPKFKTRLQSLEQETGDIARLCCQ LSDAESGAMVQWLKEGVELHAGPKYEIRSQGATRELLIHQLEAKDTGEYACVTGGQKTAA SLRVTEPEVTIVQGLVDAEVPADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVR DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTIRAPEVTILEPLQDVQLSEGQDASFQ CRLSRASGQEARWALGGVPLQANEMNDIAVEQGALHLLTLHKVTLEDAGTVSFHVGTCSS EAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVRTSENAEVVF FENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILKPLKNTAVRAGAQAH FTCTLSEAVPVGEASWYFNGAAVQPDDSDWTVTADGSHHALLLHSAQPHHAGEVTFACRD AVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWR LCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAP ESRQVAAGEDVCLELEVAAEAGEVIWHKGTERIQPSGRFEVVSQGRQQMLVIRGFTAEDQ GEYHCGLAQGSTCPAAATFQVALSPASVDEAPPQPSLPPEAAQEGDLHLLWEALARKRRM SREPTLDSISELPEEDGRSQRLPQEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDES RAGTPSLVTYLKKAGRPGTSSLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGD PSMDKAAVKIQAAFKGYKVRKEMKQQEGPVFSHTFGDTEAQVGDALRLECVVASKADVRA RWLKDGVELTDGRHHHIDQLGDGTCSLLITGLGRADAGCYTCQVSNKFGQVAHSACVVVS GTESEAESSSGGELDDAFRRAARRLHRLFRTKSSTEVSDEELFLSAEEGPAEPEEPVDWQ TYREDEHFICICFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMRISKETPAP VVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPVPSVRWFKDGKLLEED DHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADA TESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPA PRLYWFKDGQPLTASAHIRMTDKKTLHTLEIISVIREDSGQYAAYISNAMGAAYSSARLL VRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPAPTVHWLREEA ERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGL PKVEEQEKVKEALISTFLQGTTQAVSAQGLETASFADLGGQRKGEPLAAKEALGHLSLAE VGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSDEDSKTPSASPRHGRSRPSSSIQESS SESEDGDARGEIFDIYVVTADYLPLGAEQDAIALREGQYVEVLDAAHPLRWLVRTKPTKS SPSRQGWVSPAYLDRKLKLSPEWGAAEAPEFPGEAVSEDEYKSRLSSVIQELLSSEQAFV EELQFLQSHHLQHLERCPHVPAAVAGQKAVIFRNVRDIGRFHSSFLQELQQCDTDDDVAM CFIKNQAAFEQYLEFLVGRVQAESVVVSTAVQEFYKKYAEEALLAGDPSQPLPPPLQHYL EQPVERVQCYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGT LEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTFSYVFRN MMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEICGIQQRLALP VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKPVQVDPHHILIEDPDGS CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTC TIEGAPYPQIRWFKDGALLTPGSKFQTLSEPRSGLLVLVIRAAGEEDLGLYECELVNRLG SARATAELHMQSPTLQAREQYHREQLAAAVEDTTLERADQEITSILKRLLGPKAPGPSTG DLTGPDPCPGGAPALQETGSQPPVTGTLEAPAVPPRVPQPLLHEGPEQEPEAIARAQEWT VPIRMEGAAWPGAGTGELLWDVHSHVVTETTQRTYTYQAIDKHTARPPSMQVTIEDVQVQ TGGTAQFEAIIEGDPQPSVTWYKDSIQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTC LAQNAGGQVLCKAELLVLGGDNEPDSEKQSPRRKLHSFYEVKEEIGRGVFGFVKRVQHKG NKIFCAAKFIPLRSRTRAQAYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEEL LDRLFRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPARENIKICDFG FAQNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFAGESDR ATLLNILEGRVSWSSPMAAHLSEDAKDFIKATLQKAPQARPSAAQCLSHPWFLKSMPAEE AHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLRGPPDSPSLGVARHLCRDTGGS SSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEEAEASERSTEAPALP ASPEGAGPPAAQGCVPRHSVIRSLFYQQAGESPERGALAPGSRRHPARRRHLLKGGYIAG ALPGLREPLMEHRVLEEEAATEEQTTLLAKAPSFETALRLPASGTHWAPGRSRSLEHDPP STPRPSLEACCEAQRLPSAPSRGAPIRDMGHPQGSKQLPSTGGHPGTAQPERPSPDSPWG QPAPFSHPKQGSAPQEGCSPHPAVAPCLPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAK ASPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSRVGSSQVGTEPGPSLDAEGW SQEAEDLSDSTPTLQRPQEQATMRKFSLGCRGGYAGVAGYGTFAFGGDAGGMLGQGPMWA RIAWAVSQSEEEEQEEARAESQSEEQQEAARAESPLPQVSARPVPEVGRAPSRTSPEPTP WEDVGQVSLVPIQDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRKVPK PAQLEPPSPMAEEELAEFPEPMWPWPGELGPHAGLEITEEPEDVDALLAEAAVGRKRKWS SPSRSLFHFPGRHLPLDEPAELGLRERVKASVEHISRILKGRPEGLEKEGPPRKKPGLAS FRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVL ISATLKNFQLLTILVVAAEDLGVYTCSVSNALGTATTTGVLRKAERPSSSPCPDIGEVYA DGVLLVWKPVESYGPVTYIVQCSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVS KAGMGPYSSPSEQVLLGGPSHLASEEENQGRSAQPLPSTKTFAFQTQIRRGRFSVVRQCW EKASGRALAAKIIPYRPKDKTAVLREYEALKGLHHPHLAQLHAAYLSPWHLVLILELCSG PELLPCLAERASYSESEVKDYLWQMLSATQYLHTQHILHLDLRSENMIITEYNLLKVVDL GNAQSLSQEKVLPSEKFKDYLETMELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGA RDLQRGLRKGLVQLSRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGPACS RPAPVTFPTARLRVFVRNREKRRALLYKRHNLAQVR NT seq 26751 nt NT seq  +upstreamnt  +downstreamnt atggatcagccacagttcagcggggcgccccgctttctcacccggcccaaggccttcgtg gtgtcggtgggcaaggacgccaccctcagctgccagatcgtgggtaatcccacgccacag gtgagctgggagaaggaccagcagccggtggcggcgggcgcgcgcttccgtctggcccag gacggcgacctctaccgcctcactatcctggacctggcgctgggcgacagtgggcaatac gtgtgccgcgcgcgcaatgccataggcgaggccttcgctgccgtgggcctgcaggtggac gccgaggccgcgtgcgccgagcaggcgccgcacttcctgctgcggcccacgtccatccgc gtgcgcgagggctcagaggccaccttccgttgccgcgtgggtggctccccgaagccggca gtgagctggtccaaggacgggcggcgcctgggtgagcccgacggcccccgcgtgcgcgtg gaggagctcggcgaggcgagtgcgttgcgcattcgggcggcgcggccgcgcgacggcggc acttacgaggtccgcgccgagaacccgctgggcgccgccagcgccgccgcagcgctcgtg gtggactcggacgccgcggacacggccagccggcccgggacctccacggccgcgctcctg gcgcacctgcagcggcggcgcgaggccatgcgcgccgagggcgccccagcctcaccgccc agcaccggcacgcgcacctgcacggtgaccgaagggaagcacgcgcgcctcagctgctac gtgaccggcgagcccaagcccgagacggtgtggaagaaggacggccagctggtgaccgag ggccggcggcacgtggtgtacgaggacgcgcaggagaacttcgtgctcaagatcctcttc tgcaagcagtcggaccgcggcctctacacctgcacggcgtccaacctcgtgggccagacc tacagctccgtgctggtcgtagtgcgcgagcccgcggttcccttcaaaaagcggctgcaa gatctggaggtgcgggagaaggagtcggccacattcctgtgcgaggtgtcccagccgtcc actgaggccgcgtggttcaaggaggagacgcggttgtgggcgagcgccaagtacggcatc gaggaggagggcaccgagcgccgcctgaccgtgcgcaatgtctcggccgacgacgacgcg gtgtacatctgcgagacgccagagggcagccgcacggtggcggagctcgcagtccaagga aacctcctccgaaagctccctcggaagacggcggtgcgcgtgggcgacacggccatgttt tgcgtggagctggcggtcccggtgggccccgtccactggctgcggaaccaggaggaggtg gtggccgggggccgcgtggccatctccgcggagggcacgcgccacacactgaccatctcc cagtgctgcctggaggatgtgggccaggttgcctttatggctggcgactgccggacatcc acccagttctgcgtgtcggcccccaggaagcctcccctgcaaccccctgtggatcctgtg gtaaaggccaggacggagagttctgtgatcctcagctggtccccaccaccccatggggaa cgccctgtcactatcgacggctacctggtagagaagaagaagcttggcacctacacctgg atcaggtgccacgaggctgaatgggtggctacacctgagctgaccgtggctgatgtggtg gaggaggggaacttccagttccgagtgtcagctctcaacagctttggtcagagtccctac cttgagttcccggggactgtccacctggcccccaagctggccgtgaggacaccgctgaag gcggtgcaggcagtagagggtggcgaggtcactttctccgtggacctcacggtggcctca gcgggtgagtggttcctggatgggcaggccctgaaggccagcagtgtgtatgagatgcac tgtgatcgcacccggcacacgctcaccatccgggaggtgcccgccagcctgcatggggcg cagctgaagttcgtggccaacggcgttgagagcagcatccggatggaggtccgggcggcc ccagggctgactgccaacaagccgccagccgcagctgcccgggaggtgctggctcggctg cacgaggaggcgcagctgctggctgagctgtcagatcaggctgcggctgtgacgtggctg aaggatggtcacacactgcccccaggccccaagtatgaggtgcaggcatcagccgggcag caggtgctccttgtgcgagatgtggcccgggacgatgcaggcctctacgagtgcgtcagc tgcgggggccgcatcgcctaccggctgtccgtgcaaggcctcgcgtgctttctgcacaag gacatggcgggcagctgtgtggatgctgtggctgggggcccggcgcagtttgagtgtgag acctccgaagcccatgtccacgtgcactggtacaaggatggcatggagctgggccactct ggtgagcgcttcttgcaggaggatgtggggacgcggcaccggctggtggcagccacagtc accaggcaggatgagggcacctactcctgccgcgtgggcgaggactctgtggacttccgg ctccgcgtctctgagcccaaggcggtgtttaccaaggagcagccgacacgcagggaggtg caggctgaggcgggggccagcgccacgctgagctgtgaggtggcccaggaccagatggag gtgacgtggtacaaggacgggaagaagctgaactccagctcgaaagtgcgcgtggaagcc gtgggctgtacgcggaagctggtggtgcagcaggcgggccaggcagacgccggagagtac agctgtgaggccaggggacagagggtctccttccgcctggatgttgcagagcccaaggtg gtgtttgccaaggagcagctggcgcacaggaagctgcaggcagaggcaggagccagtgct acactgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaaggatgggaag aagctgagctccagctcaaaagtgtgcatggaggccacaggctgcacacggaggctggtt gtgcagcaggcgggccaggcggatgccggggagtactgctgtgaggctgggggccagcgg ctctccttccatctggacgtcaaagagcccaaggtggtgtttgccaaggaccaagtggca cacagtgaggtgcaggctgaggcaggggccagtgccactctgagctgtgaggtggcccag gcccagacggaggtgatgtggtacaaagatgggaagaagctgagttccagcttgcaagtg catgtggaggccaagggctgcagacggaggctggtggtgcagcaggcgggcaagacagat gccggggactacagctgtgaggccaggggccagagggtctccttccgcctgcacatcaca gagcccaagggggtgtttgcaaaggagcagtcagtgcataatgaggtgaaggctgaggcg gggaccagtgccatgctgagctgtgaggtggcccaggcccagacggaggtgacgtggtac aaggatgggaagaagctgagctccagctcaaaagtgggcatggaggtcaaaggctgcaca cggaggctggtggtgctgcaggcgggcaaagcagatgctggggagtacagctgtgaggct gggggccagagagtctccttccacctgcacatcacagagcccaagggggtgtttgcgaag gagcagtcagtgcataatgaggtgaaggctgaggcggggaccagtgccatgctgagctgt gaggtggcccaggcccagacggaggtgacgtggtacaaggatgggaagaagctgagctcc agctcaaaagtaggcatggaggtcaaaggctgcacacggaggctggtggtgcagcaggtg ggcaaaacagatgctggggagtacagctgtgaggctgggggccagagagtctcctttcaa ctgcacatcacagagcccaaggcagtgtttgccaaggagcagttggtgcataatgaggtg cggactgaggcaggagccagcgccacactgagctgtgaggtggcccaggcccagacggag gtgatgtggtacaaggatgggaagaagctgagctccagttcgaaagtgcgtgtagaggcc gcaggctgcatgcggcagctggtggtgcagcaggcaggccaggcagatgctggggagtac acctgtgaggccgggggccagtggctctccttccacctggacgtttcagagcccaaggca gtgtttgcaaaggagcagccggcgcacagggaggtgcaggccgaggcggggaccattgcc acgctgagctgcgaggtggcccaggcccagacagaggtgatgtggcacaaggacgggaag aagctgagctccagctcgaaagttcgaatggaggctgtgggctgcacacggaggctggtg gtgcagcaggcgtgccaggccgacggcggggagtatagctgcgaggccggaggccagcgg ctttccttcaacctgcacgtggcagagcccaaggcggtgtttgccaaggagcagccagtg cacagggaggtgcaggcccaggcgggggccagcgccacactcagctgcgaggtggctcag gcccagacagaggtgatgtggtccaaggacgggaagaagctgagctccagctcgaaagtg cgtgtggaggctgtgggctgcacacggaggctggtggtgcagcaggcgggccaggcggac gccggagagtacagctgcgaggcggggagccagcggctctccttccacctgcatgtggca gagcccaaggcagtgtttgccaaggagcagccagcacacagggaggtgcaggctgaagca ggggctagcaccacactgagctgtgaggtggcccaggcccagacagaggtgacttggtac aaggacgggaagaagttgagctccagctcgaaagtgcatgtggaggctgcaggctgtaca cggaggctggtggtgcagcaggcaggccaggcggacgccggagagtacagctgtgaggct gggggccagcagctctccttccgcctgcacgtggcagagcccaaggcggtgtttgccaag gagcagccagcgagcagggaggtgcaggccgaggcggggaccagtgccacgctgagctgt gaggtggcccaggcccagacagaggtgacgtggtacaaggacgggaagaaactgagctcc agctcgaaagtgcgaatggaggctgtgggctgcacacggaggctggtggtgcaggaggca ggccaggcggatgccggggagtacagctgcgaggccggaggtcagcggctgtccttccgc ctgcacgtggcagagcccaaggtggtgtttgccaaggagcagccagcgcacagggagctg caggctgaggcggggaccagtgccacactgagctgcgaggtggcccaggcccagacagag gtgacgtggtacaaggacgggaagaagctgagctccagctcgaaagtgcgcgtggaggcc gtgggctgcacacggaggctggtggtgcagcaggcgggccaggcagaggccggggagtac agctgcgaggctgggggtcagcggctgtccttccgcctgcaggtggcagagcccaaggcg gtgtttgccaaggagcagccggcgcacagggaggtgcaggctgaggcagggaccagcacc acgctgagctgcgaggtggcccaagcccagacggaggtgatgtggtacaaggacgggaag aagctgagctccagctcgaaaatgcgtgtggaggccgtgggctgcacacggaggctggtg gtgcaggaggcaggccaggcggatgccggggagtacagctgcgaggctgggggccagcgg ctctccttccacctgcacgtggctgaccccaaggtggtgtttgccaaggagcagccggca tgcagggaggtgcaggcggaggcgggggccagtgccacgctgagctgtgaggtggcccag ggccagatggaggtgacatggtacaaggacgggaagaagctgagctccagctcgaaagtg cgcatggaggccaacggctgcacacggaggctggtagtgcagcaggcgggccaggcggat gctggggagtacacctgtgaggcagggggccaacggctctccttccacctgcacgtggca gagccggagccccaaatttcagagagaccctgccgcagggagcctctggtggtcaaggag catgaagacatcatcctgaccgccacgctggccacaccctctgtggccacggtgacctgg ctcaaggatggtgtggagattcgccacagcaagcggcacgagacagccagccagggggac acccacaccctgaccgtgcatggcgcccaggtgctggacagcgccatctacagctgccgg gtgggcgcagaggggcaggacttcccagtgcaggtggaagaggtggccgccaagttctgc cggctgctggagcctgtgtgcggcgagctgggtggcacggtgacactggcctgcgagcta agcccagcgtgtgcagaggtggtgtggcgctgcggcaacacgcagcttcgggtgggcaag cgcttccagatggtggctgaggggcccgtgcgctcactcactgtgttggggctgcgcgca gaggacgcaggggagtacgtgtgtgagagccgtgatgaccgcaccagtgcgcagctcacc gtcagtgtgcctcaagtggtgaagtttatgtctgggctgagcgctgtggtcgcggaggag ggcggtgaggccaccttccagtgcgtggtgtcccccagtgatgtggcagtcgtgtggttc cgggatggtgccctgcttcagcccagcgagaagtttgccatatcacagagtggcgccagc cacagcctgaccatctcaggtctggtgctggaggacgcgggccagatcaccgtggaggct gagggcgcctcatcctccgctgccctgagggtccgagaggcgcccgtgctgttcaaaaag aagctggagccgcagacggtggaggagcggagctcggtgaccctggaggtggagctgacg cggccgtggccggagctgaggtggacacggaacgcgacggccctggcgccgggaaagaac gtggaaatccacgccgagggcgcccgccaccgcctggttctgcacaacgtaggttttgcc gaccgtggcttctttggctgcgagacgccggatgacaagacacaggccaaactcaccgtg gagatgcgccaggtacggctcgtacggggcctgcaggcagtggaggcacgggagcagggc acggctaccatggaggtgcagctgtcgcatgcggacgtggagggcagctggactcgcgac ggtctgcggctccagcaggggcccacgtgccacctggctgtgcggggccccgtgcacacc ctcacactctcggggctgcgaccagaggacggtggccttatggtcttcaaggccgaaggg gtgcacacgtcggcgcggcttgtggtcaccgagctgcccgtgagcttcagccgcccgctg caggacgtggtgaccactgagaaggaaaaggttaccctggagtgcgagctgtcgcgtcct aatgtggatgtgcgctggctgaaggacggtgtggagctgcgggcaggcaagacgatggcc atcgcagcccagggtgcctgcaggagcctcaccatttaccggtgcgagtttgtggatcag ggagtgtatgtgtgtgatgcccatgatgcccagagctctgcctccgtgaaggtgcaaggc cgcaacatccagatcgtgaggcccctggaggatgtggaagtgatggagaaggacggtgcc accttctcctgtgaggtctcccacgacgaagtgcctggccagtggttccgggagggcagt aaactgcggcccactgacaacgtgcgcatccgccaggaaggaaggacatacactctcatc taccggagagtcctggcggaagatgcaggagagatccaatttgtagccgaaaatgcagaa tcgcgagcccagctcagagtgaaggagcttccagtgaccctcctgcgcccgctgcgggac aagattgccatggagaagcaccgcggtgtgctggagtgtcaggtgtcccgggccagcgcc caggtgcggtggttcaagggcagtcaggagctgcagcccgggcccaagtacgagctggtc agtgatggcctctaccgcaagctgatcatcagtgacgtccaggcagaggacgaggacacc tacacctgcgacgccggtgatgtcaagaccagtgcacagttctttgtggaagagcaatcc atcaccattgtgcggggtctgcaggacgtgacagtgatggagcccgctcctgcctggttt gagtgtgagacctccatcccctcagtgcggccacctaagtggctcctggggaagacggtg ttgcaggctggggggaacgtgggcctggagcaggagggcacggtgcaccggctgatgctg cggcggacctgctccaccatgaccgggcccgtgcacttcaccattggcaagtctcgttcc tctgcccgcctggtggtctcagacatccccgtagtcctcacacggccgttggagcccaaa acagggcgtgagctgcagtcagtggtcctgtcctgcgacttccggccagcccccaaggct gtgcagtggtacaaggatgacacgcccctgtctccctctgagaagtttaagatgagcctg gagggtcagatggccgagctgcgcatcctccggctcatgcctgccgatgctggtgtctac cggtgccaggcgggcagcgcccacagcagcactgaggtcactgtggaagcacgggaggtg acagtgacagggccgctgcaggatgcagaggccacggaggagggctgggccagcttctcc tgtgagctgtcccacgaggatgaggaggtcgagtggtcgctcaacgagatgcccttgtac aacgacagcttccatgagatctcgcacaagggccggcgccacacgctggtactgaagagc gtccggcgggctgatgcgggcatagtacgcgcctcctccctgaaggtgtcgacctatgcc cgcctggaggtccgagtgaagccggtggtgttcctgaaggcgctggatgacctgtccgca gaggagcatggcaccctggccctgcagtgtgaagtctctgaccccgaggcccatgtggtg tggcgcaaagatggtgtgcagctgggccccagtgacaagtatgacttcctgcacacggcg ggcacgcgggggctcgtggtacatgacttgacctctgaagacgccggcctgtacacctgc cacgtgggctccgaggagacccgggcccgggtcagcgtgcacgatctgcacgtgggcatc accaagaggctgaagacaatggaggtgctggaaggggagagctgcagcttcgagtgcgtt ctgtcccatgagagcaccagcgacccagccatgtggacagttggtggaaagacggtgggc agctccagccgcttccaggccacacgtcagggccgaaaatacatcctggtggtccgggag gctgcgccaagtgatgctggggaggtggtcttctctgtgcggggcctcacctccaaggcc tcactcattgtcagagagaggccggccgccatcatcaagcccctggaagaccagcgggtg gcgccaggggaggacgtggagctgcgctgtgagctgtcacgggcgggaacacctgtgcac tggctgaaggacaggaaggccatccgcaagagccagaagtacgatgtggtctgcgagggc acgatggccatgctggtcatccgcggggcctcgctcaaggacgcgggagagtacacgtgt gaggtggaggcttccaagagcacagccagcctccgtgtggaagaaaaagcaaactgcttc acagaggagctgaccaacctgcaggtggaggagaaaggcacagctgtgttcatgtgcaag acggagcgccccgcggccacagtgagctggcgcaagggcctcttggagctacgggcctca cggaagcaccagcccagccaggagggcctggtcctgcggctcaccatcagtgccctggag aaggcagacagcgacacctatacctgcgacattggccaggcccagtcccaggcccagctc ctagtgcaaggccggagagtgcatatcatcgaggacctggaggacgtggatgtgcaggag ggctcctcggccaccttccgttgccggatctccccggccaactacgagcctgtgcactgg ttcctggacaagacacccctgcatgccaacgagctcaatgagatcgaggcccagcccggg ggctaccacgtgctgaccctgcggcagctggcgctcaaggactcgggcaccatctacttt gaggcgggtgaccagcgggcctcggccgccctgcgggtcactgagaaaccaagcgtcttc tcccgggagctcacagatgccaccatcacagagggtgaggacttgaccctggtgtgcgag accagcgcctgcgacattcctgtgtgctggaccaaggatgggaagaccctgcgggggtct gcccggtgccagctgagccacgagggccaccgggcccagctgctcatcactggggccacc ctgcaggacagcggacgctacaagtgtgaggctgggggcgcctgcagcagctccattgtc agggtacacgcgcggccagtgcggttccaggaggccctgaaggatctggacgtgccggag ggtggtgctgccacactgcgctgtgtgctgtcgtctgtggctgcgcccgtgaagtggtgc tgtggaaacaacgtcctgaggccaggtgacaaatacagcctacgccaggagggtgccgtg ctggagctggtggtccggaacctcaggccgcaggacagcgggcagtactcatgctccttc ggggaccagactacttctgccaccctcacggtgactgccctgcctgcccagttcatcagg aaactgagaaacaaggaggccacagaaggggccacggccacgctgcggtgtgagctgagc aaggcggccccggtggagtggagaaaggggtctgagaccctcagagatggggacagatac tgcctgaggcaggacggggccatgtgtgagctgcagatctgtggcctggccatggtggat gccggggagtactcgtgtgtgtgtggagaggagaggacctcggcctcactcaccatcagg gccatgcctgcccacttcataggaagactgagacaccaagagagcacagaaggggccaca gccacgctgcggtgtgagctgagcaaggcggcccccgtggagtggaggaaggggcatgag agcctcagagatggggacagacacagcctgaggcaggacggggctgtgtgcgagctgcag atctctggcctggctgtggcagatgctggggagtactcctgtgtgtgtggggaggagagg acctctgccactctcaccgtgaaggccctgccagccaagttcacagagggtctgaggaat gaagaggccgtggaaggggccacagccatgttgtggtgtgaactgagcaaggtggcccct gtggagtggaggaaggggcccaagaacctcagagatggggacagatacatcctgaggcag gaggggaccaggtgtgagctgcagatctgtggtctggccatggcggacgccggggaatac ttgtgtgtgtgcgggcaggagaggacctcagccacgctcaccatcagggctctgcctgcc aggttcatagaagatgtgaaaaaccaggaggccagagaaggggccacggtcatgctgcag tgtgagttgaacagtgcagcccctgtggagtggaggaaggggtctgagacgcttagagat ggggacagatacagcctgaggcaggacgggaccaaatgtgagctgcagattcgtggcctg gccatggcagacactggggagtactcgtgcgtgtgcgggcaggagaggacctcagccatg ctcaccgtcagggctctacccatcaagttcacagagggtctgaggaacgaagaggccaca gaaggggcaacggccacgctgcggtgtgagctgagcaagatggcccccgtggagtggtgg aaggggcatgagaccctcagagatggagacagacacagcctgaggcaggacggggccaag tgtgagctgcagatccgtggcctggtggcagaggacgctggggagtacctgtgcatgtgc gggaaggagaggacctcagccacgctcaccgtcagggccctgccttccaagttcatagag ggtctgaggaatgaagaggccacagaaggggtcacggccacgctgcagtgtgagctgagc aaggcagcaccggtggagtggaggaaggggcatgagaccctcagagatggggacagacac agcctgaggcaggacgggtccaggtgtgagctgcagatccgtggcctggctgtggtggat gccggggagtactcgtgtgtgtgcgggcaggagaggacctcggccacactcactgtcagg gccctgcctgccagattcatagaagatgtgaaaaaccaggaggccagagaaggggccacg gtcgtgctgcaatgtgagctgagcaaggcggcccccgtggagtggaggaaggggtctgag accctcagaggtggggacagatacagcctgaggcaggacgggaccagatgtgagctgcag attcgtggcctgtccgtggcagacactggagagtactcgtgtgtgtgcgggcaggagagg acctcggccacactcaccgtcagggccctgcctgcacgattcactcaagatctgaagacc aaggaggcctcagaaggggccacagctacactgcagtgtgagctgagcaaggtggcccct gtggaatggaagaagggtcctgagaccctcagagatggcggcagatacagcctgaagcag gatgggacgaggtgtgagctgcagatccatgacctgtctgtggcggatgctggggaatac tcatgcacgtgtggacaagagaggacctcggccacgctcaccgtcagggccctgcctgcc aagttcacagcgggtctgaggaatgaagaggccacggagggggccacagccacactgcaa tgtgagctgagcaaggcagcccctgtggagtggaggaaaggcctcgaggctctcagagat ggggacaaatacagcctgagacaagacggggctgtgtgtgcgctgcagattcatggcctg gctgtggcagataccggggtgtactcatgtgtgtgtgggcaggagaggacctcagctaca ctcactgtcagggccctgcctgccagattcatagaggatatgagaagccagaaggccaca gaaggggctacagtcacactgcaatgtaagctgagaaaggcggcccccgtggagtggaga aaggggcccaacaccctcaaagatggggacagatacagcctgaagcaggatgggaccagg tgtgagctgcagattcgtggcctgatcatagcagatgctggagaatactcatgcatatgt gagcaggagaggacctcggccatgctcactgtcagggccctgccggccagattcatagaa gatgtgagaaatcatgaggccacagaaggggccacggctgtgctgcagtgtgagctgagc aaggcggcccctgtggagtggcggaaggggtctgagaccctcagagatggggacagatat agcctgaggcaggacgggacgaggtgtgagctgcagattcatggcctggctatggaggac actggagagtatttgtgtgtgtgcgggcaggagaggacctcagctacactcactgtcagg gccctgccggccagattcatagacaacatgacaaaccaggaggccagagaaggggccacg gccacactgcagtgtgaactgagcaaggcggcccctgtggagtggagaaagggacctgaa acactccaagatggggacagacacagcctgaggcaggacgggaccaggtgtgagctgcag attcgtggcctggctgtggcagatgctggggaatactcgtgcgtgtgtgggcaggagagg acctcggccatgctcaccatcagggccctgcccgccaagttcacaaagggtctgacaaat gaagaggccacagaaggggccacggctgtgctgcagtgtgagctgagcaaggcggcccct gttgagtggaggaagggacctgaaaccctcagaggtggggacagatacaacctgaggcag gatgggaccagatgtgagctgcagattcatggcctgtccgtggcagacactggagagtac tcatgtgtatgtggtcaggagaagacatcagccactctcattgtcaaggccccacaccca gtgttccgggagccactgcagagtctgcaggcagaagagggctccacagccaccctgcag tgtgagctgtctcagcccactgctacagtggtctggagcaagggtggcctgcagttgcag gccaatgggcgccgggagccacggcttcagggctgcaccgcagagctggtgttacggggc ctacaacgtgaagacactggcgaatacacttgcacctgtggctcccaggccaccagtgca accctcactgtcacagctgcgcctgtgtggttcctccgagagctgcagccccaggaggtg gatgagggaggcactgcacacttacgctgcgagctgagccgggcgggtgcgagcgtggag tggcgcaagggctccctacagctcttcccttgtgccaagtaccagatggtgcaggatggt gcagctgcagagctgctggtgtgcggagtggagcaggaggatgagggtgactacacttgc gacacgggccacacgcagagcatggccagcctctctgtctgtgtccccaggcccaagttc aagacccggcttcagagtctggagcaggagacaggtgacatagcccggctgtgctgtcag ctgagtgatgcagagtcgggggccatggtgcaatggctcaaggagggcgtggagctgcat gcgggccccaagtacgagattcggagccaaggggccacgcgggagctgcttatccaccaa ctggaggccaaggacacgggcgagtatgcctgtgtgacaggcggccagaaaactgctgcc tccctcagggtcacagagcctgaggtgaccattgtacaggggctggttgatgcggaggtg ccggccgatgaggatgttgagttcagctgcgaggtgtccagggctggagccacaggcgtg cagtggtgcctacagggcctgccactgcaaagcaatgaggtgacagaggtggctgtgcgg gatggccgcatccacaccctgcggctgaagggcgtgacgcccgaggacgctggcactgtc tccttccatttgggaaaccatgcttcctctgcccagctcaccatcagagctcctgaggtg accatcctggagcccctgcaggatgtacagctcagtgagggccaggatgccagcttccag tgccggctatccagagcttcaggccaggaagcccgctgggctttgggaggggtgcccctg caggccaacgagatgaatgacattgctgtggagcagggcgcactccacctgctcaccctg cacaaggtaaccctcgaggatgctggaactgtcagtttccacgtgggcacatgtagctct gaggcccagctgaaagtcacagccaagaacacggtggtgcgggggctggagaatgtggag gcactggagggtggcgaggcgctgttcgagtgccagctgtcccagcccgaggtggccgcc cacacctggctgctggatgacgaacccgtgcgcacctcggagaacgccgaggtggtcttc ttcgagaatggcctgcgccacctgctgctgctcaaaaacttgcggccacaagacagctgc cgggtgaccttcctggctggggatatggtgacgtccgcgttcctcacggtccgaggctgg cgcctggagatcctgaagcctctgaaaaacacggcggtccgggccggcgcgcaggcccac ttcacctgcacactcagcgaggcggtgcccgtgggagaggcgtcctggtactttaatggc gcggcggtgcagccagatgacagcgactggactgtcaccgccgacggcagtcaccacgcc ctactgctgcacagcgcccagccccaccacgccggggaggtcaccttcgcttgccgcgac gccgtggcctctgcacggctcaccgtgctgggcctccctgatcccccagaggatgctgag gtggtggctcgcagcagccacactgtgacactgtcttgggcagctcccatgagtgatgga ggcggtggtctctgtggctaccgcgtggaggtgaaggagggggccacaggccagtggcgg ctgtgccacgagctggtgcctggacccgagtgtgtggtggatggcctggcccccggggag acctaccgcttccgtgtggcagctgtgggccctgtgggtgccggggaaccagttcacctg ccccagacagtgcgacttgcagagccaccgaagcctgtgcctccccagccctcagcccct gagagccggcaggtggcagctggtgaggatgtctgtctggagcttgaggtggcagctgag gctggcgaggtcatctggcacaagggaacggagcgcatccagcccagtgggcggttcgag gtggtctcccagggtcggcaacagatgctggtgatcaggggcttcacggcagaagaccag ggcgagtaccactgtggcctggcccagggctccacctgccccgcggctgccaccttccag gtggcactgagcccagcctctgtggatgaggctcctcctcagcccagcctgccccccgag gcagcccaggagggtgacctgcatctactgtgggaggccctggctcggaaacgtcgcatg agccgtgagcccacgctggactccattagcgagctgcctgaggaggacggccgctcacag cgcctgccacaggaggcagaggaggtggcacctgatctctccgaaggctactccacggcc gatgagctggcacgcactggagatgctgacctctcacacaccagctctgatgatgagtcc cgggcaggcaccccttccctggtcacctacctcaagaaggctgggaggccaggcacctca tcactggccagcaaggttggggccccagcagccccctctgtgaagccacagcagcagcag gagccactggctgctgtgcgcccaccactgggagacctgagcaccaaagacctgggtgat ccctcaatggacaaggcagctgtgaagatccaggccgcctttaagggctacaaggtccgg aaggagatgaaacagcaggaagggcccgtgttctcccacacatttggggacaccgaggca caggtgggggatgccctgcggctggagtgtgttgtggctagcaaggcagatgtgcgagcc cgctggctgaaggatggtgtggagctgaccgacgggcggcaccatcacatcgaccagctt ggggatggcacttgctctctgttgatcactggcctgggccgtgctgatgctggctgctac acctgtcaggtgagcaacaagtttggccaggtggcccacagtgcctgtgtggtggtcagt gggacagagagtgaagccgagagttcctctgggggtgagctggacgatgccttccgccgg gctgcccggcggctgcaccggctcttccgcaccaaaagttcgactgaagtttcagacgag gagctcttcctgagtgcagaagagggccctgcagagccagaggagcccgtggactggcag acataccgcgaagatgagcatttcatctgcatctgttttgaggcgctcactgaggcccgc caggcggtaactcgcttccaggagatgtttgccacactgggcatcggggtggagatcaag ctggtggaacagggacctcggagagtagagatgcgcatcagcaaagagacccccgctcct gtggtacctccagagccattgcccagcctactgacttctgacgccgccccagtgttcctg accgagttgcagaaccaagaagtgcaggatgggtatcctgtgagctttgactgcgtggtg acaggtcagcccgtgcccagtgtgcgctggttcaaggatgggaagttgttggaggaggat gaccactacatgattaatgaagaccaacagggtggccatcagctcatcatcacagccgtg gtgccagcagacatgggcgtctaccgctgcctggccgagaacagcatgggtgtctcctcc accaaggctgagctccgtgtggacttgacaagcacagactatgacactgcagcggatgcc acggagtcctcatcctacttcagtgcccaaggctacctgtccagccgggagcaggaggga acagagtccaccactgacgagggccagctgccccaggtggtggaggagctgagagacctc caggtggcccctggcacacgcctggccaagttccagctcaaggtgaaaggctaccctgct cccagattatactggttcaaagatggccagcccctgaccgcatctgcccacatccgcatg actgacaagaagaccctgcacaccctggagatcatctcagtcatccgggaggactctggc cagtatgcagcctacatcagcaatgccatgggtgctgcctactcatctgcccggctgctg gttcgaggccctgatgagccagaagagaagcctgcatcagatgtgcatgagcaactggtg ccaccccgaatgctggagaggttcacccccaagaaagtgaagaaaggctccagcatcacc ttctccgtgaaggtagaaggacgcccggcgcccaccgtgcactggctcagggaggaagct gagaggggcgtgctgtggattggccctgacacgccgggctacaccgtggccagctctgcg cagcagcacagcctggtcctgctggacgtgggccggcagcaccagggcacctacacatgc attgccagcaacgctgctggccaggccctctgctccgccagcctgcacgtctcaggcttg cctaaggtggaggagcaggagaaagtgaaggaagcactgatttccactttcctgcagggg accacacaagctgtctcagcacaggggttggaaactgcgagttttgctgaccttggtggg cagaggaaaggagagcctctggctgccaaggaggccctcggccatctgtccctcgctgag gtgggcacagaggagttcctgcagaaactgacctcccagatcaccgagatggtatcggcc aagatcacgcaggccaagctgcaggtgcctggaggcgacagcgatgaggactccaagacg ccatctgcatccccccgccatggccgatcacggccatcctccagcatccaggagtcttcc tcagagtcagaggacggcgatgcccgaggcgagatctttgacatctacgtggtcactgcc gactacctgcccctaggggctgagcaggatgccatcgcgctgcgggaaggccagtacgtg gaggtcctggatgcagcccacccactgcgctggcttgtccgcaccaagcccaccaagtcc agcccctcacggcagggctgggtgtcaccagcctacctggacaggaagctcaagctgtca cctgagtggggggccgccgaggcccctgagttccctggggaggctgtgtctgaagacgaa tacaagtcaaggctgagttctgtgatccaggagctgctgagttctgagcaggccttcgtg gaggagctgcagttcctgcagagccaccacctgcagcacctggagcgctgcccccacgtg cctgcagctgtggccggccagaaggcagtcatcttccgcaatgtgcgggacatcggccgc ttccacagcagcttcctgcaggagctgcagcagtgcgacacggacgacgacgtggccatg tgcttcatcaagaaccaggcggcctttgagcagtacctggagttcctggtggggcgtgtg caggctgagtcggtggtcgtcagcacggccgtccaggagttctacaagaaatatgcggag gaggccctgttggcaggggacccctctcagcccctgccaccacctctgcagcactacctg gagcagccagtggagcgggtgcagtgctaccaggccttgctgaaggagctgatccgcaac aaggcgcggaacagacagaactgcgcgctgctggagcaggcctatgccgtggtgtctgcc ctgccgcagcgcgccgagaacaagctgcatgtgtccctcatggagaactacccaggcacc ctggaggccctgggcgagcccatccgccagggccacttcatcgtgtgggagggtgcgccg ggggcccgcatgccctggaagggccacaaccgtcacgtgttcctcttccgcaaccacctg gtaatctgcaagccccggcgagactctcgcaccgataccttcagctacgtgttccggaac atgatgaagctgagcagcatcgacctgaacgaccaggtggagggggatgaccgcgccttc gaggtgtggcaggagcgggaggactcagtgcgcaagtacctgctgcaggcacggacagcc attatcaagagctcatgggtgaaagagatctgtggcatccagcagcgtctggccttgcct gtgtggcggcccccggactttgaagaggagctggccgactgcacagccgagctgggcgag acagtcaagctggcctgccgcgtgacgggcacacccaagcctgtcatcagctggtacaaa gatgggaaaccagtgcaggtggacccccaccacatcctcattgaagaccccgatggctcg tgtgccctcatcctggacagcctgaccggtgtggactctggccagtacatgtgcttcgcg gccagcgccgctggcaactgcagtaccctgggcaagatcctggtgcaagtcccaccacgg ttcgtgaataaggtccgggcctcgccctttgtggagggagaggacgcccagttcacctgc accatcgaaggcgccccgtacccgcagatcaggtggttcaaggacggggccctgctgacc cctggcagcaagttccagacactgagtgagcctcgcagcggcctgctagtgctggtgatc cgggcggccggcgaggaggacctggggctctacgagtgtgagctggtgaaccggctgggc tccgcgcgggctactgcggagctgcacatgcagagccccacgctgcaggcccgggagcag taccacagggagcagctcgcagctgcagtggaagacaccaccctggagagagcagaccag gagatcacatccatcctgaagagactgctgggccccaaggcgccaggcccctccacaggg gacctcactggccccgacccctgccccgggggggcacctgcactccaggaaactggctcc cagcccccagtcaccggaactttggaggcacctgccgtgcccccgagggtgccacagccc ctcctccacgaaggcccagagcaggagccggaagccattgccagagcccaggaatggact gtgcccattcggatggagggtgcagcctggcccggggcaggcacaggggagctgctctgg gacgtccacagccacgtggtcacggagaccacgcagaggacctacacataccaggccatc gacaagcacaccgcacggcccccatccatgcaggtaaccatcgaggatgtgcaggtacag acaggcggaacggcccaattcgaggctatcattgagggtgacccacagccctcggtgacc tggtacaaggacagcatccagctggtggacagcacccggcttagccaacagcaagaaggc accacatactccctggtgctgaggcatgtggcctcgaaggatgccggcgtttacacctgc ctggcccaaaatgctggtggccaggtgctctgcaaggcagagctgttggtgcttgggggg gacaatgagccggactcagagaagcaaagcccccggaggaagctgcactccttctatgag gtcaaggaggagattgggaggggcgtgtttggcttcgtgaaaagagtgcagcacaaagga aacaagatcttctgcgctgccaagttcatccccctacggagcagaactcgggcccaggca tacagggagcgagacatcctggccgcgctgagccacccgctggtcacggggctgctggac cagtttgagacccgcaagaccctcatcctcatcctggagctgtgctcgtccgaggagctg ctggaccgcttgttcaggaagggcgtggtgacggaggccgaggtcaaggtctacatccag cagctggtggaggggctgcactacctgcacagccatggcgttctccacctggacataaag ccctctaacatcctgatggtgcatcctgcccgggaaaacattaaaatctgcgacttcggc tttgcccagaacatcaccccagcagagctgcagttcagccagtacgggtcccctgagttc gtctcccctgagatcatccagcagaaccctgtgagcgaggcctccgacatctgggccatg ggtgtcatctcctacctcagcctgacctgctcatccccatttgccggcgagagtgaccgt gccaccctcctgaacatcctggaggggcgtgtgtcatggagcagccccatggctgcccac ctcagcgaagatgccaaagacttcatcaaggctacgctgcagaaagcccctcaggcccgg cctagtgcggcccagtgcctctcccatccctggttcctgaaatccatgcctgcggaggag gcccacttcatcaacaccaagcagctcaagttcctcctggcccgaagtcgctggcagcgt tccctgatgagctacaagtccatcctggtgatgcgctccatccctgagctgctgcggggc ccgcccgacagcccctccctcggcgtggcccggcacctctgcagggacactggtggctcc tccagttcctcctcctcctctgacaacgagctcgccccattcgcccgggctaagtcactg ccaccctccccggtgacacactcgccactgctgcacccccggggcttcctgcggccctcg gccagcctgcctgaggaggctgaggccagtgagcgctccaccgaggccccagctctgcct gcatctcccgagggtgccgggccaccggccgcccagggctgcgtgccccggcacagcgtc atccgcagcctcttctaccagcaggcgggtgagagccctgagcgcggggccctggccccg gggagcaggcggcacccggcccggcggcggcacctgctgaagggcgggtacattgctggg gcgctgcctggcctgcgcgagccactgatggagcaccgcgtgctggaggaggaggccgcc acggaggagcagaccaccctcctggccaaagccccctccttcgagaccgccctccggctg cctgcctctggcacccactgggcccctggccgcagccgctccctggaacatgaccctccg agcaccccccgcccttccctggaggcctgctgtgaggcacagcgactgccttcagccccc tctaggggggcccctatcagggacatggggcaccctcagggctccaagcagctcccatcc actggtggccacccaggcactgctcagccagagaggccatccccggacagcccttggggg cagccagcccctttctcccaccccaagcagggttctgccccccaggagggctgcagcccc cacccagcagttgccccatgccttcctggttccttccctccaggatcttgcaaagaggcc cccttagtaccctcgagccccttcttgggccagccccaggcaccccctgcccctgccaaa gctagccccccactagactctaagatggggcctggagacatctctcttcctgggaggcca aaacccggcccctgcagttccccagggtcagcctcccaggcgagctcttcccaagtgagc agggtgggctcctcccaggtgggcacagagcctggtccctccctggacgctgagggctgg tcccaggaggctgaggatctgtccgactccacacccaccttgcagcggcctcaggaacag gcgaccatgcggaagttctccctggggtgtcgcgggggctacgcaggcgtggctggctat ggcacctttgcctttggtggagatgcggggggcatgctggggcaggggcccatgtgggcc aggatagcctgggctgtgtcccagtcggaggaggaggagcaggaggaggccagggctgag tcccagtcggaggagcagcaggaggcagccagggctgagagcccgctgccccaggtcagt gcaaggcctgtgcctgaggtcggcagggctccctccaggacctctccagagcccaccccg tgggaggacgtcgggcaagtctccctggtgccgatccaggacctgtcaggtgatgcagag gcggccgacacaatatccctggacatttccgaggtggaccccgcctacctcaacctctca gacttgtacgatatcaagtacctcccatttgagtttatgatcttcaggaaagtccccaag cctgctcagctagagccgccctcccccatggctgaggaggagctggccgagttcccggag cccatgtggccctggccaggtgaactgggcccccacgcaggcctggagatcacagaggag ccagaggacgtggatgcgctgctggcggaggctgctgtgggcaggaagcgcaagtggtcc tcgccatcacgcagtctcttccacttccctgggaggcacctgccactggacgagcccgca gagctggggctgcgtgagagagtgaaggcctctgtggagcacatctcccggatcctgaag ggcaggccggaaggtctggagaaggaggggccccccaggaagaagccaggccttgcttcc ttccggctctcaggtctgaagagctgggacagagcgccgacattcctaagggagctctca gatgagactgtggtcctgggccagtcagtgacgctggcctgccaggtgtcagcccagcca gctgcccaggccacctggagcaaagacggagcccccctggagagcagcagccgtgtcctc atctctgccaccctcaagaacttccagcttctgaccatcctggtggtggcggctgaggac ctgggtgtgtacacctgcagcgtgagcaatgcgctggggacagcgaccaccacgggcgtc ctccggaaggcagagcgcccctcatcctcgccatgcccggatatcggggaggtgtacgcg gatggggtgctgctggtctggaagcccgtggaatcctacggccctgtgacctacattgtg cagtgcagcctagaaggtggcagctggaccacactggcctccgacatctttgactgctgc tacctgaccagcaagctctcccggggcggcacctacaccttccgcacggcatgtgtcagc aaggcaggaatgggcccctacagcagcccctcggagcaagtcctcctgggagggcccagc cacctggcctcagaggaggagaaccaggggcggtcagcccaacctctgcccagcacaaag accttcgcattccagacacagatccggaggggccgcttcagtgtggtgcggcagtgctgg gagaaggccagcgggcgggcactggccgccaagatcatcccttaccgccccaaggacaag acagcagtgctgcgcgaatacgaggccctcaagggcctgcaccacccgcacctggcccag ctgcacgcagcctacctcagcccctggcacctggtgctcatcttggagctgtgctctggg cctgagctgctcccctgcctggccgagagggcctcctactcagaatccgaggtgaaggac tacctgtggcagatgctgagcgccacccagtacctgcatacccagcacatcctgcacctg gacctgaggtccgagaacatgatcatcaccgaatacaacctgctcaaggtcgtggacctg ggcaatgcacagagcctcagccaggagaaggtgctgccctcagagaagttcaaggactac ctagagaccatggagctcctggagggccagggggctgttccacagacagacatctgggcc atcggtgtgacagccttcatcatgctgagcgccgagtacccggtgagcagcgagggtgca cgcgacctgcagagaggactgcgcaaggggctggtccagctgagccgctgctacgcgggg ctgtccggaggcgccgtggccttcctacgcagtactctgtgcgcccagccctggggccgg ccctgtgcgtccagctgcctgcagtgcccgtggctaacagaggaaggcccggcctgttcg cggcccgcgcccgtgaccttccctaccgcgcggctgcgcgtcttcgtgcgcaatcgcgag aagagacgggcgctgctgtacaagaggcacaacctggcccaggtgcgctga

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