Porphyromonas sp. oral taxon 275: J4862_03635
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Entry
J4862_03635 CDS
T08761
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
porp
Porphyromonas sp. oral taxon 275
Pathway
porp00010
Glycolysis / Gluconeogenesis
porp00020
Citrate cycle (TCA cycle)
porp00620
Pyruvate metabolism
porp00785
Lipoic acid metabolism
porp01100
Metabolic pathways
porp01110
Biosynthesis of secondary metabolites
porp01120
Microbial metabolism in diverse environments
porp01200
Carbon metabolism
porp01210
2-Oxocarboxylic acid metabolism
Module
porp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
porp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
J4862_03635
00020 Citrate cycle (TCA cycle)
J4862_03635
00620 Pyruvate metabolism
J4862_03635
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
J4862_03635
Enzymes [BR:
porp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
J4862_03635
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
XFP_N
Motif
Other DBs
NCBI-ProteinID:
QUB43719
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Position
913332..914300
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AA seq
322 aa
AA seq
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MAKLKKEDLLEMYRKMEDIRNFDNKVNQLVRRGEVPGMTHFSVGEEAANVGAICGLEKGD
LITSNHRGHGQSIAMGIDLNGMMAEIMGKANGVCKGKGGSMHIADVDAGNLGANGIVGGG
MGIAIGAALTQKMKKTGKIVICCFGDGATNEGSFHETLNMAAIWDLPVIFYCINNGYGIS
TPISSVMRTKHVYERAAAYGVPGVFIEDGNDVMAVRETMDKVIKDVRAGKGPVLVEAISY
RWYGHSTSDPGKYRTKEEVDEWKKKDPILKFRNYLVDKKLATTEELDALEAASHAAVDEA
VDFGRKGPEPAPESAFEDIFTE
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggcaaagcttaagaaagaagatctgctggagatgtaccgcaagatggaggatatccgc
aacttcgacaacaaggtgaaccagctggtgcgccgaggcgaagtccctgggatgacccac
ttctccgtaggggaggaggccgctaacgtcggtgctatctgcgggctcgagaagggtgac
ctcatcacctccaaccaccgtggtcacggtcagagtatcgctatggggatcgacctcaat
ggcatgatggctgagatcatgggtaaggccaatggtgtctgtaagggtaagggtggctcg
atgcacatcgcagacgtagacgctggtaacctcggtgccaacggtatcgtaggtggtggt
atgggtatcgccatcggtgcagccctcacgcagaagatgaagaagacgggcaagatcgtc
atctgctgcttcggtgatggggctaccaacgaaggctccttccacgagaccctcaatatg
gcagcgatctgggatcttcccgtgatcttctactgtatcaataacggctacggtatctct
acgcccatcagctccgtgatgcgcaccaagcacgtctatgagcgtgcagctgcctacggc
gtccccggggtcttcatcgaggatggtaacgatgtgatggccgtacgtgagaccatggat
aaggtgatcaaggacgtccgcgcaggcaagggtcccgtgctcgtcgaggctatctcctac
cgctggtatggccactcgacctccgaccccggtaagtaccgcaccaaggaagaggtagac
gagtggaagaagaaggatcctatcctcaagttccgcaactatctcgtcgacaagaagctc
gccacgaccgaggagctcgatgccctcgaggctgctagccatgcagccgttgatgaggct
gtcgacttcggccgcaagggaccagagcccgctcccgagtctgccttcgaggatatcttc
accgaatag
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