KEGG   Panthera pardus (leopard): 109246747
Entry
109246747         CDS       T06062                                 
Symbol
RELA
Name
(RefSeq) transcription factor p65 isoform X1
  KO
K04735  transcription factor p65
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad01523  Antifolate resistance
ppad04010  MAPK signaling pathway
ppad04014  Ras signaling pathway
ppad04024  cAMP signaling pathway
ppad04062  Chemokine signaling pathway
ppad04064  NF-kappa B signaling pathway
ppad04066  HIF-1 signaling pathway
ppad04071  Sphingolipid signaling pathway
ppad04137  Mitophagy - animal
ppad04151  PI3K-Akt signaling pathway
ppad04210  Apoptosis
ppad04211  Longevity regulating pathway
ppad04218  Cellular senescence
ppad04380  Osteoclast differentiation
ppad04613  Neutrophil extracellular trap formation
ppad04620  Toll-like receptor signaling pathway
ppad04621  NOD-like receptor signaling pathway
ppad04622  RIG-I-like receptor signaling pathway
ppad04623  Cytosolic DNA-sensing pathway
ppad04625  C-type lectin receptor signaling pathway
ppad04657  IL-17 signaling pathway
ppad04658  Th1 and Th2 cell differentiation
ppad04659  Th17 cell differentiation
ppad04660  T cell receptor signaling pathway
ppad04662  B cell receptor signaling pathway
ppad04668  TNF signaling pathway
ppad04722  Neurotrophin signaling pathway
ppad04917  Prolactin signaling pathway
ppad04920  Adipocytokine signaling pathway
ppad04926  Relaxin signaling pathway
ppad04931  Insulin resistance
ppad04932  Non-alcoholic fatty liver disease
ppad04933  AGE-RAGE signaling pathway in diabetic complications
ppad04936  Alcoholic liver disease
ppad05010  Alzheimer disease
ppad05022  Pathways of neurodegeneration - multiple diseases
ppad05030  Cocaine addiction
ppad05132  Salmonella infection
ppad05133  Pertussis
ppad05134  Legionellosis
ppad05135  Yersinia infection
ppad05140  Leishmaniasis
ppad05142  Chagas disease
ppad05145  Toxoplasmosis
ppad05146  Amoebiasis
ppad05152  Tuberculosis
ppad05160  Hepatitis C
ppad05161  Hepatitis B
ppad05162  Measles
ppad05163  Human cytomegalovirus infection
ppad05164  Influenza A
ppad05165  Human papillomavirus infection
ppad05166  Human T-cell leukemia virus 1 infection
ppad05167  Kaposi sarcoma-associated herpesvirus infection
ppad05168  Herpes simplex virus 1 infection
ppad05169  Epstein-Barr virus infection
ppad05170  Human immunodeficiency virus 1 infection
ppad05171  Coronavirus disease - COVID-19
ppad05200  Pathways in cancer
ppad05202  Transcriptional misregulation in cancer
ppad05203  Viral carcinogenesis
ppad05207  Chemical carcinogenesis - receptor activation
ppad05208  Chemical carcinogenesis - reactive oxygen species
ppad05212  Pancreatic cancer
ppad05215  Prostate cancer
ppad05220  Chronic myeloid leukemia
ppad05221  Acute myeloid leukemia
ppad05222  Small cell lung cancer
ppad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppad05321  Inflammatory bowel disease
ppad05415  Diabetic cardiomyopathy
ppad05417  Lipid and atherosclerosis
ppad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109246747 (RELA)
   04014 Ras signaling pathway
    109246747 (RELA)
   04064 NF-kappa B signaling pathway
    109246747 (RELA)
   04668 TNF signaling pathway
    109246747 (RELA)
   04066 HIF-1 signaling pathway
    109246747 (RELA)
   04071 Sphingolipid signaling pathway
    109246747 (RELA)
   04024 cAMP signaling pathway
    109246747 (RELA)
   04151 PI3K-Akt signaling pathway
    109246747 (RELA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    109246747 (RELA)
  09143 Cell growth and death
   04210 Apoptosis
    109246747 (RELA)
   04218 Cellular senescence
    109246747 (RELA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    109246747 (RELA)
   04620 Toll-like receptor signaling pathway
    109246747 (RELA)
   04621 NOD-like receptor signaling pathway
    109246747 (RELA)
   04622 RIG-I-like receptor signaling pathway
    109246747 (RELA)
   04623 Cytosolic DNA-sensing pathway
    109246747 (RELA)
   04625 C-type lectin receptor signaling pathway
    109246747 (RELA)
   04660 T cell receptor signaling pathway
    109246747 (RELA)
   04658 Th1 and Th2 cell differentiation
    109246747 (RELA)
   04659 Th17 cell differentiation
    109246747 (RELA)
   04657 IL-17 signaling pathway
    109246747 (RELA)
   04662 B cell receptor signaling pathway
    109246747 (RELA)
   04062 Chemokine signaling pathway
    109246747 (RELA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    109246747 (RELA)
   04917 Prolactin signaling pathway
    109246747 (RELA)
   04926 Relaxin signaling pathway
    109246747 (RELA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    109246747 (RELA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109246747 (RELA)
  09149 Aging
   04211 Longevity regulating pathway
    109246747 (RELA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109246747 (RELA)
   05202 Transcriptional misregulation in cancer
    109246747 (RELA)
   05207 Chemical carcinogenesis - receptor activation
    109246747 (RELA)
   05208 Chemical carcinogenesis - reactive oxygen species
    109246747 (RELA)
   05203 Viral carcinogenesis
    109246747 (RELA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109246747 (RELA)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    109246747 (RELA)
   05221 Acute myeloid leukemia
    109246747 (RELA)
   05220 Chronic myeloid leukemia
    109246747 (RELA)
   05215 Prostate cancer
    109246747 (RELA)
   05222 Small cell lung cancer
    109246747 (RELA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109246747 (RELA)
   05170 Human immunodeficiency virus 1 infection
    109246747 (RELA)
   05161 Hepatitis B
    109246747 (RELA)
   05160 Hepatitis C
    109246747 (RELA)
   05171 Coronavirus disease - COVID-19
    109246747 (RELA)
   05164 Influenza A
    109246747 (RELA)
   05162 Measles
    109246747 (RELA)
   05168 Herpes simplex virus 1 infection
    109246747 (RELA)
   05163 Human cytomegalovirus infection
    109246747 (RELA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109246747 (RELA)
   05169 Epstein-Barr virus infection
    109246747 (RELA)
   05165 Human papillomavirus infection
    109246747 (RELA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109246747 (RELA)
   05135 Yersinia infection
    109246747 (RELA)
   05133 Pertussis
    109246747 (RELA)
   05134 Legionellosis
    109246747 (RELA)
   05152 Tuberculosis
    109246747 (RELA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    109246747 (RELA)
   05145 Toxoplasmosis
    109246747 (RELA)
   05140 Leishmaniasis
    109246747 (RELA)
   05142 Chagas disease
    109246747 (RELA)
  09163 Immune disease
   05321 Inflammatory bowel disease
    109246747 (RELA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109246747 (RELA)
   05022 Pathways of neurodegeneration - multiple diseases
    109246747 (RELA)
  09165 Substance dependence
   05030 Cocaine addiction
    109246747 (RELA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109246747 (RELA)
   05418 Fluid shear stress and atherosclerosis
    109246747 (RELA)
   05415 Diabetic cardiomyopathy
    109246747 (RELA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109246747 (RELA)
   04932 Non-alcoholic fatty liver disease
    109246747 (RELA)
   04931 Insulin resistance
    109246747 (RELA)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109246747 (RELA)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    109246747 (RELA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ppad03000]
    109246747 (RELA)
Transcription factors [BR:ppad03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    109246747 (RELA)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer
Other DBs
NCBI-GeneID: 109246747
NCBI-ProteinID: XP_019270537
Ensembl: ENSPPRG00000003615
LinkDB
Position
Unknown
AA seq 555 aa
MDDLFPLIFPTEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFNGPTDPRPPPRRIAVPSRSSAAVPKPAPQPYPFTPSLSTINF
EEFSPMVFSSGQIPSQTPALAPAPAPILAPAPASVPAPAPVPAPXPAPAPAPAPILAPGL
AQAVVPPAPKTTQAGEGTLTEALLQLQFDADEDLGALLGNSADPAVFTDLASVDNSEFQQ
LLNQGVSVAPHPAEPMLMEYPEAITRLVTGSQRPPDPAPAPLGASGLPNGLLSGDEDFSS
IADMDFSALLSQISS
NT seq 1668 nt   +upstreamnt  +downstreamnt
atggacgacctgtttcccctcatcttcccgactgagccggcccaggcctctggcccttat
gtggagatcatcgagcagcccaagcagcggggcatgcgcttccgctacaagtgcgagggt
cgctccgcgggcagtatccccggcgagaggagcacggataccaccaagacccaccccacc
atcaagatcaatggctacaccgggccagggacagttcgcatctcattggtcaccaaggac
ccccctcatcggcctcacccccatgagctggtgggaaaagactgccgggatggcttctat
gaggctgagctctgcccagaccgctgcatccacagcttccagaacctggggatccagtgt
gtaaagaagcgggacctggagcaggccatcagtcaacgtatccagaccaacaacaatccc
ttccaagttcccatagaagaacagcgtggggactacgacctgaatgcggtgcggctctgc
ttccaggtgacagtgcgggacccggcaggcaggcccctccgcttgccacctgtcctctcg
catcccatctttgacaaccgtgcccccaacaccgccgagctcaagatctgccgagtgaac
cgaaactctgggagctgcctcgggggggatgagatcttcctgctgtgtgacaaggtgcag
aaagaggacattgaagtgtatttcacgggaccaggctgggaggcccgaggctccttttct
caagctgacgtacaccgacaagtggccattgtgttccggacacctccctatgccgacccc
agcctgcaggcccccgtgcgtgtctccatgcagctgcggcggccttcagatcgggagctc
agcgagcccatggaatttcagtacttgccagacacagatgatcgtcaccggattgaggag
aaacgcaaaaggacatacgagaccttcaagagcatcatgaaaaagagtcctttcaatgga
cccaccgacccccggcctccaccccggcgcatcgctgtgccttcccgaagctcagctgcc
gtccccaagccagctccccagccctatccctttacgccatccctcagtaccatcaacttc
gaggagttctcccccatggtcttctcttccgggcagatcccaagccagacccctgccttg
gcaccagcccctgccccaatcctggccccggcccctgcctctgtcccggcccctgccccg
gtccccgccccnnncccggccccggccccggcccctgccccaatcttagccccaggcctt
gctcaggctgtggtcccgcctgctcccaagaccacccaggctggggaagggacgctgacg
gaggccctgctgcagctgcagtttgacgctgatgaagacctgggggccctgcttggcaac
agcgccgacccggcagtgttcacagacctggcatccgtcgacaactctgagtttcagcag
ctgctgaaccagggtgtatctgtggccccccacccagctgagcccatgctgatggaatac
cctgaggcaataactcgcctggtgacgggatcccagaggccccctgacccagctcccgct
cccctgggggcctcggggcttcccaacggcctcctctcaggggatgaagacttctcttcc
attgccgacatggacttctcagcccttctgagtcagatcagctcctaa

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