Panthera pardus (leopard): 109253123 Help Entry 109253123         CDS       T06062                                  Symbol SPHK2 Name (RefSeq) sphingosine kinase 2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism ppad  Panthera pardus (leopard) Pathway ppad00600   Sphingolipid metabolism ppad01100   Metabolic pathways ppad04020   Calcium signaling pathway ppad04071   Sphingolipid signaling pathway ppad04072   Phospholipase D signaling pathway ppad04148   Efferocytosis ppad04370   VEGF signaling pathway ppad04371   Apelin signaling pathway ppad04666   Fc gamma R-mediated phagocytosis ppad05152   Tuberculosis Module ppad_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     109253123 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     109253123 (SPHK2)    04371 Apelin signaling pathway     109253123 (SPHK2)    04020 Calcium signaling pathway     109253123 (SPHK2)    04072 Phospholipase D signaling pathway     109253123 (SPHK2)    04071 Sphingolipid signaling pathway     109253123 (SPHK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     109253123 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     109253123 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     109253123 (SPHK2) Enzymes [BR:ppad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      109253123 (SPHK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  109253123 NCBI-ProteinID:  XP_019281345 Ensembl:  ENSPPRG00000000381 UniProt:  A0A9W2VS95 LinkDB All DBs Position Unknown AA seq 658 aa AA seqDB search MNGHLETEEQGDQRPDQELTWSWGHRPRSALDGAKAMAPPPPPPLAASTPLLHGEFGSFP ARSSRFALTLTPQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDAAAAYFCIY TYPQGRRGGRRRAARTFRVDGAATYEENRAEAQRWATALMCLLRGLPLPGDGEITPELLP KPPRLLLLVNPLGGRGLAWQWCKTHVLPMISEAGLSFNLIQTERQNHARELVQGLRLSEW DGIVTVSGDGLLFEVLNGFLDRPDWEEAVKTPVGILPCGSGNALAGAVNQHGGFEPALGV DLLLNCSLLLCRGGSRPLDLMSVTLASGSRCLSFLSVAWGFVSDVDIQSERFRALGSARF TLGTVLGLATLHTYRGRLSYLPATVEPTSPTPARGLPRAKSELTLAPAPAPAPPVAHSPL HRSVSDLPLPLPQPALTSPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPPLPSPPS SPKAALLSPITEGVPETLASSGLPPPTPGSPGAVSTRGPHDHLLPPLGTPLPPGWVTLEG DFVLMLAISPSHLGADLVAAPHARFDDGLVHLCWVRGGISRAALLRLFLAMERGSHFSLG CPQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGLGTLLTGPPGCPRREP NT seq 1977 nt NT seq  +upstreamnt  +downstreamnt atgaatggacacctcgaaacagaggagcagggggatcagaggccagaccaggagctgacc tggagctggggccacaggcctagaagcgccctggacggggccaaggccatggccccccca ccgccgccaccattggccgccagcaccccgctcctgcatggcgagtttggctccttcccg gcccgcagctcccgcttcgccctcactctcacaccacaggccctacacatacagcggctg cgcccaaagcctgaagcccggccccggggcggcctggtcccgctggccgaggtgtccggc tgctgcaccctgcggagccgcagcccctcggacgcagcagcggcctacttctgcatctac acctatccgcagggccggcgcgggggccggcgcagagccgcccgcacctttcgggtcgac ggggcggccacctacgaggagaaccgcgctgaggcccagcgctgggccactgccctcatg tgtctgctccgtggactgccgctgcctggggacggggaaataacccccgagcttctgcca aagccaccccgattgctcctattggtcaatccccttgggggacggggcctggcctggcag tggtgtaagacccacgtgctgcccatgatctccgaagctgggctgtccttcaacctcatc cagacagaacgacagaaccatgcccgggagctggttcaggggctgaggctgagtgagtgg gacggcattgtcacggtctccggagacgggctgctgtttgaggtgctgaacggattcctg gaccgccctgactgggaagaggctgtgaagacgcccgtgggcatcctcccctgtggctca ggcaatgccttggccggagctgtgaaccagcatggggggtttgaacctgccctgggtgtg gacctgctgctcaattgctcgctgctactctgccggggcggcagccgcccgctggacctg atgtctgtgacgctggcctccggctcccgctgcttgtccttcctgtctgtggcctggggc ttcgtgtcagacgtggatatccagagcgagcgcttcagggccctgggcagtgcccgcttc acactgggcacagtgctgggcctcgccacactgcacacctaccgaggacgcctctcctac ctccctgccaccgtggagcccacctcacccacccctgcccgtggcctgccccgtgccaag tcagagctgaccctggccccggccccggccccggccccacctgtggcacactcacccctg catcgttcagtgtctgacctgcccctgcccctgccccagcccgccctgacctcccctggc tcgcctgaacccctgcccatcctgtccctcaatggcgggggcccagagttggccggggac tggggtggggctggggatgcccccctgtccccagacccaccactgccctcaccgcctagc tcccctaaggcagctttactgtcacccatcaccgagggggtcccagaaacgttggcatcc tctgggcttccccctcccacccccggctctccgggagccgtctctaccaggggcccgcat gaccacctgctccctcctctgggcaccccactccccccaggctgggtgacgctggagggg gactttgtgctcatgctggccatctcacctagccacctgggggcagacctggtggcagct ccccacgcgcgctttgacgacggcctggtgcacctgtgctgggtgcgtggtggcatctcc cgggctgcgctgctacgcctctttctggccatggagcgaggtagccacttcagcctgggc tgtccgcagctgggctacgccgcggcccgtgccttccgcctcgagcctctcacgcctcgg ggcgtgctcactgtggacggagagcaggtggagtacgggccactgcaggcgcagatgcac ccgggcctcggcacgctgctcactgggcctcccggctgcccgcgtcgggagccttga

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