Panthera pardus (leopard): 109272472
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Entry
109272472 CDS
T06062
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01521
EGFR tyrosine kinase inhibitor resistance
ppad01522
Endocrine resistance
ppad04012
ErbB signaling pathway
ppad04015
Rap1 signaling pathway
ppad04062
Chemokine signaling pathway
ppad04137
Mitophagy - animal
ppad04144
Endocytosis
ppad04360
Axon guidance
ppad04370
VEGF signaling pathway
ppad04510
Focal adhesion
ppad04520
Adherens junction
ppad04530
Tight junction
ppad04540
Gap junction
ppad04611
Platelet activation
ppad04613
Neutrophil extracellular trap formation
ppad04625
C-type lectin receptor signaling pathway
ppad04727
GABAergic synapse
ppad04750
Inflammatory mediator regulation of TRP channels
ppad04810
Regulation of actin cytoskeleton
ppad04912
GnRH signaling pathway
ppad04915
Estrogen signaling pathway
ppad04917
Prolactin signaling pathway
ppad04919
Thyroid hormone signaling pathway
ppad04921
Oxytocin signaling pathway
ppad04926
Relaxin signaling pathway
ppad05100
Bacterial invasion of epithelial cells
ppad05135
Yersinia infection
ppad05152
Tuberculosis
ppad05161
Hepatitis B
ppad05163
Human cytomegalovirus infection
ppad05167
Kaposi sarcoma-associated herpesvirus infection
ppad05168
Herpes simplex virus 1 infection
ppad05203
Viral carcinogenesis
ppad05205
Proteoglycans in cancer
ppad05207
Chemical carcinogenesis - receptor activation
ppad05208
Chemical carcinogenesis - reactive oxygen species
ppad05219
Bladder cancer
ppad05417
Lipid and atherosclerosis
ppad05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
109272472 (SRC)
04015 Rap1 signaling pathway
109272472 (SRC)
04370 VEGF signaling pathway
109272472 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
109272472 (SRC)
04137 Mitophagy - animal
109272472 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
109272472 (SRC)
04520 Adherens junction
109272472 (SRC)
04530 Tight junction
109272472 (SRC)
04540 Gap junction
109272472 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109272472 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109272472 (SRC)
04613 Neutrophil extracellular trap formation
109272472 (SRC)
04625 C-type lectin receptor signaling pathway
109272472 (SRC)
04062 Chemokine signaling pathway
109272472 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
109272472 (SRC)
04915 Estrogen signaling pathway
109272472 (SRC)
04917 Prolactin signaling pathway
109272472 (SRC)
04921 Oxytocin signaling pathway
109272472 (SRC)
04926 Relaxin signaling pathway
109272472 (SRC)
04919 Thyroid hormone signaling pathway
109272472 (SRC)
09156 Nervous system
04727 GABAergic synapse
109272472 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
109272472 (SRC)
09158 Development and regeneration
04360 Axon guidance
109272472 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
109272472 (SRC)
05207 Chemical carcinogenesis - receptor activation
109272472 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
109272472 (SRC)
05203 Viral carcinogenesis
109272472 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
109272472 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
109272472 (SRC)
05168 Herpes simplex virus 1 infection
109272472 (SRC)
05163 Human cytomegalovirus infection
109272472 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
109272472 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
109272472 (SRC)
05152 Tuberculosis
109272472 (SRC)
05100 Bacterial invasion of epithelial cells
109272472 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109272472 (SRC)
05418 Fluid shear stress and atherosclerosis
109272472 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109272472 (SRC)
01522 Endocrine resistance
109272472 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109272472 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ppad04131
]
109272472 (SRC)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109272472 (SRC)
Protein kinases [BR:
ppad01001
]
Non-receptor tyrosine kinases
SRC family
109272472 (SRC)
Membrane trafficking [BR:
ppad04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
109272472 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
109272472 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
109272472 (SRC)
Macropinocytosis
Kinases
109272472 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
109272472
NCBI-ProteinID:
XP_019314085
Ensembl:
ENSPPRG00000004596
UniProt:
A0A9W2UI68
LinkDB
All DBs
Position
Unknown
AA seq
553 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgctagccaacggcgccgcagcctggagcct
gctgagaacacccacggtggtggtgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgacggccaccgaggccccagtacggccttcccctctgccgctgctgag
cccaagctgttcgggggcttcaactcctcggacacagtcacctccccgcagagggcgggg
ccactggcaggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
actgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaggtg
gacgtcagccagacctggttcacattcagatggctgcaaagagagggtgactggtggctg
gcccactcactcagcacaggacagacgggctacatccccagcaactatgtggcgccctct
gactctatccaggccgaagagtggtactttggcaagatcaccagacgggagtcagagagg
ttactgctcaatgcggaaaacccaagagggaccttcctagtgcgagaaagcgagaccacg
aaaggcgcctactgcctctccgtgtccgatttcgacaacgccaagggcctcaatgtgaag
cattacaagatccgcaagctggacagcggtggcttctacatcacctcccgcacccagttc
aacagtctgcagcagctggtggcctactactccaaacatgccgacggcctctgccaccgc
ctcaccaccgtgtgccccacgtccaagccacagactcagggcctggccaaagacgcctgg
gagatcccccgggagtccctgcggctggaggtcaagctgggccagggctgtttcggagag
gtgtggatggggacctggaacggaaccaccagggtggccatcaaaaccctgaagccaggc
acaatgtctccagaggcctttctgcaggaggcccaggtcatgaagaaactaaggcacgag
aaattggtgcagctgtatgccgtggtgtctgaggagcccatctacattgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggagacaggcaagtacctgcggctg
ccacagctggtggacatggctgctcagatcgcctcgggcatggcctacgtggagcggatg
aactacgtgcaccgggacctccgtgctgccaacattctggttggagagaacctcgtgtgc
aaagtggccgacttcgggctggctcggctcatcgaagacaatgaatacaccgcccggcaa
ggtgccaaattccccatcaagtggacggctccagaagcggccctgtacggccggttcacc
atcaagtcagatgtgtggtcctttgggatcctgctgacggagctcacaacaaagggacgg
gtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccgcctgagtgtcccgagtccctgcatgacctcatgtgccagtgctggcgg
aaggaaccggaagagcggcccaccttcgagtacctgcaggccttcctagaggactacttc
acgtccaccgagccccagtaccagcctggagagaacctatag
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integrated database retrieval system
