KEGG   Pan paniscus (bonobo): 100968593
Entry
100968593         CDS       T02283                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X2
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04020  Calcium signaling pathway
pps04022  cGMP-PKG signaling pathway
pps04114  Oocyte meiosis
pps04218  Cellular senescence
pps04310  Wnt signaling pathway
pps04360  Axon guidance
pps04370  VEGF signaling pathway
pps04380  Osteoclast differentiation
pps04625  C-type lectin receptor signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps04720  Long-term potentiation
pps04724  Glutamatergic synapse
pps04728  Dopaminergic synapse
pps04921  Oxytocin signaling pathway
pps04922  Glucagon signaling pathway
pps04924  Renin secretion
pps05010  Alzheimer disease
pps05014  Amyotrophic lateral sclerosis
pps05020  Prion disease
pps05022  Pathways of neurodegeneration - multiple diseases
pps05031  Amphetamine addiction
pps05152  Tuberculosis
pps05163  Human cytomegalovirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05170  Human immunodeficiency virus 1 infection
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100968593 (PPP3CB)
   04310 Wnt signaling pathway
    100968593 (PPP3CB)
   04370 VEGF signaling pathway
    100968593 (PPP3CB)
   04020 Calcium signaling pathway
    100968593 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    100968593 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100968593 (PPP3CB)
   04218 Cellular senescence
    100968593 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100968593 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    100968593 (PPP3CB)
   04660 T cell receptor signaling pathway
    100968593 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    100968593 (PPP3CB)
   04659 Th17 cell differentiation
    100968593 (PPP3CB)
   04662 B cell receptor signaling pathway
    100968593 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100968593 (PPP3CB)
   04921 Oxytocin signaling pathway
    100968593 (PPP3CB)
   04924 Renin secretion
    100968593 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100968593 (PPP3CB)
   04728 Dopaminergic synapse
    100968593 (PPP3CB)
   04720 Long-term potentiation
    100968593 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    100968593 (PPP3CB)
   04380 Osteoclast differentiation
    100968593 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100968593 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100968593 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    100968593 (PPP3CB)
   05163 Human cytomegalovirus infection
    100968593 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100968593 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100968593 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100968593 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    100968593 (PPP3CB)
   05020 Prion disease
    100968593 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    100968593 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100968593 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100968593 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pps01009]
    100968593 (PPP3CB)
Enzymes [BR:pps01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100968593 (PPP3CB)
Protein phosphatases and associated proteins [BR:pps01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100968593 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 100968593
NCBI-ProteinID: XP_008967260
Ensembl: ENSPPAG00000004680
LinkDB
Position
10:complement(69984241..70043352)
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHTAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtccctttccccccaacacatcgcttgacatct
gaagaagtatttgatttggatgggatacccagggttgatgttctgaagaaccacttggtg
aaagaaggtcgagtagatgaagaaattgcgcttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaagctccaatcacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggcgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggttctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaagtattcg
gaaagagtctatgaagcttgcatggaagcttttgatagtttgcctcttgctgcactttta
aaccaacagtttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgtta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcctaattttatggatgtcttcacg
tggtctttaccgtttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactaatgactgaaggtgaagaccagtttgatgtaggttcagctgca
gcccggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagagtcttc
tctgttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacaggg
atgttgcctagtggagtgttagctggaggacggcagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccacctcggaaagatgctgta
cagcaagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggacgggc
aaccatactgcccagtga

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