Phodopus roborovskii (desert hamster): 127236205
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Entry
127236205 CDS
T08852
Symbol
Raf1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob01521
EGFR tyrosine kinase inhibitor resistance
prob01522
Endocrine resistance
prob04010
MAPK signaling pathway
prob04012
ErbB signaling pathway
prob04014
Ras signaling pathway
prob04015
Rap1 signaling pathway
prob04022
cGMP-PKG signaling pathway
prob04024
cAMP signaling pathway
prob04062
Chemokine signaling pathway
prob04068
FoxO signaling pathway
prob04071
Sphingolipid signaling pathway
prob04072
Phospholipase D signaling pathway
prob04140
Autophagy - animal
prob04150
mTOR signaling pathway
prob04151
PI3K-Akt signaling pathway
prob04210
Apoptosis
prob04218
Cellular senescence
prob04270
Vascular smooth muscle contraction
prob04360
Axon guidance
prob04370
VEGF signaling pathway
prob04371
Apelin signaling pathway
prob04510
Focal adhesion
prob04540
Gap junction
prob04550
Signaling pathways regulating pluripotency of stem cells
prob04613
Neutrophil extracellular trap formation
prob04625
C-type lectin receptor signaling pathway
prob04630
JAK-STAT signaling pathway
prob04650
Natural killer cell mediated cytotoxicity
prob04660
T cell receptor signaling pathway
prob04662
B cell receptor signaling pathway
prob04664
Fc epsilon RI signaling pathway
prob04666
Fc gamma R-mediated phagocytosis
prob04720
Long-term potentiation
prob04722
Neurotrophin signaling pathway
prob04726
Serotonergic synapse
prob04730
Long-term depression
prob04810
Regulation of actin cytoskeleton
prob04910
Insulin signaling pathway
prob04912
GnRH signaling pathway
prob04914
Progesterone-mediated oocyte maturation
prob04915
Estrogen signaling pathway
prob04916
Melanogenesis
prob04917
Prolactin signaling pathway
prob04919
Thyroid hormone signaling pathway
prob04921
Oxytocin signaling pathway
prob04926
Relaxin signaling pathway
prob04928
Parathyroid hormone synthesis, secretion and action
prob04929
GnRH secretion
prob04935
Growth hormone synthesis, secretion and action
prob05010
Alzheimer disease
prob05022
Pathways of neurodegeneration - multiple diseases
prob05034
Alcoholism
prob05132
Salmonella infection
prob05152
Tuberculosis
prob05160
Hepatitis C
prob05161
Hepatitis B
prob05163
Human cytomegalovirus infection
prob05164
Influenza A
prob05165
Human papillomavirus infection
prob05167
Kaposi sarcoma-associated herpesvirus infection
prob05170
Human immunodeficiency virus 1 infection
prob05200
Pathways in cancer
prob05205
Proteoglycans in cancer
prob05206
MicroRNAs in cancer
prob05207
Chemical carcinogenesis - receptor activation
prob05208
Chemical carcinogenesis - reactive oxygen species
prob05210
Colorectal cancer
prob05211
Renal cell carcinoma
prob05212
Pancreatic cancer
prob05213
Endometrial cancer
prob05214
Glioma
prob05215
Prostate cancer
prob05218
Melanoma
prob05219
Bladder cancer
prob05220
Chronic myeloid leukemia
prob05221
Acute myeloid leukemia
prob05223
Non-small cell lung cancer
prob05224
Breast cancer
prob05225
Hepatocellular carcinoma
prob05226
Gastric cancer
prob05230
Central carbon metabolism in cancer
prob05231
Choline metabolism in cancer
prob05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
127236205 (Raf1)
04012 ErbB signaling pathway
127236205 (Raf1)
04014 Ras signaling pathway
127236205 (Raf1)
04015 Rap1 signaling pathway
127236205 (Raf1)
04370 VEGF signaling pathway
127236205 (Raf1)
04371 Apelin signaling pathway
127236205 (Raf1)
04630 JAK-STAT signaling pathway
127236205 (Raf1)
04068 FoxO signaling pathway
127236205 (Raf1)
04072 Phospholipase D signaling pathway
127236205 (Raf1)
04071 Sphingolipid signaling pathway
127236205 (Raf1)
04024 cAMP signaling pathway
127236205 (Raf1)
04022 cGMP-PKG signaling pathway
127236205 (Raf1)
04151 PI3K-Akt signaling pathway
127236205 (Raf1)
04150 mTOR signaling pathway
127236205 (Raf1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
127236205 (Raf1)
09143 Cell growth and death
04210 Apoptosis
127236205 (Raf1)
04218 Cellular senescence
127236205 (Raf1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
127236205 (Raf1)
04540 Gap junction
127236205 (Raf1)
04550 Signaling pathways regulating pluripotency of stem cells
127236205 (Raf1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
127236205 (Raf1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
127236205 (Raf1)
04625 C-type lectin receptor signaling pathway
127236205 (Raf1)
04650 Natural killer cell mediated cytotoxicity
127236205 (Raf1)
04660 T cell receptor signaling pathway
127236205 (Raf1)
04662 B cell receptor signaling pathway
127236205 (Raf1)
04664 Fc epsilon RI signaling pathway
127236205 (Raf1)
04666 Fc gamma R-mediated phagocytosis
127236205 (Raf1)
04062 Chemokine signaling pathway
127236205 (Raf1)
09152 Endocrine system
04910 Insulin signaling pathway
127236205 (Raf1)
04929 GnRH secretion
127236205 (Raf1)
04912 GnRH signaling pathway
127236205 (Raf1)
04915 Estrogen signaling pathway
127236205 (Raf1)
04914 Progesterone-mediated oocyte maturation
127236205 (Raf1)
04917 Prolactin signaling pathway
127236205 (Raf1)
04921 Oxytocin signaling pathway
127236205 (Raf1)
04926 Relaxin signaling pathway
127236205 (Raf1)
04935 Growth hormone synthesis, secretion and action
127236205 (Raf1)
04919 Thyroid hormone signaling pathway
127236205 (Raf1)
04928 Parathyroid hormone synthesis, secretion and action
127236205 (Raf1)
04916 Melanogenesis
127236205 (Raf1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
127236205 (Raf1)
09156 Nervous system
04726 Serotonergic synapse
127236205 (Raf1)
04720 Long-term potentiation
127236205 (Raf1)
04730 Long-term depression
127236205 (Raf1)
04722 Neurotrophin signaling pathway
127236205 (Raf1)
09158 Development and regeneration
04360 Axon guidance
127236205 (Raf1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127236205 (Raf1)
05206 MicroRNAs in cancer
127236205 (Raf1)
05205 Proteoglycans in cancer
127236205 (Raf1)
05207 Chemical carcinogenesis - receptor activation
127236205 (Raf1)
05208 Chemical carcinogenesis - reactive oxygen species
127236205 (Raf1)
05230 Central carbon metabolism in cancer
127236205 (Raf1)
05231 Choline metabolism in cancer
127236205 (Raf1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
127236205 (Raf1)
09162 Cancer: specific types
05210 Colorectal cancer
127236205 (Raf1)
05212 Pancreatic cancer
127236205 (Raf1)
05225 Hepatocellular carcinoma
127236205 (Raf1)
05226 Gastric cancer
127236205 (Raf1)
05214 Glioma
127236205 (Raf1)
05221 Acute myeloid leukemia
127236205 (Raf1)
05220 Chronic myeloid leukemia
127236205 (Raf1)
05218 Melanoma
127236205 (Raf1)
05211 Renal cell carcinoma
127236205 (Raf1)
05219 Bladder cancer
127236205 (Raf1)
05215 Prostate cancer
127236205 (Raf1)
05213 Endometrial cancer
127236205 (Raf1)
05224 Breast cancer
127236205 (Raf1)
05223 Non-small cell lung cancer
127236205 (Raf1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
127236205 (Raf1)
05161 Hepatitis B
127236205 (Raf1)
05160 Hepatitis C
127236205 (Raf1)
05164 Influenza A
127236205 (Raf1)
05163 Human cytomegalovirus infection
127236205 (Raf1)
05167 Kaposi sarcoma-associated herpesvirus infection
127236205 (Raf1)
05165 Human papillomavirus infection
127236205 (Raf1)
09171 Infectious disease: bacterial
05132 Salmonella infection
127236205 (Raf1)
05152 Tuberculosis
127236205 (Raf1)
09164 Neurodegenerative disease
05010 Alzheimer disease
127236205 (Raf1)
05022 Pathways of neurodegeneration - multiple diseases
127236205 (Raf1)
09165 Substance dependence
05034 Alcoholism
127236205 (Raf1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127236205 (Raf1)
01522 Endocrine resistance
127236205 (Raf1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
prob01001
]
127236205 (Raf1)
Enzymes [BR:
prob01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
127236205 (Raf1)
Protein kinases [BR:
prob01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
127236205 (Raf1)
BRITE hierarchy
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
RA
C1_2
Motif
Other DBs
NCBI-GeneID:
127236205
NCBI-ProteinID:
XP_051059691
LinkDB
All DBs
Position
Unknown
AA seq
668 aa
AA seq
DB search
MEHIQGAWKSISNGFGLKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDSGVPALPSLTIRRMRESVSRMPASSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIENNSLNASPRACSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPGSGTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQLQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggcgcttggaagtcgatcagcaatggttttggactcaaagatgcg
gtgtttgatggctccagctgcatctccccaacaattgttcagcagtttggctatcagcgc
cgggcctcagatgatggcaaactcacggattcttctaagacaagcaacactatccgagtt
ttcttgccaaataagcaaagaacggtggtcaatgtgcggaatggaatgagcttgcacgac
tgccttatgaaagctctcaaggtgagaggtctgcaaccagagtgttgtgcagtgttcaga
cttctccaggagcacaaaggtaagaaagcacgcttagactggaacaccgatgctgcctcc
ctgattggagaagaactgcaagtggattttttggatcacgttccactgacaactcacaac
tttgctcggaaaacgttcctgaagcttgcattctgtgacatctgtcaaaagttcctgcta
aatggatttcggtgtcagacttgtggctacaagtttcacgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacagctcttgctgtttccaaattccact
gttggtgatagtggagtcccagcactaccttctttgacaattcgccggatgcgagagtct
gtttcccggatgcctgctagttcccagcacagatactccacacctcatgccttcactttc
aacacctccagcccttcctctgaaggttccctctcccagaggcagaggtcaacgtccact
cccaatgtccacatggtcagcaccactttgcctgtggacagcaggatgattgagaataac
agcctgaatgcctctcccagggcgtgctccagacggttttgtctgaggggaagagatgca
attcgaagtcacagtgaatcagcctcaccttcagccctgtccagcagccccaacaatctg
agcccaacaggctggtcacagcctaaaacccctgtgccagcacaaagagaacgggcacca
ggatctgggacccaggaaaaaaacaaaattaggcctcgtgggcagagagattcaagctat
tactgggaaatagaagccagtgaggtgatgctgtccactcggattgggtcgggctccttt
ggcactgtgtacaagggcaagtggcatggagatgttgcagtaaagatcctaaaagtggtt
gacccaacaccagagcagcttcaggccttcaggaacgaggtggccgtcttgcgtaaaacc
aggcatgttaatatcctgctgttcatgggatacatgacaaaggacaacctggcgattgtg
acccagtggtgtgaaggcagcagtctctataaacacctacatgtccaggagaccaagttc
caaatgttccagctaattgacattgcccgacagacagctcagggaatggactatttgcat
gcaaagaatatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctc
acagtgaaaattggagattttggtttggcaacagtgaagtcacgctggagtggttctcag
caggttgaacagcccaccggctccgtgctgtggatggccccagaagtaatccgaatgcag
gataacaacccgtttagcttccagtctgatgtctactcctatggcattgtgctgtatgag
ctgatgactggggagcttccctactcgcacatcaacaaccgagatcagatcatcttcatg
gtgggccgtggatatgcttccccagatcttagcaggctctacaagaactgccccaaggca
atgaagagattggtggctgactgtgtgaagaaagtaaaagaagagaggccactgtttccc
cagatcctgtcgtccatcgagctgcttcagcactctctgccgaaaatcaacagaagcgcc
tctgagccctctctacatcgggcggcccacactgaggacatcaacgcttgcacactgacc
acatccccgaggctaccggtcttctag
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integrated database retrieval system