Panthera tigris altaica (Amur tiger): 102950850 Help Entry 102950850         CDS       T02988                                  Symbol RPS6KB2 Name (RefSeq) ribosomal protein S6 kinase B2   KO K04688   ribosomal protein S6 kinase beta [EC:2.7.11.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg01521   EGFR tyrosine kinase inhibitor resistance ptg01522   Endocrine resistance ptg04012   ErbB signaling pathway ptg04066   HIF-1 signaling pathway ptg04140   Autophagy - animal ptg04150   mTOR signaling pathway ptg04151   PI3K-Akt signaling pathway ptg04152   AMPK signaling pathway ptg04211   Longevity regulating pathway ptg04213   Longevity regulating pathway - multiple species ptg04350   TGF-beta signaling pathway ptg04371   Apelin signaling pathway ptg04666   Fc gamma R-mediated phagocytosis ptg04714   Thermogenesis ptg04910   Insulin signaling pathway ptg04931   Insulin resistance ptg05163   Human cytomegalovirus infection ptg05165   Human papillomavirus infection ptg05170   Human immunodeficiency virus 1 infection ptg05200   Pathways in cancer ptg05205   Proteoglycans in cancer ptg05207   Chemical carcinogenesis - receptor activation ptg05210   Colorectal cancer ptg05212   Pancreatic cancer ptg05221   Acute myeloid leukemia ptg05224   Breast cancer ptg05225   Hepatocellular carcinoma ptg05226   Gastric cancer ptg05231   Choline metabolism in cancer ptg05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102950850 (RPS6KB2)    04350 TGF-beta signaling pathway     102950850 (RPS6KB2)    04371 Apelin signaling pathway     102950850 (RPS6KB2)    04066 HIF-1 signaling pathway     102950850 (RPS6KB2)    04151 PI3K-Akt signaling pathway     102950850 (RPS6KB2)    04152 AMPK signaling pathway     102950850 (RPS6KB2)    04150 mTOR signaling pathway     102950850 (RPS6KB2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102950850 (RPS6KB2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     102950850 (RPS6KB2)   09152 Endocrine system    04910 Insulin signaling pathway     102950850 (RPS6KB2)   09149 Aging    04211 Longevity regulating pathway     102950850 (RPS6KB2)    04213 Longevity regulating pathway - multiple species     102950850 (RPS6KB2)   09159 Environmental adaptation    04714 Thermogenesis     102950850 (RPS6KB2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102950850 (RPS6KB2)    05205 Proteoglycans in cancer     102950850 (RPS6KB2)    05207 Chemical carcinogenesis - receptor activation     102950850 (RPS6KB2)    05231 Choline metabolism in cancer     102950850 (RPS6KB2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102950850 (RPS6KB2)   09162 Cancer: specific types    05210 Colorectal cancer     102950850 (RPS6KB2)    05212 Pancreatic cancer     102950850 (RPS6KB2)    05225 Hepatocellular carcinoma     102950850 (RPS6KB2)    05226 Gastric cancer     102950850 (RPS6KB2)    05221 Acute myeloid leukemia     102950850 (RPS6KB2)    05224 Breast cancer     102950850 (RPS6KB2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102950850 (RPS6KB2)    05163 Human cytomegalovirus infection     102950850 (RPS6KB2)    05165 Human papillomavirus infection     102950850 (RPS6KB2)   09167 Endocrine and metabolic disease    04931 Insulin resistance     102950850 (RPS6KB2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102950850 (RPS6KB2)    01522 Endocrine resistance     102950850 (RPS6KB2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ptg01001]     102950850 (RPS6KB2) Enzymes [BR:ptg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      102950850 (RPS6KB2) Protein kinases [BR:ptg01001]  Serine/threonine kinases: AGC group   RSK family [OT]    102950850 (RPS6KB2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7 Motif Other DBs NCBI-GeneID:  102950850 NCBI-ProteinID:  XP_007095416 LinkDB All DBs Position Un AA seq 486 aa AA seqDB search PPPLPGQVVQLEGEGSWYFPWLLPLGFSQDVWPHGELRAAGLEPVGHCEEVELTETSVNL GPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTR AERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAE ITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMA PEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLILPPYLTPDAR DLVHKFLKRNPSQRMGGGPGDAADVQRHPFFRHINWDDLLARRVDPPFRPCLQSEEDVSQ FDIHFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSSKEGFSFQPKLRSPRRLNSS PRTPVSPLKFSPFEGFRPSPGPLEPTESPLPPLLPPPPPPSSSAPLPIRPPSGTKKSKRG RGRPGR NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt ccccctcctctcccgggccaagtagtccagcttgagggggagggctcctggtactttcct tggctcttacccctcggtttctcacaggacgtgtggccccacggagagttgagggcggct ggcctggagcctgtgggacactgcgaggaggtggagttaacggagaccagtgtgaacctg ggccccgagcgcatcgggccccactgctttgagctgctgcgtgtgctgggcaaggggggc tatggcaaggtgttccaagtgcgaaaggtgcagggcaccaatttgggaaaaatatatgcc atgaaagtcctgaggaaggccaaaattgtgcgcaacgccaaggacacagcacacacgcgg gctgaacggaacattctagagtcagtgaagcaccccttcattgtggaactggcctatgcc ttccagactggtggcaaactctacctcatcctcgagtgcctgagtggcggtgagctcttc acgcatctggagcgagagggcatcttcctggaagacacggcctgtttctacctggcagag atcacgctggccctgggccatctgcactcccaaggcatcatctaccgggacctcaaacct gagaacatcatgctcagcagccagggccacatcaaactgacagactttggactctgcaag gagtcgatccatgagggcgccgtcacccacaccttctgtggcaccattgagtacatggcc cctgagattctggtgcgcagtggccacaaccgggcggtggactggtggagcctgggggcc ctgatgtacgacatgctcactggatcgccacccttcactgcggagaaccggaagaaaacc atggacaagatcatcaaagggaagctgatactgcccccctacctcaccccggatgcccgg gacctcgtccacaagtttctgaagcggaatcccagccaacggatgggtggcggcccagga gacgctgctgatgtgcagagacaccccttcttccgacacattaattgggatgacctcctg gctcgccgcgtagacccccctttcaggccttgtctgcagtcagaggaggacgtgagccag tttgacatccacttcacacggcagacgccagtggacagtccagatgatacggccctcagt gagagcgccaaccaggccttcctgggcttcacgtacgtggcaccctccgtcctggacagc agcaaggagggcttctccttccagcccaagctacgctcccccaggcgcctgaacagcagc ccccggaccccggtcagccccctgaaattctcaccctttgagggattccggcccagccct ggcccattggagcccacggagtcccctctacctcctctcctgccaccaccaccgccaccc tcgagctctgcccccctccccatccgacccccctcggggaccaagaagtctaagaggggc cgtgggcgccctgggcgctag

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