Panthera tigris altaica (Amur tiger): 102962124
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Entry
102962124 CDS
T02988
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00020
Citrate cycle (TCA cycle)
ptg00480
Glutathione metabolism
ptg01100
Metabolic pathways
ptg01200
Carbon metabolism
ptg01210
2-Oxocarboxylic acid metabolism
ptg01230
Biosynthesis of amino acids
ptg04146
Peroxisome
ptg05230
Central carbon metabolism in cancer
Module
ptg_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ptg_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102962124 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102962124 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
102962124 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102962124 (IDH2)
Enzymes [BR:
ptg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
102962124 (IDH2)
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Ortholog
Paralog
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
102962124
NCBI-ProteinID:
XP_007078286
UniProt:
A0A8C9JDF8
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All DBs
Position
Un
AA seq
407 aa
AA seq
DB search
MDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTVDSALATQKYSVAVK
CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR
HAHGDQYKATDFVVDRAGTFKIVFSPKDGSGAKEWEVFNFPAGGVGMGMYNTDESISGFA
HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDD
MVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVT
RHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMT
KDLAGCIHGLSNVKLNEHFLNTSDFLDTGWGGSGPRLSLPAPLRRPL
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atggacggcgatgagatgacccggatcatctggcagttcatcaaggagaagctcatcctg
ccgcacgtggatgtccagctcaagtatttcgacctggggctcccaaaccgtgaccagacc
aacgaccaggtcaccgtagactccgcactggccacccagaagtacagtgtggctgtgaag
tgcgccaccatcacccccgatgaggcccgtgtggaagaattcaagctgaagaagatgtgg
aagagtcccaatggaaccatccgaaacatccttggggggaccgtcttccgggaacccatc
atctgcaaaaacatcccacgcctcgtccccggctggaccaagcccatcaccattggcagg
cacgcccatggcgaccagtacaaggccacagactttgtggtcgaccgggccggcacgttc
aagatcgtcttctccccgaaggatggcagtggcgctaaggagtgggaagtgttcaatttc
cctgccggcggcgtggggatgggcatgtacaacacggatgagtccatctcgggttttgcg
cacagctgcttccagtacgccatccagaagaagtggccgctgtacatgagcaccaagaac
accatcctgaaagcctacgacgggcgcttcaaggacatcttccaggaaatctttgacaag
cactataagaccgacttcgacaagaataagatctggtacgagcaccggctcatcgatgac
atggtggctcaggtcctcaagtcttcaggcggcttcgtgtgggcctgcaagaactacgac
ggagatgtgcagtcggacatcctggcccagggctttggctccctcggcctgatgacgtct
gtgctggtctgcccagatgggaagaccatcgaggctgaggccgctcacgggacggtcacc
cgccattatagggagcaccagaagggccggcctaccagcaccaaccccatcgccagcatc
tttgcctggacgcgtggcctggagcaccgggggaagctggatgggaaccaggacctcatc
aggtttgcacagaccctggagaaggtgtgtgtccagacggtggagagcggagccatgacc
aaggacctggcgggctgcatccatggcctcagcaacgtgaagctgaacgagcacttcctg
aacacctcggacttcctggacacggggtgggggggcagcgggccgcggctgagcctcccg
gcccctctcaggaggcctttgtag
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