Panthera tigris altaica (Amur tiger): 102962533 Help Entry 102962533         CDS       T02988                                  Symbol HK2 Name (RefSeq) hexokinase 2   KO K00844   hexokinase [EC:2.7.1.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00010   Glycolysis / Gluconeogenesis ptg00051   Fructose and mannose metabolism ptg00052   Galactose metabolism ptg00500   Starch and sucrose metabolism ptg00520   Amino sugar and nucleotide sugar metabolism ptg00524   Neomycin, kanamycin and gentamicin biosynthesis ptg01100   Metabolic pathways ptg01200   Carbon metabolism ptg01250   Biosynthesis of nucleotide sugars ptg04066   HIF-1 signaling pathway ptg04910   Insulin signaling pathway ptg04930   Type II diabetes mellitus ptg04973   Carbohydrate digestion and absorption ptg05230   Central carbon metabolism in cancer Module ptg_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ptg_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose ptg_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102962533 (HK2)    00051 Fructose and mannose metabolism     102962533 (HK2)    00052 Galactose metabolism     102962533 (HK2)    00500 Starch and sucrose metabolism     102962533 (HK2)    00520 Amino sugar and nucleotide sugar metabolism     102962533 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     102962533 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     102962533 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102962533 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     102962533 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     102962533 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102962533 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ptg04131]     102962533 (HK2) Enzymes [BR:ptg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      102962533 (HK2) Membrane trafficking [BR:ptg04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     102962533 (HK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  102962533 NCBI-ProteinID:  XP_015393508 LinkDB All DBs Position Un AA seq 928 aa AA seqDB search MAAVELWPVHLCSFVYMTSPSEVVAMQPLNKAVDQYLYHMRLSDENLLEISQRFRKEMEK GLGATTHPTASVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMEN QIYAIPEDLMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLV SWTKGFKSSGVEGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLI VGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGTLDDFRTEFDQEIDMGSLNPG KQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPGLLATGHFETKDVSDIEGEKDGI RKAREVLVRLGIDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRST IGVDGSVYKKHPHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRA RQNTLESLKLNREQLLEVKKRMKVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFL ALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYM GMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDL DVVAVVNDTVGTMMTCGYEDPHCEIGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEW GAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFR GRISERLKTRGIFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARR AAQLCGAGMAAVVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVS FLESEDGSGKGAALITAVACRIREAGQR NT seq 2787 nt NT seq  +upstreamnt  +downstreamnt atggctgctgtagaactgtggccagtccacctttgctctttcgtgtacatgacctcgccc tccgaggtcgtggccatgcagcctcttaataaagcagtggaccagtatctctaccacatg cgtctttctgatgagaaccttctggagatctctcagcggttccgcaaggagatggagaaa gggcttggagccaccacccaccccactgcttcagtgaaaatgctgcccacctttgtgagg tctactccagatgggacagaacatggagagtttctggctctggaccttggggggaccaac ttccgtgtgcttcgtgtaagagtaacagacaatgggctccagaaggtcgagatggagaac cagatctatgccatccctgaggacctcatgcgaggcagcggcacccagctgtttgaccac attgctgaatgcctggctaacttcatggataagctacaaatcaaagacaagaagctcccc ttgggttttactttctcattcccctgtgtccaaacgaagctagatgagagtttcctggtc tcctggaccaaggggttcaagtccagtggcgtggaaggcaaagacgtggttactctgatc cggaaggccatccagaggagaggggactttgatattgatattgtggccgtggtgaatgac acagttgggaccatgatgacctgtggttatgatgaccagaattgtgagattggtctcatt gtgggcacgggcagcaatgcctgctacatggaagagatgcgccacattgacatggtggag ggcgacgaggggcggatgtgtatcaacatggagtggggggcctttggggacgacggcaca cttgatgacttccgcactgagtttgatcaggagatcgacatgggctccctgaaccctggg aaacaactatttgagaagatgatcagtgggatgtatatgggtgaactggtaagacttatc ctggtgaagatggccaaggaggagctgctttttggggggaagctcagcccagggctcctc gccactggccactttgagaccaaagacgtttcagatattgaaggggagaaggacggcatc cggaaggcccgtgaggtgctagtgcggctgggcatagacccgacgcaggaggactgcgtg gccactcaccgggtgtgccagatcgtgtccacacgctcagccagcctgtgtgcagccacc ctggcagctgtgctgcggcgcatcaaggagaacaagggcgaggagaggctgcgctccacc attggggttgatggttctgtctacaagaagcaccctcatttcgccaagcgtcttcacaag acggttcggcgcctggtgcctgactgcgacgtccgtttcctgcgttccgaggatggcagt ggcaagggggcagccatggtgacggcagtggcctaccggctggctgaccaacacagagcc cgccagaataccctggagtctctgaagctgaaccgtgagcagctgctggaggttaagaag aggatgaaggtagaaatggagcgaggtctgagcaaggagacccacgccattgcccccgtc aagatgctgcccacctacgtgtgtgccacccctgatggcacagagaaaggtgacttcctg gccttggaccttgggggtaccaatttccgggtcctgctggtgcgtgtgaggaatgggaag aggcgcggagtggagatgcacaacaagatctactctatcccacaggaggtcatgcatggc acaggggatgagctctttgaccacatcgtccagtgcatcgccgacttccttgagtacatg ggcatgaagggcgtgtccctgcctctgggtttcaccttctccttcccctgccagcagaac agcctggatgagagcatcctcctcaagtggactaaaggcttcaaggcatcgggctgcgag ggagaggatgtggtcaccctgctgaaggaagccattcaccggcgagaggagtttgacctg gatgtggtcgccgtggtgaatgacacagttgggacgatgatgacctgtggctatgaagac cctcactgtgaaatcggcctcattgttggcacgggcagcaacgcctgctacatggaggag atgcggaacgtggagctggtggaaggggaggagggccggatgtgtgtcaacatggagtgg ggggccttcggggacaacgggtgcctggacgacttccgcacggaatttgatgtggctgtg gatgagctttctctcaaccctggcaaacagaggtttgagaaaatgatcagtggcatgtat ttgggcgagattgtccgtaacatcctcatcgatttcaccaagcgtgggctgctcttccgt ggccgcatctcagaacgactcaagacaagaggaatctttgaaactaagttcctgtctcag attgagagtgactgcctagccctgctgcaggtccgcgccatcctgcaccacctggggctc gagagcacctgtgacgacagcatcatcgtcaaagaggtgtgcacggtggtggcacggcgg gcggcccagctctgtggtgcgggcatggccgccgtggtggacaaaatacgagaaaaccgt gggctggacaccctcaaagtgacagtaggcgtggatgggaccctctacaagctacatcct cactttgccaaagtcatgcatgagacggtgaaagacctggctccgaaatgtgatgtgtcc ttcctggagtcagaggatggcagcgggaagggggcagctctcatcactgctgtggcctgc cgcatccgtgaggctggacagcgatag

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