KEGG   Panthera tigris altaica (Amur tiger): 102971089
Entry
102971089         CDS       T02988                                 
Symbol
MGST3
Name
(RefSeq) microsomal glutathione S-transferase 3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg00480  Glutathione metabolism
ptg00980  Metabolism of xenobiotics by cytochrome P450
ptg00982  Drug metabolism - cytochrome P450
ptg00983  Drug metabolism - other enzymes
ptg01100  Metabolic pathways
ptg01524  Platinum drug resistance
ptg05200  Pathways in cancer
ptg05204  Chemical carcinogenesis - DNA adducts
ptg05207  Chemical carcinogenesis - receptor activation
ptg05208  Chemical carcinogenesis - reactive oxygen species
ptg05225  Hepatocellular carcinoma
ptg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    102971089 (MGST3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    102971089 (MGST3)
   00982 Drug metabolism - cytochrome P450
    102971089 (MGST3)
   00983 Drug metabolism - other enzymes
    102971089 (MGST3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102971089 (MGST3)
   05204 Chemical carcinogenesis - DNA adducts
    102971089 (MGST3)
   05207 Chemical carcinogenesis - receptor activation
    102971089 (MGST3)
   05208 Chemical carcinogenesis - reactive oxygen species
    102971089 (MGST3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    102971089 (MGST3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    102971089 (MGST3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    102971089 (MGST3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptg02000]
    102971089 (MGST3)
Enzymes [BR:ptg01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     102971089 (MGST3)
Transporters [BR:ptg02000]
 Other transporters
  Pores ion channels [TC:1]
   102971089 (MGST3)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 102971089
NCBI-ProteinID: XP_007078171
UniProt: A0A8C9KT49
LinkDB
Position
Un
AA seq 152 aa
MAVLSKEYGFVVLTGAASFIMVAHLAINVSKARKKYKVEYPTMYSTDPENGHLFNCIQRA
HQNTLEVYPPFLFFLAVGGVYHPRVASGLGLAWIVGRVLYAYGYYTGEPSKRSRGAIGSI
ALLGLLGTTVCSAFQHLGWVKTGLGGGSKCCH
NT seq 459 nt   +upstreamnt  +downstreamnt
atggccgtcctctctaaggagtatggttttgtggttctgaccggcgccgccagctttatc
atggtagctcacctggccatcaacgtttccaaggcccgaaagaagtacaaagtggagtat
ccaaccatgtacagcacggaccctgaaaacgggcaccttttcaactgcattcagcgcgcc
caccagaacacgttggaagtgtatcctcctttcttatttttcctagctgttggaggtgtt
taccacccgcgtgtagcttccggcttgggcttggcctggatcgtgggacgagttctctac
gcgtatggttattacacaggagaacccagcaagcggagtcggggcgccatcggctccata
gccctccttggcctgctgggcacaaccgtgtgttctgccttccagcatcttggttgggtt
aaaaccggcttgggcggggggtccaaatgctgccattga

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