Pan troglodytes (chimpanzee): 464586
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Entry
464586 CDS
T01005
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04064
NF-kappa B signaling pathway
ptr04072
Phospholipase D signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr04380
Osteoclast differentiation
ptr04611
Platelet activation
ptr04613
Neutrophil extracellular trap formation
ptr04625
C-type lectin receptor signaling pathway
ptr04650
Natural killer cell mediated cytotoxicity
ptr04662
B cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04666
Fc gamma R-mediated phagocytosis
ptr05152
Tuberculosis
ptr05167
Kaposi sarcoma-associated herpesvirus infection
ptr05168
Herpes simplex virus 1 infection
ptr05169
Epstein-Barr virus infection
ptr05171
Coronavirus disease - COVID-19
ptr05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
464586 (SYK)
04072 Phospholipase D signaling pathway
464586 (SYK)
04151 PI3K-Akt signaling pathway
464586 (SYK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
464586 (SYK)
04613 Neutrophil extracellular trap formation
464586 (SYK)
04625 C-type lectin receptor signaling pathway
464586 (SYK)
04650 Natural killer cell mediated cytotoxicity
464586 (SYK)
04662 B cell receptor signaling pathway
464586 (SYK)
04664 Fc epsilon RI signaling pathway
464586 (SYK)
04666 Fc gamma R-mediated phagocytosis
464586 (SYK)
09158 Development and regeneration
04380 Osteoclast differentiation
464586 (SYK)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
464586 (SYK)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
464586 (SYK)
05168 Herpes simplex virus 1 infection
464586 (SYK)
05167 Kaposi sarcoma-associated herpesvirus infection
464586 (SYK)
05169 Epstein-Barr virus infection
464586 (SYK)
09171 Infectious disease: bacterial
05152 Tuberculosis
464586 (SYK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
464586 (SYK)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
464586 (SYK)
Protein kinases [BR:
ptr01001
]
Non-receptor tyrosine kinases
SYK family
464586 (SYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
464586
NCBI-ProteinID:
XP_016816608
Ensembl:
ENSPTRG00000021098
VGNC:
13975
UniProt:
A0A6D2XLW6
A0A2J8KTF6
LinkDB
All DBs
Position
9:62961924..63059101
Genome browser
AA seq
635 aa
AA seq
DB search
MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGKK
AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
PGHRKSSPAQGNRQESTVSFNPYEPELAPWAAEKGPQREALPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
atggccagcagcggcatggctgacagcgccaaccacctgcccttctttttcggcaacatc
acccgggaggaggcagaagattacctggtccaggggggcatgagtgatgggctttatttg
ctgcgccagagccgcaactacctgggcggcttcgccctgtccgtggcccacgggaagaag
gcacaccactacaccatcgagcgggagctgaatggcacctacgccatcgctggtggcagg
acccatgccagccctgccgacctctgccactaccactcccaggagtctgatggcctggtc
tgcctcctcaagaagcccttcaaccggccccaaggggtgcagcccaagactgggcccttt
gaggatttgaaggaaaacctcatcagggaatatgtgaagcagacatggaacctgcagggt
caggctctggagcaggccatcatcagtcagaagcctcagctggagaagctgatcgctacc
acagcccatgaaaaaatgccttggttccatggaaaaatctctcgggaagaatctgagcaa
attgtcctgataggatcaaagacaaatggaaagttcctgatccgagccagagacaacaat
ggctcctacgccctgtgcctgctgcacgaagggaaggtgctgcactatcgcatcgacaaa
gacaagacagggaagctctccatccccgagggaaagaagttcgacacgctctggcagcta
gtcgagcattattcttataaagcagatggtttgttaagagttcttactgtcccatgtcaa
aaaatcggcacacagggaaatgttaattttggaggccgtccacaacttccaggttcccat
cctgcgacttggtcagcgggtggaataatctcaagaatcaaatcatactccttcccaaag
cctggccacagaaagtcctcccctgcccaagggaaccggcaagagagtactgtgtcattc
aatccgtatgagccagaacttgcaccctgggctgcagaaaaaggcccccagagggaagcc
ctacccatggacacagaggtgtacgagagcccctacgcggaccccgaggagatcaggccc
aaggaggtttacctggaccgaaagctgctgacgctggaagacaaagaactgggctctggt
aattttggaactgtgaaaaagggctactaccaaatgaaaaaagttgtgaaaaccgtggct
gtgaaaatactgaaaaacgaggccaatgaccccgctcttaaagatgagttattagcagaa
gcaaatgtcatgcagcagctggacaacccgtacatcgtgcgcatgattgggatatgcgag
gccgagtcctggatgctggttatggagatggcagaacttggtcccctcaataagtatttg
cagcagaacagacatgtcaaggataagaacatcatagaactggttcatcaggtttccatg
ggcatgaagtacttggaggagagcaattttgtgcacagagatctggctgcaagaaatgtg
ttgctagttacccaacattacgccaagatcagtgatttcggactttccaaagcactgcgt
gctgatgaaaactactacaaggcccagacccatggaaagtggcctgtcaagtggtacgct
ccagaatgcatcaactactacaagttctccagcaaaagcgatgtctggagctttggagtg
ttgatgtgggaagcattctcctatgggcagaagccatatcgagggatgaaaggaagtgaa
gtcaccgctatgttagagaaaggagagcggatggggtgccctgcagggtgtccaagagag
atgtacgatctcatgaatctgtgctggacatacgatgtggaaaacaggcccggattcgca
gcagtggaactgcggctgcgcaattactactatgacgtggtgaactaa
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