Pan troglodytes (chimpanzee): 741291 Help Entry 741291            CDS       T01005                                  Symbol HK2 Name (RefSeq) hexokinase-2 isoform X2   KO K00844   hexokinase [EC:2.7.1.1] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr00010   Glycolysis / Gluconeogenesis ptr00051   Fructose and mannose metabolism ptr00052   Galactose metabolism ptr00500   Starch and sucrose metabolism ptr00520   Amino sugar and nucleotide sugar metabolism ptr00524   Neomycin, kanamycin and gentamicin biosynthesis ptr01100   Metabolic pathways ptr01200   Carbon metabolism ptr01250   Biosynthesis of nucleotide sugars ptr04066   HIF-1 signaling pathway ptr04910   Insulin signaling pathway ptr04930   Type II diabetes mellitus ptr04973   Carbohydrate digestion and absorption ptr05230   Central carbon metabolism in cancer Module ptr_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ptr_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose ptr_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:ptr00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     741291 (HK2)    00051 Fructose and mannose metabolism     741291 (HK2)    00052 Galactose metabolism     741291 (HK2)    00500 Starch and sucrose metabolism     741291 (HK2)    00520 Amino sugar and nucleotide sugar metabolism     741291 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     741291 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     741291 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     741291 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     741291 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     741291 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     741291 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ptr04131]     741291 (HK2) Enzymes [BR:ptr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      741291 (HK2) Membrane trafficking [BR:ptr04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     741291 (HK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N PMT_C3 CCDC66 Motif Other DBs NCBI-GeneID:  741291 NCBI-ProteinID:  XP_001162535 Ensembl:  ENSPTRG00000012104 VGNC:  265 UniProt:  H2QI73 LinkDB All DBs Position 2A:74984133..75044954 Genome browser AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAA VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLG LDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLS HDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKWGGVEMHNKIYAVPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgattgcctcgcatctgcttgcctacttcttcacggagctcaaccatgaccaagtacag aaggttgaccagtatctctaccacatgcgcctctctgatgagaccctcttggagatctct aagcggttccgcaaggagatggagaaagggcttggagccaccactcaccctactgcagca gtgaagatgctgcccacctttgtgaggtccactccagatgggacagaacacggagagttc ctggctctggatcttggagggaccaacttccgtgtgctttgggtgaaagtaacggacaat gggctccagaaggtggagatggagaatcagatctatgccatccctgaggacatcatgcga ggcagtggcacccagctgtttgaccacattgccgaatgcctggctaacttcatggataag ctacaaatcaaagacaagaagctcccactgggttttactttctcgttcccctgccaccag actaaactagacgagagtttcctggtctcatggaccaagggattcaagtccagtggagtg gaaggcagagacgttgtggctctgatccggaaggccatccagaggagaggggactttgat atcgacattgtggctgtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccacaactgtgagattggtctcattgtgggcacgggcagcaacgcctgctacatggaa gagatgcgccacatcgacatggtggaaggcgacgagggacggatgtgtatcaatatggag tggggggcctttggggacgatggctcgctcaacgacattcgcactgagtttgaccaggag attgacatgggctcactgaacccgggaaagcaactgtttgagaagatgatcagtgggatg tacatgggggagctggtgaggcttatcctggtgaagatggccaaggaggagctgctcttt ggggggaagctcagcccagagcttctcaacaccggtcgctttgagaccaaagacatctca gacattgaaggggagaaggatggcatccggaaggcccgtgaggtcctgatgcggttgggc ctggacccgactcaggaggactgcgtggccactcaccggatctgccagatcgtgtccaca cgctccgccagcctgtgcgcagccaccctggccgccgtgctgcagcgcatcaaggagaac aaaggcgaggagcggctgcgctctactattggggtcgacggctccgtctacaagaaacac ccccattttgccaagcgtctacataagaccgtgcggcggctggtgcccggctgcgatgtc cgcttcctccgctccgaggatggcagtggcaaaggtgcagccatggtgacagcagtggct taccggctggccgatcaacaccgtgcccgccagaagacattagagcatctgcagctgagc catgaccagctgctggaggtcaagaggaggatgaaggtagaaatggagcgaggtctgagc aaggagactcacgccagtgcccccgtcaagatgctgcccacctacgtgtgtgctaccccg gacggcacagagaaaggggacttcttggccttggaccttggaggaacaaatttccgggtc ctgctggtccgtgttcggaatgggaagtggggtggagtggagatgcacaacaagatctac gccgtccctcaggaggtcatgcacggcaccggcgacgagctctttgaccacattgtccag tgcatcgcggacttcctcgagtacatgggcatgaagggcgtttccctgcctctgggtttt accttctccttcccctgccagcagaacagcctggacgagagcatcctcctcaagtggaca aaaggcttcaaggcatctggctgcgagggcgaggacgtggtgaccctgctgaaggaagcg atccaccggcgagaggagtttgacctggatgtggttgctgtggtgaacgacacagtcgga actatgatgacctgtggctttgaagaccctcactgtgaagttggcctcattgttggcacg ggcagcaatgcctgctacatggaggagatgcgcaatgtggaactggtggaaggagaagag gggcggatgtgtgtgaacatggaatggggggccttcggggacaatggatgcctagatgac ttccgcacagaatttgatgtggctgtggatgagctttcactcaaccccggcaagcagagg ttcgagaaaatgatcagtggaatgtacctgggtgagattgtccgtaacattctcatcgat ttcaccaagcgtggactgctcttccgaggccgcatctcagagcggctcaagacaaggggc atctttgaaaccaagttcttgtctcagattgagagtgactgcctggccctgctgcaagtc cgagccatcctgcaacacttagggcttgagagcacctgtgacgacagcatcattgttaag gaggtgtgcactgtggtggcccggcgggcagcccagctctgtggcgcaggcatggccgct gtggtggacaagatacgagaaaaccgtgggctggacgctctcaaagtgacagtgggtgtg gatgggaccctctacaagctacatcctcactttgccaaagtcatgcatgagacagtgaag gacctggctccgaaatgtgatgtgtctttcctgcagtcagaggatggcagcgggaagggg gcggcgctcatcactgctgtggcctgccgcatccgtgaggctggacagcgatag

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