Panthera uncia (snow leopard): 125925194
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Entry
125925194 CDS
T08832
Name
(RefSeq) tyrosine-protein kinase ABL2 isoform X1
KO
K08887
abelson tyrosine-protein kinase 2 [EC:
2.7.10.2
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc04012
ErbB signaling pathway
puc04014
Ras signaling pathway
puc05208
Chemical carcinogenesis - reactive oxygen species
puc05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
125925194
04014 Ras signaling pathway
125925194
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
125925194
09166 Cardiovascular disease
05416 Viral myocarditis
125925194
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125925194
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
125925194
Protein kinases [BR:
puc01001
]
Non-receptor tyrosine kinases
ABL family
125925194
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
SH3_3
Haspin_kinase
SH3_6
RGS12_us1
ABC1
Motif
Other DBs
NCBI-GeneID:
125925194
NCBI-ProteinID:
XP_049489993
LinkDB
All DBs
Position
F1:complement(20141178..20246357)
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AA seq
1182 aa
AA seq
DB search
MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDLAGRTTEAGFNIFTQHDHFASCVE
DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA
SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR
SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFST
LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG
EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV
TEYMPYGNLLDYLRECNRDEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN
HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT
YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE
TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGTQDATE
NSASSSAPGFVRGAQAPSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR
NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG
SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR
SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEEG
AAPSRERPKAKLLPRGATALPLRTPSGDPAITEKDSPGVGVAGVAAAPKSKERNGGARLG
MAGVPEDGEQTGWSSPAKAAAALPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL
LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSVCSDPTEEPTAPAAGQPTSETPE
GGKKAAPGAVPVSGKAGRPAMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS
ADKISKEALLECADLLSSAITEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV
SKLELSLQELQVSSAAAGVPGANPVLNNLLSCVQEISDVVQR
NT seq
3549 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcaggtgggccgcgtcggggaggctccggggcttcagcagccgcagcctcgc
gggatccggggcagcagtgcagccaggccctccggccgcaggcgggacctggcggggcgc
accaccgaggccggcttcaatatcttcacccagcatgatcactttgccagctgtgtggag
gatggctttgagggagacaagactggaggcagtagtccagaagccttgcaccgcccctat
ggttgtgacgttgaaccccaggcactgaatgaagccatcaggtggagctccaaggagaat
ttacttggagctactgagagtgaccctaatctctttgttgcactttatgattttgtggcg
agtggtgataatacactcagcatcactaaaggtgaaaagcttcgagtccttggttacaac
cagaatggtgagtggagtgaagttcgctctaagaatggccaaggttgggtgccaagcaac
tacatcaccccagtgaacagcttggaaaaacactcctggtaccatgggcccgtgtcgcgc
agcgctgcggagtacctgctcagcagtctgatcaatggcagcttcctggtgcgggagagt
gagagcagccctgggcagctgtccatctcgctcaggtacgagggccgtgtgtatcactac
aggatcaacaccaccacagacagcaaggtgtatgtaactgccgagagccgctttagcacc
ctggcagagctggttcatcatcactccacagtggcggatgggctggtgacaacattacat
tacccagcgcccaagtgcaataagccaacagtctatggcgtgtcccccatccatgacaaa
tgggaaatggaacgaacagatattaccatgaagcacaaacttgggggtgggcagtatgga
gaagtttatgtcggcgtctggaagaaatatagccttacggttgctgtgaaaacattgaag
gaagataccatggaggtggaagagttcctgaaagaagctgcagtgatgaaggagatcaag
caccctaatctggtacagctattaggtgtgtgtactttggagccaccattttacatcgtg
actgagtacatgccctacggcaacttgcttgattatctccgagagtgcaaccgagacgaa
gtgactgctgtcgtactgctctatatggccactcagatctcttctgcaatggagtattta
gagaagaagaatttcatccatagagatcttgcagcccgtaactgcctagtgggagaaaac
catgtggtaaaagtggctgactttggcttgagtagactgatgactggagacacctatact
gctcatgcgggagccaaatttcctattaaatggacagcaccagagagtcttgcctacaat
accttctcaattaaatctgacgtttgggcttttggggtactgctgtgggaaattgctacg
tatggaatgtcaccatatccaggtattgacctgtctcaggtctatgatctactggaaaaa
ggatatcgaatggaacaacctgaaggatgcccccctaaggtttatgaacttatgagagca
tgctggaagtggagccctgccgacaggccgtcttttgctgaaacacatcaggcttttgaa
accatgttccatgactccagcatttctgaagaggtagctgaggagcttgggagggctgcc
tcctcctcgtctgttgttccatacctgccccgactgcctatacttccttctaagacccga
acgctgaagaaacaggtggagaacaaggagaatatcgaagggacacaggatgccacagaa
aattctgcctccagttcagcaccagggttcgttagaggtgcacaggcccccagtgggtcc
ccagcactgcctcgaaaacaaagagacaagtcacccagcagcctcttggaagatgccaaa
gagacatgcttcaccagggataggaagggaggcttcttcagctccttcatgaaaaagaga
aacgctcccacaccccctaaacgcagcagctccttccgagaaatggagaatcagccccac
aagaaatatgaactcacgggtaacttctcatctgttgcttctctacagcatgctgatggg
ttctctttcactcctgcccagcaagaggcgaatctggtgccacccaagtgctatgggggg
agctttgcacagaggaacctgtgtaatgacgatggcggtgggggcgggggcagcggcact
gctgggggtgggtggtctggcatcacaggcttctttacaccacgcttaatcaaaaagaca
ctgggcttacgagcgggtaaacccacagccagtgatgacacttccaagccttttccaagg
tcaaactctacatcttccatgtcctcagggcttccagagcaggataggatggcaatgacc
cttcccaggaactgccagaggtccaaactccagctggaaaggacagtgtccacctcttct
cagccagaagagaatgtggacagggccaatgacatgcttccaaaaaaatcagaggaaggt
gctgctccaagcagggagagaccaaaagccaaacttttgcctagaggagccacagctctt
cctctcagaaccccctctggggatccagccattacagagaaggactctccgggggtaggg
gtggctggagtggcagctgccccaaagagcaaggagaggaatggcggagcacgacttggc
atggctggagtcccagaggatggcgagcagacaggctggtcttccccggccaaggctgca
gcagccctcccgaccactcacaaccacaaagtgccagtcctcatatcacccactctgaag
cacactccagctgacgtgcagctcattggcacagactctcagggcaataaattcaaactc
ttatctgagcatcaggtcacatcctctggagacaaggaccgaccccgacgggtaaaacca
aagtgtgccccacccccaccacccgtgatgagactactgcagcatccgtccgtgtgctca
gaccccacggaagagccgaccgcccccgctgcaggacagcccacgtcagagacaccggaa
ggagggaagaaggcagctccaggggcagtgcccgtcagtgggaaagctgggaggccagcg
atgcctccgcctcaagtgcctctgcccacctcttccatctcgccggccaaaatggctaat
ggcacagcaggtactaaagtggctctgagaaaaaccaaacaggcggctgagaaaatctca
gcagacaaaatcagcaaggaggccctgctggaatgtgctgacctactgtccagtgcaatc
acggaacccgtgcccaacagccagctggtggacaccggacaccagctgctcgactactgc
tcaggctatgtggactgcatcccccagactcgcaacaaattcgccttccgagaggctgtg
agcaaactggaactcagcctgcaggagctgcaggtgtcttcagcagctgctggtgtgccc
ggggcaaaccctgtccttaataacttattgtcatgtgtacaggagatcagtgatgtggtg
cagaggtag
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