Pteropus vampyrus (large flying fox): 105296612 Help Entry 105296612         CDS       T07815                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp04062   Chemokine signaling pathway pvp04151   PI3K-Akt signaling pathway pvp04217   Necroptosis pvp04550   Signaling pathways regulating pluripotency of stem cells pvp04630   JAK-STAT signaling pathway pvp04658   Th1 and Th2 cell differentiation pvp04659   Th17 cell differentiation pvp05161   Hepatitis B pvp05162   Measles pvp05166   Human T-cell leukemia virus 1 infection pvp05169   Epstein-Barr virus infection pvp05200   Pathways in cancer pvp05203   Viral carcinogenesis pvp05223   Non-small cell lung cancer pvp05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:pvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105296612 (JAK3)    04151 PI3K-Akt signaling pathway     105296612 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105296612 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105296612 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     105296612 (JAK3)    04659 Th17 cell differentiation     105296612 (JAK3)    04062 Chemokine signaling pathway     105296612 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105296612 (JAK3)    05203 Viral carcinogenesis     105296612 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     105296612 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105296612 (JAK3)    05161 Hepatitis B     105296612 (JAK3)    05162 Measles     105296612 (JAK3)    05169 Epstein-Barr virus infection     105296612 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     105296612 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pvp01001]     105296612 (JAK3) Enzymes [BR:pvp01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105296612 (JAK3) Protein kinases [BR:pvp01001]  Non-receptor tyrosine kinases   JAK family [OT]    105296612 (JAK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl Kdo FERM_C_FAK1 ABC1 Haspin_kinase Motif Other DBs NCBI-GeneID:  105296612 NCBI-ProteinID:  XP_011365121 UniProt:  A0A6P6CTQ5 LinkDB All DBs Position Unknown AA seq 1104 aa AA seqDB search MVPPSEETPLISQRSCSLSSSEAGVLHVLLPPRGPGPLQRLSFSFGDHSAEKLCVRAAKA SGILPVYHSLFALATEDLSCWFPPSHIFSVEDTGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLASAILDLPVLEHLFAQHRNDLVSGRFHVGLGLKEQGECLSLAVLDLARMAREQAQR PEELLKTVSYKACLPPGLRNLIQGLSFVTRRRIRRTVRQALCRVAACQADRHSLMAKYIM DLERLDPARAAETFLVGLPGVAGGQDAPGLLHVAGDSGIAWSSGEQEVFQPFCDFPEIVD ISIKQALRVGTAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTVDSRHYFC KEVAPPRLLEEVAQQCHGPITLDFAINKLKMGGSLPGSYVLRRSPQDFDSFLLTVCVQTP LGPDYKGCLIRCDPTGAYSLAGLGRPHSSLRELLAACWDGGLHVDGVALNLTFCCTPRPK EKSNLIVVRRGCSPPTSSPVQPHSGCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEAMDGEPRKTEVLLKVLDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVHLGALDTYLRKCGQLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA EGSPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GVTMPISTLDPAKKLQFYEERQQLPAPKWMELALLIQQCMAYEPGHRPSFRAVIRDLNNL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLGAGRLLLYASQICKGMEYLGSCRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYSDKSCSPSAEFLRMMGCERDIPALCRLLDLLAEGQRLPAPPACPGEVHELMKLCWAP SPQDRPTFSALGPQLDALWSGSQG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggtgcctccgagtgaggagacacccctgatctctcagcgctcttgcagcctctcatct tcagaggctggtgtgctgcatgtgctgctgccacctcggggccctggacccctgcagcgt ctatccttctcctttggggaccactcggctgaaaagctgtgtgttcgggctgctaaggcc agtggcatcctgcctgtgtatcactccctctttgctctggccacggaggacctgtcctgc tggttccccccgagccacatcttctccgtggaggacacaggcacccaagtccttgtctac aggctccgcttttacttccccaactggtttgggctagagaagtgtcaccgcttcgggctt cgaaaggacttggctagtgccatccttgacctgccagttctggagcacctcttcgcccag caccgcaatgacctggtgagcggccgcttccacgtgggccttggcctcaaggagcagggc gaatgtctcagcttggcagtgctggacctggccaggatggcccgcgagcaggcccagcgg ccagaggagctgctaaagaccgtcagctacaaggcctgcttgccccctggcctgcgcaac ctgatccagggcctgagcttcgtgactcggaggcgcattcggaggactgtacgccaggcc ctgtgccgcgtggccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg gacttggagcgactggacccggccagggccgctgagaccttcctcgtgggcctccccggg gttgctggtggtcaggatgcaccggggctgctccacgtggctggtgacagcggcatcgcc tggagttcaggagaacaggaggtcttccagcccttttgcgactttccagaaatcgtggac atcagcatcaagcaggctctacgcgttggcacggccggggagcaccgcctggtcactgtc accaggacagacaaccagatcctggaggccgagttccctgggctgcccgccgcgttgtcc tttgtggcgctcgtggatggctacttccggctgactgttgactctcggcactacttctgc aaggaggtagcaccgccgcggttgctggaggaggtggcgcagcagtgccatggccccatc accctggattttgcaatcaacaagctcaagatgggggggtcccttcctggctcctacgtt ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgtgttcagaccccc ctgggccctgattacaagggctgcctcatccggtgtgaccccacaggagcctactccctg gctggccttggccgaccccacagcagtctgcgagagctcctggcagcctgctgggatggt gggctgcatgtggatggggttgcactgaaccttaccttctgctgcacccctagacccaaa gaaaagtccaatctgattgtggtccggagaggttgcagcccacccacatcatcccccgtg cagccccactcaggatgccagctgagtcagatgacatttcacaagatacctgctgacagc ttggagtggcatgagaacctgggtcatggatccttcacgaagatttaccggggctgtcgc cacgaggccatggatggggagccccggaagacagaggtgctgctcaaggtgttggatgcc aaacacaagaactgcatggagtcattcctggaagcagcaagtttgatgagccaagtatcg taccagcatctcgtgttgcttcatggcgtgtgcatggctggagacagcatcatggtgcag gaatttgtacacctgggagcactggacacgtatctacgcaagtgtgggcagctggtgcca gccagctggaagctgcaggtgatcaaacagctcgcctatgccctcaactatctggaggac aaaggccttccccatggcaatgtctcagcccggaaggtgctcctggctcgggaaggggct gaggggagcccgcccttcatcaagctgagtgatcccggtgtcagccccactgtactaagc ctggagatgctcactgacaggatcccctgggtagctcctgagtgtctccaggaggcccgg acacttggcttggaagctgacaagtggggcttcggtgccacagtctgggaggtgttcagt ggtgtcacgatgccaatcagtaccctggatcctgccaagaagctccagttttatgaggaa cggcagcaactgcctgcccccaagtggatggagctggccctgctgatccaacagtgcatg gcctacgagccaggccacaggccctccttccgcgccgtcatccgtgacctgaacaacctt atcacgtcagactatgagctcctctcggaccccacacctggtgccttggcaccccgtgac gggctgtggaatggcgcccagctctatgcctgccaggaccctactatctttgaggagaga cacctgaagtatatctcacagctgggcaagggtaactttggcagcgtggaactatgtcgc tatgacccgctgggagacaacacaggtgccctggtggccgtgaagcagctgcagcacagt gggccagaccagcagagggacttccaacgggagatccagatcctcaaagccctgcacagt gacttcattgtcaagtaccgtggtgtcagctatggcccaggccgtcagagcctgcggcta gtcatggagtacctgcccagtggctgcctgagagatttcctgcagcggcaccgcgcacgc ctcggcgccggccgcctgctcctctatgcttcgcagatctgcaagggcatggagtatctg ggctcctgccgctgcgtgcaccgcgacctggcagcgcgtaacatcctggtggagagcgag acgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctggacaaagactat tacgttgttcgcgagccaggccagagccccattttctggtacgccccggagtccctctca gacaacatcttctcgcgccagtcggacgtctggagcttcggagtcgtcctgtacgagctt ttcacctacagtgacaagagctgcagcccctccgccgagttcctgcggatgatgggttgt gagcgagatatcccggctctttgccgcctcctggacctgctggcagagggccagaggctg ccggcgcctccagcctgccctggagaggttcatgagctcatgaagctatgctgggctcct agcccgcaagaccggcctactttcagtgccctcggaccccagctggatgcgctgtggagt ggaagccaggggtag

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