Rothia mucilaginosa: RMDY18_07110
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Entry
RMDY18_07110 CDS
T01144
Name
(GenBank) 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
rmu
Rothia mucilaginosa
Pathway
rmu00020
Citrate cycle (TCA cycle)
rmu00630
Glyoxylate and dicarboxylate metabolism
rmu00785
Lipoic acid metabolism
rmu01100
Metabolic pathways
rmu01110
Biosynthesis of secondary metabolites
rmu01120
Microbial metabolism in diverse environments
rmu01200
Carbon metabolism
rmu01210
2-Oxocarboxylic acid metabolism
Module
rmu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
rmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
RMDY18_07110
00630 Glyoxylate and dicarboxylate metabolism
RMDY18_07110
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RMDY18_07110
Enzymes [BR:
rmu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
RMDY18_07110
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
RMDY18_07110
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
RMDY18_07110
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
RMDY18_07110
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BAI64543
UniProt:
D2NSB7
LinkDB
All DBs
Position
complement(752475..756170)
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AA seq
1231 aa
AA seq
DB search
MEEAFNVPNLPEHLVPEEFAGNEWFVEEQYERYQKDKNLVDPSWWPIFETIDKALGGAGT
ASAAPAAAPAAPAAPAAPVATPAPAAPKPAVAPANPTPPAATKKAETVEPAEDKIVPLRG
PAKAVVTTMEESLTVPTATTVRAVPAKLLIENRAAINKYLASTRGGKVSFTHIIGYAVIR
AVAAMPSMNVTYGVDEKGKPVAIHNAHVNFGLAIDLPRPDGSRNLVVPNLKGAEQLSFRE
FWDAYNDIVKRGRNGALTIEDFRGTTVSLTNPGGIGTVHSVPRLSKGQAAIIGVGALEYP
AEFRGLSEKLITQQGLSKIITLTSTYDHRVIQGAGSGEFLKLVEHYLLGGDDFYDAIFRD
LKVPFEPVRWARDNHVDDAHEISKVARIQQLIHAYRVHGHLTAATNPVGYKMRSHPDLKL
ENYGLTLWDLDRVYPTGGFGGAERLPLRTILERLHEAYSGSLSVEYMYSEDPEVRAWFQE
RLERGVAKPTREEQLRVLSKLVEAEAFENFLQTKYLGQKRFSLEGGESLIPLLDAVLDKA
ANNDLKGVAIGMAHRGRLNVLTNIAGKSYAQIFREFSGTAAPYEGGSGDVKYHLGTEGVF
TSDSGKQTQVYVAANPSHLEAANTVLEGIVRAKQDVYREQGVEGYPVLPILIHGDAAFAG
QGIVMETLQMADLKAYTTGGTVHVVVNNQIGFTTLPNDGRTATHASDIARMTKAPVFHVN
ADDPDAVVRAARLAFEYRERFGRDVVIDLICYRRRGHNEADDPSMTQPKMYQDIDVLPST
RTLYAQDLVGRGDVSQEEADEVLDSYHSKLDAIFVETQSSAPAPAGAHVSGLELPAAQQN
TEVVHGGKTAISRETLQHIADAFGKAPEGFTVHKKLKKLMEQRVEMGRTGNVNWGMGELL
AFGSLLMEGTDVRMSGQDVQRGTFVQRHAVLHDHITDEEWSPLEHLSEDQGKFRIYNSFL
SEYGVLGFEYGYSVERPDSLVVWEAQFGDFANGAQTIIDEFVSSSEQKWGQRSSLVMLLP
HGYEGQGPDHSSARVERYLQLCAENNMTVACPSTPASHFHLLRRHSQHRPYKPLVVISPK
QLLRLKAAASSIEDFTEGSFQPVIGDRSGINPAQVERVVFVSGRLYYDLEAERERRGDTK
TAIVSVEQLYPLPEQEIKEQLALYSNATDVVWAQDEPANQGQWPFMALNLQPLIDRRMRL
ASRPAAASPAAGTGKLHAAEAEALLKQVFEG
NT seq
3696 nt
NT seq
+upstream
nt +downstream
nt
ttggaagaggcgtttaacgtgccaaatctgccagaacatctggtgcctgaggaatttgcc
ggtaacgaatggttcgttgaagaacagtacgagcgttaccagaaggacaagaacctcgtg
gacccttcatggtggcccatttttgagaccatcgataaggcgctgggaggcgccggtacc
gctagtgcagctcctgctgcggcacccgccgcgccggctgcacctgccgcacctgtagca
actcccgctcccgcggcaccgaagcctgcggttgcgcctgctaaccccacccctcccgct
gctaccaagaaggctgaaactgtggaacctgctgaagacaagattgtccccctccgcggc
cctgctaaggcagtcgtcacgaccatggaagagtcgctgactgtccccaccgcaaccacc
gttcgtgcggtccccgcaaagctgctcattgagaaccgcgcagccatcaacaagtacctg
gcaagcacccgcggcggcaaggtttccttcacccacatcattggttacgctgtgattcgc
gcagtggcagcgatgccctcgatgaacgtgacctacggtgtggacgagaagggcaagccc
gttgcaatccacaacgcacacgtaaactttggtctggctattgacctgccccgccccgac
ggctcccgcaacctggtcgttccgaaccttaagggtgctgagcagctgagcttccgtgag
ttctgggatgcgtacaacgacatcgttaagcgtggccgtaacggcgcgctgaccattgag
gacttccgcggcaccactgtttcgctgaccaaccccggtggtatcggtaccgtccactcg
gtgccccgcctctccaagggccaggcagcgatcatcggtgtgggtgctctggagtacccg
gcagagttccgcggcctgtccgagaagctcatcacccagcagggcctgtccaagatcatc
accctgaccagcacctacgaccaccgcgtcattcagggcgcaggttccggtgagttcctg
aagctggttgagcactacctgcttggcggcgacgacttctacgacgctatcttccgcgat
ttgaaggttcccttcgagccggtccgttgggcacgcgacaaccacgtcgatgacgctcac
gagatttccaaggttgcacgtattcagcagctgattcacgcgtaccgcgtgcacggtcac
ctgaccgcagcaaccaaccccgttggctacaagatgcgttcgcacccggacctgaagctg
gagaactacggcctgaccctgtgggatctggaccgcgtctacccgaccggtggcttcggc
ggcgctgagcgtctgccgctgcgcaccatcctggagcgcctgcacgaggcatactccggc
tccctgtccgttgagtacatgtactctgaggaccccgaggttcgcgcatggttccaggag
cgcctggagcgcggcgttgctaagcccacccgcgaggagcagctgcgtgttctctccaag
ctggttgaggctgaggcattcgagaacttcctgcagaccaagtacctgggtcagaagcgc
ttctccctggagggcggcgagtccctgattccgctgctggacgctgttctggacaaggcc
gctaacaacgacctgaagggcgttgccattggtatggcacaccgcggtcgcctgaacgtg
ctgaccaacattgctggtaagtcctacgctcagattttccgtgaattctccggcaccgca
gcaccctacgagggtggctccggtgacgtgaagtaccacctcggtaccgagggtgtcttc
acctccgattccggtaagcagacccaggtgtacgtggctgctaacccctcgcaccttgag
gctgcaaacaccgtgctcgagggtatcgtccgcgctaagcaggacgtctaccgtgagcag
ggcgttgagggctacccggtcctgccgatcctgattcacggtgacgcagcgttcgctggc
cagggcatcgtcatggagaccctgcagatggctgacctgaaggcgtacaccaccggcggc
accgtgcacgttgtggtgaacaaccagattggcttcaccaccctgccgaacgacggccgc
accgcaacccacgcctccgatattgcgcgtatgaccaaggctccggtcttccacgtcaac
gctgatgacccggatgcagtggttcgcgccgcacgcctggcattcgagtaccgtgagcgc
ttcggtcgcgacgttgtcattgacctgatttgctaccgccgccgcggtcacaacgaggct
gacgatccgtcgatgacccagccgaagatgtaccaggatattgacgtcctgccctcgacc
cgtaccctgtacgcacaggacctggtcggtcgcggcgatgtctctcaggaagaggcagac
gaagttctggactcctaccactcgaagctggacgctatcttcgtcgagactcagtcttcg
gcaccggctcctgctggcgcgcacgtttccggtctggaactgcccgctgctcagcagaac
accgaggtcgttcacggcggtaagactgcgatctcccgtgagactctgcagcacatcgct
gacgcgttcggtaaggctcccgaaggcttcaccgtccacaagaagctgaagaagctcatg
gagcagcgcgttgagatgggccgcaccggcaacgtgaactggggtatgggtgaactgctc
gccttcggttcgctgctgatggagggcaccgacgttcgtatgagcggtcaggatgttcag
cgcggtaccttcgttcagcgtcacgctgttctgcacgaccacatcactgatgaagagtgg
tcgccgctggagcacctctctgaggaccagggcaagttccgtatctacaactccttcctc
tctgagtacggcgttctcggcttcgagtacggctactcggtggagcgccccgactcgctc
gtggtgtgggaggctcagttcggtgacttcgcaaacggcgctcagaccatcattgacgag
ttcgtgtcctcctccgagcagaagtggggccagcgctcctcgctggttatgctgcttcct
cacggctacgagggtcagggtcctgaccactcctcggctcgtgttgagcgttacctgcag
ctctgcgctgagaacaacatgaccgtggcttgcccctcgaccccggcttcgcacttccac
ctgctgcgtcgccactctcagcaccgtccgtacaagccgctcgtggtcatcagccccaag
cagctgctgcgtctgaaggctgctgcgtcctccatcgaggacttcaccgagggttcgttc
cagccggtgattggtgaccgttcgggtattaacccggctcaggttgagcgtgtggtcttc
gtgtccggtcgtctctactacgatctggaagctgagcgcgagcgccgcggcgacaccaag
accgctattgtctcggtggagcagctgtacccgctgcccgagcaggagatcaaggagcag
ctggctctgtactcgaacgctaccgacgttgtgtgggctcaggacgagcctgctaaccag
ggtcagtggccgttcatggctctgaacctgcagccgctgatcgaccgccgtatgcgtctt
gcttcccgccccgcagctgcttccccggctgccggtaccggtaagctgcacgcagctgag
gctgaggctctgctcaagcaggtcttcgaaggctaa
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